Articles tagged with Brain
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Dr. Hyungbae Kwon of Max Planck Florida Institute has received a $6.8 million Pioneer Award to study neuromodulators using light, aiming to understand internal brain state and its effects on sensation, perception, and cognition. The grant will help develop novel optogenetic approaches to dissect animal sensations and behaviors at highe...
A new mathematical model describes the distribution of sensory errors in learning, revealing that animals explore and track a range of possibilities to compensate for variabilities. The study found that birds combine their hypotheses with new information from their ears while singing, surprisingly accurately.
A new study demonstrates how visual cortex neurons learn to recognize familiar faces regardless of their location. Participants who reported stronger familiarity with peers more consistently recognized the other individual in different parts of their visual field.
A study using machine learning and data from 550 children with varying learning difficulties identified four clusters of cognitive challenges that did not match previous diagnoses. The researchers found that working memory and phonological skills deficits often overlap, affecting both reading and math abilities.
A study found that infants' responsiveness to fearful faces at 7 months predicts altruistic behavior in toddlerhood. Additionally, brain responses in the dorsolateral prefrontal cortex are linked to this early precursor of prosocial behavior.
Researchers developed targeted plasticity therapy (TPT) to pair physical movements with vagus nerve stimulation, accelerating brain reorganization and recovery. The study found TPT to be twice as effective as traditional rehabilitation alone in doubling upper limb recovery rates.
A study by Massachusetts General Hospital researchers found elevated glial activation in the brains of fibromyalgia patients, correlating with fatigue levels. The results suggest that neuroinflammation may be a potential treatment target for the condition.
The Child Mind Institute and international researchers have released open-source non-human primate brain imaging data sets. These aggregated datasets will help accelerate the development of 'wiring diagrams' that may improve understanding of brain disorders. The goal is to advance research on mental health and learning disorders.
Researchers create a new model for collective behavior within the brain, bridging the gap between EEG waves and random fluctuations. The technique has potential to reduce stress and onset of conditions like PTSD in military personnel.
Researchers found specific physical changes to axons speed up neural transmission, leading to higher cognitive abilities. Axon myelination increased significantly during adolescence, corresponding with a dramatic increase in signal conduction velocity.
A University of Iowa-led research team identified a brain marker associated with aggression in toddlers, including smaller P3 brain waves accompanying tone changes. This finding could help diagnose aggressive behavior in young children before it becomes ingrained.
Researchers created a way to measure different types of fear of falling (FOF) in Parkinson's patients, highlighting the importance of cognitive function. The study aims to improve treatment and quality of life for patients with FOF.
A UCI research team found that brain endothelial cells can engulf and deposit red blood cells outside of blood vessels without a blood vessel tear. This discovery could lead to new efforts to eliminate brain bleeding and its consequences.
The ALTA-1 trial found brigatinib to be a first-line treatment option for advanced ALK-positive non-small cell lung cancer, with a 51% reduction in progression or death risk compared to crizotinib. Patients treated with brigatinib also showed improved response rates and longer progression-free survival.
Recent advances in EEG technology could enable earlier diagnoses of common mental and neurological disorders like autism and dementia. Non-invasive portable devices make functional brain measurement possible during primary care check-ups.
Experts emphasize the need for more neuroscience research on long-term recovery from substance abuse, citing the potential benefits for clinical practice and public policy. The International Quit & Recovery Registry provides valuable insights into recovery processes.
Researchers propose using blood-brain barrier breakdown as an early warning sign for Alzheimer's disease, which could lead to earlier diagnosis and treatment. Healthy blood vessels are crucial for normal brain functioning, and damage can be detected with imaging tests such as MRI.
Researchers connected cognitive science's Universal Law of Generalization to information theory, revealing that the brain approaches optimal performance in perception and memory. This discovery has implications for education, particularly in STEM fields, where students learn to differentiate between complex stimuli.
A vicious feedback loop drives brain degeneration in Alzheimer's disease, but a clinically approved drug may provide a solution. The study identified Dkk1 as a central player in the cycle, and targeting it with fasudil shows promise in animal models.
Research suggests that even low levels of physical activity, such as walking at least four hours a week, may reduce the severity of a stroke. The study found that people who engaged in light to moderate physical activity were twice as likely to have a mild stroke than those who were physically inactive.
A study published in Neuropsychologia suggests that human brains are innately attracted to sedentary behaviors and must work harder to avoid them. The research found that participants were faster at moving towards active images but required more brain resources to move away from inactive images.
Researchers at Duke University discovered a neural circuit that enables the brain to predict motion based on past experiences and sensory inputs, mirroring Bayesian statistical inference. This discovery could improve our understanding of motor control and eye movements.
The MoreGrasp project developed a sensoric grasp neuroprosthesis controlled by thought, enabling users to perform daily activities with ease. The technique uses 'attempted movement' signals, allowing for more precise control and improved learning through brain-computer interface training.
In low light, retinal cells sensitive to upward movement change their behavior, firing on detecting any kind of movement. This adaptability helps the brain sense movement and may aid in designing implantable retinal prosthetics.
A new study published in the Journal of Cognitive Neuroscience suggests that our brains prioritize character development when listening to or viewing a story. This study used fMRI scans to examine how participants conveyed narrative ideas through different forms of expression, such as speech, gestures, and drawings.
A new study from the University of Illinois found that dietary fiber can reduce brain inflammation in old mice, leading to improved memory and reduced cognitive decline. The researchers discovered that high-fiber diets elevated butyrate levels in the blood, which had anti-inflammatory properties on microglia.
A study by UC Riverside researchers found that male mice on high-fat diets experienced neuroinflammation and reduced testosterone levels, while female mice remained protected. The findings suggest ovarian estrogen plays a crucial role in protecting females against weight gain and associated health issues.
Scientists have uncovered how mice ignore their own footsteps, offering insights into human speech and music learning. The study shows that mice develop an adjustable sensory filter to suppress movement-related sounds, improving sound detection in their environment.
Researchers found that fruit flies freeze in response to threats at slow walking speeds, but run away when moving quickly. The team identified a single pair of neurons critical for this process, providing insights into the brain's defensive strategies.
Researchers found that brain anatomy and psychological traits can predict which patients will respond to sugar pills, resulting in reduced pain and cost savings. The study suggests that clinicians should consider prescribing sugar pills for chronic pain patients, potentially opening up a new field.
The National Science Foundation has awarded $16 million to 18 cross-disciplinary projects exploring the intersection of neural and cognitive systems. These innovative research approaches aim to tackle fundamental questions about the brain, developing new methods for studying neural activity and behavior.
A study by Gemma Scholes and colleagues found that newborn babies with congenital heart disease tend to have significantly enlarged kidneys. This contradicts previous assumptions about organ development in these infants. The type of congenital abnormality also influences kidney size, with some having larger or smaller than normal kidneys.
Researchers found that clots have different compositions and administering tPA can be as effective as thrombectomy given sufficient time. The study involved nearly 600 patients across five countries and provided definitive evidence on the value of giving patients tPA.
Bilingual individuals exhibit unique brain activity when switching between languages, with increased cognitive control activity during disengagement. In contrast, engaging in a new language comes relatively cost-free from a neurobiological standpoint, suggesting that the burden of language-switching lies in disengagement.
A study found that brain teaser questions give interviewers power and speak to their dark personality traits, such as narcissism and sadistic tendencies. Participants who support the use of these questions were less socially competent and relied heavily on intuition in the hiring process.
Researchers found neural dynamics predict future speech timing based on past speech rate, influencing word comprehension. The study suggests that brain activity synchronizes to speech rhythms, affecting how we process and hear words.
Researchers from the German Primate Center found that visual attention desynchronizes nerve cell activity, enabling more complex information processing. This insight may provide evidence for mechanisms underlying ADHD and autism, and sheds light on how the brain processes stimuli.
A recent study from Prof. Gaiti Hasan's lab has identified the FMRFa receptor as a crucial molecule in sustaining flight in fruit flies for long periods of time. The receptor is part of a class of proteins known as GPCRs, which help convert extracellular messages into cellular responses.
A study published in Neurology found that medical marijuana, specifically THC, reduces connections between brain areas processing emotions and sensory signals, providing pain relief for radicular nerve pain. The more pain relief experienced, the greater the reduction of these brain connections.
Researchers will use mice to create detailed maps of young and aging brains' blood vessels, hoping to understand healthy brain development and disease progression. The project aims to lay the groundwork for studying pathological conditions like strokes and Alzheimer's disease.
Researchers at Max Delbrück Center for Molecular Medicine found significant differences in male and female mice microglia structure and function. Male microglia are more active and respond differently to injury, but may also be less protected against environmental insults.
A new study aims to tailor behavioral therapy for co-occurring depression and obesity by analyzing how the brain responds to the intervention. The researchers will adapt an integrated behavioral therapy to target changes in brain function and health behaviors associated with better weight loss and depression outcomes.
A George Mason University researcher has been awarded a $2.5 million grant to develop remedies for the Venezuelan equine encephalitis virus (VEEV), which can cause long-term neurological problems and even death. The team aims to identify specific targets for therapeutic countermeasures and prevent the disease in mouse models.
A recent study reveals that Zika virus proteins bind to cellular proteins essential for neural development, leading to brain damage and microcephaly. The research identifies specific viral factors responsible for the condition, offering new insights into the virus's mechanism of action.
Beston's research focuses on the ecological drivers of eye and brain size evolution in a species of fish, with funding from the AAUW. Her work reveals that increased predation is associated with smaller eye sizes, while larger eye sizes are correlated with improved vision and fitness benefits.
Researchers will examine connections between cardiovascular disease and brain health in a 3,000-participant study. The study aims to determine whether heart health explains increased incidence of Alzheimer's disease among different racial and ethnic groups.
A phase 2 trial conducted by Cleveland Clinic shows that ibudilast decreased progression of brain atrophy in progressive MS patients by 48 percent versus placebo. The study also demonstrated the utility of advanced imaging in clinical trials to measure the impact of therapies on brain health.
A $3.8 million NIMH grant will support the development of a predictive model that uses machine learning techniques to identify neural signatures of suicidal ideation and behavior. This technology has the potential to improve clinicians' ability to detect and treat suicidal patients, reducing suicide risk among young adults in the US.
A newly discovered mammal fossil contains fossils of 38 babies, providing insight into the evolution of mammals' reproductive strategies. The discovery suggests that a key development in mammalian evolution was trading brood power for brain power.
A new platform called INSiGHT was used to examine over 100 genes in the retina, identifying 16 key retinal regulatory genes. Of these, 15 were previously unknown and nine have been linked to human diseases.
A new study from Binghamton University suggests that women's diets play a bigger role in their emotional wellbeing than men's. Women are less likely to experience mental distress until they follow a balanced diet and healthy lifestyle.
A new study explores the cognitive effects of childhood acute lymphoblastic leukemia (ALL) and its treatment on brain function. The research reveals that connectome disruption is associated with delayed neurodevelopment in long-term survivors, with younger age at diagnosis and longer chemotherapy duration linked to poorer outcomes.
Researchers discovered a predictive biomarker for epilepsy by analyzing the connection between heartbeat irregularities and abnormal brain activity in mice. They found that anomalous heart rate patterns slightly preceded abnormal brain waves, allowing them to predict which mice would develop seizures with 100% accuracy.
Researchers discovered a brain-heart biomarker that can identify mice at risk of developing post-cerebral malaria epilepsy. This finding could translate to humans and improve therapeutic approaches for patients recovering from traumatic brain injury or stroke, which are estimated to develop epilepsy in up to 15 percent of survivors.
Researchers study how male fruit flies generate their courtship song using cutting-edge imaging techniques and genetic tools. They discover that the song serves as an honest signal of a male's fitness, with flaws indicating neuromuscular deficits, which can affect flying abilities.
Researchers developed a handheld ophthalmology instrument with adaptive optics technology to image individual photoreceptors in the eye, improving diagnosis of eye diseases. The device can capture images of tiny photoreceptors close to the center of the retina, providing insights into brain-related diseases and trauma.
The study reviews the psychology behind rapid spending decisions and proposes five policy options to optimize retirement income solutions. These include financial literacy programs, safe automatic options, precommitment plans, disclosures and framing, and customized interventions.
A recent study published in Nature Communications found that variability in neural responses is not just random noise, but rather due to fluctuations in internally generated signals like attention. This discovery has significant implications for understanding how our brains work and focus, potentially leading to diagnostic tools for ne...
A study published in Cell describes the discovery of a molecular link between aging and two major genetic causes of neurodegenerative diseases, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The findings reveal possible new targets for treatment and highlight the need for a better understanding of the biology of...
A clinical trial found that combination immunotherapy reduced melanoma brain metastases by 26% in 94 patients. The treatment, combining checkpoint inhibitors ipilimumab and nivolumab, also showed durable responses with 59.5% of patients remaining progression-free at nine months.