Research found that partnerships between ICE and local police departments reduced Hispanic student enrollment by 10% in adopting counties, displacing approximately 320,000 students. The impact was concentrated among elementary school students, most of whom were likely born in the US.
A team of Portland State University researchers has discovered a possible one-pill cure for malaria using a compound based on a natural red pigment. The compound has shown effectiveness in killing the malaria parasite in mice and human blood with a single low dose.
An increase in elite Maya's preference for a maize-based diet made the population more vulnerable to drought, contributing to its societal collapse. The study found that a less flexible and less resilient system resulted from population expansion, agricultural intensification, and socially conditioned food preferences.
A new study from the University of Connecticut found that tweeting while watching TV decreases viewers' ability to become immersed in the narrative. College students who engaged in media multitasking reported lower levels of transportation into the content and intensified emotions compared to those consuming only one medium.
Scientists have re-measured a crucial physical constant with unprecedented accuracy, setting a new benchmark for physics research. The result could help explain nuclear fusion in the sun, understand element formation after the Big Bang, and improve particle collisions at CERN.
Researchers developed a computer model that simulates the metabolism of cancer cells, identifying effective drug combinations and predicting tumor growth inhibition. The model has been tested for colorectal cancer and shows promise for other types of cancer, potentially reducing development time and cost.
Scientists from the University of Bristol have developed a new platform for quantum simulators, enabling the creation of large-scale photonic circuits. The team demonstrated that small-scale silicon photonic circuits can generate and process unprecedented numbers of photons, paving the way for quantum machines to surpass classical supe...
Researchers developed a system of physics equations to model how water spills out over an earth dike, causing it to break and overflow. The new model takes into account the deformation of the dike's bed while water erodes it, providing more accurate predictions and improving flood safety.
A mathematical framework describes the ecology of a microbiome-host interaction landscape, allowing for global comparisons and understanding of diverse microbiomes' associations with similar health outcomes. The framework applies equally well to traditional genetic interactions.
Research by University of Wisconsin-Madison scientists found that irrigated farms in the region lower maximum temperatures by one to three degrees Fahrenheit on average, while increasing minimum temperatures up to four degrees. This cooling effect can significantly impact local climate, plant growth, and human health.
A meta-analysis of 15 million pregnancies found that the longer a pregnancy continues past 37 weeks gestation, the higher the risk of stillbirth. The risk increased with advancing gestation, with a 64% increase in stillbirths between 40-41 weeks and 3.18 stillbirths per 1000 pregnancies at 42 weeks.
Research examines language outcomes of children born preterm and full-term using different tests, revealing statistically significant group differences in language skills. Preterm children exhibited substantial grammatical difficulties not evident from standardized assessment.
A team of researchers has developed a method to generate mechanical vibration in microcantilever structures using spin current. The study demonstrates the potential for spin current to act as a driving force for micro machines without requiring electrical wiring.
Researchers found that mice lacking group-2 innate lymphoid cells in the small intestine prevented obesity after eating a high-fat diet. Conversely, reintroducing these cells led to obesity symptoms. The study suggests targeting small intestine ILC2s could be an effective obesity treatment approach.
The SULIS mission aims to understand the nature of solar eruptions and track magnetic clouds of charged gas. It will also demonstrate new technologies in space and precision alignment of small satellites flying in formation.
Researchers have discovered that a gene called Memo1 is necessary for organizing the scaffolding of brain cells, which plays a critical role in proper brain development. Mutations in this gene are linked to autism and can disrupt neural circuit formation, leading to disorganized layers and neuronal misplacement.
NASA's Terra and Aqua satellites detected Barbara as a powerful hurricane with maximum sustained winds of near 130 mph (215 kph). The storm is a category 4 hurricane on the Saffir-Simpson Hurricane Wind Scale, with hurricane-force winds extending up to 25 miles from the center.
A newly developed aerogel material can passively capture solar heat, reaching temperatures of up to 220°C in tests. This could enable lower-cost and simpler solar heat collection systems for various industrial and domestic uses.
A new study by Ohio State University finds that 81% of women who have experienced domestic violence have suffered a head injury, while 83% have been strangled. The research suggests that brain injury caused by blows to the head and oxygen deprivation are ongoing health issues for many survivors.
Researchers have successfully regenerated human retinal ganglion cells in a laboratory dish using lessons learned from rodent models. The discovery could lead to new methods of screening for drugs and genes impacted by glaucoma, potentially offering hope for vision loss patients.
A large study found that people with both physical illnesses and mental disorders experience a significant increase in frequent visits to emergency departments, compared to those with multiple physical illnesses or mental illness alone. This synergy between physical multimorbidity and mental disorders can lead to a greater impact on pu...
Researchers at IBS have successfully fabricated a single layer graphene film on large area copper foils with no adlayers, achieving adlayer-free and single crystal graphene. This breakthrough enables the creation of high-performance devices with consistent uniformity in the number of layers over large areas.
A new questionnaire has measured children's self-reported psychosocial, physical, and emotional needs in hospital settings. The top priorities identified by sick kids include feeling safe, getting enough sleep at night, being listened to, having places for parents to go for food and drinks, and family support.
Scientists create ointment to treat melanoma and Merkel carcinoma by suppressing tumor protein synthesis. The ointment's delivery system overcomes stability issues, allowing it to penetrate damaged skin cells and prevent relapse.
A recent study found that old-growth forests are less likely to experience high-severity fire than young-growth forests during wildfires. This suggests that old-growth forests could be used as biodiversity refuges to buffer the effects of climate change on fire regimes in the Pacific Northwest.
A new machine learning approach enables researchers to encode quantum mechanical laws into neural nets, simulating molecular motion billions of times faster than conventional methods. This breakthrough advances research in fields like drug development, protein simulations, and reactive chemistry.
A study published in Applied Ergonomics found that primary school-age children carrying loads up to 10% of their body weight experience minimal changes in movement, while exceeding this weight causes significant alterations. Pulling a backpack trolley with loads below 20% of body weight is recommended to avoid discomfort and injury
Researchers developed a stable cobalt(III)-nitrosyl complex, enabling controlled nitric oxide delivery to cells. This discovery has the potential to greatly impact treatment development for cardiovascular diseases, including vasodilation and enhanced neuroplasticity.
Researchers at UC San Diego are creating the world's first high-intensity twisted laser beams, also known as corkscrew light pulses. This achievement has potential applications in nuclear physics, astrophysics, and non-invasive tumor therapies.
A study on the cultural status of saltwater crocodiles in East Timor reveals a complex relationship between humans and animals. The research highlights the importance of incorporating traditional ecological knowledge into wildlife management to address severe human-crocodile conflict.
Researchers at OHSU discovered a short burst of exercise enhances brain function by increasing connections between neurons in the hippocampus. The study found that this 'gene' promotes small growths on neurons, allowing for better learning and memory.
Researchers found that people of all ages tend to overestimate the strength of others' emotions when actions are intentional, but not when actions are accidental. This 'egocentric bias' can lead to miscommunication and affect social behaviors like helping others.
A new article connects future population growth, agricultural development and infectious disease, highlighting the need for balance in agriculture to prevent disease outbreaks. Solutions proposed include improving hygiene, genetic variability, education, and predictive models.
In Russia, mentoring is now a widely accepted part of teacher training methodology, allowing young teachers to hone their skills and learn about new workplaces. Researchers conclude that this approach is becoming increasingly important due to constant socioeconomic and political change.
Scientists at EPFL have developed a new method for modifying cysteines on peptides and proteins using ethynylbenziodoxolones (EBXs), allowing for dual attachment points for new chemical groups. This enables the study of biological processes without interfering with them.
Researchers successfully demonstrated resonant absorption of terahertz radiation in commercially available graphene, enabling faster internet and a safe replacement for X-ray body scans. The high electron mobility in graphene makes it a promising material for ultrafast photodetectors.
MIT researchers have created a set of five fundamental parts that can be assembled into various functional devices, including a tiny walking motor. The new system uses 'digital materials' and offers an alternative approach to constructing robots, which could lead to the development of standardized kits for specific tasks.
Researchers developed an AI framework that detects rotational movements in clouds from satellite images, pointing to potentially threatening storm formations. The method achieved 99% accuracy and predicted 64% of severe weather events, outperforming existing detection methods.
Quantum sensors achieve extremely accurate results, surpassing conventional physics limits, enabling precision measurements of molecules and improving gravitational wave detectors. The new approach reduces measurement time by half while maintaining or doubling resolution.
Researchers identify DNA-PK as a master regulator of gene networks promoting aggressive prostate cancer behaviors. A clinical trial combining standard-of-care with a first-in-man DNA-PK inhibitor shows promising early results.
Researchers are using computer models developed by astronomers to create a rapid diagnostic test that can detect cancerous tissue without unnecessary biopsies. The technology has also shown promise in treating non-melanoma skin cancer, with simulations indicating that it could be effective in killing cancer cells.
New research from Duke University finds that reminding children of their various identities improves their problem-solving skills and flexible thinking about social groupings. This simple mindset switch can lead to better behavior in an increasingly diverse society.
Researchers from the University of Barcelona successfully synchronized two nanoscale optomechanical oscillators through mechanical coupling. The study demonstrates collective dynamics that can be controlled by acting externally on one oscillator only.
A study by Brigham and Women's Hospital found that a combination of high levels of dietary cholesterol with specific saturated fats exacerbates retinal damage in a preclinical model of diabetes. The research used an experimental rat model to examine the effects of different dietary fats on early molecular signs of inflammation and damage.
A large population-based study found that antidepressants significantly reduced mortality by 35% in patients with diabetes and depression. This significant reduction highlights the importance of addressing depression in individuals with diabetes, a condition where two to three times more people are at risk of depression.
A study by Penn State researchers found that low-density lipoprotein cholesterol levels below 70mg/dL increase the risk of hemorrhagic stroke. Participants with LDL levels between 70-99mg/dL had a similar risk, but those below 50mg/dL faced a significantly higher risk of 169%.
A whole brain imaging study found that excess grey matter in the brain can predict escalating drinking behavior in teens. Teens with more grey matter in certain regions were more likely to increase their drinking habits over time.
Mosquitoes have evolved to specialize in humans, recognizing distinct human odors through a complex blend of compounds. Researchers study the behavior, genetics, and brain structure of disease-carrying mosquitoes to understand this specialization.
Researchers from the University of Bath have conducted double-blind experiments showing that healthy mice pups can be born from sperm without acquired short RNA chains, challenging a proposed mechanism of epigenetic inheritance. The study undermines claims made by two 2018 papers that reported RNA addition was necessary for fertility.
Researchers at Tokyo University of Science discover that the anticonvulsant drug papaverine blocks the binding of high-mobility group box 1 (HMGB1) to its receptor, reducing inflammation in sepsis and cancer. The study uses a novel computer-based docking approach to find alternative uses for existing drugs.
The BioImage Archive is a large-scale resource hosting reference imaging data to facilitate global access and analysis. The archive aims to improve research quality, speed up scientific discovery, and advance knowledge in fields like human health, food security, and biodiversity.
Researchers studied clinician and older adult perspectives on communicating cancer screening cessation. Key findings include framing discussions around risks and benefits, patient empowerment, and addressing life expectancy concerns. The study aims to personalize cancer screening for elderly patients.
Rowan Martindale received a $570,000 NSF CAREER Grant to study ancient ocean ecosystems' responses to rapid global change. Her research focuses on the Early Jurassic's Moroccan High Atlas Mountains ecosystem collapse, which parallels modern climate change impacts.
Scientists at IDIBELL-ICO describe a novel mechanism of resistance to therapies that prevent blood vessel formation, which involves immune cells acting as tumor malignant elements. The study highlights the importance of targeting Sema4D and its secretion by macrophages to inhibit this mechanism.
Researchers found that gut microbes stimulate antiviral signals in non-immune lung cells to protect against the flu virus during early stages of infection. Enhanced baseline type I interferon signaling reduced flu virus replication and weight loss in mice.
Researchers found that intermittent fasting reduced pancreatic fat in mice, a key finding in the development of type 2 diabetes. The study suggests that excess weight-induced fat accumulation in the pancreas contributes to the onset of diabetes.
Researchers developed a micro-capillary injector that accelerates nanometer-scale structure fabrication using a supersonic jet of inert gas. The technique allows for rapid production of structures with high aspect ratios, suitable for applications in magnetic memory and quantum communication devices.
Scientists developed new theory capturing second sound phenomenon in quantum liquids, showing it can be faster than first sound. Theoretical approach uses squeezed-field path integral description, applicable to various phenomena at quantum-classical physics interface.
A new study from Oregon State University found that military veterans exposed to combat were more likely to exhibit signs of depression and anxiety in later life. The study suggests that combat experience has a unique impact on mental health trajectories in late life, independent of other health issues or stressful life events.
A recent study funded by the Morris Animal Foundation found nearly half of Mount Lofty Ranges koalas positive for Chlamydia DNA, while all Kangaroo Island koalas were free from the disease. The team's results suggest that Kangaroo Island may be a safeguard against further losses and even extinction due to chlamydial disease.
A team of researchers has discovered a new way to target the unique metabolism of drug-resistant parasites, using a molecule called rhodoquinone. This approach could lead to the development of new drugs that selectively kill parasites without harming humans.
A new paper argues that wildfire management through prescribed burning and restoration thinning could help save spotted owls in the West, similar to how it helped red-cockaded woodpeckers in the South. The strategy aims to reduce wildfire hazards and create more owl-friendly habitat conditions.
Astronomers have identified the atmospheric composition of a mid-size planet between Earth and Neptune for the first time using NASA's Hubble and Spitzer space telescopes. The planet, Gliese 3470 b, has a large rocky core surrounded by a deep crushing atmosphere mostly composed of hydrogen and helium.
A new study found that gastric cancer is affecting more young Hispanic people in the US, with poorer outcomes than older patients. Women under 40 were more likely to have diffuse-type tumours and stage IV disease at diagnosis, leading to a median overall survival of just 7 months.
Researchers found that people best liked the heroes they rated as most moral and least liked villains they rated as most immoral. The study, published in the Journal of Media Psychology, suggests that character morality is closely tied to how much people like them.
Since President Trump took office, FDA warning letters have fallen by a third, with significantly fewer issued during his second year. The decline in enforcement actions raises concerns among agency watchers and experts, who find the trend alarming despite the FDA's claim of ongoing regulatory efforts.
Researchers found that a specific carbohydrate attaches to a peptide hormone called atrial natriuretic peptide (ANP), regulating fluid balance and blood pressure. The study may lead to improved medications for high blood pressure.
A group of leading public health scientists calls for improved search engine and social media monitoring, as well as government support for mandatory immunization programs. They also advocate for correct dissemination of reliable vaccine information through various channels.
Researchers found that a specific esmolol-epinephrine ratio can provide cardioprotection while maintaining hemodynamic activity during myocardial ischemia and reperfusion injury. This combination therapy may be beneficial in treating patients with cardiogenic shock or cardiac arrest.
Researchers at Chalmers University of Technology have developed a unique method to study proteins trapped in glass, offering new insights into medicinal research. The method allows for the creation of a three-dimensional model of proteins in their natural environment, revealing their chemical composition and structure.
Researchers at KAUST have created a biohybrid material that performs well as an electrocatalyst, enabling the production of carbon-free fuels and green-energy applications. The material outperforms expensive metal-based OER catalysts in terms of efficiency and is environmentally friendly.
Researchers at IST Austria developed a new method to produce realistic water wave animations, now possible without sacrificing computational efficiency. The technique, which models wave-surface interactions, enables detailed scenes such as ripples forming around islands or boats passing by.
A new paper proposes a simple yet powerful model to understand why some water suppliers turn off their supply at certain times, highlighting both benefits and drawbacks of intermittent systems. The model can help guide global efforts to meet UN's Sustainable Development Goals and its Human Right to Water.
Researchers reviewed gene sequences of over 70,000 people and found that only 5% of patients with a TTN gene mutation developed dilated cardiomyopathy. Despite this, subtle differences in heart function were detected in those with the mutations, suggesting that pinpointing these genes may not be a reliable predictor of heart disease.
Researchers have localized a fast radio burst, FRB 190523, to a galaxy 7.9 billion light-years away, providing new clues in the ongoing cosmic mystery. The discovery suggests that every galaxy, including our Milky Way, can generate an FRB.
A study published in Tobacco Control found that only 1 in 6 accredited US colleges and universities were completely smoke or tobacco-free by 2017. This leaves a significant number of students, faculty, and staff exposed to secondhand smoke.
A new ultrasensitive chemiluminescence-based method has been developed to rapidly detect Salmonella and Listeria monocytogenes. This test can be carried out in the field and requires no containment laboratory, significantly faster than conventional methods.
Researchers from Mount Sinai highlight the importance of multidimensional data for stratifying a complex disease like asthma. Carefully designed, integrated multi-'omic' studies could accelerate precision medicine for asthma patients by defining asthma subtypes through transcriptomics and other omic approaches.
A new study shows that niraparib can extend life for women with ovarian cancer who have undergone multiple rounds of chemotherapy. The study found that 27% of patients responded well to the drug and averaged 9.2 months until disease progression, offering hope for a meaningful treatment option.
A recent study found that the brain becomes desensitized to background motion, making it easier to distinguish smaller moving objects in the foreground. Older adults can improve their motion segregation abilities through visual training, narrowing the gap with younger counterparts.
Aarhus University researchers suggest a previously overlooked process explains methane's consumption on Mars, leading to doubts about its presence and potential biosignature. The new mechanism involves erosion and chemistry, affecting the possibility of life on or near Martian surface.
A new species of jumping spider was named Jotus karllagerfeldiI after Karl Lagerfeld due to its distinctive black-and-white colors resembling the designer's style. The species was discovered in the Godeffroy Collection, alongside seven other new species found across Australia.
A team of researchers has identified a tissue-specific non-coding RNA called NEAT1 that regulates memory formation in the hippocampus region of the brain. Increasing NEAT1 levels in younger mice impaired learning and memory, while decreasing NEAT1 levels improved cognitive function.
Researchers found that injecting tiny beryllium pellets into the plasma could trigger small eruptions called ELMs, stabilizing fusion reactions. This technique could potentially reduce the risk of large ELMs and damage to the ITER facility.
A new biomaterial, mycokarst, made from mushroom spores has been developed to repair and strengthen building materials in extreme conditions. The material was tested on karst formations and found to be highly durable, capable of withstanding loads of up to 40 MPa.
A study by University of Turku researchers found that women are more likely to volunteer for all-female paramilitary organizations if they have brothers or husbands serving in the military. The study suggests that bonding with larger communities, such as the nation state or religious groups, can arise from psychology mechanisms designe...
The world faces an urgent need for a global agenda to manage sand, a key ingredient in modern life. With rapid urbanization and population growth driving high demand, the global sand extraction rate is projected to increase by 300% between 2000-2100.
Researchers used an extremely bright mid-infrared laser to perform spectroscopic ellipsometry, capturing high-resolution spectral information in under a second. The new approach offers insights into quickly changing properties of samples and could improve manufacturing processes and scientific discoveries.
Researchers at the University of Pennsylvania have discovered that food and drugs can hijack the brain's reward circuits, which are also responsible for signaling hunger. This knowledge could inform the creation of more effective weight loss drugs or addiction therapies with fewer unpleasant side effects.
A team of researchers has found a balance between hot gas, stars, and other materials in galaxy clusters. The study validates the prevailing cold dark matter theory and provides insight into the relationship between ordinary matter and dark matter.
A new study found that genetic variation in the serotonin transporter gene affects brain mechanisms that influence anxiety and depression. The research suggests that personalized therapies could be developed based on an individual's genetic profile.
Researchers at OIST and Osaka University develop an artificial cell system that interacts with histamine, a natural chemical compound. The system uses a riboswitch to turn on a gene inside the cells, which can eventually be used to release drugs in response to histamine signals.
Adolescents exposed to high levels of pesticides are at increased risk of depression, according to a new study. The study found that lower levels of the enzyme acetylcholinesterase, which measure pesticide exposure, were associated with more symptoms of depression in teens.
A UH researcher reports that the formation of abnormal hemoglobin clusters in red blood cells may be a crucial step in developing treatments for sickle cell disease. The study suggests that inducing similar-sized clusters in liquids and solids could have applications in nanotechnology and industry.
Researchers at Mainz University have developed a new method to detect axions, a type of dark matter, using the Cosmic Axion Spin Precession Experiment (CASPEr) program. By exploiting nuclear magnetic resonance and sophisticated shielding, the team aims to identify spin changes caused by dark matter, which can be distinguished from thos...
A new IOF review emphasizes the importance of long-term follow-up to maintain bone health in childhood cancer survivors. The study highlights the need for careful monitoring and management to prevent premature onset of low bone mineral density and improve fracture risk.
Researchers at LMU discovered that Toxoplasma gondii utilizes a previously unrecognized mode of motility, where it secretes membrane material and recycles it into the cell membrane through endocytosis. This process generates a 'fountain-like' flow of membrane material that contributes to the parasite's propulsion along the substrate.
Researchers discovered a third fewer cells in surface waters of South Pacific Gyre compared to Atlantic ocean gyres. They found familiar microbes like Prochlorococcus and SAR11, but also an unexpected species AEGEAN-169 in surface waters.
Research reveals a proliferation of JUUL-related content on Instagram that appeals to young people through product promotion, nicotine and addiction content, and youth culture references. The study's findings suggest that strong regulatory action is needed to restrict promotional efforts for e-cigarette products on social media platforms.
Scientists use Coherent Hard X-ray Scattering to study thin film growth, producing a 'movie' that depicts the process more accurately than traditional techniques. The research could improve the performance of organic solar cells and provide insights into the quality of films.
A study by researchers at Technical University of Munich found that fungal communities have darker mushrooms in cold climates, suggesting a correlation between coloration and temperature regulation. This mechanism may improve reproduction by allowing fungi to harness solar energy.
A two-decade study on identical twins and triplets adopted as infants sheds light on the balance between nature and nurture in child development. The research aims to clarify historical misconceptions about twin studies and offers lessons for contemporary scientific inquiry.
A year-long study found that free-roaming mongrel dogs exhibit high levels of aggression in the middle of their dominance hierarchy, contrary to predictions. The researchers suggest that the complexity of pecking order in this crowded area leads to increased aggression.
Children with obesity participating in a fun-driven aerobic exercise program showed no significant improvement in mood compared to those in a sedentary after-school program. However, the sedentary group reported depressive symptoms decreased over time, possibly due to social interactions and friendships developed during the program.
A team of researchers at Texas A&M University has developed a way to control the hydrophobicity of surfaces inspired by nature, which could have widespread applications in the biomedical field. The 'nanoflower' design uses atomic defects in nanomaterials to repel water and clean surfaces.
A new study by the Francis Crick Institute found that antibiotics can wipe out early flu resistance and leave the lung vulnerable to viral infections. Gut bacteria help maintain a first line of defense in the lining of the lung, but antibiotics can destroy this defense.
Researchers found that 150,000 Ontarians experience a concussion each year, with children under 5 and adults over 65 being at higher risk. Summer months see a peak in concussions, with rural communities experiencing a higher rate than non-rural areas.
Researchers found that social isolation triggers aggression in spiders after they disperse, reversing their initial social behavior. This discovery challenges the long-held assumption that aggression is a precursor to dispersal in spiderlings.
Researchers discovered that millet farmers from northern China introduced cold-tolerant barley to the plateau around 3600 years ago. This genetic legacy has contributed significantly to the current genetic landscape of Tibetans.
Researchers at Temple University and UNMC eliminate HIV DNA from animal genomes using CRISPR-Cas9 technology, achieving a critical step towards a possible cure for human HIV infection. The study combines gene editing with LASER ART therapy to suppress HIV replication and eradicate the virus from cells.
A new epidemic forecast model developed by Texas A&M researchers can accurately predict disease trajectories by taking into account human behavior. This allows for more effective resource allocation during outbreaks, reducing the risk of over-preparation and public mistrust.
A study from Joslin Diabetes Center found that a minority of patients treated for decades with type 1 diabetes may have monogenic diabetes, which can be treated with oral drugs. The research suggests screening for genetic mutations in young people diagnosed with type 1 diabetes to identify potential treatment options.
A supermassive black hole at the centre of jellyfish galaxy JO201 is stripping away gas and throwing it out into space, accelerating the suppression of star formation. This process, known as ram-pressure stripping, has caused a brief increase in star formation due to the compression of clouds of gas.
Researchers from Queen Mary University of London found that the risk of stillbirth increases with each week of pregnancy after term. Women who continue their pregnancy to 41 weeks' gestation face a low but increased risk, equivalent to one additional stillbirth for every 1,449 pregnancies compared to delivering at 40 weeks.
A DNA test of a tooth fragment from Jeff Weakley's foot, retrieved after a 24-year blister, identified the blacktip shark species responsible for the 1994 bite. The study aims to improve bite mitigation strategies by providing more precise data on unidentified species.
A statewide initiative in California resulted in a significant decrease in the rate of kindergartners entering school without up-to-date vaccinations. The study found that the rate decreased from 9.84% to 4.87% between 2013 and 2017, likely due to changes in vaccination policies.