A modern chemotherapy drug is more effective against advanced prostate cancer than a second targeted hormone therapy, with cabazitaxel extending men's lives by an average of 3 months. The study suggests that cancer's lethal ability to develop drug resistance affects treatment response across precision medicines.
A preliminary study from Children's National Hospital found no significant gluten transfer when tools like the same toaster or knives are used for both gluten-free and gluten-containing foods. Basic kitchen hygiene can further reduce gluten transfer.
A new study from the University of Arizona has identified a link between smartphone dependency and symptoms of depression and loneliness. Smartphone dependency predicts higher reports of depressive symptoms and loneliness, rather than the other way around.
A new Yale University study reveals that supermassive black holes grow in tandem with their host galaxies, influenced by the rate of star formation. The research provides a sharper understanding of the intricate relationship between these cosmic entities.
The TAILORx trial has shown that women with high Recurrence Scores (26-100) have a 93% chance of being cancer-free after five years, with those receiving chemotherapy having a significantly better outcome. The findings support the use of adjuvant chemotherapy to improve treatment outcomes in early breast cancer patients.
A new tool, HWISE Scale, measures household water insecurity in low- and middle-income countries. It provides actionable information to address the global water crisis, strongly associated with food insecurity, stress, and economic productivity.
A new blood test can identify complex DNA mutations in lung cancer patients, replacing invasive biopsies. The test has shown promise in detecting ALK genetic mutations, which respond well to targeted therapy.
Researchers used multifactor models to examine the impact of climate change on marine species in the US Northeast Shelf. The study found that more than 50% of species would experience a decline in habitat space, posing serious trouble for certain species like the Atlantic cod.
A recent study found that better access to clean water, sanitation services, and family planning can substantially reduce preventable child mortality in Africa. The analysis determined that large households are linked to worsening child health outcomes in developing nations.
A team of UC Davis researchers led by Vladimir Yarov-Yarovoy is developing a new class of peptides to treat chronic pain with minimal side effects. The goal is to identify the most effective peptide design that can selectively block pain-associated sodium channels without affecting other channels.
Researchers analyzed ancient crocodiles' shapes, modern diets, and fossil records to reconstruct their diets. Slender-snouted groups eat various prey, while broader-snouted groups consume larger prey up to their size.
Researchers discovered a correlation between statin dosage and osteoporosis diagnosis in a large patient dataset. Lower doses of cholesterol-lowering drugs were found to protect against bone resorption, while higher doses increased the risk of osteoporosis.
Review Commons aims to accelerate and streamline the process of publishing by conducting high-quality peer review of manuscripts before journal submission. Peer reviewers evaluate technical rigor, suggest improvements, and comment on potential value to specific communities.
Researchers from FEFU and international colleagues develop a multi-purpose sensor using nanotextured gold film, enabling trace-level molecule detection in liquid and gas environments. The sensor's sensitivity is attributed to resonant optical properties of nanoantennas created by femtosecond laser printing.
A new triple-therapy inhaler combining a steroid preventer, long-acting bronchodilator, and muscarinic antagonist significantly improved lung function and reduced moderate to severe asthma attacks. Patients with uncontrolled asthma who used the inhaler saw increased airway obstruction clearance and fewer exacerbations.
A new study found that halving red and processed meat consumption reduces LDL 'bad' cholesterol levels and heart disease risk by an average of 10%. Researchers discovered that even small changes to RPM intake can induce significant changes in LDL cholesterol, potentially reducing the risk of developing heart disease.
A new study from West Virginia University found that 78% of applicants claimed to have at least one publication, with 56% listing inaccurate or unverifiable publications. The researchers hope their findings can inform recommendations for improving the academic hiring process and increasing transparency.
Researchers have sequenced and assembled the red pineapple genome, revealing how natural and artificial selection shaped key traits. The study supports the hypothesis that some plants can be domesticated in a single step through clonal propagation.
Researchers have discovered that purple martins are roosting in small forest patches as they migrate from North America to Brazil. The birds seem to be intentionally seeking out these isolated habitats, possibly due to fewer predators than in larger forest areas.
Researchers at the University of Cambridge found that people who achieve weight loss of 10% or more within five years after diagnosis are more than twice as likely to go into remission. This suggests that significant calorie restriction and weight loss can reverse type 2 diabetes.
A new study finds that increasing levels of 'good' cholesterol reversed disease in the blood vessels of mice with diabetes, reversing atherosclerosis. The study also shows that raising functional HDL levels stopped inflammation and improved cardiovascular disease processes.
Researchers at UCSB have enabled identifying a person behind a wall using only WiFi transceivers outside, utilizing received power measurements of a WiFi link. The proposed approach achieves an accuracy of 84% in correctly identifying the person behind the wall, with potential applications in surveillance and security.
Researchers at the University of Bonn found that conventional washing machines in hospitals and potentially households can transmit antibiotic-resistant bacteria to newborns through clothing. The study highlights the need for higher temperatures during laundry to prevent transmission of dangerous pathogens.
A new study found that schools are breeding grounds for teenage vaping, with students accessing devices and peer influence playing a significant role. Schools can be effective in preventing teen e-cigarette use if they implement health education programs and restrict access to devices.
A study found that increasing vegetarian meal options led to a significant increase in sales, with diners who previously avoided vegetarian meals purchasing more after increased availability. The results suggest that expanding vegetarian options can reduce meat consumption and promote healthier eating habits.
Researchers at RUDN University have created non-toxic derivatives of chitosan with enhanced antibacterial activity, comparable to modern antibiotics. These novel materials can be used as preservatives in food coatings, providing a safer and more sustainable solution.
Teenage e-cigarette use is heavily influenced by parental and sibling attitudes, with flavors being a major draw for young users. Research also highlights the need for mandatory education on e-cigarette use among teens and increased regulation of flavored products.
Scientists discuss strengths and weaknesses of organoids as a model for human cortex, employing them to study developmental brain disorders. Researchers explore the viability of mini-brains in clinical research.
A new study reveals that cooking food fundamentally alters the microbiomes of both mice and humans. Cooking raw foods can harm certain microbes, while cooked foods may be more calorie-dense, affecting gut bacteria. In a human trial, participants showed significant changes in their microbiome after switching between raw and cooked diets.
A new treatment approach for metastatic prostate cancer has shown promising results, delaying disease progression by more than double and potentially extending lives. The treatment targets genetic alterations that enable cancer cells to repair themselves, leading to significant extensions in time before the disease grows and spreads.
A new study suggests that great apes, including chimpanzees, bonobos, and orangutans, possess a theory of mind, enabling them to understand others' mental states. The team observed that the apes anticipated an agent's actions based on their own experiences with different barriers.
Scientists from NUST MISIS and University of Rome Tor Vergata developed a new approach to design perovskite solar cells using MXene, increasing efficiency by more than 25% compared to original prototypes. The innovative material enhances charge extraction through interfaces.
Researchers at Oak Ridge National Laboratory developed a method to isolate specific microbes from complex human oral microbiome samples using antibody engineering. They successfully isolated three different species of TM7 and another uncultivated bacterial group, SR1.
A new AI system can accurately identify key findings in chest X-rays of pneumonia patients in just 10 seconds, significantly outperforming current clinical practice. This ultra-quick detection enables physicians to confirm a pneumonia diagnosis faster, allowing for timely treatment and reducing delays for severely ill patients.
Scientists created a human milk fat substitute from seed oil by modifying its metabolism to produce triacylglycerols with a specific fatty acid structure. This innovation could provide a cheap and sustainable source of human milk fat substitute for infant formula.
A UBC data science method analyzes citizens' access to hospitals and walk-in clinics, revealing large numbers without good access to health care. The study found that 80% of Portland residents, 51% of Seattleites, and 37% of Vancouverites lack sufficient healthcare access due to insufficient facilities and transit services.
Researchers designed a new structural design method that can transform flat layers into predetermined shapes in response to ambient temperature changes. The new structures can achieve complex configurations, such as transforming into a human face shape.
A new study by Michigan Medicine and University of Michigan found that nearly one in three low-income people with chronic illnesses discovered a new condition after enrolling in expanded Medicaid. Half of those with chronic conditions reported improved overall health within a year of coverage, with similar improvements in mental health.
Researchers from NUST MISIS created a unique composite material that can withstand temperatures up to 700°C, outperforming individual components in terms of microhardness. The material's multilayer structure, made possible by high-pressure torsion, enables improved thermal stability and strength.
Charcot-Marie-Tooth disease causes damage to the peripheral nervous system, affecting balance and motor skills. Researchers found that mutated enzymes take on an unusual shape, leading to unwanted interactions with nearby proteins and potential disease severity.
A study published in Nature Medicine suggests that whole genome sequencing of tumour cells can predict prognosis and identify effective treatments for patients with triple negative breast cancers. The technique reveals genetic signatures and mutations, providing clues to develop new drugs and improve treatment outcomes.
The integration of graphene and 2D materials with silicon technology promises to overcome current challenges and enhance device component function and performance. This could lead to breakthroughs in computational systems, non-computational applications, such as cameras and sensors, and even push performance gains in memory and data st...
A study found that patients with severe insomnia who took a sedative-hypnotic sleep aid showed significant improvement in reported insomnia severity and reduced suicidal thinking. The treatment was particularly effective in reducing suicidal thoughts in patients with the most severe insomnia.
Researchers from the University of Seville have discovered a new mechanism that makes it possible to understand premature ageing in cells with asymmetrical cell division. This mechanism is related to the distribution of microtubule-organising centres (MTOCs) during cell division.
A new study from UC Berkeley finds that hotter temperatures in the desert are causing birds to need more water to cool off, exacerbating a decline in species populations. Larger birds and those with insect or animal diets are most threatened by this heat stress.
Researchers detect non-linguistic experience in brain activity during reading, combining with linguistic information to decode sentence meaning. This breakthrough may guide future efforts in language disorders and artificial intelligence.
A new study finds that warmer tropical soils release more car-bon, leading to a 9% increase in atmospheric CO2 by the century's end. The increased microbial activity and changes in soil microbes also promote a positive feedback loop, exacerbating global warming.
Researchers found anticholinergic drugs like glycopyrrolate significantly reduced drooling, but caused adverse effects such as behavioral changes and dehydration. The study suggests choosing a medication with fewer side effects for those with severe motor impairment.
Physicists at Rice University have created a new alloy that exhibits unusual electronic properties when traversing the final frontier of quantum criticality. The cerium palladium aluminum alloy behaves like a spin liquid, a metallic system with exotic properties that can be found in other strongly correlated materials.
The NIH has initiated a collaborative influenza vaccine research network to develop more durable and broadly protective vaccines. The CIVICs program will support the development of universal influenza vaccines with longer-lasting protection against a wider variety of influenza viruses.
A major Canadian-led study has found that most adults can continue to eat red and processed meat without significant impacts on heart disease, diabetes, or cancer. The researchers concluded that a small reduction in risk was associated with reducing meat consumption by three servings per week.
Researchers at Lehigh University have created a new biofabrication method that allows for the regeneration of multiple tissues, such as cartilage and bone, within a single scaffold. This breakthrough could potentially treat debilitating conditions like osteoarthritis, which affects approximately 27 million Americans.
A study by Arizona State University found that urban agriculture can meet 90% of Phoenix's current annual fresh produce consumption. The city could also increase green space by 17% and reduce CO2 emissions by displacing energy use equivalent to 6,000 homes.
A new multidisciplinary study examines projected changes to the Santa Barbara coast and provides recommendations for adaptation. Key impacts include rising temperatures, increased flooding and erosion, and more frequent droughts.
The UC3M has developed a completely autonomous electric vehicle to replace combustion vehicles in the Timanfaya National Park. The minibus features level 5 autonomy, allowing it to operate without human control, and advanced AI perception systems for navigation and localization.
A panel of experts based on rigorous systematic reviews found little to no health benefits for reducing red or processed meat consumption. Most adults can continue their current levels of red and processed meat intake without negative health effects.
Researchers at Istituto Italiano di Tecnologia have developed a new technique called Optoceutics, which uses visible light to specifically direct the fate of tissue cells. This breakthrough has significant potential for regenerative medicine and treating cardiovascular diseases.
A phase III study showed that the combination of encorafenib, binimetinib, and cetuximab significantly improved overall survival (9.0 months) and objective response rates compared to standard care. The treatment was well-tolerated, suggesting a potential paradigm shift in treating BRAF-mutant metastatic colorectal cancer.
A researcher at OU Medicine is studying ways to predict who will get diabetes, so that physicians can intervene earlier. She aims to understand how a person's genetic makeup interacts with lifestyle factors like poor diet and lack of exercise to lead to diabetes.
A major meta-analysis found daily omega-3 supplementation reduced risks of heart attack and CVD events by 8%, with higher doses providing greater risk reduction. The study included over 120,000 adults in 13 randomized trials worldwide.