Articles tagged with Brain
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A study combining clinical assessment, genomic analysis, and electroencephalography identified specific gene combinations in autistic patients that distinguished them from those with intellectual disabilities. This integrated approach provides new prospects for diagnosis and understanding of autism's physiological mechanisms.
Researchers found that musicians' brains can incorporate abstract music notation to enhance their visual perception of congruent musical notes. Non-musicians showed no significant difference in visual preference regardless of the melody played.
Research suggests that maternal stress during pregnancy can impact offspring gut and brain development by altering the vaginal microbiome. This study found disruptions in both maternal and offspring gut microbiota composition, leading to metabolic reprogramming of the gut and brain.
Researchers discovered unique white matter injury patterns in patients with concussion-related depression and anxiety, suggesting similar mechanisms to non-trauma dependent depression. Anxiety patients showed diminished fractional anisotropy in the brain's fear modulation region, indicating different treatment targets may be required.
A new study by Indiana University researchers finds that the Aging Brain Care Medical Home program reduces depressive symptoms in two-thirds of patients and caregiver stress by 50%.
A study of 1403 women found that those exposed to higher levels of air pollution had reduced white matter in their brains. Ambient particulate air pollutants may have a deleterious effect on brain aging, according to researchers.
Researchers used CT scans to study the brain anatomy of ichthyosaurs, revealing an enlarged olfactory region suggesting a key role for smell. The findings also show that vision was crucial for these marine predators.
A study by University of Michigan researcher Monica Dus found a hormone that triggers digestive response to real sugar but not artificial sweeteners in fruit flies, suggesting humans may have similar mechanism. This discovery helps explain why diet foods fail to satiate hunger and lead to weight gain.
Researchers studied hawkmoth's ability to hover and track flowers in mid-air while adjusting to changing light conditions. The moths can slow their brains to improve vision under low-light conditions, but only if the flower is moving rapidly.
A new imaging technique uses discrete wavelength decomposition to analyze functional connectivity in the brain, identifying changes in neural communication following mTBI. The study found alterations in connectivity in both acute and chronic stages of injury, with recovery of connectivity over time.
Women experiencing more menopausal hot flashes, particularly at night, are more likely to have brain changes that increase their risk of cerebrovascular diseases such as stroke. This study found a correlation between the frequency and severity of hot flashes and white matter hyperintensities on brain scans.
Researchers found that GLP-1 receptor activation decreases anticipatory food reward, reducing cravings, and increases feeling of food reward during consumption, reducing overeating. The study suggests a potential therapeutic target for substance abuse disorders, offering new insights into the mechanisms of obesity.
Researchers at Salk Institute found that a low glycemic index diet reduced symptoms of autism in mice, including impaired social interactions and repetitive behaviors. The diet may influence gut bacteria and inflammation, which are linked to the development of autism.
Researchers found that personality traits, particularly Neuroticism, affect brain activity in response to eye contact. Participants who scored low on Neuroticism exhibited approach-associated brain activity when looking at someone making eye contact, while those with high scores showed avoidance-associated patterns.
A new study by Johns Hopkins Medicine researchers found that developing delirium in the ICU increases hospital stays and risk of dying, with risks doubled for brain dysfunction. The study also suggests potential causes of delirium include medication use and inflammation outside the brain.
Researchers found that female mice are unable to detect male pheromones until they enter the ovulation cycle, where hormones such as progesterone decrease and allow them to sense potential partners. This study highlights the nose's role in making important decisions about behavior influenced by hormonal signals.
Researchers at TSRI discovered that a hormone called progesterone blocks signals from male odor molecules in female mouse noses during diestrus, leading to 'male odor blindness' and altered behavior. This finding suggests new avenues for studying senses and behavior.
Dr. Laurel H. Carney has been awarded the William and Christine Hartmann Prize in Auditory Neuroscience for her research on auditory physiology and perception. Her work aims to understand how the brain hears and develop strategies to aid listeners with hearing loss.
A Johns Hopkins University-led team discovered that people's brains tend to store colors as one of just a few basic hues, rather than specific shades. This bias affects memory accuracy, making it difficult for individuals to recall the exact color of an object.
Researchers at Binghamton University used brain signals to identify individuals with 94% accuracy, suggesting a new type of biometric security. Brainprints are cancellable and cannot be stolen, offering an alternative to traditional methods.
A new study reveals that social and sensory overstimulation is the primary driver of autistic behaviors, contradicting decades-old views of autism as a mental retardation. The research proposes that autistic brains are hyper-functional, requiring predictable and structured environments to function optimally.
A large study has found that whole brain radiation therapy (WBRT) significantly worsens cognitive function compared to radiosurgery, and should no longer be used in the adjuvant setting after radiosurgery. WBRT's side effects include hair loss, fatigue, and significant interruptions in systemic therapy.
ONT-380 demonstrates activity in stage IV HER2+ breast cancer patients, with one patient experiencing complete regression of brain metastases and improved overall survival. The drug's ability to target the HER2 growth factor receptor makes it a potential treatment for brain metastases.
Research reviews suggest that individuals with cognitive impairment, including dementia and Alzheimer's disease, exhibit altered pain processing. This is often accompanied by increased sensitivity to painful stimuli, making effective diagnosis and treatment challenging due to communication difficulties.
Studies reveal differences in statistical regularities between dark and bright components of the natural world, with implications for understanding cortical networks and perceptual asymmetries. The findings suggest that the brain exploits these patterns to better navigate its surroundings.
A phase I/II clinical trial found that brigatinib responded to treatment in 58 of 78 ALK+ patients, with a 13.4-month progression-free survival rate for those previously treated with crizotinib. Brigatinib also showed promise in treating brain metastases, with a 30% decrease in tumor size and controlled disease for 15.6 months.
A new research team at RI-MUHC has developed a glutamate biosensor platform using revolutionary protein engineering technology Cyto-iGluSnFR. This platform allows for the detection of glutamate levels in brain cells, enabling the screening of millions of chemical compounds to develop new drugs targeting EAATs.
Researchers discovered that synapses facilitate the spread of Tau aggregates in Alzheimer's patients, which could counteract synaptic repair efforts. This new understanding has significant implications for developing therapeutic strategies against Alzheimer's disease.
Researchers used a 3D simulator to test how individuals with Autism Spectrum Disorder process sensory stimuli. Contrary to previous theories, the study found that autistic participants demonstrated intact multi-sensory integration in both coherent and noisy environments.
Researchers from the University of Sydney have found a humane way to kill cane toads by placing them in a refrigerator for a few hours before transferring them to a freezer. This method induces unconsciousness without causing pain, solving a long-standing dilemma for communities affected by the invasive species.
Researchers at Cedars-Sinai Medical Center have developed a tiny drug-delivery system that can identify cancer cell types in the brain through MRI virtual biopsies and then attack the molecular structure of the disease. The nanodrug can distinguish and fight tumor cells in the brain without surgery.
A new study published in Nature Genetics highlights the critical role of essential fatty acids like omega-3 in human brain growth and development. The research, conducted in a rural community in Pakistan, identified a genetic mutation that impairs the brain's ability to absorb these vital fats.
Researchers developed a new method to analyze brainstorms in premature babies, which correlates with their cognitive development at age two. The study uses mathematical functions and software component to analyze EEG signals, providing objective data on brain function in very premature babies.
Research at Duke-NUS Medical School reveals lysophosphatidylcholines (LPCs) are crucial for human brain development and function. Studies show that mutations in the protein Mfsd2a, which transports LPCs, lead to impaired brain growth and function.
A study by the University of Veterinary Medicine -- Vienna found that larger brain size confers a survival advantage to female guppies, but not males. The research, which released large- and small-brained guppies into semi-natural streams, revealed that large-brained fish are better at evading predators, leading to higher survival rates.
A nationwide Danish register study tracking 190,000 individuals found a clear correlation between hospitalization due to infections and impaired cognitive ability. The study shows that even after treatment, patients can experience lasting effects on their IQ scores.
A recent study published by Rice University researchers found that individuals generally prefer to locate their sense of self in the brain. This preference is stronger among those with an independent self-construal, who tend to assert autonomous goals and behaviors related to the brain. In contrast, people with an interdependent self-c...
Patients with liver cancer can be cured with a liver transplant using organs from donors who died of cardiac death, according to the largest study of its kind. The study found no difference in liver cancer recurrence between livers donated after cardiac death and those obtained from brain-dead donors.
Researchers found that brain areas normally dedicated to hearing can adapt to early-stage hearing loss, affecting cognitive decline and speech perception. The study suggests that this compensatory adaptation may lead to decreased brain resources for processing sound.
Researchers at Michigan State University found that children who stutter have difficulty perceiving a beat in music-like rhythms, which may account for their halting speech patterns. This study has implications for treating stuttering and suggests that improving beat perception in children could lead to improved fluency in speech.
A new blood test measures brain-specific proteins released after a traumatic brain injury (TBI) to predict both imaging evidence and injury severity. The test, which uses glial fibrillary acidic protein breakdown products (GFAP-BDP), shows a net benefit in reducing unnecessary CT scans by 12-30%.
Researchers successfully reactivated plasticity in adult brains by transplanting GABA neurons, allowing for vigorous rewiring and improved vision in amblyopic mice. The findings hold promise for future clinical applications and therapies for incurable brain disorders.
Research shows that imagining a visual target before searching for it is faster and more efficient than actual practice. This study suggests that the human brain benefits from visualization, which changes how information is processed early on in the visual system.
Researchers at the University of Cincinnati found that leptin action is normal in obese individuals, not impaired as previously thought. The study suggests that restoring leptin action may not be effective in reducing obesity, requiring a new approach to understanding and treating the condition.
Researchers discovered that an antiviral compound called interferon-lambda can tighten the blood-brain barrier, making it harder for viruses like West Nile to invade the brain. This finding holds promise for treating deadly neurological conditions caused by viral infections.
The Brain and Behavior Research Foundation has awarded $3.9 million in NARSAD grants to 40 independent investigators from around the world. These grants support basic research, new technologies, and next-generation therapies for schizophrenia, major affective disorders, and other serious mental illnesses.
The Edmond and Lily Safra Philanthropic Foundation has donated $30 million to the Hebrew University's Edmond and Lily Safra Center for Brain Sciences, bringing the total funding to $50 million. The center will continue to grow and recruit top researchers to advance brain research and development.
Researchers discovered that fruit flies use a brain structure called the ellipsoid body to navigate and maintain their bearings. The ellipsoid body cells locked onto visual patterns, allowing the fly to track its orientation in the dark.
A study published in Cell reveals the 3D structure of tubulin tyrosine ligase-7 (TTLL7) bound to microtubules, providing insights into how chemical markers influence cell functions. The findings also shed light on how disruptions in these patterns can lead to neurodegenerative disorders.
Researchers used nuclear magnetic resonance spectroscopy and small-angle X-ray scattering to study the effects of high pressure and urea on protein unfolding. They found that while both methods cause proteins to unfold, they do so through different mechanisms, leading to distinct intermediate proteins.
A new non-invasive PET scan with C-11-vorozole detects aromatase in all body organs, potentially identifying cancer patients who may benefit from aromatase inhibitor treatment. The study also finds sex-dependent differences in radiation exposure and hormonal status.
Two proteins, Contactin-4 and amyloid precursor protein, bind during embryonic development to stabilize brain cells involved in image stabilization. This finding suggests precise neural connections are crucial for accurate sensory perception and behavior.
Researchers at the University of Virginia will use single-cell genome sequencing to examine brain samples from people with and without schizophrenia. By comparing these samples, they hope to identify genetic causes of the disease and develop more effective treatments.
A new study suggests that dopamine contributes to chronic pain states by targeting A11 neurons. Removing these neurons can selectively diminish chronic pain in mice. The findings offer potential clues for developing new treatments for chronic pain.
Research led by the University of Pittsburgh Graduate School of Public Health shows that people with type 1 diabetes experience accelerated brain aging, correlated with slower information processing and cognitive difficulties. The study suggests clinicians should screen middle-aged patients for cognitive complications to prevent potent...
A study published in Brain Imaging and Behavior found that brain activity responding to high-calorie food images is lower at night compared to daytime. Researchers used MRI to measure neural responses to food images during morning and evening sessions, revealing a dip in reward-related brain reactivity in the evening.
Research found that prolonged noise exposure alters cells connected to the brain in mice, enabling them to conserve neurotransmitters and better cope with loud conditions. The cells also changed their structure to increase storage capacity for these chemicals.
Researchers at UNC Chapel Hill use exosomes to deliver catalase, a potent antioxidant that counters neuron-killing inflammation, to the brain. This delivery method bypasses the blood-brain barrier and avoids immune detection.
Two Yale researchers received the Bernard Sanberg Memorial Award for Brain Repair, Dr. John Elsworth for his work on cell-based therapies and Dr. Cesar Borlongan for his groundbreaking stem cell therapy research. Their awards recognize significant contributions to neural therapy and brain repair.
A team of researchers at the University of Pittsburgh School of Medicine has uncovered a previously unknown pathway that fine-tunes neural signaling by modulating glutamate NMDA-type receptors. This discovery could lead to new research avenues in understanding neurodegenerative diseases.