Markey researchers identify nuclear glycogen's role in cancer progression and find epigenetic connections between glycogen metabolism and gene expression. The study reveals new therapeutic targets to treat non-small cell lung cancers.
A study by the University of South Florida and Eckerd College found four billion particles of microplastics in Tampa Bay's waters, highlighting the need to address plastic pollution. Microplastics, tiny plastic particles less than 1/8 inch, come from various sources and can harm marine life through ingestion or surface damage.
BotSlayer uses an anomaly detection algorithm to quickly identify trending activity likely driven by bots. The tool can also generate a network map to illustrate how a topic is spreading over time, providing insights into influential accounts and disinformation attacks.
Researchers at the University of Texas at Austin discovered that Komodo dragon armor is designed to protect against other dragons, not predators. The unique bone structure, featuring four distinct shapes, provides extensive coverage and suggests that young Komodo dragons do not have armor until adulthood.
The study highlights significant gaps in knowledge about underassessed foods, which represent more than half of animal production and over 25% of total food globally. The researchers argue that a more complete global food assessment is necessary to develop sensitive and versatile local solutions to environmental and food security issues.
Researchers at Michigan State University have discovered that many core microbes on bioenergy plant leaves originate from the soil and remain consistent across seasons. The study suggests that these microbes play a crucial role in the plant's growth and health, and their phyllosphere microbiome can be targeted for cultivation.
A new national study by Penn Medicine found that hepatitis C-infected kidneys can function comparably to uninfected kidneys in patients who do not already have the virus. The study showed a significant increase in the use of HCV-infected organs, but raised questions about why these organs are still assigned lower risk scores.
Physicists have developed a novel method to create high-performance spintronic devices using organic molecules, which can be easily configured for different functions. The new fabrication method uses layers of molecules that can be painted or printed onto metals, offering a promising alternative to traditional materials.
A new two-minute focused cardiac ultrasound protocol can help veterinarians detect heart disease in cats earlier, potentially saving lives. The test, developed by researchers at Tufts University, has been shown to be successful in detecting moderate and severe heart disease with high accuracy.
Researchers found short-term impairments in brain-to-muscle communication and decreased memory performance after nine-minute boxing sparring sessions. The study suggests that routine impacts in sports like football and other combat sports may pose health risks.
Scientists have found that cryptochromes from migratory birds have evolved a mechanism that enhances their ability to respond to light, allowing them to sense and respond to magnetic fields under nighttime conditions. This discovery sheds light on how vertebrate cryptochromes function in low-light environments.
Researchers have discovered a feedback loop that reinforces atmospheric inversions, locking smoke in valleys and worsening air quality. Understanding this loop enables scientists to predict when fire inversions are likely to occur, aiding firefighters and residents.
Researchers at the Netherlands Institute for Neuroscience have found that congenital nystagmus is caused by electrical oscillations in retinal neurons. The study shows that defects in just a few proteins result in erroneous movement signals sent to the brain, leading to the oscillating eye movements characteristic of the condition.
Research reveals how breast cancer cells use exosomes to bypass the blood-brain barrier and spread to the brain. Exosomes trick endothelial cells into taking them up, allowing cancer cells to metastasize, and can also manipulate astrocytes to facilitate tumor growth.
Three innovative minds received the 2019 CNRS innovation medallist award for their groundbreaking work in reducing satellite size and propulsion units. Ane Aanesland and Dmytro Rafalskyi developed new propellant technologies, while Vance Bergeron created electrostimulation solutions to improve paralysis rehabilitation. Livio de Luca pi...
The Georgia Cancer Center at Augusta University has received a six-year $6 million grant from the NCI to improve access to clinical trials for minority and rural populations. The grant will be used to recruit patients to conduct multi-site cancer clinical trials and care delivery studies in their communities.
Researchers at Yale University have discovered that a woman's bone marrow plays a crucial role in determining her ability to start and sustain a pregnancy. Bone marrow-derived stem cells travel to the uterus, where they help transform the uterine lining for implantation, essential for embryo implantation and pregnancy maintenance.
A collaborative project between the University of Washington and UCB will explore ways to enhance community pharmacist engagement in epilepsy care. The effort seeks to address fragmented healthcare services and medication adherence issues affecting the 3.4 million people living with epilepsy.
A recent study suggests that osteocalcin, a hormone released by the skeleton, is necessary for the fight or flight response to be triggered in bony vertebrates. This finding challenges the long-held assumption that adrenaline drives this response.
Tokyo University of Agriculture and Technology researchers have developed a more efficient method to produce polyene substructures, a crucial framework in many natural products and pharmaceutical molecules. The new 'one-pot' solution eliminates lengthy preparation steps and excess waste, making the production process more economical.
A recent study by Radboud University Medical Center found that exercising at home using motivating apps significantly improves cardiovascular fitness and motor disability in Parkinson's patients. The cycling exercise program was more effective than stretching exercises alone, with a notable impact on disease progression.
Researchers found that sevoflurane improved survival rates and reduced bacterial presence in organs of mice with induced sepsis compared to isoflurane or no anesthetic. The study suggests a critical role for the type of general anesthesia used in treating sepsis.
Research reveals that bone-derived hormone osteocalcin plays a critical role in mediating the acute stress response, which is distinct from hormones released by the adrenal glands. Osteocalcin levels rise in response to stress, triggering physiological responses such as increased energy expenditure and heart rate.
The SUTD researchers developed a strong, flexible and scalable multi-robots system that can be used in intelligence, surveillance and reconnaissance operations. The system includes a combination of a wheeled ground unit and miniature robots, allowing it to be scalable and explore dynamic environments.
Researchers discovered LH dipeptide as a potent anti-inflammatory agent that inhibits the secretion of inflammatory cytokines from microglia, reducing brain inflammation and depression symptoms. Consuming foods rich in LH dipeptide may be a safe method for maintaining good mental health.
Researchers at Brown University discovered that diet can mitigate or exacerbate changes in the gut microbiome caused by antibiotics. In a mouse study, diet high in fiber and low in simple sugars protected certain beneficial bacteria from antibiotic harm.
Researchers at Duke-NUS Medical School have identified a network of RNA-binding proteins that play a key role in the formation of disease-causing fibrous tissue in the heart. Inhibiting specific proteins may help prevent or treat cardiac fibrosis, which underlies many heart diseases.
New optical security features use a two-piece metamaterial system to create difficult-to-replicate optical phenomena, making it harder to counterfeit money or intercept secure information. The approach offers improved forgery protection and can be used for various applications, including banknotes and identification cards.
A plant-based diet has been shown to reduce inflammation and improve symptoms of rheumatoid arthritis through various mechanisms. Studies have found that plant-based diets are low in fat and high in fiber, which can reduce inflammatory markers and promote healthy gut bacteria.
A recent study found no long-term negative effects of time-outs on children's emotional and behavioral health. Despite previous alarming claims, researchers did not find a relationship between reported use of time-outs and increased behavior problems.
A team of researchers directly observed charge transfer and intermolecular interactions in artificial photosynthesis on a picosecond scale. They used time-resolved attenuated total reflection spectroscopy in the terahertz region to reveal the process, which involves rhenium complexes and Triethanolamine solvent.
A phase 2 clinical trial found that combining temsirolimus with chemotherapy improved patient outcomes for patients with relapsed rhabdomyosarcoma. The treatment resulted in a 54.6% event-free survival rate, compared to 69.1% for those receiving temsirolimus.
Researchers found that suppliers can enhance competitiveness by engaging in 'peacocking' behavior, embedding unique capabilities into RFPs, and providing innovative solutions. Price is also important, but its importance varies by service and product.
Researchers from the University of Pennsylvania have developed a reconfigurable topological insulator that can route photons around defects, increasing efficiency and speed. This breakthrough has potential applications in high-capacity data routing for future communication networks.
A simple epidemiological model accurately predicts measles transmission dynamics in London over almost a century, accounting for historical events like the 1918 pandemic. The study's findings suggest long-term disease dynamics can follow simple rules, with implications for understanding other ecological phenomena.
A new study from the Journal of Marketing finds that firms' own social media posts surrounding customers' experiences can influence digital sentiment. Informational content offers a substantial means to improve customer sentiment in negative interaction event outcomes, increasing positive sentiment by nearly 20%.
Researchers at Harvard University have discovered the architecture of a copper-nitrenoid complex that can transform carbon-hydrogen bonds into valuable building blocks for chemical synthesis. This breakthrough could lead to more efficient and sustainable production methods for pharmaceuticals, household products, and other chemicals.
A new study suggests that popular mobile phone games can provide a tool to detect early signs of cognitive decline, including dementia. The research found that patterns of tap, swipe, and rotational gestures correlate with brain function.
Scientists have found a way to protect hair follicles from chemotherapy, potentially preventing hair loss. Researchers used CDK4/6 inhibitors to halt cell division and reduce damage caused by taxanes, common anti-cancer drugs that can induce permanent hair loss.
A Nemours study suggests genetic testing can personalize PPI dosing for eosinophilic esophagitis patients. This could improve efficacy and reduce side effects in up to 90% of children, according to researchers.
Astronomers have discovered a rare form of carbon monoxide in the dust and gas disc around a young star, revealing it to be much heavier than previously thought. This finding provides new insights into the formation of planets and challenges existing theories about planetary system formation.
Researchers developed physiological-sensing textiles that can be woven into sleep garments to monitor heart rate and breathing rhythm. The technology, dubbed 'phyjama,' extracts signals from pressured regions of the textile to get a more accurate composite reading.
A new MRI analysis technique using diffusion tensor imaging (DTI) helped predict thinking problems and dementia related to small vessel disease. Participants with the most brain damage were more likely to develop these conditions, and the scan accurately predicted three-fourths of dementia cases.
A fossil skull found in a Bavarian town in the 1770s has been recognized as Mystriosaurus laurillardi, a now-extinct species that lived in tropical waters during the Jurassic Period. Researchers have also identified another skull discovered in Yorkshire, belonging to the same species.
Scientists identified a molecular pathway that contributes to PAH's development, targeting the EYA3 protein for new therapies. Blocking this protein prevents dangerous lung artery thickening and reversal of vascular remodeling was seen in laboratory rat models.
Quanex IG Systems has licensed a low-cost method to produce insulating material from Oak Ridge National Laboratory, enabling improved thermal insulation performance in building products. The technology reduces energy consumption and generates less waste, making it an attractive solution for the industry.
Researchers found that dislocations negatively impact carrier dynamics, leading to a four-fold increase in electron lifetime when defect densities are reduced. Halide perovskite has improved from 3% to 25% efficiency over the past decade.
A systematic review and meta-analysis suggests that people with drug-resistant epilepsy have better prospects of being seizure-free if they undergo surgical treatment at an earlier stage. The study found a 15-21% higher probability of attack freedom for those who underwent surgery early compared to later stages.
A new study by UBC researchers provides a comprehensive model for hydrogen adoption in British Columbia, recommending a refuelling infrastructure and production plants to support the adoption of hydrogen-powered cars. The study sees significant growth in hydrogen demand every year, provided policies like B.C.'s carbon tax are maintained.
A study found that desensitization from peanut oral immunotherapy can be maintained by continuing a modest dose of peanut protein, offering more protection against allergic reactions. Participants who passed food challenges had lower initial levels of antibodies and indicators of allergic activity in their blood.
Rats learn to play a simplified version of hide and seek with humans, exhibiting strategic gameplay and learning to alternate roles. They develop unique vocalizations and show intense activity in the prefrontal cortex during game events.
A recent study found that a standardized medical school exam can bias the entry of diverse and qualified candidates into radiation oncology residency programs. The researchers suggest that using a holistic approach to evaluate applicants could help address these biases, incorporating emotional intelligence and other core competencies.
Researchers tracked 105 mako sharks over 12 years, finding that they return to the same productive waters in Southern California Bight each year. The study demonstrates impressive memory and navigation skills, with sharks traveling up to 90 miles a day and staying within specific temperature ranges.
Researchers at Trinity College Dublin have discovered new biological targets that may help combat cancers resistant to existing drugs. The study, published in Molecular Cell, reveals the importance of 'accessory components' in targeting Polycomb genes and their role in regulating cellular identity.
A study from Case Western Reserve University found that entrepreneurs who pitch their startup ideas with passion are more likely to entice investors. The researchers used functional Magnetic Resonance Imaging (fMRI) to examine the neural responses of investors' brains, revealing a causal relationship between passion and interest. As a ...
A mathematical model, EcH2o-iso, was developed to reflect the complex interplay between vegetation, soil, and water regimes. The model shows that certain types of vegetation can increase evaporation or promote groundwater recharge.
A study by Universidad Carlos III de Madrid reveals that olfactory and auditory stimuli can alter our perception of body shape. Exposure to certain smells, like lemon, makes people feel thinner, while others, such as vanilla, make them feel heavier.
A new study by Columbia University's Mailman School of Public Health found that socio-cultural values and beliefs around menstrual hygiene management are key to improving school environments for menstruating girls. The study identified gaps in research and provided recommendations for policy and practice changes.
A systematic review and meta-analysis found that the FDA approved drugs and devices based on nonrandomized clinical trials (10%), with estimated treatment effects higher for these approvals. The study's findings suggest that no clear threshold of treatment effect exists, which may lead to more frequent RCTs in the future.
A review of the literature suggests that adolescents with severe opioid use disorder can be treated with these medications as part of a comprehensive treatment plan. However, further research is needed to understand optimal treatment duration and retention rates.