Articles tagged with Neuromodulation
A research team has won the NIH's Neuromod Prize for their innovative approach to spinal stimulation, which uses autonomic neuromodulation to regulate nervous system activity. The breakthrough could lead to improved autonomy and daily functioning for people with spinal cord injuries.
A novel network analysis technology can pinpoint seizure originating brain regions and predict a patient's seizure outcome before surgery, using only 10 minutes of resting state recordings.
A new study suggests that supplementing a diet with Ascidiacea, also known as sea squirts, reverses some main signs of aging in animal models. The researchers found that plasmalogens, vital to body processes, decrease with age and contribute to neurodegenerative diseases like Alzheimer's and Parkinson's.
A new study published in Bioelectronic Medicine found that high-frequency spinal cord stimulation (HF-SCS) was more effective at improving perceived pain reduction than low-frequency SCS (LF-SCS). HF-SCS also showed less subsequent use of opioids to mitigate pain.
Dystonia is characterized by involuntary movements and postures, limiting daily activities. A new study maps specific brain networks for treatment success in patients with cervical and generalized dystonia. The findings reveal distinct stimulation sites depending on the type of dystonia, offering a more targeted approach to improving t...
A new wireless implant has the potential to treat neuropathic pain resistant to medical therapy, offering a minimally invasive alternative to surgery. The device uses bioelectronic therapy to stimulate peripheral nerves from within blood vessels, providing precise placement and predictable outcomes.
Researchers at Boston University have developed optoacoustic neurostimulation with single neuron and subcellular level precision. Optoacoustic neuromodulation may offer advantages over ultrasonic neuromodulation, including higher spatial temporal resolution.
Researchers observed that chandelier cells, which regulate cortical circuit activity, communicate with other neurons shortly after birth, influencing brain development. This interaction is crucial for normal brain function and may be disrupted in neurological disorders.
The International Neuromodulation Society 15th World Congress will feature over 470 abstracts and plenary lectures on neuromodulation therapy. Researchers from around the world will gather in Barcelona to discuss scientific theory and clinical applications of neuromodulation therapies.
A new study published in Science Advances has shown that transcranial ultrasound (TUS) can disrupt the brain's credit assignment processes, leading to more exploratory decisions. The study also found that TUS selectively alters behavior without affecting other brain regions.
A new review study explores the potential of neuromodulation therapies, including rTMS and ECT, in treating depression. The study suggests that these treatments offer promise and can be used in combination with other modalities to improve efficacy.
A pilot study examines graph-theoretical properties of brain networks in traumatic brain injury and controls, showing association with balance impairment and structural damage. The study uses EEG-based functional connectivity measures during a balance perturbation task to explore underlying neural mechanisms.
Research in mice reveals that coordinated clock-gene and neuronal activity rhythms are necessary for daily hormone release, with the suprachiasmatic nucleus (SCN) and paraventricular nucleus (PVN) working together to generate circadian rhythms. Disruption of these clocks can lead to various pathologies.
A team of researchers at the Marine Biological Laboratory has developed a system called HySyn, which uses neuropeptides from Hydra to synthetically reconnect neural circuits in the C. elegans brain. This allows for the creation of an artificial synapse that rewires a behavioral circuit, enabling the worm to communicate more effectively.
Researchers use X-rays to activate opsins in neurons, allowing for remote control of neural function and behavior. Scintillators emit visible light in response to X-ray irradiation, enabling the technique without tissue damage.
Researchers summarize the mechanism of ultrasound neuromodulation, which uses focused ultrasound to regulate neural circuits. The treatment shows promise for treating various neurological disorders, including epilepsy and depression, with potential for future developments in genetic engineering or nanotechnology.
Researchers at Carnegie Mellon University have developed a new noninvasive therapy using low-intensity focused ultrasound that can target specific cell types in the brain. The technology has shown promise in treating conditions such as Parkinson's Disease, epilepsy and insomnia.
Scientists at UCSF have developed a personalized neuromodulation approach that targets individual patients' distinctive symptoms, providing relief from severe depression within minutes. The approach uses stereo-EEG to map brain regions and identify optimal stimulation sites.
Researchers developed a noninvasive ultrasound neuromodulation technique that inhibits epileptiform activities with an efficiency exceeding 65% in biopsy specimens from epileptic patients. The study demonstrates the potential clinical use of low-intensity pulsed ultrasound stimulation for epilepsy treatment.
A new clinical trial tests a cell-phone-sized device that stimulates the vagus nerve to prevent and treat migraine attacks. The device has shown promise in preventing and combating migraine attacks through its proprietary stimulation method, offering a non-invasive treatment option with minimal side effects.
Researchers have developed an injectable, flexible electrode that can reduce the cost of neuromodulation therapy, increase its reliability and make it less invasive. The 'injectrode' uses a liquid that cures in the body to create a wired contact, allowing for more elasticity and flexibility compared to traditional rigid implants.
A clinical trial published in Appetite found that transcranial direct current stimulation (tDCS) can reduce or increase appetite depending on a patient's genetic profile. The study used a current of 2 milliamperes and 17 thirty-minute sessions over a month, with participants monitored for six months.
The UAB clinic has achieved rapid accessibility and improved seizure control for patients with drug-resistant epilepsy. Vagal nerve stimulation (VNS) and responsive neurostimulation (RNS) therapies have shown promise, with 12-11 out of 27-16 patients experiencing a 60% reduction in seizures.
The 2019 International Brain Stimulation Award recognizes Mark Hallett's pioneering work in developing transcranial magnetic stimulation (TMS) and advancing the field of neuromodulation. His research has led to new treatments for neurological and psychiatric conditions, including depression and OCD.
Researchers at UT Southwestern Medical Center have made a breakthrough in treating autistic children with neuromodulation, which restored social impairments. The study found that stimulating a specific part of the cerebellum improved social behaviors in both mice and humans, offering new hope for autism treatment.
A multi-disciplinary team of researchers has received a $9 million grant to develop enhanced infrared light technology for treating diseases such as cardiac arrhythmias, high blood pressure, asthma, and diarrhea. The technology aims to stimulate or inhibit electrical signals in the nervous system with laser precision.
Dr. Michael Stanton-Hicks is a pioneer in the management of complex regional pain syndrome (CRPS), with extensive contributions to neurostimulation and chronic pain research. He has bridged advances in neurostimulation, taxonomizing CRPS, and improved patient care through his work at the Cleveland Clinic.
Six abstracts selected for their innovative therapy approaches and basic research providing knowledge to improve treatment or clarify mode of action. These include a new functional treatment for chronic low back pain and stimulation effects on postural instability in Parkinson's disease.
Several emerging companies are developing innovative neuromodulation therapies to alleviate conditions such as autism spectrum disorder, spinal cord injury, and persistent pain. BioInduction Ltd.'s Picostim and BlueWind Medical's RENOVA iStim aim to provide targeted stimulation for various clinical indications.
A new study compares Botox to sacral neuromodulation as treatments for urge incontinence, finding that Botox provides more daily relief but may be associated with more adverse events. The study analyzed data from 381 women and found a significant reduction in symptoms with botulinum toxin.
Dr. Barker's groundbreaking research on transcranial magnetic stimulation (TMS) has revolutionized the field of neuroscience, enabling precise and pain-free brain stimulation. His invention has opened up new avenues for understanding brain function and treating neurological and psychiatric conditions.
Yevgenia Kozorovitskiy, a Northwestern University neurobiologist, has been awarded a $750,000 Beckman Young Investigator grant to discover how chemical neuromodulatory systems work together to support complex behaviors. The award supports her research on using optical microscopy techniques and classical neuroscience technologies.
Researchers at Berkeley Lab found that proper copper levels modulate spontaneous neural activity in developing circuits, which is critical for brain health and development. The study highlights the importance of managing copper levels to prevent misregulation of signaling in cell-to-cell communications.
A new robot technology called RP-7 enables remote presence in programming brain and spine stimulators, allowing non-expert nurses to be guided by specialists. The study found no significant difference in accuracy or clinical outcomes between remote-presence and conventional programming.
A new study published in Archives of General Psychiatry found that deep brain stimulation is a safe and effective intervention for treatment-resistant depression in patients with unipolar and bipolar disorders. After four weeks of single-blind stimulation, 58% of patients achieved remission and showed significant improvement in function.
Researchers have produced a comprehensive guide for using low-intensity, pulsed ultrasound to non-invasively stimulate brain circuits. The approach holds promise for treating life-threatening epileptic seizures and has been shown to be effective in animal studies.
Researchers found that subliminal words can produce a priming effect, where subjects respond faster on tasks related to either the visual or auditory word. TMS applied to specific brain areas disrupted this priming effect, demonstrating top-down processing of subliminal information.
A new neurostimulation system uses continuous electric field adjustments to provide real-time, dynamic paresthesia steering for improved pain relief. This innovative technology enables up to 71 combinations of stimulation settings, leading to enhanced therapeutic possibilities.