Articles tagged with Virus Testing
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The HPV vaccine GARDASIL has been shown to reduce abnormal Pap test results by 43% in women, preventing the development of cell changes that lead to cervical disease. This reduction also translates to fewer invasive procedures like cervical biopsies, with a 42% decrease observed in GARDASIL recipients.
A new TB screening test based on ELISPOT test has shown high sensitivity and specificity in detecting latent TB infection in HIV-infected individuals. The test was compared to the traditional tuberculin skin test (TST) and found to be more sensitive, but its effectiveness in severely immunosuppressed individuals remains unclear.
Researchers at Brown University have created a 10-minute animated video explaining rapid tests for HIV, aiming to educate patients and healthcare providers. The video's effectiveness was tested in pilot trials, showing that it can improve comprehension of rapid HIV testing fundamentals.
Researchers call for GPs to be more proactive in offering HIV testing to higher-risk groups, citing low rates of early diagnosis and serious consequences. The study found that half of surveyed HIV-positive Africans were diagnosed late, despite above-average use of healthcare services.
Research published in PLoS Medicine highlights the high risk of HIV infection among men who have sex with men in developing countries. Targeting HIV prevention programs to reach these men is crucial to curb transmission and reduce global burden.
A new test vaccine against Japanese encephalitis virus has shown promising results, with a high seroconversion rate and good safety profile. The vaccine is considered at least as effective as the existing licensed vaccine, making it a potential candidate for use in travelers and children in endemic areas.
Cases of lymphogranuloma venereum have surged in the UK, primarily affecting men who have sex with men, with many also infected with HIV. Experts are urging caution on new diagnostic tests that require careful validation before widespread use.
A study of 200 consecutive patients found that combining clinical history, ultrasonography, and liver function tests effectively excludes common bile duct stones. The triple test has high sensitivity and specificity for diagnosing CBDS, making it a recommended pre-operative assessment for laparoscopic cholecystectomy.
Researchers at Iowa State University have developed a new technology that can detect a single molecule of the human papillomavirus, associated with cervical cancer, significantly improving current detection methods. This breakthrough allows for earlier diagnosis and potentially increased vaccine effectiveness.
High-risk individuals face barriers to testing, including lack of healthcare access and mental health issues. Despite CDC efforts, only 27% of those at highest risk have been tested in the past year, highlighting untapped potential for increased testing rates.
A new study from McGill University finds that the HPV screening test outperforms the traditional Pap test in detecting pre-cancerous lesions without false negatives. The HPV test achieved an accuracy of 94.6%, while the Pap test only reached 55.4% accuracy, making it a more reliable method for cervical cancer screening.
The American College of Physicians (ACP) has issued comprehensive guidelines for treating low back pain, recommending that clinicians avoid routine imaging and diagnostic tests. The ACP also found that the newer drug telbivudine is more effective than adefovir in suppressing hepatitis B virus levels.
A new biosensor can detect avian influenza virus in just minutes, improving quick identification and controlling outbreaks. The sensor is economical, field-deployable, sensitive to different strains and requires no labels or reagents.
A new study found that irregular Pap smears and false negative tests were not the primary reasons for cervical cancer development. Instead, socio-economic disparities in screening access may be a major obstacle to eradicating the disease.
Researchers developed a new blood test to detect liver cancer in an early stage, improving detection accuracy by 70%. The test uses the ratio of two sugar groups on blood proteins to identify liver cancer in patients with cirrhosis.
Early HIV testing for exposed infants can prevent infection before AIDS or death, allowing for prophylaxis or treatment implementation. Universal availability of prophylaxis or treatment is crucial, but poses challenges such as long-term toxic effects of anti-retroviral treatment.
A new study by Professor David Holtgrave in PLOS Medicine suggests that targeting HIV counseling and testing towards high-risk individuals is more effective than offering opt-out testing to everyone. The study found that this approach could prevent up to 36% of new HIV infections, while also improving diabetes care for ethnic minorities.
A targeted approach to HIV testing and counseling is more effective in identifying people with HIV and preventing new infections. The study estimates that for the same cost, a targeted program could diagnose over three times as many people with HIV and prevent four times as many new infections compared to the CDC's mass testing plan.
Researchers found that rapid syphilis screening during pregnancy can prevent congenital syphilis cases and improve child survival. Lithium also showed promising results in a mouse model of spinocerebellar ataxia, a devastating neurodegenerative disorder with no existing treatments.
A university-based ED implemented opt-out HIV screening, with 60% of patients agreeing to testing. The study resulted in a low cost per preliminary positive ($1,700) and confirmed cases of HIV infection ($4,900).
A recent study by researchers at the University of New South Wales and Sydney Children's Hospital found that a third of children with a predicted peanut allergy were not allergic when challenged with peanuts. This suggests that diagnostic tests for peanut allergy may have poor sensitivity and specificity.
A new MUHC-led study reveals the oral fluid-based OraQuick HIV1/2 test to be 100% accurate and a patient-preferred choice for HIV testing in rural India. The test demonstrated higher accuracy than traditional blood tests, with minimal discomfort during sample collection.
A new medical device developed by University of Cincinnati researchers could identify olfactory disorders that may be an early warning sign for Alzheimer’s disease, Parkinson’s disease, and other conditions. The Sniff Magnitude Test uses a simple observation to measure sniff size when detecting odors.
A Cornell researcher is working on a quick and affordable immune system test for people in the developing world. The test aims to help HIV/AIDS sufferers get proper treatment, potentially extending their lives by 10-15 years.
A study by UCLA researchers found that only 41% of primary care providers offered advice on sexually transmitted infections or safe sex, while 36% had offered more than 20 HIV tests. The study suggests that providers are testing patients who present with symptoms rather than proactively offering early detection.
A study found that rapid influenza testing led to decreased antibiotic use among hospitalized adults, with a 14% reduction in antibiotic discontinuation compared to those without positive test results. The findings suggest that prompt diagnosis and targeted therapy can help minimize unnecessary antibiotic use.
Researchers found a blood test ratio to be an effective alternative to the expensive mononucleosis spot test. The lymphocyte-white blood cell count ratio can correctly diagnose mononucleosis with high sensitivity and specificity, differentiating it from tonsillitis.
Researchers developed a sensitive test for identifying drug-resistant strains of HIV in patients' bloodstreams. The test detects genetic changes that predict potential drug resistance, enabling personalized treatment guidance.
Researchers have created a diagnostic test that can detect viruses like influenza, HIV, and RSV in under 60 seconds using surface-enhanced Raman spectroscopy (SERS). The technique works by measuring the change in frequency of a near-infrared laser as it scatters off viral DNA or RNA.
Scientists have developed an inexpensive gene chip test that can detect H5N1 infections with high accuracy, providing a significant advantage over existing tests. The MChip has the potential to revolutionize laboratory testing for influenza, enabling rapid and accurate identification of flu viruses, including avian influenza H5N1.
A recent study by the American Association for Cancer Research found that HPV tests are a better predictor of cervical cell abnormalities than Pap smears, particularly in older women. The researchers discovered that HPV-positive women aged 40 and above had a significantly higher risk of developing cervical cancer within 10 years.
Scientists reanalyzed 151 New York State samples using MassTag PCR, identifying nine previously undiagnosed pathogens, including six viruses and three bacteria. The analysis found that rhinoviruses were a major cause of influenza-like illness in the state during 2004.
A new microchip-based test called FluChip can distinguish among 72 influenza strains in under 12 hours, enhancing global flu surveillance efforts. This technology has the potential to increase laboratory diagnostic capacity and provide critical information on the geographic origin of emerging viruses.
Northwestern University has received a four-year, $4.9 million grant from the Bill & Melinda Gates Foundation to develop and produce affordable diagnostic devices for infectious diseases. The team will focus on two targeted products and work with commercial collaborators Abbott and Inverness Medical Innovations to improve test systems.
A new strategy detects high-grade precancerous lesions more effectively than traditional smear tests, while minimizing incorrect diagnoses. This approach enables early treatment and improves cure rates for young women aged 25-34 years.
A randomized controlled trial found that HPV testing combined with liquid-based cytology increased sensitivity by 47% compared to conventional pap smears, but also led to a 60% increase in false positives. HPV testing alone showed a 40% increase in sensitivity and a smaller decrease in specificity.
Researchers found that FDG PET scans can accurately diagnose fevers of unknown origin in half of cases, eliminating the need for further tests. The study suggests that FDG PET offers an effective tool for early diagnosis, risk stratification, and treatment, reducing hospital stays.
The Infectious Diseases Society of America calls for routine HIV testing to identify those who need treatment. Early testing and connection with care can save millions more lives beyond the three million already saved through antiretroviral therapy.
Recently reported cases of rodent virus transmission through organ donation highlight the need for a tracking system. Physicians should be vigilant in identifying clusters of symptoms following transplantation, as early detection can prevent further transmissions.
Researchers propose criteria for standardizing newborn hearing screening, including molecular genetic testing to identify common causes of birth-Expressed deafness. Prompt confirmation of abnormal results can dramatically improve educational outcomes for deaf infants.
A recent study highlights the importance of HIV testing for pregnant women, as even with treatment, an infected mother still poses a 25% risk of infecting her child. The use of rapid testing can significantly reduce this risk, but many women lack access to these tests due to lack of proof or electronic medical records issues.
A study analyzing patient data from over 60,000 women across six countries reveals HPV testing is highly sensitive and reproducible, with a sensitivity rate of 96% overall. Cytology was less effective but more specific in older women.
A Duke University Medical Center study found that free HIV tests are more cost-effective in preventing infections, drawing in three times as many people for testing. The research showed that the cost of prevention dropped from $170 to $92 per person when testing rates increased.
Researchers have developed hybrid antibodies from chimpanzees and humans that effectively inhibited the spread of vaccinia and variola viruses in test tube experiments. In mice infected with vaccinia virus, the hybrid antibodies proved more effective than anti-vaccinia immune globulin when given two days after virus exposure.
Researchers found HPV DNA testing to be a cost-effective strategy for women with ASCUS, detecting more precancer cases than immediate colposcopy. The approach was also less costly, making it economically viable.
A review of 56 studies found that liquid-based cytology did not detect more high-grade lesions and had equivalent performance to conventional Pap smear. However, the technique may have other advantages such as concurrent HPV DNA testing or reduced reading times.
The new blood safety test is capable of detecting major parasitic diseases, including malaria and fasciola, with instant results. Developed by the Montreal Neurological Institute (NRCP) at McGill University, the test has the potential to save countless lives by reducing the risk of parasite transmission through blood transfusions.
A new test developed by a McMaster virologist can identify infected individuals early in an outbreak, limiting the spread of virus in the community. The test will be available for evaluation by hospital-based laboratories and reference laboratories by early December.
A novel 'Flu Chip' developed at the University of Colorado at Boulder can determine the genetic make-up of influenza strains within 11 hours, significantly faster than current methods. The technology has shown over 90% accuracy in identifying flu subtypes and could aid global surveillance and vaccine development.
A new vaccine study is testing a targeted vaccine against the H5N1 strain of avian influenza, aiming to protect vulnerable populations. Participants will receive three doses of either the vaccine or placebo over six months, with blood samples collected to test for protection.
Researchers at Tulane University have received a multi-million dollar grant to develop diagnostic tests for hemorrhagic fevers, such as Lassa fever. The goal is to create tests that can be performed in biosafety level 1 labs, making them accessible in West Africa.
Scientists have found a biomarker, a protein called NF-H, that signals the presence of disease or injury in the blood and spinal fluid. The discovery could lead to a simple handheld device for diagnosing brain or spinal injuries with just a few drops of blood.
Research suggests that performing genotype resistance testing at the time of HIV diagnosis can guide treatment choices, increasing patient survival by over 14 months. The cost-effectiveness analysis indicates a cost of $23,900 per quality-adjusted life year gained, comparable to other HIV interventions.
The US Army's Gamma Phage Assay has been approved by the FDA for human use within the Laboratory Response Network (LRN), enabling early detection of anthrax bioterrorism threats. This test, developed with CDC support, is a classical bacteriological method that uses a virus to identify B. anthracis.
A Penn physician argues that explicit consent is not necessary for HIV testing in critically ill patients, as it can lead to earlier application of life-saving therapies and reduce costs. Alternative methods, such as surrogate consent or court-ordered testing, may be more effective but also pose challenges.
A new study at VGTI developed more accurate testing methods for monkeypox, which could be useful in a future outbreak. The researchers found that their test could detect the virus years after infection and even identify vaccinated individuals who were not showing symptoms.
A Dartmouth study found that traditional TB screening methods can miss active tuberculosis cases in HIV-positive individuals in developing countries. The study recommends using more sensitive and accurate TB culture tests, such as the one used in Tanzania.
A new method using quantum dots detects RSV in a matter of hours, reducing the need for lengthy tests. The system has potential benefits including increased proper use of antiviral medicines, reduced inappropriate antibiotic prescriptions, and improved patient separation.
Researchers at Johns Hopkins found that home test kits are highly effective in detecting Chlamydia and gonorrhea among young women. The study showed that 87% of participants used the internet to order the kit, and 95% of those who tested positive for Chlamydia sought treatment.
Researchers found that injecting a wart with a skin test antigen from mumps, Candida, or Trichophyton can clear the wart and other distant warts. Patients who responded to treatment were more likely to have an immune response to HPV, suggesting intralesional immunotherapy induces HPV-directed immunity.