Researchers found that different animal species, including humans, mice, giraffes, and tigers, accumulate similar numbers of genetic changes over their lifetime. The study supports the theory that somatic mutations play a role in ageing, with longer lifespan species experiencing slower mutation rates.
Researchers at Hefei Institutes of Physical Science found nintedanib inhibits GIST cell proliferation through KIT signaling pathway. Nintedanib also overcomes resistance caused by extracellular signal-regulated kinase reactivation and upregulation of fibroblast growth factor activity.
New research reveals that women with strokes often exhibit generalized symptoms such as confusion and weakness, potentially leading to delayed diagnoses. Women also face worse post-stroke outcomes, including increased institutionalization rates, compared to men.
Researchers at Charité, MDC, and FU Berlin have studied the mechanisms of action of antibody and dexamethasone treatments for COVID-19. They found that combination therapy is more effective in reducing viral activity and inflammation in lung tissue, suggesting a potential game-changer in treating severe cases.
A five-year, $13 million grant will investigate the molecular and cellular mechanisms of prion transmission in CWD. The researchers aim to understand the inter-species transmission potential of the disease and its ability to spread from animals to humans.
Researchers have found that treating prostate cancer cells with novel CDK8 and CDK19 inhibitors reduces their potential to migrate into surrounding structures. This suggests a promising approach to overcome resistance against anti-androgenic therapy, offering new therapeutic options for patients with advanced disease.
Researchers at Rutgers University found disparities in palliative care and hospice referrals among minority patient groups, highlighting the need for standardized policies to improve access. The studies revealed that language barriers, economic status, and cultural differences contribute to these gaps in care.
Forewarning messages and annotations effectively raised study participants' awareness of potential bias in political news articles. The study found that visualizations can communicate bias, improving media bias awareness.
A new report estimates the total economic burden of multiple sclerosis (MS) in the United States to be over $85 billion, with direct medical costs reaching $63.3 billion and indirect non-medical costs totaling $22.1 billion. The average excess medical cost per person with MS was found to be $65,612.
A study of nearly a million adults in England found that those at risk of heart attack or stroke over the next 10 years are substantially more likely to become seriously unwell with COVID-19. People with elevated cardiovascular risk were six times as likely to die from COVID-19 and had three times the risk of hospitalization, according...
The 2022 APS Annual Convention will feature leading researchers on various aspects of human behavior, including substance abuse and mental health. Complimentary registration is available for working journalists to cover the convention.
A new cell therapy has shown promising results in slowing the progression of Duchenne muscular dystrophy, a rare genetic disorder. The treatment uses heart cells to improve skeletal muscle and heart function, offering a potential cure for advanced disease cases.
A study found that mothers in a 19th century Dutch village had low rates of breastfeeding, likely due to their busy work schedules and easy access to cow's milk. Researchers analyzed the remains of 277 individuals and found little evidence of breastfeeding, surprising given the community's cultural associations with breastfeeding.
Researchers have developed a new method to recover muscle mass in aged mice by injecting pericyte-derived extracellular vesicles into the muscles after disuse. This approach has shown promise in recovering skeletal muscle fiber size and remodeling the extracellular matrix, which supports muscle structure and growth.
A study from EPFL and the University of Lausanne developed a method to calculate which jobs are at risk of being automated by robots. The team created an algorithm that predicts the risk of automation for hundreds of jobs and suggests alternative careers with minimal retraining requirements.
Researchers found that alterations in gut microbiota can help treat pancreatic and hormonal dysfunction in diabetes patients. The study showed that antibiotics treatment can improve insulin sensitivity and reduce glucose intolerance in obese mice and humans.
A speed-of-light internet project aims to reduce network latency by routing data through the US, responding 10-100 times faster than current networks. If deployed, it could give 85% of Americans near-real time connectivity, revolutionizing online experiences.
Astronomers identify GNz7q, a dusty compact object with properties of both galaxies and quasars, born 750 million years after Big Bang. The discovery provides new insights into the rapid growth of supermassive black holes in early universe.
A study by University of Waterloo researchers identified areas such as player fatigue, mental stress, and peak performance conditions that require in-depth research to improve coaching and player performance. Professional esports players often practice for 12-14 hours a day, six days a week, leading to burnout and physical injuries.
A study by the University of Cincinnati suggests that transgender and gender diverse people can benefit from better-designed smartphone apps offering voice and communication training software. The app features identified as most critical include feedback, accountability, automated goal setting, and non-interactive elements like videos ...
Astronomers have identified a rapidly growing black hole in the early universe, GNz7q, which is considered a crucial 'missing link' between young star-forming galaxies and the first supermassive black holes. The team used Hubble data to determine that GNz7q existed just 750 million years after the big bang, with properties consistent w...
A new survey study finds that COVID-19 may have amplified prejudicial attitudes towards ethno-racial minorities in the US workforce. The study, published in PLOS ONE, suggests that workplace discrimination can exacerbate prejudice and have long-term impacts on minority groups.
Researchers found that human embryos express a vast variety of alternative mRNAs when they are just 8 cells old, leading to a temporary collapse of splicing regulation at the zygotic genome activation stage. This phenomenon is developmentally programmed and occurs because it is necessary for functional reasons, ultimately affecting DNA...
A new UC San Francisco study found that nearly half of young adults had mental health symptoms during the pandemic, with many unable to access therapy. The study highlights the importance of addressing barriers to care, including cost, stigma, and confidentiality concerns.
New research at Aston University found that pre-school children's emotional eating is influenced by their innate food drive and mothers' eating habits. The study suggests that parenting practices, such as using food as a reward or restriction, can contribute to emotional eating in young children.
Researchers at Stevens Institute of Technology are pushing through technical barriers in organ printing by leveraging decades-old technique and computational modeling. The team aims to create any type of organ at any time, including skin on an open wound, using microfluidic bio-printing.
Research finds that historically redlined neighborhoods are burdened by excess oil and gas wells, leading to increased air and water pollution, noise, and stress. The study reveals a link between these exposure disparities and persistent social inequities in community environmental health.
The Paul Scherrer Institute and Italian Institute of Technology have developed a novel substance called Todalam that disables tubulin, a protein essential for cell division. In cell cultures, Todalam kills cells, making it a promising starting point for developing an anti-cancer drug.
Researchers develop experimental platform to study mini-magnetospheres, observing effects of magnetic field on magnetopause and bow shocks. The platform combines Large Plasma Device with lasers and magnetic dipoles, allowing for controlled variation of parameters.
Researchers at Florida Atlantic University found that increasing sun exposure in rehabilitation facilities can enhance health and recovery in green sea turtles with fibropapillomatosis. Vitamin D levels increased significantly in turtles exposed to higher UV light, leading to less tumor regrowth and improved overall health.
Researchers at TU Wien have developed a new approach to produce artificial tissue using micro-scaffolds with a diameter of less than a third of a millimetre. These scaffolds can accommodate thousands of cells and enable high cell density and control over mechanical properties.
Researchers tracked 60 stingrays for a year, finding they prefer shallow waters but move into deeper lagoons during extreme tides and temperatures. Climate change may alter their preferred habitat, putting them at risk from sharks.
A new study models the probability of renewable energy droughts in Texas, finding that grid operators may need backup energy sources due to variable wind and solar production. Researchers suggest increasing capacity or exploring alternative storage methods to avoid extended dry spells.
A team of researchers from Nanyang Technological University and National Parks Board in Singapore has discovered that certain tropical plant species can absorb and remove toxic heavy metals and metalloids from contaminated soil. The study identified 12 plant species effective for phytoremediation, including Cow Grass, Brake Fern, and I...
Research suggests top reviews are a key factor in consumer purchasing decisions when comparing products. The study found that concrete details in reviews can sway consumers, and businesses should focus on responding to negative reviews rather than gaming the rating system.
A new approach called REFERS enables automatic acquisition of supervision signals from hundreds of thousands of radiology reports, achieving high accuracy in predictions. The innovative method reduces human cost by 90% and surpasses conventional medical image diagnosis employing AI algorithms.
The National Institute for Materials Science has developed an oxidation-resistant copper core–nickel shell ink, significantly improving resistance to degradation. This cheaper and more stable ink may popularize printed electronics, offering comparable conductivity to conventional metallic inks.
The QUT Centre of Materials Science has published a special journal issue showcasing its research on innovative materials. The centre's work covers various themes including polymeric materials, energy materials, biomaterials, and nanomaterials, with a focus on fundamental understanding and real-world applications.
Researchers from Trinity College Dublin have discovered how SARS and MERS coronaviruses block the induction of antiviral proteins, preventing a strong immune response. This finding has potential implications for developing new therapeutic options to treat COVID-19 and future deadly coronaviruses.
Researchers propose a modular Mars exploration rover system consisting of four two-wheeled robots that can operate independently or combine in various constellations. The approach enables longer missions and gathers more information about the planet's history and potential habitability.
A new nationally representative study found that two in five adults with attention deficit hyperactivity disorder (ADHD) were in excellent mental health. Being married, physically active, free from chronic pain, and having no history of depression or anxiety were associated with complete mental well-being.
An international team of engineers has successfully bioprinted bone along with two growth factor encoding genes that help incorporate cells and heal defects in rats. The researchers used gene encoding PDGF-B and BMP-2, which encouraged cell multiplication and migration, resulting in a 40% increase in bone tissue creation.
Research suggests that pregnant mothers' environments can influence the structure and function of their babies' brains before birth. A study found that babies born to mothers living in poverty tend to have smaller brains than those whose mothers had higher household incomes. Additionally, exposure to crime during pregnancy may affect b...
A study of NASA, ESA, and Russian space agency data found that extended spaceflight leads to changes in the brain's perivascular spaces. The research, led by Medical University of South Carolina scientists, used MRI scans to evaluate brain changes before and after six months on the International Space Station.
A 80-mile wide comet, one of the oldest objects in the solar system, is heading towards Earth at 22,000 miles per hour. The comet's massive nucleus, 50 times larger than most known comets, will pass within 1 billion miles of the sun in 2031.
Researchers at Penn State and UC San Diego found a new method to tune the magnetic properties of manganese bismuth telluride, enabling efficient control of lossless electrical currents. The discovery uses phonons to modify the magnetic bonding between layers, potentially leading to ultra-fast devices with reduced energy waste.
Researchers at Pohang University of Science & Technology have discovered a way to enhance the surface adhesion of mussel adhesive proteins (MAPs) by converting oxidized Dopa into a stronger form called △Dopa. This breakthrough enables MAPs to maintain strong underwater adhesion, paving the way for potential biomedical applications.
Research shows austerity measures reversed gains made in reducing waiting time inequality for socioeconomically deprived patients in Scotland. Waiting times increased across all patients after the introduction of austerity measures in 2010.
Researchers have identified a biomarker that indicates high risk of impending stroke post-subarachnoid hemorrhage, enabling early treatment initiation in comatose patients. Electrodiagnostic monitoring detects 'spreading depolarizations' caused by toxic by-products of blood breakdown, allowing clinicians to intervene before it's too late.
Adolescent drug overdose deaths nearly doubled in 2020 and rose another 20% in early 2021 compared to the 10 years prior, despite stable drug use rates. The increase is largely attributed to illicit fentanyls found in counterfeit pills, which can be deadly if ingested.
Researchers developed an organic anti-ambipolar transistor capable of performing five different types of two-input logic gates at room temperature. This breakthrough could lead to the creation of high-performance mobile devices and electrically reconfigurable logic circuits.
A recent study of 280 mother-infant pairs found that prenatal exposure to social disadvantage and psychosocial stress was associated with reduced infant brain volumes at birth. The researchers used magnetic resonance imaging (MRI) to measure the brain volumes of the infants at birth.
A team of researchers from Kobe and Kyoto universities proposes an ethical framework for conducting research on conscious brain organoids. The framework assumes that brain organoids already possess consciousness and recommends guidelines similar to those for animal experiments. Key considerations include minimizing the number of organo...
A project aims to develop software toolkits to assess neural network robustness and potential security vulnerabilities. The goal is to create a framework for building secure AI systems, emphasizing human expertise in data collection and testing.
Researchers at the University of Sheffield have identified a unique bacterial phosphatase, PafA, that can efficiently release phosphate from its organic forms. This discovery has potential to help reduce the consumption of phosphate chemical fertilisers and promote sustainable agriculture.
A Rutgers study found that climate change will alter predator-prey interactions, preventing species from adapting to changing conditions. This will lead to a decline in commercially important fisheries and a shift in the abundance of species in their new geographic ranges.
A new carbon dots-based organic blend, m-CDs@CA, was developed to exhibit superior long persistent luminescence (LPL) features. The afterglow is observed for over one hour via irradiation by a hand-hold UV lamp, making it suitable for applications under ambient conditions and in aqueous medium.
Independent sector providers are the least likely to be compliant with national guidelines and standards for online STI test services in the UK. The study found that many providers failed to provide adequate health promotion information, triage, or advice on accessing preventive treatment after exposure to HIV.
Researchers investigate plant-based meat substitutes to identify sensory weak points, finding muscle proteins emulsify fats and oils differently than plant proteins do. The study reveals fundamental differences in molecular structure and mouthfeel between meat and vegan sausages.
Researchers found that Massachusetts' state mandate driving staff acceptance and creating an atypical flexibility to seek innovative solutions. The program showed that medication diversion was uncommon, and protocols helped ensure correct use of the medication by detainees.