Researchers developed nanoTCEs to target AML cells, showing high specificity and potency in treating the disease. The technology uses nanoparticles to bind to CD33, a marker present on AML cells.
A new test can determine the presence of SARS-CoV-2 neutralising antibodies within 10 minutes, allowing for larger-scale screening and mass monitoring. The rapid cellulose pull-down viral neutralisation test has been developed using protein engineering technology and offers quick results with high accuracy.
Researchers at Rice University developed a method to decontaminate disposable surgical masks by heating them to 70 degrees Celsius, eliminating 99.9% of the SARS-CoV-2 virus and preserving mask material. The study provides promise for adapting this protocol to future outbreaks.
Researchers at UNSW have developed liquid metal enabled continuous flow reactors that can produce materials with tuneable system performance and controlled material quality. The systems rely on surface tension to pump fluids, eliminating the need for mechanical parts.
A study of over 1,100 prostate cancer patients found that androgen deprivation therapy did not increase the risk of death within 30 days after a COVID-19 infection. Researchers concluded that men receiving androgen deprivation therapy had similar mortality rates as those who did not receive this treatment.
Researchers designed a novel polymer to bind and strengthen silica sand for binder jet additive manufacturing, creating structures with intricate geometries and exceptional strength. The study demonstrates a 300-times-weight limit for a 3D-printed sand bridge.
A UT Dallas-led team of researchers has developed a new technique to deliver medication to the brain by temporarily opening the blood-brain barrier. The method uses light and nanoparticles to pry open tight junctions, allowing medication to reach its target with minimal disruption.
The study compared traditional mining and innovative synthesis methods for producing a single carat diamond, revealing that energy consumption varies widely between the two. While some synthetic methods are more efficient than mining, others consume significantly more energy.
Researchers discovered that retinal pigment epithelium cells release exosomes containing normal proteins and those associated with drusen, a key AMD manifestation. This finding may lead to early diagnosis through biomarker detection in blood, tears, or saliva, potentially treating millions of Americans before geographic atrophy onset.
The UK Space Agency has awarded £650,000 to Northumbria University to develop a commercially available laser-based inter-satellite communications system. The new technology promises to transform the satellite communications industry by transmitting data 1,000 times faster and more securely.
A NJIT-led team has received a $1.25 million grant to identify and eliminate barriers for women scholars in technology commercialization on university campuses. The team aims to increase diversity in STEM faculty researchers and entrepreneurs, particularly women and underrepresented groups.
As investors increasingly demand climate-friendly stocks, researchers call for a global framework for mandatory climate risk disclosure by companies. A hybrid governance model that balances shareholder rights with blockholder interests is necessary to address the pressing need for a timely transition to net-zero business principles.
Researchers at FRIB are studying gentle nuclear reactions with fragile nuclei to improve physics models, which can deepen our understanding of the universe. This knowledge can also lead to better medicine, such as more precise cancer treatments.
Research suggests that obesity triggers inflammation, leading to an increase in myeloid-derived suppressor cells, which break down bone tissue. This can result in gum disease and tooth loss. The study found a significant link between high-fat diets and increased osteoclasts and alveolar bone destruction.
In a large commercially insured population, overall outpatient care usage didn't change significantly despite increased telemedicine use. Telemedicine appeared to substitute for in-person visits, suggesting its potential as a convenient alternative.
Researchers at Okayama University used CRISPR/Cas9 technology to genetically edit barley, creating mutants that resist pre-harvest sprouting and can be promoted with cold temperatures or hydrogen peroxide treatment. This breakthrough has significant implications for high-quality barley production and could lead to improved beer quality.
New research from Oregon State University found that climate change is altering ocean conditions, creating new environments that could undermine conservation goals in the world's largest marine protected areas. By 2060, most of these changes will occur, including warming and acidification levels.
Researchers proposed rational design of nanocatalysts using metal-support interaction descriptor, identifying optimal balance between adhesion and cohesion energies. This theory guides the design of ultrastable heterogeneous metal nanocatalysts, overcoming sintering issues and improving productivity.
A peer-reviewed study published in Life journal proves Reflex identifies biomarkers for concussions, enabling accurate clinical diagnosis and decision-making. The study, conducted by Purdue University, uses pupillary light reflex to measure concussion patients' recovery and prevent compounding injuries.
This study found high expression of Myosin 1g in pediatric acute lymphoblastic leukemia, suggesting its potential role in disease pathogenesis, particularly in high-risk patients. The research also showed that Myo1g may serve as a biomarker for identifying patients with an increased risk of relapse.
A study by the University of Surrey and Heathrow Airport found that airport operators are staying on track to reduce carbon emissions, but face challenges in implementing their plans. The majority reported seeking support from governments to stimulate the development of sustainable aviation systems.
Researchers identified a significant vascular defect in patients with moderately severe Parkinson's disease, which may explain earlier study findings and provide a new target for therapeutic intervention. The discovery highlights the blood-brain barrier's crucial role in neurodegenerative diseases like Parkinson's.
A new study found that most personal protective equipment (PPE) masks are not designed for Black And Minority Ethnic (BAME) backgrounds and women, leading to inadequate protection. The research highlights the need for further studies on PPE development to account for differences in facial dimensions across gender and ethnicity.
Researchers successfully manipulated a single molecule into an upright position and measured its stability, gaining insights towards fabricating electrical components and circuits at the atomic level. The findings have potential applications in creating ultrasensitive sensors, quantum dots, and quantum computers.
Research reveals universal characteristics and mechanisms of long-lived eastward propagating MCSs, including coupling with plateau vortex and shortwave trough. The study improves understanding of rainstorms in Tibetan Plateau and Yangtze-Huai River Basin.
A new study reveals that 90% of COVID-19 patient rooms have detectable coronavirus on at least one surface, with the virus persisting days later on TV remote controls and nurse call buttons. Regular cleaning is crucial to prevent spread among vulnerable populations.
Simulations show that a migrating planet can produce patterns matching those observed in disks, explaining why planets are rarely found near outer rings. The findings also help to confirm the planet theory for ring formation.
Research suggests that iron is a key factor in aging, causing cellular damage and organ deterioration. By blocking iron absorption, people may be able to extend their lifespan.
PKU researchers harness higher order protein catenation to create complexed topological proteins, leading to the synthesis of artificial antibodies with enhanced affinity and prolonged serum half-life. The study successfully expands toolkits for protein entangling motifs, promoting advanced protein therapeutics.
A new tool, Diversity for Restoration (D4R), helps nations tailor tree species selection to local environmental conditions and objectives. This is crucial for successful landscape restoration projects that benefit biodiversity, food security, and livelihoods while drawing carbon out of the atmosphere.
Aspen recovery in Yellowstone National Park has been found to be less robust than previously believed due to biased sampling methods. Random sampling of all young aspen within a stand revealed a slower rate of recovery compared to the five tallest young aspen, which were used in previous studies.
A single-cell chromatin atlas for the human genome reveals how genes are turned on or off in different cells, a major step toward understanding the connections between genetics and disease. The findings identify disease-trait-relevant cell types for 240 multi-genic traits and diseases.
A University of Wollongong team has combined two doping elements to achieve new efficiencies in the topological insulator Bi2Se3. The resulting crystals show clear ferromagnetic ordering, a large band gap, high electronic mobility, and the opening of a surface state gap.
University of Calgary researchers have discovered specific microbial factors that help regulate the enteric nervous system, which controls the gastrointestinal tract. This finding may lead to novel ways to treat gastrointestinal disorders such as irritable bowel syndrome and inflammatory bowel disease.
Researchers at Dalian Institute of Chemical Physics observed the Marcus inverted region in charge transfer from low-dimensional semiconductor materials. This finding reveals a new understanding of the fundamental energetics dependence of electron transfer, benefiting energy conversion applications of these materials.
A new study led by University of Minnesota Medical School researcher Xavier Revelo found that macrophages play a role in protecting the heart after injury. The research team discovered a large increase in cardiac macrophages early in response to a cardiac injury similar to high blood pressure.
A study analyzing data from 109 COVID-19 patients found that obesity is the key factor associated with endothelial dysfunction, a condition increasing heart attack and stroke risk. The results suggest an 17% higher cardiovascular risk for obese patients compared to those of normal weight.
A study by University of Wisconsin-Madison researchers identified key proteins in fungal biofilms that control resistance to antifungal drugs and dispersal throughout the body. These proteins provide potential drug targets to impair a pathogen's antimicrobial defenses, including the fungus Candida albicans.
Researchers developed a molecular compound that serves as a low-cost electrolyte for redox flow batteries, enabling stable operation and high capacity retention. The compound overcomes limitations of previous electrolytes by increasing its hydrophilicity and conductivity.
Amazon Rainforest birds have reduced body mass by an average of 2% every decade since the 1980s, with most species losing about 27.6 grams on average. The birds' bodies and wings have also changed to become more energy-efficient in flight, with longer wings and lighter bodies adapted to hotter and drier conditions.
Researchers at Peking University developed a non-invasive exhaled breath screening system for COVID-19, identifying key breath-borne VOC biomarkers in just 5-10 minutes. The technology reduces transmission risk by providing quick screenings for false negatives and hospital discharges.
Research by Assistant Professor Yue Liao found that cancer survivors improved their physical functioning and quality of life after participating in a 12-week group-based exercise program. The study focused on minority and medically underserved cancer survivors who often lack access to physical activity resources.
Borophene, a 2D version of boron, can be synthesized on hexagonal boron nitride using weak van der Waals forces. This method allows for easier removal and evaluation of the material for its plasmonic and photonic properties, as well as its electronic properties relevant to superconductivity.
A noninvasive diagnostic method, sonobiopsy, has been developed to detect brain tumors with improved sensitivity. The method uses focused ultrasound to target tumors and injects microbubbles that release biomarkers into the bloodstream.
A new article reviews key concepts, mathematical models, and statistical techniques for testing rationality in animal behavior. The authors tackle five significant obstacles to justify conclusions from empirical testing of transitivity, including aggregation artifacts and scientific parsimony.
A new CIRES-led study reveals that ocean temperatures, not ice sheets, are responsible for the dramatic shift in atmospheric circulation and precipitation patterns on the West Coast. The research uses a climate model to evaluate the impact of Northern Hemisphere ice sheets on West Coast dynamics during the Last Glacial Maximum.
The BESIII experiment analyzes threshold data to study weak decays of charmed hadrons, measuring physical observables and extracting strong phases. High-precision tests of the Standard Model are performed, including determinations of CKM matrix elements and lepton universality.
A research team discovered a quantum confinement effect in a 3D-ordered macroporous structure of BiVO4, enabling hydrogen production under visible light. The study found that the 3DOM structure had higher photocatalysis efficiency and produced more oxygen than its plate-like counterpart.
Researchers found that green tea catechins EGCG and ECG enhance fitness and lifespan in C. elegans by inhibiting complex I activity, reducing fat content and enhancing antioxidant defenses. This study provides evidence for the potential health benefits of green tea consumption in extending human lifespan.
Integrating food production and biodiversity conservation in spatial planning can minimize trade-offs between nature and people. The study found that joint planning processes for rural development and biodiversity conservation are more ecologically effective and socioeconomically feasible than separate strategies. By dedicating at leas...
Researchers found that blood stem cells, which are among the smallest cells in the body, lose their ability to perform their normal function — replenishing the body’s blood cells — as they grow larger. However, when the cells were restored to their usual size, they behaved normally again.
A new study reveals that female physician-parents were more likely to experience disruption to their home and work lives, and suffered from higher rates of depression and anxiety compared to male counterparts. The study also found that motherhood contributed to a significant increase in depression symptoms over time.
Researchers have genetically engineered bacteria to detect specific chemicals in the gut, which can help maintain balanced neurotransmitter levels. The bacteria, called Escherichia coli Nissle 1917, produce enzymes that degrade or synthesize target chemicals, potentially alleviating mental health issues.
A recent study led by Okayama University scientists found that metformin activates a subset of immune cells called CD8+ T-lymphocytes to attack and kill tumor cells. The study revealed that metformin increases the production of reactive oxygen species in these cells, which activates growth pathways and allows for proliferation.
Restoring 47.5 million hectares by 2030 demands high-quality seeds and seedlings. The study highlights the need for effective seed control and local community participation to ensure successful restoration projects.
Researchers found that specifying a shorter deadline increases response rates, while long deadlines allow people to procrastinate and forget. No deadline led to the most responses, suggesting that removing urgency leads to inaction.
Researchers at CNIC have identified the essential role of GPR126 in placental development, revealing its critical function in fetal growth and viability. The study also highlights a possible link between GPR126 dysfunction and pregnancy complications such as preeclampsia.
Researchers at Kyoto University developed a new neural-optic system to manipulate memories by inhibiting key proteins. This technique can help isolate memory formation and potentially lead to treatments for mental disorders like Alzheimer's disease and schizophrenia.
Researchers from the University of Copenhagen have discovered that naturally acquired immunity to malaria works differently than immunity following vaccination. The immune system uses natural killer cells to fight the parasite, which is more tailored to the disease than other typical infections.
A recent study analyzed over 18,000 reported adverse events from patients taking various anti-obesity medications. The study found that 4.9% of reported events were fatal, with 35% requiring hospitalization. Further research and monitoring are needed to address the safety concerns surrounding these medications.
A new study by Columbia University Mailman School of Public Health found that NYC COVID-19 mandates enforcement mirrored the discretionary nature of the New York stop-and-frisk program, resulting in racialized criminalization and punishment. The use of police to enforce public health mandates increased the risk of COVID spread due to f...
A novel method was proposed to effectively control the structure of colloidal molecules through a one-pot synthesis route. This approach enables the preparation of colloidal molecules with various morphologies, including popcorn-like and CO2-like shapes, by manipulating the addition order and content of styrene and divinylbenzene.
The Stanford Computational Imaging Lab has developed a technique to reduce speckling distortion in holographic displays, while another paper proposes a method to realistically represent the physics of 3D scenes. The new system uses neural networks and camera-in-the-loop calibration for real-time adjustments.
A recent study found that digital health programs and apps are less effective in boosting physical activity among users with lower socio-economic status. Researchers analyzed over 14,000 studies and concluded that these interventions do not provide clear benefits for individuals from disadvantaged backgrounds.
Opioid overdose deaths in Illinois increased significantly from July 2017 to June 2020, with the highest rates occurring in 2020. The study analyzed data from the Centers for Disease Control and Prevention and found a notable spike in unintentional opioid overdose deaths during the pandemic.
Researchers at Lancaster University examine the use of AI in the food sector, highlighting the need for trusted data collaboration to reduce waste and increase sustainability. They also warn about potential ethical issues and unexpected consequences of new technology.
A team of researchers has developed a digital tool to better monitor Barrett's esophagus, which affects over 3 million people in the US. The tool, based on a computational model of the human esophagus, aims to minimize invasiveness and reduce deaths from esophageal cancer.
Researchers create a novel concept to improve supercontinuum light sources by incorporating nano-films into microstructured fibers. This results in broad and flattened output spectra with low input energy, ideal for applications like optical coherence tomography and field hand-held spectroscopy.
Researchers discovered that inhibiting a specific signaling pathway can prevent immunotherapy resistance in ovarian cancer, leading to improved tumor responses. This breakthrough has significant clinical implications and will inform a new clinical trial to test the efficacy of this approach.
The study provides insights into the genetic evolution and migration of chickpeas, offering a roadmap for improving the crop's nutritional value and climate resilience. Chickpeas are a main protein source for hundreds of millions of people worldwide, particularly in South Asia, Africa, and other parts of the world.
A multi-center study assesses medicinal mushrooms and Chinese herbs for therapeutic benefit in treating acute COVID-19 infection. The MACH-19 trial evaluates the safety and feasibility of two investigational compounds, one in capsule form and another as a Chinese herbal formula.
Studies using virtual reality environments revealed that individuals with anxiety disorders exhibited increased brain activity in response to perceived threats, even in safe areas. The findings highlight the need for personalized treatments that help patients regain control over their body.
Researchers predict that targeted transport measures in Cairo will reduce health-damaging pollutants by up to 55% and global warming emissions by an average of 12.4%. Better vehicle inspection and maintenance, as well as improved public transport infrastructure, are key strategies identified in the study.
Researchers from the University of Rochester have further evidence that genes are evolving defensive mechanisms to counteract harmful genetic elements. The study found that specific genes developed weapons-like structures to combat 'parasites' in the human genome, highlighting the ongoing 'arms race' between these two forces.
Researchers used DNA analysis to confirm traditional Tsleil-Waututh Nation fishing practices that promoted sustainable management and conservation. These practices, which selectively harvested male salmon, allowed for larger harvests while maintaining healthy populations and successful spawning.
Research at Uppsala University found a correlation between specific genes and prognosis in Chinese patients with cardia cancer. Focal amplification of the ERBB2 gene was linked to better prognosis, while EGFR amplification had worse outcomes.
A study published in Cardiovascular Research found that an anticoagulant medication can improve the survival of COVID-19 patients and shorten the duration of active SARS-CoV-2 infection. The medication, low-molecular-weight heparin, also curtails viral persistence by inhibiting the virus's ability to bind to cells.
Researchers have used advanced microscopy to study the ultrastructure of huntingtin inclusions, revealing different mechanisms of aggregation that lead to distinct biochemical properties. The findings suggest targeting inclusion growth as a potential therapeutic strategy for slowing Huntington's disease progression.
Researchers at Virginia Tech uncover two types of microorganisms that produce amorphous carbon, a form of elemental carbon thought to be formed under extreme conditions. This discovery challenges existing knowledge and raises questions about its impact on the Earth's carbon cycle.
A new study in India reveals that more than half of surveyed crop varieties are under threat of extinction, with 50% considered threatened across five different agroecological regions. The Varietal Threat Index methodology proposes a systematic way to monitor changes in varietal diversity on farms.
Researchers at Ruhr-University Bochum study coral reefs' reaction to climate change, discovering polyp bailout as a potential survival mechanism. The study reveals different species react with varying intensity to environmental stressors, and that individual polyps can survive and grow in new locations.
Researchers have developed a new synthetic molecule that recruits immune cells to fight cancer. The treatment shows promising results in mouse models of breast and pancreatic cancer, with some animals cured after just a few injections.