Articles tagged with Brain
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A study found that the general public's limited understanding of human anatomy can impact the success of health screening campaigns targeting specific organs. The research revealed a surprising eagerness among the public to learn about anatomy, despite their knowledge gaps.
Current RECIST guidelines face challenges in measuring cancer response with emerging targeted therapies. Researchers propose a new baseline approach to track stability and separate tumor burden from treated areas.
Researchers will study the effects of a multicultural healthy diet rich in anti-inflammatory foods on cognitive function and inflammation. The study aims to assess whether this diet can reduce cognitive decline and Alzheimer's disease risk in middle-aged and older participants.
Researchers found that babies prefer to look at the likely option when it is easier to distinguish, but not when the difference is smaller. Six-month-old babies can also estimate which color makes up the majority of balls and choose accordingly.
Researchers have discovered brain circuitry essential for alertness and brain states in zebra fish and mice, suggesting the human brain is likely similarly wired. The study used a molecular method to identify six suspect circuits composed of distinct populations of neurons that modulate neuronal activity.
A new study published in the Journal of Leukocyte Biology has identified a novel therapeutic target to reduce brain inflammation in diseases like multiple sclerosis and Parkinson's. Mature monocytes have been found to express CXCR7 receptor on their surface, which may be used to block inflammation and HIV infection in the brain.
The Brain & Behavior Research Foundation has awarded over $13.6 million in Young Investigator Grants to 196 promising young scientists, supporting innovative research into psychiatric disorders affecting one in five people. The grants aim to identify causes, improve treatments and develop prevention strategies for conditions like addic...
A study published in the Journal of Neuroscience suggests that low oxygen levels, not limited blood flow, cause preterm brain cells to fail normal development. This finding opens up opportunities to restore oxygen loss and potentially reduce life-long impacts of preterm brain injury.
Researchers found bees display unique biases in left- and right-handedness when flying through obstacles, impacting flight efficiency. This discovery could lead to strategies for steering drone aircraft fleets, optimizing safe and collision-free routes.
The study reveals that β-amyloid accumulation occurs in the inner parts of the brain within the default mode network. This finding holds significant implications for future research studies and clinical diagnosis of Alzheimer's disease.
A new approach to detecting dyslexia has been developed by associating auditory processing in children with their reading skills. The study found that children who had difficulty processing low-frequency sounds were more likely to have reading problems and may be at risk of developing dyslexia.
Researchers will examine patients' and family members' perspectives on personality changes before and after Parkinson's disease treatment. The study aims to develop personalized measures of personality and inform public discussions of identity and autonomy in the context of deep brain stimulation.
A recent study by Maastricht University Medical Center and Maastricht University found that a specific enzyme, NOX4, plays a crucial role in the brain's sensitivity to hypoxia. This discovery has significant implications for treating post-stroke brain damage.
A recent study found that participants with type 2 diabetes who lost weight through lifestyle changes had better blood flow to the brain, suggesting a potential cognitive benefit. The intervention was most effective for individuals who were overweight but not obese.
A new approach identifies concept alterations associated with suicidal ideation and behavior, using machine-learning algorithms to assess neural representation of specific concepts. The study accurately identified 91% of participants with suicidal tendencies, and 94% of those who had attempted suicide.
Researchers at Max Planck Institute discover that female flies become more receptive to courting males when they smell their favorite food. The study found that vinegar odor boosts the perception of a male sex pheromone, increasing the likelihood of mating.
A two-week high-intensity interval training (HIIT) program reduced glucose metabolism in all areas of the brain in physically inactive individuals with prediabetes or type 2 diabetes. HIIT improved whole-body insulin sensitivity, and moderate exercise also showed similar benefits.
Researchers developed software using machine learning to analyze EEG signals from preterm infants, providing an estimate of brain functional maturity. The method is more precise than current methods and enables automatic monitoring of premature infant brain development.
A study by Johns Hopkins University found that pictures of junk food are almost twice as distracting as healthy food images, even when people are focused on a task. The researchers tested this theory with participants who ate candy before completing a computer task.
A recent study published in Psychonomic Bulletin & Review found that calorie-dense foods are more distracting than low-calorie foods or everyday objects, even if they are not related to food. The researchers used a distraction paradigm to test how participants' thoughts and cognition relate to their eating habits.
Researchers found impaired mitochondrial metabolism and increased glycolysis in LOAD cells, indicating failing mitochondria. The study suggests that bioenergetics changes may contribute to the risk and pathophysiology of late-onset Alzheimer's disease.
Researchers at Northeastern University's Center for Complex Network Research have identified fundamental rules for how the brain controls movement in nematode worms. The study provides unprecedented detail on how individual neurons control specific types of locomotion, paving the way for future research into human brain function and ne...
A Lithuanian professor has been awarded the Paper of the Year by The Congress of Neurological Surgeons (CNS) for his groundbreaking research on severe traumatic brain injury. The study found that longer durations of cerebrovascular autoregulation impairment events significantly correlate with worse patient outcomes.
Researchers have found that young hockey players who suffered concussions may still exhibit white matter changes in the brain months after being cleared to return to play. Advanced MRI techniques revealed prolonged abnormalities in terms of brain structure and function, suggesting potential long-term consequences.
A preclinical study suggests a novel mechanism for treating pain without the addictive side effects of current opioid medications. The use of positive allosteric modulators enhances the effect of pain-relief chemicals naturally produced by the body, providing stronger and longer-lasting pain relief.
Stellenbosch University researchers found individuals with PTSD had lower levels of specific bacteria, which may contribute to immune dysregulation and inflammation. The study suggests that gut microbiome changes could be an early response to childhood trauma, increasing the risk of developing PTSD later in life.
The NIH BRAIN Initiative has launched a major effort to discover and catalog the brain's diverse cell types. The BICCN will generate knowledge that is prerequisite to solving the mysteries of brain disorders such as schizophrenia, Alzheimer's disease, and autism spectrum disorder.
Researchers will count and catalog cell types in mouse brain using single-cell transcriptomics, aiming to build a comprehensive atlas of cell types that can be applied to the human brain.
Research reveals sleepwalkers have improved automation in movement control compared to non-sleepwalkers. They maintain speed and accuracy during tasks requiring conscious attention, indicating potential daytime markers for sleepwalking diagnosis.
A new Yale study reveals decreased brain glucose levels in individuals with obesity and type 2 diabetes compared to lean individuals. This finding might explain the underlying mechanisms of disordered eating behavior and an increased risk of Alzheimer's disease among obese and diabetic individuals. The researchers suggest that impaired...
Researchers found that LRRK2 gene mutations cause age-dependent dopaminergic neuron degeneration and impair the autophagy-lysosomal pathway in mice. The study suggests an essential role of LRRK in DA neuron survival and regulation of the autophagy-lysosomal pathway in the aging brain.
The University of Minnesota Medical School's Center for Magnetic Resonance Research has received a NIH R01 grant to investigate the underlying trajectory of brain chemistry in healthy aging and Alzheimer's disease. The project aims to identify abnormal metabolic pathways in Alzheimer's disease.
Researchers identified 'speed neurons' and 'direction neurons' in the bee brain that work together to create a memory for navigation. This ability is crucial for bees, as they rely on it to return to their hive after foraging trips.
Researchers discovered two sets of neural signals control diaphragm movement, one in the brain and one in the spinal cord. They used a drug to activate this alternative pathway, restoring breath-like movements in rodents.
Scientists at Wake Forest Baptist will use a $9.2 million grant to develop new molecularly targeted drugs and drug delivery systems for aggressive brain cancer glioblastoma. The goal is to directly attack tumor mass and cells in surrounding areas, increasing therapeutic efficacy.
Researchers at McLean Hospital discovered a unique brain training program that improves cognitive skills in individuals with bipolar disorder. The study found significant improvements in cognitive performance, memory, and visual learning, with sustained benefits six months after treatment.
A study published in JNeurosci found that chronic exposure to THC may alter inhibitory function in GABA neurons, increasing dopamine levels and promoting addictive qualities. This discovery could lead to a new target for treating cannabis use disorder.
A study published in Brain Stimulation found that transcranial direct current stimulation (tDCS) can improve endurance performance by decreasing perceived effort. The research, conducted at the University of Kent, used a placebo-controlled study to test the effects of tDCS on cycling time to task failure.
Researchers found that abnormalities in the brain's blood-brain barrier may play a critical role in schizophrenia development. This discovery could lead to novel treatment strategies targeting abnormal brain blood vessels, complementing existing treatments.
Researchers have identified a gene that may provide potential therapy for cerebral cavernous malformations (CCMs), a condition characterized by enlarged and irregular blood vessels in the central nervous system. The study suggests using angiogenesis inhibitors, such as TSP1, to treat or prevent CCMs.
Researchers have identified changes in molecular signaling related to neural plasticity, inflammation and neurodegeneration triggered by the psychedelic substance 5-MeO-DMT. This study suggests that classic psychedelics may induce neuroplasticity and exert antidepressant effects.
A Swedish registry study found that dementia patients with stroke can receive thrombolysis treatment without increased risk of brain haemorrhage or death. However, those over 80 may experience worse functional outcomes and be more likely to be discharged to nursing homes.
Scientists at Columbia's Zuckerman Institute found that the brain recalls larger concepts first when recalling information, then reconstructs details, reversing the traditional encoding and decoding process. This study sheds light on phenomena like eyewitness testimony and stereotyping.
A University of Queensland team has made a breakthrough in understanding the vestibular system, which controls balance and movement. Using optical tweezers, they were able to activate the vestibular system without the animal moving, allowing for the study of neural circuits in the brain that mediate vestibular perception.
Scientists discovered a network of neurons in bees' brains that integrates direction and distance changes, enabling them to return home. A detailed computer model was developed based on this research, which could lead to new algorithms for autonomous robots.
Researchers at the University of Nebraska-Lincoln have identified a Zika virus mutation that contains a sugar in its protein envelope, which may help the virus enter the brain. This discovery could explain why the virus became more lethal during outbreaks in the Caribbean and South America.
Boston University School of Medicine researcher Hugo J. Aparicio is studying the associations between novel vascular biomarkers and cognitive dysfunction in a community-based study. The goal is to identify potential biomarkers for aging-related dementia, which could lead to earlier detection and treatment.
Researchers will investigate how individual differences in stress response affect escalation of alcohol drinking after traumatic stress, with potential treatments for vulnerable populations. The study aims to identify neurobiological targets for treating alcohol abuse in PTSD patients.
A study by NC State University researchers reveals that brain natriuretic peptide (BNP), a neurotransmitter involved in itching sensations, plays no role in pain transmission. This finding could lead to the development of specific drugs or therapies to block pain signals closer to their source.
The NeuBtracker microscope allows for the simultaneous observation of neuronal activity and behavioral responses in zebrafish. This enables researchers to test the effects of substances on both brain activity and behavior, opening up new avenues for drug discovery and metabolic research.
Researchers found that bilingual brains rely more on native language processes when learning a new language, but learn it faster. This study supports the hypothesis that early bilingualism is beneficial for language learners in later life.
The University of Minnesota Medical School's Center for Magnetic Resonance Research has been awarded a $3.5 million NIH grant to develop new, efficient, and safe stimulation paradigms for Deep Brain Stimulation (DBS). The project aims to improve treatment quality for patients with disabling neurological symptoms by increasing the preci...
A study by University of Maryland School Medicine researchers found that elevated kynurenine levels disrupt sleep, leading to cognitive impairments in schizophrenia. The discovery could lead to new treatments targeting kynurenine's role in the disease.
A team of scientists at Beth Israel Deaconess Medical Center has identified a specific subset of neurons that respond to sodium deficiency, triggering an appetite for sodium. The researchers mapped the brain circuitry underlying this behavior and found that it is tightly regulated by hormones such as aldosterone and angiotensin II.
A computational study models the strength of basal ganglia connections between healthy and Parkinsonian brains, revealing a broad overlap in neural connection strengths. The research could lead to customized therapies specific to individual patterns of neural degeneration.
Researchers have identified a novel compound called HT-0411 that enhances long-term memory in animals, leveraging CREB activation and monoamine oxidase B inhibition. The study suggests potential for pharmaceutical enhancements of human memory.
Research found disconnections in brain areas involved in attention and visual processing may contribute to visual hallucinations in individuals with Parkinson's disease. The study used fMRI to examine connectivity between brain areas, showing decreased synchronization in patients with visual hallucinations.
Researchers have discovered a possible biomarker, CCL11, that may allow CTE to be diagnosed in living individuals. The study found elevated CCL11 levels in the brains of former football players with CTE compared to non-athletes and those with Alzheimer's disease. This discovery could lead to targeted treatments for CTE sufferers.
A new study suggests that enhancing breathing via the brain may limit respiratory muscle dysfunction in Duchenne muscular dystrophy patients. Researchers found that the brain compensates for respiratory muscle weakness by increasing diaphragm activation in mice with dystrophin deficiency.
A recent study suggests that large brain size is an adaptation for handling frequent environmental change, allowing birds to colonize seasonal habitats. Contrary to the cognitive buffer hypothesis, the study found no evidence that big brains evolved exclusively in variable environments.