Researchers analyzed 60 hours of Netflix content, finding that it often portrays only violent injuries as causing pain, neglecting medical procedures and chronic pain. The study highlights the need for more diverse and inclusive portrayals of pain in media to better support adolescents' experiences.
University of Calgary researchers found that communication between the lungs and brain triggers symptoms of sickness, changing treatment approaches for respiratory infections and chronic conditions. The study also suggests targeting neurological pathways alongside antibiotics to combat infections.
A University of Calgary-led study reveals that vaping and other lifestyle factors, including meal irregularity, screen time, and household smoking, are associated with frequent headaches in children and adolescents. Frequent recurrent headaches can significantly affect quality of life.
Researchers found elevated radon gas levels in rural homes near drilled groundwater wells, with a 30% higher exposure risk compared to urban areas. Regular testing is crucial for mitigating radon-related lung cancer risks in rural communities.
Researchers have developed One-pot DTECT, a compact kit that can detect genetic signatures with high accuracy, enabling rapid point-of-care diagnosis for various applications. The tool has been shown to identify genetic mutations in sickle cell anemia patients and carriers with 100% accuracy.
A Canadian study found that infants exposed to biologic agents during pregnancy have normal immune development and can safely receive the rotavirus vaccine. The study, involving 191 infants across six sites in Canada, aimed to change vaccination guidelines to protect more babies from severe illness.
Researchers used spatial transcriptomics to analyze cancer cells at the edge and center of tumors, finding distinct gene expression patterns that can predict clinical outcomes and response to therapy. These findings hold promise for improving treatment strategies across various cancer types.
Researchers found that tumour cells escape immunotherapy by losing or changing BCMA and GPRC5D targets on their surface. This understanding has led to the suggestion of periodically profiling myeloma cells throughout a patient's treatment course to adapt treatment strategies.
The Antihydrogen Laser Physics Apparatus (ALPHA) collaboration has measured gravity's effect on antimatter for the first time, confirming it falls downwards. This breakthrough could help explain the universe's lack of antimatter.
A new study published in Pediatrics suggests that pediatric concussions do not impact intelligence or IQ levels. The research, which combined data from two cohort studies in Canada and the US, found no significant difference in IQ scores between children with concussion and those with orthopedic injuries.
Researchers at UCalgary have found that Leishmania parasites exploit immune cells by targeting receptors to gain access and resist elimination, leading to stalled apoptosis and hindered vaccination efforts.
The Hotchkiss Brain Institute will recruit and train emerging neuroscience research leaders to improve brain and mental health globally. Dr. Deepika Dogra's innovative method screens anti-seizure drugs for children using cerebral organoids.
A UCalgary study found that a healthy gut microbiome can prevent deadly hospital infections in critically ill patients. The research showed that the gut microbiota and immune system work together to fight infection, with abnormal gut bacteria increasing the risk of severe infections.
A recent study found that moderate exercise duration (≥150 minutes/week) improves gut microbiome richness and diversity, with no significant impact from exercise intensity. Additionally, normal-weight individuals showed the most beneficial changes, while overweight individuals' microbiomes were influenced by poor dietary habits.
A study led by the University of Calgary found a 22% increase in children and adolescents seeking emergency department care for suicide attempts and an 8% increase for suicidal ideation during the pandemic. This trend contradicts the overall decrease in pediatric ER visits, highlighting the need for mental health resources and services.
A randomized controlled trial of MOXIE shows a significant reduction in clinical outcomes, including hospitalizations and all-cause mortality. The intervention improved patient engagement and behavior change, leading to better health outcomes for seniors at elevated risk of cardiovascular events.
Researchers have designed a novel imaging and experimental preparation system to record the activity of the enteric nervous system in mice, providing new insights into the complex processes of digestion and waste elimination. The findings suggest that physical distention of the gut controls how the entire neural network is coordinated.
A UCalgary study has found a significant link between the diversity of fungal species in an infant's gut and their body mass index (BMI) in early childhood. The research also identified other contributing factors, including maternal diet and exposure to antibiotics, as influencing BMI.
Researchers at the University of Calgary discovered a reduction in brain function's brake signal contributes to decisions about eating in obese mice. The study found that when this region is disabled, lean mice continue to overeat despite feeling full.
Researchers from UCalgary and the World Health Organization found that people with hybrid immunity have the highest level of protection against severe illness and reinfection, offering a key finding for public policy makers. The study suggests vaccination should be prioritized even among those who have had COVID-19.
Researchers discovered that viral infections like SARS-CoV-2 and influenza destroy a natural immunity needed to resist fungal infections. This leads to impaired cooperation between white blood cells, allowing fungi to take root. The study reveals potential repurposing of current therapies to replace damaged antibodies.
Researchers at UCalgary have discovered a potential new treatment for fibrosis, a condition that causes thickening of the gut wall and life-threatening blockage in people with Crohn's disease and ulcerative colitis. The study suggests that drugs targeting specific sensors may prevent inflammation-associated gut blockage.
Researchers at the University of Calgary found that vaccination against influenza significantly lowers the risk of stroke among adults. The study analyzed health records of over four million Albertans and showed that the risk of stroke was reduced in all age groups, not just those at high risk.
Researchers from the Bajo Laberinto Archaeological Project have used lidar technology to uncover a vast, complex urban sprawl beneath the Calakmul forest canopy. The study reveals dense apartment-style residential compounds, numerous temples and shrines, and extensive water management features.
A Canadian study found that swift action to test for and mitigate radon gas reduces lifetime lung cancer risk by as much as 40%. Socio-economic factors, including economic barriers, contribute to delayed detection and mitigation of high radon levels.
Researchers at UCalgary have shown that the antibiotic D-Cycloserine (DCS) increases the effectiveness of transcranial magnetic stimulation (TMS) for people with major depressive disorder. The combination treatment showed significant benefits, including improved depressive symptoms and anxiety levels.
Researchers at the Snyder Institute have identified a promising new approach to treating bacterial skin infections, revealing that monocytes play a crucial role in wound healing. The study highlights the importance of metabolic hormones like ghrelin and leptin in regulating blood vessel growth and tissue repair.
A study of 1,884 children with COVID-19 found that nearly 6% developed long COVID 90 days later, with age 14 and four or more initial symptoms being key factors. The study suggests the need for guidance and follow-up for high-risk children.
A new study published in Scientific Reports found that astronauts who spent six months in space experienced significant bone loss upon their return to Earth, with weight-bearing bones only partially recovering. The researchers discovered that the bone loss was comparable to decades of age-related bone loss on Earth.
Researchers with the Calgary Stroke Program have made a breakthrough in treating acute ischemic stroke with Tenectepele, a safe and well-tolerated drug that can be administered as a single dose. The study shows that TNK works better than current recommended drug tPA, restoring blood flow faster and for a longer period.
Researchers at University of Calgary have identified a molecule in the nervous system that enhances sensitivity to pain, potentially treating chronic pain with existing anti-cancer drugs. The discovery could offer an alternative to opioid-based pain medication, which can lead to tolerance and addiction.
A randomized clinical trial found that a specific probiotic supplement accelerated the maturation of the microbiome in extremely preterm infants, leading to reduced intestinal inflammation and improved feeding tolerance. The study also showed potential benefits for reducing the risk of food allergies in these vulnerable infants.
Researchers have identified a new oxygen sensing mechanism in spinal cord neurons capable of triggering activation of the sympathetic and respiratory nervous system. This discovery suggests that SOS are critical for autoresuscitative reflexes and contribute to physiological regulation in health and disease.
A University of Calgary study found that hydroxychloroquine slows worsening of disability in people with primary progressive multiple sclerosis. The experimental trial involved 35 participants and showed promising results for the generic drug.
A new international study analyzed over 10,300 children with COVID-19, finding that older age, pre-existing chronic conditions, and symptom duration were significant risk factors for severe outcomes. The study also revealed that healthy-looking children rarely deteriorated significantly after initial hospital visits.
A Canadian research team has found that new homes in Canada have significantly higher radon gas levels than those in Sweden. The study, which analyzed over 25,000 Canadian and 38,000 Swedish properties, suggests that without intervention, radon levels in Canadian homes will increase by another 25% by 2050.
A UCalgary study found that the steroid dexamethasone alters immune cell function in a sex-dependent manner, benefiting male patients but providing little to no benefit for females. The researchers' findings suggest that current treatments may only be effective for half the population.
University of Calgary researchers have discovered specific microbial factors that help regulate the enteric nervous system, which controls the gastrointestinal tract. This finding may lead to novel ways to treat gastrointestinal disorders such as irritable bowel syndrome and inflammatory bowel disease.
A study led by Dr. Satish Raj is investigating individuals with autonomic problems after recovering from COVID-19, finding common disorders such as orthostatic hypotension and postural orthostatic tachycardia syndrome. Researchers aim to find viable treatments for debilitating symptoms affecting daily life.
A new study found that depression and anxiety symptoms have doubled in children and adolescents globally during the pandemic. The study recommends prioritizing recovery planning now to mitigate sustained mental health effects.
A coalition of scientists analyzed satellite imagery and seismic records to understand the cause of the Uttarakhand disaster, finding that climate change is contributing to its frequency. The study suggests that a giant landslide triggered a devastating debris flow, destroying hydropower facilities and killing hundreds.
Researchers at UCalgary have found that even low levels of Bisphenol A (BPA) exposure during pregnancy can impact brain development in mice, affecting circadian rhythms and behavior. The study adds to growing evidence on the harms of BPA and highlights the need for stricter safety guidelines.
Researchers have identified a genetic risk gene relevant to childhood OCD, which could help improve treatment options and diagnose youth earlier. The study used saliva samples from over 5,000 children and youth, comparing them to participant responses on obsessive-compulsive traits.
Researchers at University of Calgary and University of Bern discovered that macrophages, a type of white blood cell, rush to surgical sites and cause excess scarring. Two methods to inhibit this natural response were found: removing macrophages or introducing a drug to block their stickiness.
Researchers at UCalgary and Swiss institutions discovered a new method to regulate blood pressure in people with spinal cord injuries using targeted epidural electrical stimulation. The study's findings show that this technique can stabilize hemodynamics, allowing vital organs to maintain an appropriate supply of blood without medication.
Researchers have identified seven DNA fingerprints that define cancer risk, including a protective germline pattern and six that present a higher risk. The discovery refines the long-held view that lifestyle factors contribute to cancer risk and sheds light on the role of genetics in cancer development.
Researchers at UCalgary's Clark H. Smith Brain Tumour Centre have made a breakthrough in combating glioblastoma by reprogramming the immune system to fight cancer instead of fueling it. By disrupting interleukin 33, a substance that recruits immune cells to tumours, survival rates increased from two months or less to over a year.
Researchers at the University of Calgary have discovered a way to record real-time images of immune cells inside the lungs, revealing that these 'cleaners' become paralyzed during infections. This new imaging technique has provided crucial insights into the immune system's response to deadly bacteria and viruses like flu and COVID-19.
Researchers at UCalgary have made significant breakthroughs in understanding how skin heals after severe burns, identifying a population of progenitor cells that can regenerate tissue. By modifying genetic programs and wound environments, the study offers hope for developing drugs to promote true regeneration and prevent scarring.
Researchers have identified specific bacterial species that boost T-cell immunity and improve the effectiveness of immunotherapy in treating certain cancers. The discovery may lead to new treatments by harnessing the power of the microbiome to target cancer cells.