Researchers at the University of Calgary have developed a new method to analyze cellular behavior in sepsis infections, identifying 18 different clusters of behaviors involved. This breakthrough could lead to targeted therapeutics and improved survival rates for patients.
Canadian agri-food leaders recommend strengthening food infrastructure, improving preparedness, and building resilience to protect against geopolitical threats, biological threats, trade disruptions, and supply chain vulnerabilities. The report outlines seven key recommendations to ensure Canada's long-term food resilience.
Researchers at the University of Calgary have developed a novel CAR T-cell therapy called GCAR1, showing strong preclinical and early clinical promise in treating sarcoma and other cancers. The therapy has been tested on two Canadian patients, with one patient experiencing significant prolongation of life expectancy by 18 months.
A new study analyzing over 11,000 YouTube videos and comments found that online discussions surrounding avian influenza transformed scientific information into broader debates involving institutional trust, politics, and alternative interpretations of disease risk. The analysis identified dominant themes, emotional patterns, and shifts...
Two studies found that certain fungal species in the gut play a key role in immune dysregulation and pediatric allergic diseases, positioning the infant mycobiome as a promising target for therapies. Infants' early-life antibiotic use may have a direct impact on these fungi, leading to immune dysregulation and allergic asthma.
A UCalgary study shows that removing a single gene makes colon cancer cells vulnerable to immunotherapy, allowing them to recognize and attack tumours. The research led by Dr. Arshad Ayyaz discovered that cancer cells secrete a protein that hides from the immune system, but knocking out this gene makes them visible.
Researchers from the University of Calgary and international collaborators explored the zoonotic potential of CWD in controlled laboratory settings. The study found that infectious prions can still be present and transmissible even without obvious clinical signs, highlighting the need for continued surveillance and research.
A recent study published in Cell has found that certain plants actively reduce their ability to take up iron when experiencing drought stress. This shift is driven by changes to plant roots that downregulate both immune systems and iron uptake machinery, allowing specific bacteria to thrive.
Researchers measured hydrogen's hyperfine splitting in antihydrogen, a tiny energy difference that could reveal a hidden difference between matter and antimatter. The study confirmed the symmetry between the two, but future measurements aim to improve precision and potentially break current physics understanding.
A UCalgary study found that Engleman and white spruce trees use the same genetic tool kit to survive in variable climates across the Canadian Rockies. The research provides insight into species adaptation and evolution, shedding light on how trees thrive in different environments.
A massive 481-meter-high landslide-tsunami hit an Alaskan fjord, providing valuable lessons for those in steep, mountainous terrain. The event, triggered by glacial retreat, highlights the importance of improved monitoring to mitigate climate-related hazards.
A University of Calgary-led study found that children with genes predisposing to migraine are at higher risk of developing more severe headaches after a concussion. The research identified specific genetic mutations and family history of migraine as associated risks.
A University of Calgary-led study found that multiple myeloma tumour cells adapt in multiple ways to become resistant to treatment, highlighting the need for personalized cancer therapy. The research aims to develop next-generation treatments designed to anticipate and overcome these changes.
A new 4D digital heart model has been shown to improve patient outcomes in cardiac resynchronization therapy (CRT) for heart failure. The model, developed at the University of Calgary, enables personalized pacemaker placement, leading to a 10.8% increase in heart function compared to standard care.
A large E. coli outbreak in Calgary daycare centers resulted in 285 children becoming infected, with daily laboratory monitoring and treating dehydration preventing complications and potentially saving lives. The study found that this approach reduced the number of children who developed life-threatening hemolytic uremic syndrome.
A UCalgary study found that adding high doses of vitamin B3 to the treatment plan may help rejuvenate compromised immune cells to kill tumour cells. The clinical trial showed promising results, with 82% of participants free of cancer progression at six-months.
A University of Calgary-led international research team has identified the runt-related transcription factor 1 (RUNX1) as a genetic factor influencing opioid responses. People carrying the RUNX1 variant require higher doses for pain relief and experience more intense withdrawal symptoms.
Researchers mapped the northern sky across different radio frequencies to create a high-quality dataset of the galaxy's magnetic field structure. The data provides insight into how the magnetic field evolved and includes a new three-dimensional model for the reversal in the Sagittarius Arm.
A UCalgary researcher has created an AI-based early detection system for river-borne pathogens, including whirling disease in trout and salmon. The model uses environmental variables like air temperature to predict pathogen distribution with impressive accuracy, even with limited data.
New research from The Simpson Centre reveals Canada's canola sector faces structural vulnerabilities due to reliance on China and the US for exports. Limited capacity to reallocate shipments to alternative destinations creates distinct risks across different segments of the canola value chain.
The Simpson Centre's analysis reveals mixed results when comparing Canadian farmers' policy priorities with measures introduced in the 2025 federal budget. While the budget responds to several concerns with improved AgriStability coverage and trade investments, critical gaps remain in addressing fuel taxation, interprovincial trade bar...
A new insulin delivery technology has been found to improve glucose control during pregnancy for women with Type 1 diabetes, reducing the risk of complications for both mother and baby. The study, led by University of Calgary researchers, found that this technology resulted in a three-hour per day improvement in the desired glucose ran...
Researchers are collecting toenail clippings from Canadians to estimate a person's lung-cancer risk based on long-term radon exposure. The study aims to provide critical data for early screening and diagnosis of lung cancer.
Researchers have developed an implantable system to stabilize blood pressure in people with spinal cord injuries. The therapy, which involves delivering finely tuned electrical stimulation, has been shown to restore blood pressure stability and prevent life-threatening spikes.
A groundbreaking trial published in New England Journal of Medicine demonstrates the benefits of surgical treatment with a shunt for idiopathic Normal Pressure Hydrocephalus (iNPH) in older adults. Eighty percent of participants showed significant clinical improvement, including improved walking speed and balance.
Researchers at UCalgary have found that neurons play a critical role in reducing harmful lung inflammation, which leads to pulmonary fibrosis. The discovery opens up opportunities for using neurological therapies to treat the disease, and preliminary studies suggest that boosting the function of these nerve cells could improve scarring.
A UCalgary-led study found that providing anti-vomiting medication to children with frequent vomiting from an intestinal infection helps them recover at home. The research identified ondansetron as an effective treatment approach for these children, reducing the need for hospitalization and improving symptom management.
A new species of dinosaur, Khankhuuluu, is described as the closest-known ancestor to the giant Tyrannosaurs. It was a mesopredator that used speed and agility to take down its prey.
Research reveals that Alaska wolves consuming sea otters have unprecedented mercury levels, potentially driven by climate change and coastal ecosystem changes. The study, led by University of Calgary ecotoxicology expert Ben Barst, found higher mercury concentrations in wolves from Pleasant Island compared to mainland Alaskan wolves.
Researchers from UCalgary and Chinese University of Hong Kong found that IBD progresses through four predictable epidemiological stages as it spreads globally. The study forecasts a major rise in IBD prevalence in Canada by 2045, with countries in North America, Europe, and Oceania reaching Stage 3 (compounding prevalence). Developing ...
The discovery of large carbon deposits in Gale Crater suggests that ancient Mars had a CO2-rich atmosphere, which supported liquid water and potentially life. Scientists are now trying to determine how much of this CO2 was sequestered, and whether it impacted Mars' ability to stay warm.
Researchers at the University of Calgary investigate the effectiveness of transcranial magnetic stimulation combined with intensive speech therapy for treating poststroke aphasia. The study found significant improvements in speech, confidence, and mood among participants, offering new hope for those affected by stroke.
A global study led by UCalgary researchers found that one in five people who experience a minor stroke or TIA will have another stroke within 10 years. The study analyzed data from over 171,000 patients across four continents and shows a persistently high risk of future strokes for at least a decade.
Researchers at UCalgary have discovered a protein called CD2AP that may hold the key to reducing Alzheimer's disease risk. Levels of this protein are lower in patients with AD, and its absence affects memory function, particularly in males. The study suggests a sex-dependent link between vascular system health and brain function.
Researchers found that female rodents experience heightened pain sensitivity due to activation of Panx1 channels releasing leptin, a hormone associated with increased pain sensitivity. This study aims to personalize treatment for patients and may explain the over-representation of women experiencing chronic pain compared to men.
Researchers at UCalgary suggest a holistic approach to conservation by analyzing individual movement patterns of caribou. The study identifies six distinct behavioural groups that deserve separate conservation actions, providing a framework for habitat protection and restoration strategies.
Researchers analyzed data from three trials and found nerinetide provided a clinically significant benefit to patients. The findings suggest that treating early, fast, and administering the drug can lead to improved patient outcomes.
UCalgary researchers confirm that endovascular thrombectomy (EVT) is not effective for patients with blockages in medium-sized blood vessels. The ESCAPE-MeVO clinical trial found no improvement in outcomes for these patients compared to standard care. EVT was previously shown to improve patient outcomes after large-vessel strokes.
A collaborative effort investigates the Sikkim Himalaya flood, exploring its drivers, causes, and downstream impacts. The research aims to inform disaster risk reduction and build resilience in vulnerable regions.
Researchers applied ACE questionnaires to select Marvel and DC characters, finding that childhood trauma does not determine heroism or villainy. The study suggests that using fictional characters can help address child abuse and trauma in a non-confrontational way.
Researchers from UCalgary and around the world have discovered that early humans, Homo erectus, were able to thrive in extreme environments, including hot and dry periods. This finding changes our understanding of human adaptability and suggests that ancient humans had a wider range of survival capabilities than previously thought.
UCalgary scientists reveal a whitish grey patch associated with aurora borealis, suggesting a heat source and more complex aurora dynamics. The discovery uses advanced camera technology to capture true color images of the night sky.
A team of UCalgary researchers, led by Dr. Anthony Schryvers, has developed a new vaccine to protect cattle from hemorrhagic septicemia, a deadly bacterial disease that destroys livestock and livelihoods. The vaccine is designed with a long-lasting immune response and has been patented.
Researchers used genomic technology to study Marjolin's ulcer, a rare and highly aggressive skin cancer that grows on chronic burn wounds. The study reveals insights into how keratinocytes switch their function to become cancerous, creating a fertile environment for tumor cells to grow and spread.
A national report reveals nearly 18% of Canadian homes have radon levels above 200 Bq/m³, increasing lung cancer risk. Canadians are among the most highly exposed to radon, highlighting the need for urgent action to address this public health concern.
Researchers at the University of Calgary found that girls and non-binary youth who experience teen dating violence are at an elevated risk for concussion. The study, published in Journal of Adolescent Health, analyzed data from Canadian Grade 9 and 10 students and found that one in three experienced physical, psychological, and/or cybe...
Researchers at the University of Calgary are conducting a clinical trial using probenecid, an anti-gout medication, to treat debilitating opioid withdrawal symptoms. The study's lead authors aim to develop a potential treatment for the disabling symptoms of opioid withdrawal, which can be crippling.
A UCalgary study found that involving community pharmacists in prescribing blood thinners for individuals with undiagnosed or undertreated atrial fibrillation can improve stroke prevention. The study showed a 34% increase in optimal blood thinner use among at-risk individuals.
A new digital tool, KDpredict, developed by University of Calgary scientists can more accurately predict the risks of kidney failure and death in adults with moderate-to-severe chronic kidney disease. The tool uses four variables readily available in clinic practice to calculate one-to-five year risks of kidney failure and death.
Research reveals 66-75% of people experiencing homelessness have underlying mental health conditions, with males affected more severely. The study emphasizes the need for integrated interventions and gender-specific approaches to address homelessness and related health disparities.