Researchers found that small regions of the brain can momentarily 'flicker' awake while the rest of the brain remains asleep, and vice versa from wake to sleep. This challenges traditional understanding of sleep and wake patterns, which have been defined by slow, long-lasting waves.
Researchers discovered that propofol, a commonly used anesthesia drug, induces unconsciousness by causing the brain to become increasingly unstable. This instability leads to chaotic brain activity, resulting in loss of consciousness. The study's findings could help develop better tools for monitoring patients during general anesthesia.
A new model developed by Flatiron Institute researchers proposes that individual neurons exert more control over their surroundings, which could be replicated in artificial neural networks. This updated model treats neurons as tiny 'controllers' and may lead to better AI performance and efficiency.
A new tool, BioemuS, enables real-time emulation and hybridization of biological systems using biomimetic Spiking Neural Networks, addressing limitations of current pharmacological treatments. The system, developed through international collaboration, prioritizes cost efficiency and accessibility for closed-loop applications.
A new study on learning has provided insights into the balance between habitual and goal-directed behaviors, with implications for AI development. The research suggests that a balance between these two types of behavior is necessary for efficient and adaptable decision-making in AI systems.
A team of scientists has uncovered how our brains simulate possible future actions using stored memories. The prefrontal cortex and hippocampus work together to enable mental simulations, allowing us to make better decisions. This research provides foundational knowledge on brain circuits enabling decision-making.
Researchers at EPFL have developed a novel non-invasive technique to target deep brain regions involved in neurological disorders. By applying low-level electrical stimulation on the scalp, they can selectively stimulate key brain regions without invasive procedures.
Salk scientists develop new method to quantify synaptic features, revealing high precision of plasticity and up to 10 times more storage capacity. The technique uses information theory to analyze synapse pairs from a rat hippocampus, offering a scalable approach for studying brain function.
Neurons exhibit 'mixed selectivity,' integrating multiple inputs and computations, ensuring focused cognition. The brain employs mechanisms like oscillations and neuromodulators to recruit neurons and tune them to relevant information.
Researchers at Janelia Research Campus have released Kilosort4, an updated version of the popular spike-sorting software that requires less manual work and is more accurate. The new software improves processing and allows for easier use, making it indispensable for neuroscientists worldwide.
Researchers developed a new open-source system to interface with living neurons, offering enhanced control and precision in measuring neural processes. The system boasts over 500 electrodes, allowing for more data collection and customization, while being 10 times cheaper than commercial systems.
Researchers found large individual differences in roundworm neural activity despite conserved neural circuits. Computer simulations including noise accurately model whole-brain activity, shedding light on neuronal connectivity and essential role of noise in brain function.
A new neuroscientific paradigm, the synergistic model, allows better understanding of brain-body-environment interactions. This framework enables more accurate personalized diagnoses and treatments of brain diseases.
Researchers discovered how insects navigate using limited brain power by simplifying complex problems through their behavior, a strategy that can be applied to robots and computers. A model of insect neuronal activity showed the robot successfully navigated in various environments, leading to potential improvements in energy efficiency.
The Cognitive Neuroscience Society Conference in Toronto will explore the nature of thought and cognition. Registered press members will have access to scientific talks, posters, and receptions.
Researchers have designed a new, affordable system to study neural interactions and compute using living neurons. The open-source MiV system boasts over 500 electrodes, offering improved control and precision in measuring neural processes.
Researchers found that brain waves are slower in deep cortical layers and faster in superficial layers, with gamma waves dominating the topmost layers. These oscillations may play a fundamental role in brain function and contribute to disorders such as attention deficit hyperactivity disorder.
The European Commission has awarded €38 million to further develop EBRAINS, a digital ecosystem for neuroscientific research. The project aims to establish a new standard for brain atlases and push forward digital twin approaches.
A team of researchers led by Keith Hengen proposes a theory that explains both the meaning of sleep and the complexity of the brain. By tracking brain activity in sleeping rats, they found that sleep restores criticality, a state that maximizes thinking and processing.
A new study finds that complex and unfamiliar sentences generate stronger responses in the brain's language processing centers. Sentences with higher surprisal and linguistic complexity evoke more activation, while extremely simple or nonsensical sequences elicit little response.
A new tool called Facemap uses deep neural networks to relate mouse facial movements to neural activity in the brain. This allows researchers to track and quantify movements and correlate them with brain activity, bringing them one step closer to understanding how the brain uses persistent, widespread signals.
Research suggests that consciousness requires synchronized communication across cortical regions; propofol general anesthesia cancels sensory processing by cutting it off. Neural activity in higher-level processing and cognitive regions fails to propagate during anesthesia.
Researchers are combining biology, physics, computer science, and engineering to design electric circuits that mimic the brain's adaptive behavior. The goal is to create a more efficient AI application that can learn from history and adapt without significant energy consumption.
Researchers at King's College London are studying the effects of maternal prenatal exposure to COVID-19 infection on children's brain development. The six-year study will explore how the maternal immune system affects fetal brain development and identify potential impacts on childhood outcomes.
Researchers found that deep neural networks often respond the same way to images with no resemblance to the target, generating unnatural signals. The models develop unique invariances that are different from human perceptual systems, causing them to perceive pairs of stimuli as similar despite their differences.
Fruit flies use a unique toggle-switch in their brains to switch between solo and mating songs, exchanging information through dialogue. Researchers decoded the tiny brains' behavior using neural imaging and AI, providing insights into complex brain decision-making.
Researchers have found that neural activity in the brain changes between sensing a stimulus and taking action, regardless of the context. This discovery has implications for understanding executive functions and potentially aiding in the development of autonomous vehicle systems.
Researchers have created the first-ever map of a single animal's early visual system, reconstructing it from the eyes to neurons in a tiny parasitic wasp. The study reveals complex behaviors such as flight in an insect with just 8,600 cells compared to the human brain's 171 billion.
In a new study, researchers deciphered mice's behavior during reward-based learning tasks, finding they persistently blend multiple strategies. The findings suggest mice do not fully adopt optimal approaches, and their ability to shift between strategies is crucial for understanding their decision-making process.
The Fralin Biomedical Research Institute at VTC will accelerate health sciences research with a focus on cancer and brain disorders. The institute will recruit 14 researchers and support six major projects.
A team of scientists has developed a rigorous accounting of the neurons in the tiny brain of a humble C. elegans worm, mapping out how its brain cells encode essential behaviors such as movement and feeding. The atlas reveals the underlying logic of how the worm's brain produces a sophisticated repertoire of behaviors, even as environm...
Researchers propose a hypothesis that astrocytes, non-neuronal cells in the brain, can perform core computation as transformers, providing insights into human brain function and machine learning success. This discovery could spark future neuroscience research and help explain transformer performance across complex tasks.
A study published in Neuron found that a structure in rat brains called the periaqueductal gray is essential for play and laughter. The researchers used tickling to simulate playful environments and measured brain activity, finding strong neural responses to both tickling and playing.
Researchers found that nearly all Purkinje cells in the human cerebellum have multiple primary dendrites, which contradicts the traditional understanding of a one-to-one relationship between climbing fibers and Purkinje cells. This discovery was made possible by analyzing thousands of cells from both human and mouse tissue using immuno...
Researchers created a simplified mathematical analysis to visualize neuron activities in daily experiences, employing state-space analysis. This technique allows for visualization of neuronal activity using general statistical software, revealing changes in brain activity over short time periods.
Human metacognitive behavior is distinct from AI's reward-punishment system, with humans adjusting memory retention in response to gain and learning speed in response to loss. This asymmetric property may provide insights into the neural mechanisms underlying human metacognition.
A recent study published in Nature Neuroscience clarifies the connection between autism and the microbiome, identifying autism-specific metabolic pathways associated with particular human gut microbes. The analysis, which harmonized dozens of previously published datasets, reveals a common microbial signature distinguishing autistic fr...
Researchers mapped receptor densities across the cortex, identifying two main arrangements that align with functional systems. The findings provide insights into how the brain adapts to a changing world, with potential applications for computational models and neuroscientific research.
Researchers at MIT have designed a computational model that can predict other people's emotions, including joy, gratitude, and regret. The model uses insights into human intuition, incorporating factors such as desires, expectations, and observation of actions to make predictions.
Researchers at the University of Rochester Medical Center found that predicting movement is crucial for eye-and-hand coordination. The study used high-speed cameras and AI methods to analyze primate behavior and developed a detailed model of vision-guided reaching behavior.
Researchers at Sainsbury Wellcome Centre found that instinctual exploratory runs enable mice to learn a map of the world efficiently. The study demonstrates how biological brains can learn faster and more efficiently than AI agents by focusing on salient objects.
A groundbreaking study published in Nature Neuroscience shows that monkeys can think deeply about problems, consider multiple factors, and find optimal outcomes. This discovery challenges traditional views on animal intelligence and highlights the complexity of monkey cognition.
The Human Brain Project has achieved significant scientific breakthroughs, including world-leading 3D brain atlases and personalized medicine based on computational modeling. The project's legacy will leave a lasting impact on the research community.
Researchers have developed a multidisciplinary approach using a new microscope, artificial intelligence algorithm, and voltage indicators to better measure brain activity. The technique enables the imaging of up to 100 neurons at a time, far surpassing previous limits.
Dr. Nico Spiller to develop new analysis methods using machine learning to analyze complex brain data related to memory, decision making, and movement. The fellowship aims to provide insights into neurodegenerative diseases such as Alzheimer's and Parkinson's disease.
Neuroscientists have uncovered a brain circuit that enables mice to rapidly escape to shelter when faced with a threat. The retrosplenial cortex and superior colliculus form a circuit that encodes the direction to a shelter, allowing mice to accurately orient and escape.
Researchers propose that delayed recoveries in COVID-19 patients may be due to a protective response from their brains, similar to those seen in animals exposed to extreme conditions. This theory could lead to new approaches for ICU sedation and recovery from disorders of consciousness.
The Keck School of Medicine's Stevens INI has received a nearly $2 million grant to upgrade its storage system, increasing its capacity to handle vast amounts of brain imaging data. This will enable the lab to maximize scientific productivity and fulfill its promise to collaborate with researchers globally.
Researchers from Xi'an Jiaotong-Liverpool University found that brain stimulation combined with a nose spray containing nanoparticles can improve recovery after ischemic stroke. The treatment increased cognitive and motor functions, and weighed more quickly than those treated with TMS alone.
A new theory developed by a collaboration between a former cosmologist and a computational neuroscientist has identified essential connections between brain cells. The theory, published in Physical Review Research, uses geometric framework to predict structure from function in neural networks.
Researchers found that two types of computer models, deep neural networks and the Basel Face Model, are surprisingly accurate at replicating human facial similarity judgments. These models were tested on a dataset of realistic computer-generated faces and ranked by students in terms of similarity.
A new GPU-based machine learning algorithm, ReAL-LiFE, can rapidly analyze large amounts of data from diffusion Magnetic Resonance Imaging (dMRI) scans of the human brain. This allows for faster analysis and prediction of brain connectivity, enabling better understanding of brain-behaviour relationships at scale.
Researchers from the University of Tsukuba develop a model that combines multiple theories to simulate motor learning in humans. The study found that larger amounts of motor exploration aid in learning sensitivity derivatives and transforming errors into motor corrections.
A new AI system uses artificial neural networks to recognize objects more accurately and stably, despite changing visual inputs. The system mimics human eye movements to improve machine vision capabilities, reducing errors in self-driving cars and other applications.
Researchers found that walking enhances performance on cognitive tasks in 14 participants by increasing frontal brain function, while 12 others showed no improvement. This discovery highlights the flexibility of a healthy brain and has implications for understanding aging and neurological disorders.
Researchers at the Sainsbury Wellcome Centre discovered that brain area communication is dynamic and changes over rapid timespans, with influences varying on a fast timescale. This finding suggests that cortical areas may control different aspects of processing in downstream regions over very short time spans.
A new circuit model provides an explanation for how deep brain stimulation (DBS) relieves Parkinson's disease motor symptoms by interrupting a vicious cycle between the subthalamic nucleus and the striatum. The model suggests that DBS restores a balance with other rhythm frequencies, enabling better movement control.
A new study by MIT scientists reveals that propofol anesthesia significantly alters the state of brain waves, with lower frequency delta waves dominating. Higher frequency beta waves decrease in structure and power, with their traveling nature disrupted by the surging delta waves. The findings suggest a profound impact on consciousness.
A study by Tokyo University of Science researchers has demonstrated that a computationally-light model can simulate complex brain cell responses, including periodic and quasi-periodic responses. The Izhikevich neuron model was found to be capable of reproducing both types of responses at lower computational cost.
Scientists at Johannes Gutenberg University discovered that fruit fly eyes can distinguish six types of global motion patterns generated by self-motion. The T4/T5 cell subtypes directly represent complex motion cues rather than uniform directions, matching the fly's actual behavior closely.