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Caltech scientists control complex nucleation processes using DNA origami seeds

Researchers at Caltech have successfully created a system using DNA origami seeds that can direct the self-assembled growth of DNA tiles into precise forms. This breakthrough demonstrates unprecedented control over information-directed molecular self-assembly, paving the way for future applications in technology and materials science.

SourceCalifornia Institute of Technology·JournalProceedings of the National Academy of Sciences·DateApr 8, 2009

DNA constraints control structure of attached macromolecules

Researchers control RNA structure by attaching DNA strands, allowing precise folding and manipulation of RNAs. The technique also enables reversible or irreversible changes to molecular shapes, offering programmability and potential applications in biological and non-biological systems.

SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalJournal of the American Chemical Society·DateJun 28, 2005
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Nano-origami

Researchers at Scripps Research have created a single, clonable strand of DNA that folds into an octahedron with potential applications in biomedical science, electronics, and computing. The structure can be amplified and replicated using standard molecular biology tools.

SourceScripps Research Institute·JournalNature·DateFeb 11, 2004