Researchers found that exposure to BMAA, a toxin produced by algae, can alter the structure of protein SOD1, leading to neurodegenerative disease ALS. The study suggests that studying patterns of SOD1 modifications may aid in developing lifestyle and preventative interventions for sporadic ALS.
The Compact X-ray Free Electron Laser (CXFEL) is a groundbreaking instrument that will help scientists explore various fields of research with spectacular clarity. The device, designed by physicist William Graves, is 100 times less expensive to build and operate than conventional XFELs, offering a precise tool for researchers.
A comparative microbiome study has identified significant differences in the composition of microbial communities between aquatic and terrestrial organisms. The researchers suggest that microorganisms may have played a key role in the evolutionary transition from purely aquatic life to life on land.
A study published in Neuron found that brain areas and patterns of interaction are similar regardless of navigation method, suggesting that sufficient information can be obtained from visual cues alone. The research suggests that even basic virtual reality systems may be useful in instructional applications.
Researchers developed a two-layer microchip that enables long-term tracking of stem cell development, overcoming technical challenges. The device allows for high-resolution imaging and manipulation of stem cells, enabling better control and understanding of differentiation processes.
A quarter of English teachers work more than 60 hours a week, with an average weekly worktime of 47 hours. This exceeds the OECD average and highlights the need for government reform to reduce teacher workload.
Most pups born in an elephant seal colony were produced by a small number of long-lived female seals, known as supermoms. These females dominated reproductive output, accounting for more than half of pup production.
Researchers found that female athletes had longer recovery trajectories and experienced more symptoms than males due to delayed presentation to specialist care. The study suggests that inequities in medical and athletic trainer coverage on the sidelines may contribute to these delays.
A study by neuroscientists from HSE University found that brain signals in the striatum and parietal cortex influence price adjustments in competitive markets. The results provide insight into the brain mechanisms at work when determining prices in such conditions.
Dr. Kristin L. Garlanger has been awarded the Ernest Bors, MD Award for Scientific Development by the Journal of Spinal Cord Medicine. Her research explores functional outcomes in patients with co-occurring traumatic brain injury and spinal cord injury, shedding light on ways to tailor rehabilitation protocols to improve outcomes.
Scientists have made progress in understanding dark matter by studying the interactions between light and gas in intergalactic space. Researchers used simulations and observations of distant quasars to analyze the properties of primordial black holes, which could provide evidence for their role in explaining dark matter.
A UCI team developed a new technique for predicting wildfires' final size, focusing on specific ignitions that pose the greatest risk of getting out of control. The model can forecast whether a blaze will be small, medium or large by its end, helping allocate scarce firefighting resources.
Researchers have successfully corrected the genetic mutation responsible for Duchenne muscular dystrophy using CRISPR gene editing in muscle stem cells. The edited cells regenerated and produced dystrophin, suggesting a potential method for lifelong correction of the disorder.
A recent study published in Stem Cells found that bone marrow cells treated patients showed enhanced recovery compared to those who received conventional treatment. Additionally, serial diffusion tensor imaging revealed the repair of motor nerve tracts in some patients, suggesting potential therapeutic benefits for stroke recovery.
A new study published in The Lancet Global Health found that nutrition programs have limited impact on cognitive skills and brain development compared to caregiving programs. Caregiving interventions such as parents playing games with their children significantly improved children's cognitive, language, and motor skills.
A large study found that people who walk the most live in areas with good public transport service and a higher density of households, services, and installations. Walking is associated with improved health and reduced air pollution.
Researchers discovered that some cancer cells survive chemotherapy by consuming neighboring tumor cells, providing energy to stay alive. This process helps senescent cancer cells initiate tumor relapse after treatment completion.
A collaborative study between University of Montana and Universidad de Concepcion in Chile found substantial gaps in scientific information relevant to conservation planning for threatened and endangered terrestrial mammals. The research highlights the importance of developing strategic research agendas for at-risk species worldwide.
A new study found that even short-term reduction in physical activity led to decreased cardiorespiratory fitness, increased waist circumference, and insulin resistance in healthy adults. Resuming normal activity levels reversed these effects, highlighting the importance of staying physically active to offset negative consequences.
Hyperbolic paraboloid origami has been found to exhibit structural bistability, allowing it to find a resting equilibrium in two different states. By tuning the folds of concentric squares, researchers can create structures with multiple stable configurations, enabling new applications in robotics and electronics.
Researchers at San Diego State University have discovered a beneficial bacterium that produces nanoscale syringe-like structures called the Death Star, which can deliver proteins to target cells and tissues in humans. This discovery could lead to novel therapeutics and vaccines for diseases such as cancer.
A new study has found that initiating antibiotics immediately before obtaining blood cultures significantly affects their sensitivity and ability to diagnose bacterial and fungal infections. This change in guidelines may reduce mortality rates from sepsis, a life-threatening condition with a 20% mortality rate.
A team of scientists at the University of Freiburg has found that the concentration of Argonaute proteins plays a central role in regulating the balance between stem cells and differentiated cells in plants. This balance is crucial for plant development, growth, and adaptation to environmental changes.
A research team at the University of Colorado School of Medicine has identified BRD4 as a central regulator of cardiac fibroblast activation. Chemical inhibitors of BRD4 potently block cardiac fibroblast activation, providing a potential therapeutic target for heart failure treatment.
The University of South Australia is leading a national push for academic integrity in Australian higher education, partnering with top experts to develop and deliver 20 workshops across the country. The initiative aims to promote good practices, prevent contract cheating, and safeguard the reputation of universities.
A team at OIST Graduate University reports a new approach to quantum gravity using a model that more closely matches our reality, including accelerating expansion. The free S-matrix predicts interactions between particles in de Sitter space, which may help explain realistic scenarios.
Researchers developed an exosome-based nanomedicine that increases tumor accumulation and penetration after intravenous administration. The biocompatible nanomedicines combine natural biomaterials with synthetic nanoparticles, demonstrating potential for improved anticancer drug efficacy.
A new study reveals that childhood trauma is associated with earlier and non-marital births, which can lead to poorer health later in life. The findings suggest that early trauma affects decision-making in ways that cannot be entirely controlled.
The University of Pittsburgh has been awarded a $10 million grant to create a network of precollege programs with accreditation standards, aiming to increase racial and ethnic diversity in STEM fields. The goal is to address gaps between underrepresented students in STEM fields, ultimately leading to more diverse STEM majors and jobs.
A new study published in PLoS One found that a kindergarten curriculum emphasizing social play and hands-on learning improves academic outcomes, self-control, and attention regulation. The approach also enhances children's joy in learning and teachers' enjoyment of teaching.
A study published in Heliyon found that early life experiences shape individuals' beliefs about themselves and the world, contributing to chronic obesity and frequent bingeing. Schema therapy model can help address these underlying issues by identifying and changing maladaptive schemas and coping modes.
Researchers propose using gravitational-wave observatories to detect axions, which could be a type of dark matter. Axions are predicted to modulate light polarization and can be detected with existing laser-based experiments, offering a cost-effective solution to the hunt for dark matter.
Researchers developed a new ultra-hypofractionated stereotactic body radiotherapy (SBRT) technique that safely delivers curative treatment for some prostate cancer patients in just one or two weeks. The study found similar levels of side effects and less overall toxicity compared to the current standard of care.
A new statistical approach revealed that forest fires in 19th and 20th centuries were man-made, driven by changes in forest management and vegetation. This finding highlights the need for adaptive forestry practices to address climate change.
Researchers found that high temperatures reduce snort-call display behavior in grassland birds, affecting mating success. The study suggests up to 10% decrease in display activity by 2100 due to global warming.
Hurricane Humberto is a very large storm stretching from Florida to North Carolina with a tail extending hundreds of miles into the western Atlantic Ocean. The storm is expected to bring heavy rain and large swells to Bermuda, with maximum sustained winds near 100 mph.
Patrick Sung, a leading BRCA expert, has received the National Cancer Institute's Outstanding Investigator Award, providing $6.1 million through 2026. His work focuses on understanding BRCA biology and its role in cancer initiation and progression.
A study by Vincent Richards and colleagues found that antibiotic-resistant genes are being transmitted from humans into animal species, including livestock, companion animals, and wildlife. This reverse zoonosis is facilitated by high bacterial genome plasticity, allowing bacteria to adapt quickly to environmental changes.
Researchers have discovered two short peptides that significantly improved memory and reduced physical changes in the brain of mice with Alzheimer's disease. The treatment uses a process of computer modeling and artificial intelligence to develop an optimized oral version of the drug, which could lead to new treatments for Alzheimer's.
Researchers at the University of Groningen have successfully created a two-dimensional spin transistor in graphene, which uses charge-to-spin conversion to generate spin currents. The spin transistor can be switched on and off using an electric field, enabling the creation of all-electrical spin circuits.
The Pew Charitable Trusts has awarded grants to six interdisciplinary research teams, combining expertise in virology, epigenetics, microbiology, and developmental biology to advance groundbreaking discoveries. The research projects focus on understanding complex biological processes, such as viral manipulation of host cells, genetic v...
Researchers at OIST Graduate University have developed a new method to detect electrons' transitions to quantum states using image charge detection. This technique has the potential to create a ten-centimeter chip, reducing the size of current quantum computers and bringing them closer to practical use.
Shear-thickening fluids can be manipulated using ultrasonic waves to soften them, opening up new applications for materials like concrete and ceramics. The approach uses acoustic transducers to break force chains responsible for thickening, allowing for dynamic tuning of the material.
A new study estimates that the Mount Tambora eruption significantly contributed to the 1816 'year without a summer', with observed cold conditions almost impossible without the event. The wet conditions were also more likely, increasing by 1.5-3 times without volcanic forcing.
The Penguin Genome Consortium has sequenced high-coverage penguin genome sequences, providing an unparalleled amount of information on the genomic landscape of all living penguin species. This study reveals key insights into the evolution of life on the ice and will help predict population trends under future climate change scenarios.
Scientists at Columbia University have successfully miniaturized medical imaging technology using a microchip, producing high-quality images with improved depth resolution. The breakthrough could lead to affordable handheld devices for disease diagnosis outside of hospitals in low-resource settings.
Biomedical engineers create biomanufacturing platform using bursting bacteria and shrinking capsules to produce targeted proteins, enabling flexible and efficient production of diverse biologics. The new technology simplifies the creation of protein complexes and offers an easy way to produce multiple proteins simultaneously.
A new study measures how much of coral nutrition comes from hunting, suggesting that corals may be eating more than expected. The research provides a more accurate view of coral diets and has big implications for reef survival during climate change.
A study by Georgia State University researchers found that creating mutations in the VP35 protein of the Ebola virus can make it unable to cause disease. The mutated virus was able to induce strong immune responses in non-human primates, protecting them from infection with wildtype Ebola virus.
A new study published in the American Journal of Clinical Nutrition found that a significant proportion of Mexican women of childbearing age have inadequate folate intake. The study suggests that fortification of staple foods with folic acid has improved overall folate intake, but still leaves vulnerable populations at risk.
A new electronic nose can identify lung cancer patients who will respond to immunotherapy with 85% accuracy, outperforming the current gold standard of immunohistochemistry. The non-invasive test detects chemicals in patient breath and provides instant feedback, potentially avoiding ineffective treatment and side effects.
A team of MIT researchers developed an AI-guided robotic platform to streamline the synthesis of small molecule organic compounds. The platform uses artificial intelligence-driven synthesis planning, flow chemistry, and a robotically controlled experimental platform to minimize human intervention.
A new two-year grant aims to improve outreach and care for people with lupus, focusing on historically black colleges and universities. The initiative includes educational outreach efforts, a patient navigator program to reduce hospital readmissions, and partnerships to increase understanding of health disparities among healthcare prov...
The Suomi NPP satellite's Visible Infrared Imaging Radiometer Suite (VIIRS) instrument provided an infrared image of Hurricane Kiko on Sept. 16, showing an elongated shape due to wind shear. Wind shear affects tropical cyclones by pushing against the rotating cylinder of winds, weakening rotation and intensifying the storm.
A new study found that socioeconomic factors significantly impact mortality and hospital readmission rates for patients with type 2 diabetes, but not type 1 diabetes. Patients from areas of high deprivation were more likely to die within six months of discharge.
New research by astrophysicists at the University of Kent reveals how matter discarded as stars die is recycled to form new stars and planets. The study found that elements such as carbon and oxygen are transferred through a process of fragmentation, providing vital clues about the emergence of life in our universe.
A new study demonstrates that a mutant live attenuated Ebola virus vaccine protects non-human primates against infection, targeting the immune-evasion function of VP35. The researchers developed a virus with three mutations in the VP35 protein, which plays a critical role in evading host immune responses.
A recent study published in JAMA found that surgeries using mesh support and removing the uterus via hysterectomy have comparable clinical outcomes after three years. The research recruited 183 postmenopausal women and showed a 12% better outcome for mesh surgery, with high patient-reported improvements in quality of life.
NASA's Terra satellite captured a visible image of newly formed Tropical Depression 11 over the western Gulf of Mexico on Sept. 17. The storm briefly strengthened into Tropical Storm Imelda, making landfall near Freeport, Texas, and triggering a Tropical Storm Warning.
Fungicides can negatively impact aquatic fungi growth, altering their role in decomposing organic matter and as a food source for higher trophic levels.