Articles tagged with Neuroimaging
Researchers at Brown University have developed a new imaging technique to track changes in blood vessels in the brains of mice, which could lead to early detection of neurodegenerative diseases. The method uses advanced imaging techniques and AI algorithms to identify biomarkers that may predict disease onset.
A 13-year study led by UTEP professor Arshad M. Khan mapped specific cell populations in the brain responsive to rapid changes in blood sugar. The discovery could lead to more targeted therapies for individuals with Type I and Type II diabetes.
Researchers have identified a brain marker that may indicate future suicide risk, suggesting potential new treatments and prevention strategies. The study found differences in brain connections among veterans with a history of suicide attempts compared to those without, which could help identify individuals at risk.
The development of SimulScan technology will help clinicians diagnose disordered swallowing more accurately. The researchers aim to investigate how swallowing behaviors change across the lifespan to create personalized treatments for patients with dysphagia.
Researchers discovered a new genetic variant in the Reelin gene that provides protection from Alzheimer's disease. The variant was identified through clinical assessments, genetic and molecular studies, and neuropathological analysis of two patients with a similar genetic predisposition to developing early-onset Alzheimer's disease.
Researchers develop innovative data compression scheme to facilitate multispeckle diffuse correlation spectroscopy with high pixel resolutions, enabling non-invasive measurement of brain blood flow. The scheme uses field-programmable gate array compression to alleviate computational burdens and expand the use of SPAD cameras in biomedi...
A new high-speed two-photon microscope was developed with an unprecedented line scanning frequency of 400 kHz, achieving up to 10,000 frames per second. This allowed for precise observations of complex biological processes in living tissues, including calcium signal propagation and blood flow measurements.
A new MRI approach uses harmless glucose solution to map brain glucose metabolism, generating reliable results and potentially improving diagnosis of conditions like Alzheimer's and cancer. Further studies are needed to confirm the findings and deploy this less-invasive method for patients.
A new study published in JAMA Network Open found that intensive blood pressure treatment significantly reduces the risk of adverse cerebrovascular events such as stroke. Participants with hypertension who received intensive treatment showed reduced white matter lesions and improved blood flow, indicating better overall brain health.
Researchers at Gladstone Institutes have made a groundbreaking discovery about how neurons consume and metabolize glucose, a process crucial for maintaining normal energy levels. The study found that neurons rely on glycolysis to break down glucose, and its disruption can lead to severe learning and memory problems in mice.
A recent study published in NeuroImage found that older adults with improved cognitive performance during dual-task walking had flexible neural resource allocation. This discovery suggests a potential method for tracking brain health and identifying individuals at risk of aging-related cognitive decline.
Researchers at Duke University have successfully improved the resolution of Magnetic Resonance Imaging (MRI), capturing images of a mouse brain with unprecedented sharpness. The breakthrough allows for the visualization of microscopic details within the brain, enabling new insights into neurodegenerative diseases such as Alzheimer's an...
Researchers developed a new imaging technique that visualizes the interaction between reactive astrocytes and neurons in the brain, revealing a potential breakthrough in Alzheimer's disease diagnosis and treatment. The study found that acetate promotes reactive astrogliosis, leading to dementia, and offers a new target for AD treatment.
A novel technique of three-dimensional (3D) slice-to-volume (SVR) MRI allows for precise delineation and measurement of the fetal optic pathway (FOP). The study found that FOP was visualized in 9 cases in unprocessed fetal MRIs, compared to 55 cases in 3D SVR images.
Researchers found that players' brains respond differently to human and machine opponents, with desynchronization indicating active calculations. The study suggests that training with machines may not replicate the experience of playing against humans.
Research suggests that lonely people process information in unique ways, differing from their peers, even with large social networks. This difference may lead to a reduced sense of understanding and further challenges in achieving social connection.
Researchers at Janelia have developed the fastest calcium indicators yet, allowing them to tease out individual neuronal signals with unprecedented speed and sensitivity. The new jGCaMP8 sensors can detect calcium ions nearly as fast as they are released from neurons, enabling scientists to study neural computations at the molecular le...
A new study published in Neurology shows that younger brain age is associated with superior post-stroke outcomes, suggesting a potential biomarker for stroke rehabilitation. The research team used multi-site data sets and 3D brain structural MRIs to analyze the relationship between brain age and stroke recovery.
Researchers analyzed 557 subjects to link genetic variations, brain structure, and behavior to intelligence test performance. They found specific brain areas where gene variations influence brain characteristics, which in turn affect intelligence.
The Peking University team has developed a miniature three-photon microscope that successfully captured deep-brain images of freely moving mice. The new device features an innovative optical configuration, maximizing the collection efficiency of scattered fluorescence and achieving low phototoxicity.
A new study from Mass General Brigham researchers found that early menopause may be a risk factor for Alzheimer's disease dementia. However, women who received hormone therapy around the time of menopause onset did not experience an increased risk of dementia. The study suggests that timing is crucial when it comes to hormone therapy, ...
Biyu J. He's groundbreaking research on perceptual cognition and subjective experience has challenged traditional views of consciousness. Her work explores how past experiences shape individual perception and understanding, using innovative techniques like fMRI and EEG.
A large-scale study found that diagnostic errors in neuroradiology were associated with longer interpretation times and higher shift volumes. The study also revealed a significant increase in diagnostic errors during weekend work, highlighting the need for targeted quality improvement interventions.
A literature review published by the Society of Nuclear Medicine and Molecular Imaging reveals how nuclear medicine brain imaging can help evaluate biological changes causing chemotherapy-related cognitive impairment. The findings confirmed the impact of chemotherapy drugs on cognitive function and highlighted the utility of various SP...
Researchers have developed a multidisciplinary approach using a new microscope, artificial intelligence algorithm, and voltage indicators to better measure brain activity. The technique enables the imaging of up to 100 neurons at a time, far surpassing previous limits.
High blood pressure damages specific brain regions, including the putamen and white matter areas, leading to cognitive decline and increased risk of dementia. The study uses a combination of MRI, genetic analyses, and observational data to identify these affected regions.
A new study links shorter telomeres to multiple changes in the brain associated with dementia, including reduced grey matter volume and a thicker cerebral cortex. Longer telomeres were found to be protective, reducing the risk of dementia but not stroke or Parkinson's disease.
A new study has uncovered the brain's internal compass, which helps it navigate changing environments. The research found that the brain uses a mechanism called 'network gain' to reorient itself after being disoriented, allowing for rapid recovery of its sense of direction.
Researchers have created wearable microscopes to produce high-definition, real-time images of mouse spinal cord activity across previously inaccessible regions. This technology enables unprecedented insight into the neural basis of sensations and movement in healthy and disease contexts.
A new Boston University study suggests that repetitive blows to the head in tackle football may lead to less white matter in the brain, potentially causing impulsive behavior and other cognitive issues. Researchers found players who start playing at a young age or play for over 11 years are at greater risk.
A Rutgers study found that criteria used to diagnose multiple sclerosis in adults may not be sufficient for pediatric patients, who often go undetected in early stages. The study suggests that diagnostic tools used for adults may need to be re-evaluated for children with abnormal MRI findings.
Researchers from Dartmouth and University Medicine Essen found that strong links between brain measures and traits can be obtained when machine learning algorithms are utilized. This approach allows for high-powered results from moderate sample sizes, opening up studies of many traits and clinical conditions previously inaccessible.
Researchers developed temporal compressive super-resolution microscopy (TCSRM) to overcome optical diffraction's spatial resolution restriction. TCSRM achieves high-speed imaging at 1200 frames per second with a spatial resolution of 100 nanometers, enabling observation of fast dynamics in fine structures.
A meta-analysis of 34 studies found a significant association between autism spectrum disorder (ASD) and increased risks of developing diabetes, dyslipidemia, and heart disease. Children with ASD were more likely to develop these metabolic complications, prompting clinicians to monitor them closely.
A new consensus statement calls for routine radiological screening of contact children in suspected child physical abuse cases to prevent further harm. Siblings are at risk of experiencing physical abuse, with a strong association between index and contact children.
A new screening tool developed by Cleveland Clinic researchers can effectively detect mild cognitive impairment, early Alzheimer's disease, and other related dementias in older adults. The tool has been shown to identify 90% of patients with mild cognitive impairment, offering a potential solution for early detection and prevention.
Scientists at Max-Planck-Gesellschaft created an interactive atlas of gene expression in the zebrafish brain, revealing hundreds of genes with single-cell resolution. The new map integrates seamlessly with existing data, providing new insights into neural structure and function.
The Vilcek Foundation will award three Vilcek Prizes for Creative Promise in Biomedical Science to rising immigrant scientists. The prizes recognize and celebrate their contributions to their field.
Researchers discovered a significant increase in serotonin transporter density in the midbrain of patients with PMDD during the periovulatory phase, which was associated with increased depressed mood. The study suggests that taking SSRIs at specific times during the menstrual cycle may help target these changes and alleviate symptoms.
Researchers discovered that neurons in the deepest part of the neocortex exhibit sensory responses and experience-dependent plasticity. The study found that these cells, known as L6b/surviving subplate neurons, play a role in the maturation of cortical functions.
A neuroimaging study of 8,900 children aged 9-11 reveals sex differences in brain connectivity and cognitive performance. The findings suggest that girls mature faster than boys, which may impact future development of brain developmental trajectory charts.
The ENIGMA Initiative aims to bridge knowledge gaps on brain aging factors in developing countries, particularly in India. The study will collect comprehensive data on risk and protective factors through clinical interviews, bloodwork, and brain MRI to identify universal and population-specific predictors of dementia.
Kyoto University researchers have created a map comparing circuit structure with neural activity in mammals, revealing a new mechanism behind visual cortex activities. This discovery sheds light on the hidden connections between neurons and could provide directions for constructing power-efficient deep neural networks.
Research found PIRI to be an independent predictor of infarct growth rate and 90-day outcomes in large-vessel occlusive stroke. The study suggests PIRI may help identify patients who could benefit from late-window endovascular thrombectomy.
Researchers developed a new imaging technique revealing abnormal circulation patterns of brain fluid in developing brains. Disruptions to cerebrospinal fluid flow may underlie cognitive deficits and developmental delays in conditions like hydrocephalus.
Researchers propose using brain scans to measure similarity in trademark cases, reducing inconsistencies and bias. This approach provides a reliable method for determining similarity without relying on subjective surveys or expert opinions.
A novel nuclear medicine imaging protocol, dual-phase amyloid PET, can assess both amyloid deposition and neurodegeneration with a single tracer injection, cutting costs and radiation exposure. The protocol was shown to be comparable in distinguishing patients with neurodegenerative diseases from controls.
A new study found that children with conduct disorder who experienced childhood maltreatment have more extensive brain structural changes compared to those without maltreatment. The study highlights the unique contribution of childhood maltreatment to these changes and provides neurobiological insights into the heterogeneity of CD.
A new American Heart Association scientific statement outlines ideal foundational requirements for stroke program development and growth. The guidelines aim to minimize inconsistencies and improve services provided by certified stroke centers across the U.S., emphasizing leadership, personnel resources, and quality improvement.
Researchers discovered that bone marrow transplants can halt the development and progression of brain blood vessel disease in adults with sickle cell disease. The study found that receiving stem cell transplants led to positive changes in blood vessels, reducing the risk of stroke among patients with the condition.
A 20-year study reveals that recent advances in surgical and clinical care have significantly reduced brain injuries in babies with congenital heart disease. Infants who received higher postoperative blood pressure had a 20% lower risk of brain injury compared to those in earlier stages.
The Chan Zuckerberg Initiative grant will support advanced imaging training for over 2,000 scientists through a combination of hands-on events and online resources. Array tomography, an imaging technique that offers higher resolution and detailed molecular labeling, will be a key focus of the project.
Researchers created monthly infant brain atlases to track normative trends in brain development. The atlases reveal changes in brain structure, cortical geometry, and tissue contrast, shedding light on conditions like ADHD and dyslexia. The study aims to facilitate discovery of new insights into child cognition and social behavior.
Researchers found that patients diagnosed with behavioral-variant frontotemporal dementia may have a cerebrospinal fluid leak, which can be treated. The study discovered CSF-venous fistulas in nine patients, who had their symptoms reversed after surgical closure.
The Cognitive Neuroscience Society Conference in San Francisco will explore the nature of thinking and memory. Highlights include presentations on aging, neurotechnology, and learning.
Researchers from the University of Queensland created a detailed outline of the cuttlefish brain structure and neuronal network, shedding light on their camouflage abilities. The study reveals that the cuttlefish's brain adaptations reflect their daily life requirements and ecology.
A new American Heart Association scientific statement emphasizes the importance of rapid evaluation for TIA, which can lead to full-blown stroke. The statement offers a standardized approach to evaluating people with suspected TIA, including guidance for hospitals in rural areas with limited resources.
A recent Yale-led study failed to replicate findings linking brain activity to post-traumatic stress disorder (PTSD) symptoms, highlighting the need for more research to develop reliable models. The study suggests that neuroimaging technology still has kinks to be ironed out before it can accurately diagnose psychiatric disorders.
A nationwide registry of AVM patients from 52 hospitals in mainland China investigated the efficacy of different treatments on patient groups. The study found that categorizing treatment strategies based on disease severity is an ideal approach, and a multidisciplinary comprehensive assessment promotes individualized treatment protocols.
A new longitudinal study examines neural-based correlates and risk factors for nonsuicidal self-injury (NSSI) among adolescents. The study found that greater amygdala reactivity during anticipation of social punishment predicted NSSI engagement one year later, particularly in those with lower peer-nominated social preference.