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Glitch in protein synthesis could affect tumour growth

A glitch in protein synthesis, known as stop codon readthrough, may affect tumour growth and cancer cell proliferation. The study found that preventing this process can lead to increased degradation of target proteins and a delayed cell cycle, resulting in slower tumour growth.

Garmin GPSMAP 67i with inReach

Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.

An evolutionary roll of the dice explains why we're not perfect

A study found that in species with small populations, chance events take precedence over natural selection, allowing imperfections to creep in. The researchers analyzed the genetic instructions used by cells to make proteins and discovered that less efficient stop codons can increase in frequency due to chance events.

Rigol DP832 Triple-Output Bench Power Supply

Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

Can antibiotics cause autoimmunity?

Researchers discovered that antibiotics like gentamicin can cause abnormal proteins to be presented to the immune system, potentially triggering autoimmune disease. This approach, used to treat diseases in genes with truncated proteins, may come with a risk of initiating autoimmunity.

Study provides insight into cellular defenses against genetic mutation

A recent study has uncovered a natural quality control mechanism in cells that identifies and eliminates faulty messenger RNAs (mRNAs) containing premature stop codons, known as nonsense mutations. The mRNA-binding protein CBP80 plays a critical role in this process, allowing for the development of drug-based gene therapies to combat d...