Researchers at CNIO have developed a gene therapy that reactivates the telomerase gene only in the heart of adult mice, resulting in increased survival rates and regeneration of cardiomyocytes. This study provides proof-of-concept for treating chronic and acute heart failure and opens new avenues for age-related diseases.
SourceCentro Nacional de Investigaciones Oncológicas (CNIO)·JournalNature Communications·DateDec 18, 2014
A nearly complete 9,300-year-old frozen bison mummy was recently uncovered in Eastern Siberia. The Yukagir bison mummy has a preserved brain, heart, blood vessels, and digestive system, providing valuable insights into the biology of the species at the end of the Ice Age.
SourceSociety of Vertebrate Paleontology·DateNov 6, 2014
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
A new study by the Montreal Heart Institute found that high doses of fish oil supplements do not reduce atrial fibrillation, a common type of irregular heartbeat. The study also showed that fish oil supplements did not reduce inflammation or oxidative stress markers, which may explain their lack of efficacy.
SourceMontreal Heart Institute·JournalJournal of the American College of Cardiology·DateOct 14, 2014
Researchers at NYU Langone Medical Center have identified a protein known as Pcp4 as a regulator of the heart's rhythm in mouse models. Disruption of the Pcp4 gene leads to ventricular arrhythmias and increased mortality. The study suggests that targeting Pcp4 could lead to new treatments for arrhythmias.
SourceNYU Langone Health / NYU Grossman School of Medicine·JournalJournal of Clinical Investigation·DateOct 8, 2014
Researchers discovered that naked mole rats maintain youthful heart function until age 90, offering insights into preventing debilitating cardiovascular disease. The rodents' natural habitat and stress resistance may hold the key to understanding these protective mechanisms.
SourceUniversity of Texas Health Science Center at San Antonio·DateAug 18, 2014
Researchers at the Max Planck Institute of Molecular Cell Biology and Genetics have developed a method to capture detailed three-dimensional images of cardiac dynamics in zebrafish. By combining high-speed Selective Plane Illumination Microscopy and clever image processing, they reconstructed multi-view movie stacks of the beating heart.
SourceMax-Planck-Gesellschaft·JournalNature Methods·DateJul 23, 2014
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Researchers have developed a minimally invasive gene therapy procedure that transforms ordinary heart muscle cells into specialized 'biological pacemaker' cells. This breakthrough could lead to a long-lasting treatment for patients with heart rhythm disorders, potentially eliminating the need for electronic pacemakers.
SourceCedars-Sinai Medical Center·JournalScience Translational Medicine·DateJul 16, 2014
A new study has found that BPS, a common chemical substitute for BPA, can cause disruptions to female heart rhythms. The research suggests that BPS, like its BPA counterpart, interferes with hormone regulation and causes abnormal calcium handling in cardiac muscle cells.
Researchers found that heart muscle cells in mice undergo a brief proliferative burst prior to adolescence, increasing in number by about 40% to meet the body's growing needs. This discovery suggests that thyroid hormone therapy could stimulate this process, enhancing the heart's ability to regenerate in patients with heart disease.
New research by UT Southwestern Medical Center discovered that high levels of oxygen in the postnatal environment result in cell cycle arrest of cardiomyocytes, making it impossible for adult hearts to regenerate. The study's findings have significant implications for cardiovascular medicine and may lead to new therapeutic approaches.
SourceUT Southwestern Medical Center·JournalCell·DateApr 24, 2014
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
The American Association of Anatomists announced its 2014 award winners, including Jeffrey Laitman for his work in human anatomy education and Drew Noden for his scientific achievements. The winners will receive medals, plaques, and honorariums, as well as opportunities to present lectures at the 2014 Annual Meeting at Experimental Bio...
A recent study published in Stem Cell Reports has found no evidence of complete heart regeneration in newborn mice after apex resection. The researchers, led by Ditte Andersen, were unable to replicate the findings of a previous 2011 study that suggested complete regeneration was possible.
SourceCell Press·JournalStem Cell Reports·DateApr 3, 2014
Crude oil interferes with fish heart cells, causing slowed heart rate, reduced cardiac contractility, and irregular heartbeats. The study reveals that oil blocks potassium channels, increasing the time to restart the heart on every beat, ultimately slowing the heartbeat.
Fossil evidence reveals the step-by-step assembly of the face during the evolutionary transition from jawless to jawed vertebrates. The Romundina skull shows primitive and modern features, shedding light on the origin of the jawed vertebrate face.
Researchers discovered a modified pacemaker-like enzyme, GSK-3 beta, that mimics CRT's biological effects on heart muscle cells. This breakthrough could lead to new treatments for heart failure patients who don't qualify for traditional CRT therapy.
SourceJohns Hopkins Medicine·JournalJournal of Clinical Investigation·DateDec 2, 2013
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A recent study by University of Michigan researchers has found that sturgeon have evolved at an incredible rate in terms of body size, with some species reaching sizes comparable to those of Volkswagen vans. This discovery challenges the common perception of sturgeon as 'living fossils' and sheds new light on the evolutionary process.
SourceUniversity of Michigan·JournalNature Communications·DateJun 6, 2013
A study reveals why Puerto Rican lizards don't rapidly extend their dewlaps like Jamaican cousins, instead using alternative strategies to enhance detection of displays. The research shows the island's species lacks physiology for rapid movement, relying on tailoring speed and duration of displays to match forest conditions.
SourceUniversity of New South Wales·JournalFunctional Ecology·DateJun 3, 2013
Scientists have found that certain omega-3 and omega-6 fatty acids regulate the cardiac function of hibernating animals, ensuring a regular heartbeat. Hibernators show higher levels of these fatty acids in their heart tissue compared to non-hibernating animals.
SourceUniversity of Veterinary Medicine -- Vienna·JournalPLOS ONE·DateMay 7, 2013
Dr. Lawrence Witmer's Visible Interactive Dinosaur (VID) project aims to digitally recreate the tissues stripped away by time, creating the most realistic dinosaur renderings. The project has dual purpose of helping paleontologists and educating the public about physiology and anatomy.
SourceFederation of American Societies for Experimental Biology·DateApr 22, 2013
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
A specific gene called Meis1 regulates the heart's ability to regenerate after injuries. The study found that deleting this gene extended the proliferation period in newborn mice and re-activated regeneration in adult mouse hearts without harming cardiac functions.
SourceUT Southwestern Medical Center·JournalNature·DateApr 17, 2013
Researchers found that blocking an enzyme promoting inflammation can prevent cardiac tissue damage and fibrosis after a heart attack. The study's results show improved cardiac function and reduced inflammatory factors in mice treated with the compound.
SourceUniversity of California - Davis Health·JournalProceedings of the National Academy of Sciences·DateMar 21, 2013
UT Southwestern researchers identified microRNA miR-15 as a regulator of the heart's ability to regenerate, with potential therapeutic applications. By understanding this molecular mechanism, scientists may be able to control the heart's regenerative process and develop new treatments for cardiovascular disease.
SourceUT Southwestern Medical Center·JournalProceedings of the National Academy of Sciences·DateDec 20, 2012
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Researchers have identified previously unseen anatomy preserved in fossils using synchrotron-based imaging techniques. The study reveals that a 50 million-year-old lizard skin contains teeth, changing the understanding of this fossil animal.
SourceUniversity of Manchester·JournalApplied Physics A·DateDec 18, 2012
A team of researchers at Brigham and Women's Hospital used innovative technology to identify the origins of new cardiac cells. They found that these cells primarily arose from existing heart muscle cells, rather than stem cells, in a process that may be limited by age.
SourceBrigham and Women's Hospital·JournalNature·DateDec 5, 2012
Recent research revealed mosquitoes possess surprisingly effective immune systems, destroying pathogens by utilizing the circulatory system's unique characteristics. A Vanderbilt study discovered a new mechanism for eliminating pathogens, increasing effectiveness in disease control strategies.
SourceVanderbilt University·JournalPLOS Pathogens·DateNov 29, 2012
Scientists have developed a technology to visualize how circulating blood affects the developing heart, potentially uncovering triggers for heart defects. The study maps shear stress on the endothelial cells lining the growing heart, which has been linked to gene expression changes and defect formation.
SourceCase Western Reserve University·JournalBiomedical Optics Express·DateOct 30, 2012
A 520-million-year-old fossilized arthropod has revealed a remarkably well-preserved brain structure, challenging the long-standing debate on the origin of insects. The discovery suggests that complex brains evolved earlier than previously thought and have changed little over time.
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
A study published in Diabetes found that exercise benefits diabetic hearts by improving energy exchange and resisting oxidative stress. Fatty acids, previously thought to be detrimental, were shown to improve heart function when the heart needs to beat faster.
SourceJohns Hopkins Medicine·JournalDiabetes·DateJul 17, 2012
Researchers have identified a genetic variant in a cardiac protein that increases the risk of heart rhythm dysfunction and sudden death in patients with dilated cardiomyopathy. The variant, known as Ser96Ala, affects calcium regulation in heart cells, leading to arrhythmias and increased mortality.
A small number of cells in the embryo are enough to form the outer layer of pumping heart muscle in an adult zebrafish. The researchers discovered that only eight single cells contributed to forming a major type of heart muscle, and just one or two cells could create up to 70% of the entire ventricular surface.
SourceDuke University Medical Center·JournalNature·DateApr 25, 2012
Gladstone scientists have made a groundbreaking medical breakthrough in mice, transforming scar-forming cardiac cells into beating heart muscle. The research may have broad human-health implications and could provide an innovative alternative to heart transplants.
A new study published in The Anatomical Record reveals that some baleen whales have specialized fats associated with their jaws, similar to those found in toothed whales. This discovery sheds light on the auditory anatomy of these animals and challenges previous assumptions about their hearing systems.
SourceWoods Hole Oceanographic Institution·JournalThe Anatomical Record·DateApr 17, 2012
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
Researchers found that hibernating woodchucks have a higher resistance to cardiac arrhythmias due to their unique calcium handling properties. This insight may suggest new strategies for protecting non-hibernating animals from fatal cardiac arrhythmias induced by hypothermic stresses and myocardial ischemia.
Researchers found that scarring after a heart attack can help prevent further damage, but interrupting the process weakens heart function. The study suggests that timing is essential in manipulating cells to decrease scarring and enhance regeneration.
SourceUniversity of North Carolina Health Care·JournalThe EMBO Journal·DateNov 15, 2011
Researchers at the University at Buffalo have developed a new approach to regenerating heart muscle cells. By infusing cardiosphere-derived cells into coronary arteries, they were able to increase healthy heart muscle cells by 30% within a month.
Biologists have identified two critical genes, DSCAM and COL6A2, responsible for congenital heart defects in individuals with Down syndrome. These genes disrupt cardiac development and function when produced at elevated levels. The study used a novel approach combining fruit flies and mice to untangle the problem.
SourceUniversity of California - San Diego·JournalPLOS Genetics·DateNov 3, 2011
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
Researchers identified three fatty acids involved in Burmese pythons' extreme heart growth after large meals. These fatty acids may trigger healthy physiological cardiac hypertrophy in diseased human hearts.
SourceUniversity of Alabama in Tuscaloosa·JournalScience·DateOct 27, 2011
Researchers at Johns Hopkins Medicine found that a widely used pacemaker for heart failure works by raising regulator of G-protein-signaling proteins in the heart. This helps restore balance between two proteins, allowing the heart muscle to respond to hormones like adrenaline more effectively.
SourceJohns Hopkins Medicine·JournalScience Translational Medicine·DateSep 14, 2011
Researchers found that mice without the HDAC3 enzyme experience rapid thickening of the heart muscle and heart failure on a high-fat diet. This molecular link has implications for people on Western diets and combating heart disease.
SourceUniversity of Pennsylvania School of Medicine·JournalJournal of Biological Chemistry·DateSep 12, 2011
Researchers at UCLA have found that adult human cardiac myocytes lose their ability to proliferate due to their primitive state being incompatible with proper heart function. This knowledge could lead to reprogramming a patient's own cardiac myocytes to replace damaged heart muscle, potentially revolutionizing treatments for heart cond...
SourceUniversity of California - Los Angeles Health Sciences·JournalJournal of Cell Biology·DateAug 8, 2011
The Gray's Anatomy for Students App is a clinically-oriented textbook for human anatomy, featuring over 1,000-color illustrations and various interactive features. The app provides access to the latest edition of Gray's Anatomy for Students, Second Edition, with updates from a team of authors and an international advisory board.
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Researchers at U-M found that mutations caused by aging or disease can lead to a loss of cell identity, resulting in gene expression changes. This instability can have significant impacts on physiological functions, including arrhythmia in mice.
SourceMichigan Medicine - University of Michigan·JournalJournal of Clinical Investigation·DateJul 1, 2011
Researchers analyzed the heads of pachycephalosaur dinosaurs and compared them to modern animals that engage in head butting. They found that the bony anatomy of pachycephalosaur domes is better at protecting the brain than in any modern head-butting animal.
SourceUniversity of Calgary·JournalPLOS ONE·DateJun 28, 2011
The European Society of Cardiology recommends redefining cardiac hypertrophy as myocardial remodelling to account for changes in non-myocyte cells and cell division. This change aims to improve communication among researchers and clinicians, leading to better risk stratification and treatment.
SourceEuropean Society of Cardiology·JournalEuropean Journal of Heart Failure·DateJun 26, 2011
A 47 million-year-old lizard fossil has provided key findings on the evolutionary relationships between snakes and other reptiles. The study reveals that snakes evolved independently from limbless lizards, rather than sharing a common ancestry with burrowing reptiles.
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Research suggests that a balanced diet with mono- and polyunsaturated fats can improve cardiac function in patients with heart failure. By providing sufficient energy to the heart, a damaged heart can maintain its normal metabolic profile and utilize its preferred energy source.
Researchers at UT Southwestern Medical Center discovered that newborn hearts can heal themselves completely. Within three weeks of removing a portion of the heart, it was able to grow back the lost tissue and function like a normal heart. This breakthrough offers new possibilities for treating heart disease.
SourceUT Southwestern Medical Center·JournalScience·DateFeb 24, 2011
Anthropologist Jane Desmond explores how Body Worlds exhibits tolerate the public display of human corpses, idealizing them as objects of scientific curiosity. The exhibitors promote the display as an advancement in anatomy studies, using de-emotional screens and depersonalization to create a universal experience.
SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalConfigurations·DateFeb 7, 2011
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
A study by University of Illinois Chicago researchers found that certain strains of Listeria monocytogenes can invade the heart, leading to serious and difficult-to-treat cardiac infections. The bacteria display modified proteins that enable easier entry into cardiac cells, making them a new target for treatment.
SourceUniversity of Illinois Chicago·JournalJournal of Molecular Microbiology and Biotechnology·DateJan 26, 2011
Researchers at Sanford-Burnham Medical Research Institute have discovered a genetic mechanism that causes lipotoxic cardiomyopathy independently of a diet high in fat. The study found that an imbalance in cellular fats can lead to heart problems, and targeting the SREBP protein may help prevent these issues.
SourceSanford Burnham Prebys·JournalGenes & Development·DateJan 18, 2011
Researchers found Longevinex, a resveratrol supplement, provides cardio-protection across a wide dosage range without toxic effects. Unlike plain resveratrol, Longevinex exhibits an L-shaped safety curve, minimizing heart damage and optimizing protection.
SourceResveratrol Partners LLC, dba LONGEVINEX·DateDec 29, 2010
Researchers are developing a robotic system that combines real-time magnetic resonance imaging (MRI) with a highly flexible robotic device to perform cardiothoracic surgeries on beating hearts. This minimally invasive approach aims to increase precision and reduce trauma, leading to faster recovery times.
Dr. Arjun Deb received the prestigious Louis N. and Arnold M. Katz Basic Science Research Prize for his groundbreaking research on Wnt1-mediated dynamic injury response in epicardium activation and mammalian cardiac repair. His work has significant implications for understanding adult stem cell biology and organ regeneration.
SourceUniversity of North Carolina Health Care·DateNov 30, 2010
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
Researchers at the University of Cincinnati have identified a protein called HAX-1 that protects cardiac cells and muscle from damage during ischemia-reperfusion injury. The study found that HAX-1 levels were reduced in hearts after heart attack, but overproduction improved contractile performance and decreased cell death.
Researchers at the University of Cincinnati have developed a stem cell-infused patch that promotes cell migration to damaged cardiac tissue following a heart attack, resulting in improved function. The patch combines cardiomyocytes, endothelial cells, and embryonic fibroblasts to enhance regeneration of heart tissues.
A study of nearly 50,000 people has identified DNA sequence variations associated with cardiac electrical activity, which may lead to novel approaches to prevent or treat serious rhythm disorders. The findings provide new clues about the biologic pathways that influence cardiac conduction and identify genes and genetic pathways involve...
SourceNYU Langone Health / NYU Grossman School of Medicine·JournalNature Genetics·DateNov 14, 2010
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
A fluorescent image of the mosquito heart, taken by Vanderbilt graduate student Jonas King, has won first place in Nikon's 'Small World' 2010 photomicrography competition. The image showcases the unique structure and function of the mosquito's circulatory system.
Researchers found cardiac damage in mice exposed to low-dose sarin, including left ventricular dilation and prolonged ventricular repolarization. The study suggests a potential link between low-dose chemical warfare agent exposure and long-lasting heart problems.
Researchers used rotting fish to understand the decomposition process, shedding light on soft-bodied creatures that existed 500 million years ago. The findings have improved the accuracy of fossil reconstructions, allowing scientists to better place early vertebrates on the evolutionary timeline.
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
A team of researchers at UC San Diego will study the impact of low oxygen levels on cells and tissue in the heart, lung, and brain. The study aims to understand molecular mechanisms that contribute to low oxygen tolerance or susceptibility in diseases such as stroke and pulmonary hypertension.