Articles tagged with Neuromodulation
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
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Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
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Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers observed that chandelier cells, which regulate cortical circuit activity, communicate with other neurons shortly after birth, influencing brain development. This interaction is crucial for normal brain function and may be disrupted in neurological disorders.
The International Neuromodulation Society 15th World Congress will feature over 470 abstracts and plenary lectures on neuromodulation therapy. Researchers from around the world will gather in Barcelona to discuss scientific theory and clinical applications of neuromodulation therapies.
A new study published in Science Advances has shown that transcranial ultrasound (TUS) can disrupt the brain's credit assignment processes, leading to more exploratory decisions. The study also found that TUS selectively alters behavior without affecting other brain regions.
A new review study explores the potential of neuromodulation therapies, including rTMS and ECT, in treating depression. The study suggests that these treatments offer promise and can be used in combination with other modalities to improve efficacy.
A pilot study examines graph-theoretical properties of brain networks in traumatic brain injury and controls, showing association with balance impairment and structural damage. The study uses EEG-based functional connectivity measures during a balance perturbation task to explore underlying neural mechanisms.
Research in mice reveals that coordinated clock-gene and neuronal activity rhythms are necessary for daily hormone release, with the suprachiasmatic nucleus (SCN) and paraventricular nucleus (PVN) working together to generate circadian rhythms. Disruption of these clocks can lead to various pathologies.
A team of researchers at the Marine Biological Laboratory has developed a system called HySyn, which uses neuropeptides from Hydra to synthetically reconnect neural circuits in the C. elegans brain. This allows for the creation of an artificial synapse that rewires a behavioral circuit, enabling the worm to communicate more effectively.
Researchers use X-rays to activate opsins in neurons, allowing for remote control of neural function and behavior. Scintillators emit visible light in response to X-ray irradiation, enabling the technique without tissue damage.
Researchers summarize the mechanism of ultrasound neuromodulation, which uses focused ultrasound to regulate neural circuits. The treatment shows promise for treating various neurological disorders, including epilepsy and depression, with potential for future developments in genetic engineering or nanotechnology.
Researchers at Carnegie Mellon University have developed a new noninvasive therapy using low-intensity focused ultrasound that can target specific cell types in the brain. The technology has shown promise in treating conditions such as Parkinson's Disease, epilepsy and insomnia.
Scientists at UCSF have developed a personalized neuromodulation approach that targets individual patients' distinctive symptoms, providing relief from severe depression within minutes. The approach uses stereo-EEG to map brain regions and identify optimal stimulation sites.
Researchers developed a noninvasive ultrasound neuromodulation technique that inhibits epileptiform activities with an efficiency exceeding 65% in biopsy specimens from epileptic patients. The study demonstrates the potential clinical use of low-intensity pulsed ultrasound stimulation for epilepsy treatment.
A new clinical trial tests a cell-phone-sized device that stimulates the vagus nerve to prevent and treat migraine attacks. The device has shown promise in preventing and combating migraine attacks through its proprietary stimulation method, offering a non-invasive treatment option with minimal side effects.
Researchers have developed an injectable, flexible electrode that can reduce the cost of neuromodulation therapy, increase its reliability and make it less invasive. The 'injectrode' uses a liquid that cures in the body to create a wired contact, allowing for more elasticity and flexibility compared to traditional rigid implants.
A clinical trial published in Appetite found that transcranial direct current stimulation (tDCS) can reduce or increase appetite depending on a patient's genetic profile. The study used a current of 2 milliamperes and 17 thirty-minute sessions over a month, with participants monitored for six months.
The UAB clinic has achieved rapid accessibility and improved seizure control for patients with drug-resistant epilepsy. Vagal nerve stimulation (VNS) and responsive neurostimulation (RNS) therapies have shown promise, with 12-11 out of 27-16 patients experiencing a 60% reduction in seizures.
The 2019 International Brain Stimulation Award recognizes Mark Hallett's pioneering work in developing transcranial magnetic stimulation (TMS) and advancing the field of neuromodulation. His research has led to new treatments for neurological and psychiatric conditions, including depression and OCD.
Researchers at UT Southwestern Medical Center have made a breakthrough in treating autistic children with neuromodulation, which restored social impairments. The study found that stimulating a specific part of the cerebellum improved social behaviors in both mice and humans, offering new hope for autism treatment.
A multi-disciplinary team of researchers has received a $9 million grant to develop enhanced infrared light technology for treating diseases such as cardiac arrhythmias, high blood pressure, asthma, and diarrhea. The technology aims to stimulate or inhibit electrical signals in the nervous system with laser precision.
Dr. Michael Stanton-Hicks is a pioneer in the management of complex regional pain syndrome (CRPS), with extensive contributions to neurostimulation and chronic pain research. He has bridged advances in neurostimulation, taxonomizing CRPS, and improved patient care through his work at the Cleveland Clinic.
Six abstracts selected for their innovative therapy approaches and basic research providing knowledge to improve treatment or clarify mode of action. These include a new functional treatment for chronic low back pain and stimulation effects on postural instability in Parkinson's disease.
Several emerging companies are developing innovative neuromodulation therapies to alleviate conditions such as autism spectrum disorder, spinal cord injury, and persistent pain. BioInduction Ltd.'s Picostim and BlueWind Medical's RENOVA iStim aim to provide targeted stimulation for various clinical indications.
A new study compares Botox to sacral neuromodulation as treatments for urge incontinence, finding that Botox provides more daily relief but may be associated with more adverse events. The study analyzed data from 381 women and found a significant reduction in symptoms with botulinum toxin.
Dr. Barker's groundbreaking research on transcranial magnetic stimulation (TMS) has revolutionized the field of neuroscience, enabling precise and pain-free brain stimulation. His invention has opened up new avenues for understanding brain function and treating neurological and psychiatric conditions.
Yevgenia Kozorovitskiy, a Northwestern University neurobiologist, has been awarded a $750,000 Beckman Young Investigator grant to discover how chemical neuromodulatory systems work together to support complex behaviors. The award supports her research on using optical microscopy techniques and classical neuroscience technologies.
Researchers at Berkeley Lab found that proper copper levels modulate spontaneous neural activity in developing circuits, which is critical for brain health and development. The study highlights the importance of managing copper levels to prevent misregulation of signaling in cell-to-cell communications.
A new robot technology called RP-7 enables remote presence in programming brain and spine stimulators, allowing non-expert nurses to be guided by specialists. The study found no significant difference in accuracy or clinical outcomes between remote-presence and conventional programming.
A new study published in Archives of General Psychiatry found that deep brain stimulation is a safe and effective intervention for treatment-resistant depression in patients with unipolar and bipolar disorders. After four weeks of single-blind stimulation, 58% of patients achieved remission and showed significant improvement in function.
Researchers have produced a comprehensive guide for using low-intensity, pulsed ultrasound to non-invasively stimulate brain circuits. The approach holds promise for treating life-threatening epileptic seizures and has been shown to be effective in animal studies.
Researchers found that subliminal words can produce a priming effect, where subjects respond faster on tasks related to either the visual or auditory word. TMS applied to specific brain areas disrupted this priming effect, demonstrating top-down processing of subliminal information.
A new neurostimulation system uses continuous electric field adjustments to provide real-time, dynamic paresthesia steering for improved pain relief. This innovative technology enables up to 71 combinations of stimulation settings, leading to enhanced therapeutic possibilities.