Synaptic Failure | Topics

Articles tagged with Synaptic Failure

Discovery shines light on a cascade of events that occurs when toxic tau impacts synapses, suggesting new mechanisms for neurodegeneration

Researchers developed a new tool to track changes in the synaptic proteome over time, correlating changes to synaptic dysregulation and synapse loss. The results suggest that toxic tau oligomers impact postsynaptic structures first, leading to a dynamic cascade of events that contribute to neurodegeneration.

SourceBuck Institute for Research on Aging·JournalMolecular Neurodegeneration·TypeExperimental study·DateJan 28, 2026

Aging | Isoform-specific AMPK repression affects cognitive function in aged mice

Researchers found that suppressing AMPKα1 but not AMPKα2 isoforms improved aging-related impairments in mice. The study revealed novel insights into the roles of AMPK signaling pathway in cognitive aging.

SourceImpact Journals LLC·JournalAging-US·TypeExperimental study·DateMar 7, 2023

Eating sea squirts may reverse the signs of ageing, study shows

A new study suggests that supplementing a diet with Ascidiacea, also known as sea squirts, reverses some main signs of aging in animal models. The researchers found that plasmalogens, vital to body processes, decrease with age and contribute to neurodegenerative diseases like Alzheimer's and Parkinson's.

SourceXi'an Jiaotong-Liverpool University·JournalFrontiers in Molecular Biosciences·TypeExperimental study·DateMay 9, 2022

Davis Instruments Vantage Pro2 Weather Station

Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.