Articles tagged with Brain
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers have discovered how light disrupts biological clocks and propose a two-day recovery time for jet lag. They found that weakening synchronization among neurons governed by circadian patterns enables rapid adaptation to new time zones.
Researchers have found that the receptor TLR4 and protein galectin-3 are crucial in amplifying brain inflammation. Galectin-3 is secreted by microglial cells and binds to TLR4, intensifying the inflammatory response.
Researchers at IUPUI are conducting a study on how alcohol affects the brain's reward system, using a unique blend of mathematical modeling and experimental neuroscience. The goal is to gain a better understanding of how alcohol hijacks dopamine release, a key factor in addiction.
A new study reveals that prenatal exposure to low doses of polychlorinated biphenyls (PCBs) can alter the developing brain in an area involved in metabolism. The effects are apparent even two generations later, with increased body weight observed only in descendants of females exposed to PCBs during pregnancy.
Researchers challenge current theories of ageing by finding that brain activity in older adults is not reduced as previously thought. A new study using resting state fMRI measurements suggests that age-related differences in brain signal amplitude are due to vascular health, rather than brain function.
Researchers found altered opioid neurotransmission in obese individuals, with reduced opioid receptors in the brain. The study provides new insights into the mechanisms of overeating and obesity, but its findings do not indicate whether the changes are a cause or consequence of obesity.
The brain uses the sharper image from the less aberrated eye as a reference point to compensate for optical differences between the eyes. This neural mechanism is important for understanding refractive errors and developing effective treatments like monovision for presbyopia.
Researchers at Northwestern University have discovered how a fruit fly's brain represents temperature, mapping it neuron by neuron. The study reveals three types of neurons that respond to hot, cold, or both temperatures, converging in the brain to create a cohesive response.
Researchers found that deleting TREM2 receptor in mice with AD-like disease reduced plaque formation, brain inflammation, and improved neuron survival. Macrophages lacking TREM2 were more effective at clearing beta-amyloid aggregates, suggesting a potential role for the receptor in neurodegeneration.
A teenager returned from a discotheque with classic stroke symptoms was actually diagnosed with Lyme disease due to elevated white blood cell counts in spinal fluid. The patient improved immediately after antibacterial and antiviral treatment began.
A deficiency in GLUT1 protein worsens Alzheimer's disease symptoms by breaking down blood-brain barrier, while targeting this protein may help prevent the disease progression among those at risk. Researchers found that GLUT1 deficiency led to neuronal dysfunction and behavioral changes.
Researchers found that beliefs about nicotine can modulate brain activity and influence behavior, potentially leading to new addiction treatments. The study suggests that belief systems can induce physiological changes, allowing for the reverse-engineering of addiction.
Researchers found that the Gomafu gene is dynamically regulated in the adult brain, affecting behavior related to anxiety and schizophrenia. The discovery sheds light on the gene's potential as a surveillance system for rapid brain responses to environmental changes.
A study published in Science Translational Medicine shows that treating cats with Niemann Pick Type C with cyclodextrin significantly improved their neurological symptoms. The treatment halted disease progression and allowed the cats to live past three years of age, making it a promising potential therapy for human patients.
Researchers evaluated four football helmet add-ons, including Guardian Cap and Concussion Reduction Technology, which showed limited impact on reducing concussion risk. The study found that helmets with these add-ons reduced linear accelerations by about 11 percent but had little effect on angular accelerations.
Research suggests that anesthetics could have a lasting effect on children's cognitive abilities, with those under three years old at higher risk of adverse effects. The University of Toronto team recommends avoiding anesthetics for young children unless necessary for life-saving procedures.
Researchers found that humans can flexibly combine and repurpose pre-existing computations to address new challenges, including online dating and social media. This adaptation allows for rapid deployment of neural resources in new contexts.
A study suggests that Republicans and Independents are more likely to disapprove of lenient neurolaw reforms, while Democrats support equally across framing conditions. This finding underscores the need for careful public presentation of neuroscience in law to maintain a non-polarizing stance.
A seven-year study found that responsive direct cortical stimulation significantly reduced seizures by up to 60% and improved quality of life. The Long-Term Treatment Study showed that 84% of participants experienced some improvement, with 16% being seizure-free for at least three months.
Researchers at Columbia University find that brain neurons apply Wald's sequential probability ratio test to make simple decisions, just like Alan Turing did with the Enigma code. This neural implementation of the test allows for rapid weighing of probabilities and rational decision-making.
Researchers at Northwestern University have found a secret bodyguard for the ears - a newly discovered connection from the cochlea to the brain that warns of intense incoming noise. This novel pain system protects the ear from very loud or damaging noise, which may be why people jam their fingers in their ears when exposed to loud soun...
Researchers at Yale University found that marijuana activates neurons in the brain that normally suppress appetite, leading to increased hunger. The study provides insights into why people often experience extreme hunger after using cannabis.
Research suggests that motorized cycling can prime the brain for relearning everyday tasks and improve motor function in stroke patients. In a small study, 17 stroke survivors showed a 34% improvement in motor skills after exercising on a motorized stationary bike compared to voluntary cycling or no aerobic exercise training.
A six-year clinical trial found that patients with low blood flow to the back of the brain are at a higher risk of recurrent stroke. The study used specialized software to visualize and quantify blood flow, identifying a quarter of patients with low posterior blood flow.
Researchers discovered that brain's grid cells are anchored to one wall and rotated by a specific angle (7.5 degrees) to minimize symmetry and errors in navigation. The rotation is necessary to ensure accurate mapping of environments, even when landmarks are far apart.
Arturo Hernandez, a University of Houston developmental psychology professor, has received the Friedrich Wilhelm Bessel Research Award for his groundbreaking work on how the brain processes language. His research has significant implications for teaching and learning multiple languages, including second languages.
A new study presents a non-invasive test using optic nerve ultrasound to measure sheath thickness, which can help identify acute stroke patients at high risk of dying within days or months. The findings suggest that larger nerve sheath measurements are associated with increased death risk and disability six months later.
A Florida State University and Russian Academy of Sciences team found that space travel may impair the body's ability to regulate blood flow to the brain, contributing to temporary or permanent vision problems experienced by astronauts. The research team plans to conduct further experiments to find solutions.
A recent study published in the New England Journal of Medicine shows that endovascular treatment can dramatically improve patient outcomes after an acute ischemic stroke, increasing positive outcomes from 30% to 55%. The treatment resulted in a 50% reduction in deaths and restored blood flow to the brain.
A landmark study published in the New England Journal of Medicine shows a dramatic improvement in restoring blood flow to the brain after adding stent thrombectomy to standard clot-dissolving therapy. The new treatment restores blood flow to 89% of patients, with 71% returning to independent living.
Researchers discovered that the nucleus prepositus plays a crucial role in generating head direction signals, in addition to its function in eye movements. The study's findings have significant implications for understanding our sense of spatial orientation.
A study found that increasing klotho levels can protect against learning and memory deficits in a mouse model of Alzheimer's disease, counteracting the effects of Alzheimer-related toxins. Klotho's benefits may be due to its effect on neurotransmitter receptors involved in learning and memory.
A study published in The BMJ found that children who drowned and suffered cardiac arrest with hypothermia have poor outcomes if resuscitation continues for more than 30 minutes. Most children (89%) died, while only 11% survived with severe neurological damage.
Researchers at Karolinska Institutet found that eltoprazine significantly reduced Parkinson's disease patients' dyskinesia while maintaining anti-Parkinsonian effects. The treatment was well-tolerated and shows promise as a new therapeutic principle for treating L-dopa-induced dyskinesia.
A team of researchers from Northwestern University and Carnegie Mellon University has made a groundbreaking discovery that could lead to the development of flat-screen displays featuring active touch-back technology. By understanding how the brain interprets data from fingers, the team can design haptic technologies that produce certai...
Researchers found that associating foreign-language terms with gestures and images enhances learning outcomes, outperforming methods relying on listening or reading alone. The brain's motor system plays a crucial role in this process.
A team of chemists at IRB Barcelona has developed a shuttle that can cross the blood-brain barrier and transport various substances into the brain, opening up new possibilities for treating diseases such as glioblastoma and Friedreich's Ataxia.
A study published in Current Biology establishes a molecular-level link between a slow-down in the biological clock and genetic deficits in Angelman syndrome. Experimental treatments targeting the paternal copy of UBE3A gene show promise for treating sleep disorders and other symptoms.
Researchers found diverse genomic changes in single neurons from Alzheimer's patients, showing that over 90% of sporadic Alzheimer's disease brains display highly significant DNA increases. Neurons from patients with sporadic Alzheimer's disease were four times as likely to contain more than two copies of the Alzheimer's-linked gene APP.
A new method has been developed to deliver promising treatments to stroke patients quickly, thanks to the work of paramedics. By working with paramedics in the field, intravenous medications can be given to patients within the 'golden hour,' the window in which brain damage is minimized.
Researchers at Max Planck Florida Institute for Neuroscience and Frankfurt Institute for Advanced Studies report substantial postnatal changes in the functional properties of brain circuits. These changes improve the ability of brain cells to encode information, enhancing brain function.
A study by the University of Colorado Boulder reveals that cocaine's addictive potential is linked to a second brain mechanism involving glial cells and Toll Like Receptor 4. Blocking this mechanism could lead to a new drug treatment for cocaine addiction.
A new study reveals that individuals with TBI struggle with gist reasoning, a complex cognitive capacity. The Center for BrainHealth's assessment tool shows promise in predicting daily life functionality and estimating brain health.
A new study found that HIV penetrates the blood-brain barrier by relying on proteins expressed by mature monocytes. These proteins could serve as a target for preventing HIV from reaching brain cells. The research aims to shed light on novel mechanisms for improving drug delivery to the brain.
Researchers at Vanderbilt University have discovered a new reset button for the brain's master biological clock, which can be stimulated using light to alter sleep patterns. This finding has the potential to lead to new treatments for conditions like seasonal affective disorder and reduce adverse health effects of night shifts.
A new study found that older adults with musical training were 20% faster at identifying speech sounds than non-musicians. The research suggests that music instruction can enhance brain areas supporting speech recognition, even in old age. Music training may help counteract cognitive decline and improve auditory processing abilities.
A new study by University of Cambridge researchers identified a critical threshold in alpha-synuclein protein levels that increases the chances of aggregation and neurodegeneration. The findings provide a mechanistic description of the initial molecular events leading to Parkinson's disease.
Researchers at LSU Health New Orleans have discovered Neuroprotectin D1, a molecule that protects cells from damage and promotes recovery from stroke. This breakthrough could lead to therapeutic solutions for age-related macular degeneration and ischemic stroke.
Neuroscientists studied animats with complex neural networks that evolved to master video games of varying difficulty. The research found that in more complex environments, the animats developed intricate neural connections and increased their ability to integrate information, supporting the theory of Integrated Information Theory (IIT).
Researchers at the Centre for Addiction and Mental Health found a significant elevation of brain inflammation in people with clinical depression. Brain scans revealed increased activation of immune cells, which play a key role in the brain's inflammatory response.
A new LA BioMed study found that platelet transfusions and DDAVP are not effective in preventing further bleeding or death in patients with traumatic brain injuries. The researchers analyzed data from 408 patients and found no significant differences in mortality or hemorrhage progression between those who received the treatments and t...
A study published in the Journal of Clinical Investigation found that a genetic polymorphism may be responsible for why standard treatments for hypothyroidism fail some patients. The researchers suggest that personalized medicine could lead to effective treatment for all patients, and identify potential targets for new therapies.
Researchers found that inhibiting the activity of a signaling protein called MEKK3 could prevent CCM-related heart defects and potentially treat the disorder. The study also identified a previously unknown signaling pathway involved in CCMs.
Researchers discovered that an anti-inflammatory protein can increase plaque formation in the brain by binding to amyloid-beta and accelerating its buildup. The study suggests that Alzheimer's treatment should be tailored to patients carrying specific APOE variants, such as APOE4, which is a major genetic risk factor for the disease.
Research explores how gut bacteria influence brain activity, sleep, stress responses, and disease development. The human microbiome's role in brain function is a growing area of study, with potential therapeutic applications through dietary modification.
Researchers have made breakthrough discoveries in understanding Pelizaeus Merzbacher disease (PMD), a devastating neurological condition. The study found that myelin-producing cells are still active and can be stimulated to produce more myelin, potentially leading to new treatments for PMD and multiple sclerosis patients.
A new study found that individuals with autism spectrum disorder tend to display uniquely individualistic brain organization patterns. The researchers suggest that these idiosyncrasies may be a result of disrupted interactions with the environment.
The 'Open MIND' collection features 39 original articles and commentaries from leading researchers, covering topics like conscious thought processes, perception, and ethics. The project showcases a novel approach to publishing, with peer-reviewed quality control and fast production times.
New research reveals that individuals with autism display 'idiosyncratic' brain synchronization patterns, which are distinct from those of typically developing individuals. This finding has significant implications for early diagnosis and future treatments of the disorder.
A study published in Current Biology found a causal link between serotonin neuron activation and patient behavior in mice, contradicting the notion that increased serotonin leads to reward. Researchers used optogenetics to activate serotonin neurons, observing longer waiting durations in mice with stronger activation.