Scientists at Tsinghua University and Beihang University developed a 'microtube pump' that can transport tiny amounts of fluid using sunlight-powered capillary forces. The pump consists of two layers with asymmetric properties that work together to accelerate water droplets to exceptional speeds.
A new transgenic rat model accumulates amyloid specifically in brain blood vessels, strongly mimicking human cerebral amyloid angiopathy. The rTg-DI rats exhibit progressive accumulation of brain blood vessel amyloid-associated inflammation, cognitive impairments, and microbleeds.
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Researchers at the University of Helsinki have identified a monoclonal antibody that inhibits capillary leakage in sepsis. The antibody targets β1-integrin, a key molecule in endothelial cells, and improves junctions between endothelial cells, decreasing vascular leakage and protecting against sepsis-induced heart failure.
Prellis Biologics has developed record speed and resolution technology for printing human tissue with viable capillaries, a major hurdle in organ engineering. This breakthrough enables the production of thick, functioning tissue for drug testing and ultimately human organs.
Researchers have discovered that gas embolotherapy, using acoustic droplet vaporization, can starve tumors by shutting off blood flow and also deliver drugs through the capillaries
Researchers developed a new computer model predicting blood flow through capillaries, finding that vessels can switch between even and uneven flow. This study has significant implications for understanding healthy and disease states, and may lead to better prediction of drug transport in microvascular networks.
Researchers found that restoring SIRT1 reverses vascular aging, increasing capillaries and endurance by up to 80%. The study shows promise for preventing age-related diseases like cardiovascular disease and frailty.
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A team of researchers used a state-of-the-art simulation code to study the behavior of red blood cells flowing through physiologically realistic microvascular networks. They observed that red blood cells frequently jam for brief periods before proceeding downstream, causing temporary increases in vascular resistance. The findings have ...
Pericytes, a type of cell on brain blood vessels, grow to cover empty space left by neighboring cells. This brain plasticity may help fight age-related vascular disorders like Alzheimer's disease and stroke.
Researchers at ITMO University developed a system to measure red blood cell velocity using high-speed video recording. The system provides accurate data for diagnosing vascular conditions and assessing therapy efficiency, offering a reliable tool for disease pattern recognition.
Researchers found that a synthetic peptide called TIP strengthens the barrier function of lung capillaries, preventing fluid accumulation and potential deadly complications. The study suggests a promising strategy for reducing dangerous fluid volume in lungs, particularly for vulnerable populations like children under five.
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A new micropropulsion system for CubeSats uses an innovative design of tiny nozzles that release precise bursts of water vapor to maneuver the spacecraft. The FEMTA thruster technology demonstrates a thrust-to-power ratio of 230 micronewtons per watt, making it a viable method for attitude control of CubeSats.
Researchers at the University of Warsaw have developed a method to form colloidal chains by pulling out individual particles from a suspension using an electrode. The chains are held together by a thin layer of liquid, and their flexibility is influenced by the type of liquid used.
Researchers used a lattice-Botzmann method to simulate the impact of microdroplets on dry surfaces, revealing distinct physics at the microscopic level. They found that droplet sizes in spray cooling are three orders of magnitude smaller than previously studied millimeter-size droplets, and that this affects their dynamics.
Researchers have developed cotton candy-like fiber networks that dissolve in water below 32 degrees Celsius, enabling the creation of self-destructing circuit boards. These devices have potential applications in military and health fields, including implanted medical devices that can disintegrate with ice application.
A new study by Huazhong University of Science and Technology finds that maximizing energy density within the capillary chamber yields the longest plasma jet. Varying capillary dimensions, cathode diameter, and cathode tip length are key factors in achieving optimal performance.
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Researchers developed two new tools to diagnose systemic sclerosis earlier: nailfold videocapillaroscopy and a blood test detecting SSc-specific autoantibodies. These tools show promise in identifying patients with the characteristic appearance of early SSc patterns, aiding targeted treatment before irreversible damage occurs.
Researchers at North Carolina State University have developed a new technique for 3D printing using a paste of silicone particles in water. The method uses capillary attraction to link together tiny beads, creating porous and flexible structures.
Researchers have discovered the mechanism behind granular capillarity, where sand rises in a tube under vertical vibrations. The study found that convective motion of sand grains causes an upward pressure on the base of the column, leading to its ascent.
Researchers identified six people with hypertriglyceridemia whose bodies produce autoantibodies against GPIHBP1, preventing LPL from reaching capillaries. This newly discovered syndrome, dubbed the GPIHBP1 autoantibody syndrome, has life-threatening potential and may be treatable with immunosuppressive drugs.
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Capillaries in the brain's wire-like network can sense activity and generate signals to direct blood flow and deliver nutrients to neurons. This mechanism enables precise control over cerebrovascular blood flow to meet the brain's changing energy needs.
Researchers have developed a new model that better calculates the expected level of capillary rise in nano-channels, which is crucial for fracking. The model takes into account the surface roughness of the capillaries and adjusts parameters to account for frictional drag.
Biomedical engineers at North Carolina State University have created affordable paper pumps using capillary action that power portable microfluidic devices. These devices hold promise for use in applications ranging from diagnostics to drug testing, offering advantages such as portability, low cost, and disposability.
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Scientists have developed a new technique to examine blood vessels in the brain using 3D Image Analysis, allowing for greater understanding of how diseases like dementia, brain cancer, and stroke affect veins and capillaries. This innovative method could help identify early warning signs of these illnesses, potentially saving lives.
Researchers at Medical University of South Carolina discovered that pericytes contribute to capillary damage and blood leakage during ischemia, which can lead to neurological conditions involving ischemia. The study used advanced imaging techniques to track MMP-9 activity and plasma leakage in intact brains of live mice.
Researchers discovered that thorny devils can extract significant quantities of water from soggy sand, but not enough from dew. The lizards' skin is covered with microscopic channels that take up water by capillary action, allowing them to drink without licking water.
Researchers found that capillary forces from soap foam induce pressure gradients near the container walls, reducing sloshing motion. The dampening effect happens faster than expected exponential decay, causing the waves to stop after a finite time.
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Researchers at the University of Manchester have developed a method to create artificial capillaries with atomic-scale precision, opening up new avenues for filtration, desalination, and gas separation. The technology uses graphene as a template to produce ultra-thin cavities with tailored properties.
Researchers discovered that microvessels in the brain play a key role in reacting to spikes in demand and accelerating blood flow to respond to neuronal activity. The findings could help explain cognitive decline in Alzheimer's disease.
Scientists at OIST have developed a new method to fabricate glass microlasers, called whispering gallery microlasers, which are tiny optical devices that create intense light with one color or wavelength. The new technique allows for quick and easy fabrication of smaller devices for biosensing and optical communications.
Researchers found that CTC clusters can unfold and pass through constrictions in microfluidic devices and human blood vessels. This ability may contribute to their metastatic potential. The study suggests potential strategies to reduce clusters' ability to spread cancer throughout the body.
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Researchers found that subtle changes in the air-water interface shape near the surface of capillaries significantly impact drying rates. By controlling microstructure, drying time can be improved. The study's findings could lead to more efficient porous materials for various industries.
Researchers discovered how small capillaries form during angiogenesis, a process crucial for embryonic development, cancer, and diabetes. Blood pressure drives the membrane of endothelial cells to cave in and grow into the cell's body.
Researchers at Washington State University are developing a computer model and designs for improved liquid transport systems using capillary forces to move liquids through narrow spaces in space. By studying the effects of viscosity in microgravity, they aim to conserve energy and enable longer space missions.
A new method to measure supersonic nozzle pressure uses a 'battle of pressures' between hydrogen and helium, enabling precise control in accelerator technology. This breakthrough has significant applications in miniature satellites, lab-on-a-chip devices, and laser plasma accelerators.
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Researchers at ETH Zurich have discovered how dendritic cells advance from capillary vessels towards the lymph node. They found that the cells orient themselves with the help of a molecular mediator named CCL21, which creates a directional gradient.
Researchers at Vanderbilt University have successfully created three-dimensional artificial capillary systems using cotton candy machines, which can keep living cells viable and functional for over a week. This breakthrough technique uses hydrogels as scaffolds to support cells within artificial organs.
The team demonstrated that a laser pulse can accelerate an electron beam and couple it to a second laser plasma accelerator, achieving higher energy. The solution used two different kinds of LPA, including a discharge capillary and a jet of supersonic gas, and developed a disposable mirror system for staging.
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Researchers have invented a technique to dramatically accelerate protein evolution, allowing them to test millions of variants in hours or days. The technology, called µSCALE, enables the identification of promising variants and their DNA sequences, paving the way for breakthroughs in medicine, industry, and biosensors.
A study by Meredith Chivers found that heterosexual women exhibit diverse patterns of sexual response to both male and female stimuli, challenging previous assumptions about heterosexuality. The research suggests a more nuanced understanding of the relationships between sexual identity, attractions and genital responses.
A polymer hydrogel material alters capillary forces, creating a 'stick-slip' control of water entry into microtubes. This enables precise control of fluid flow and could enable applications such as controlled drug release and precise reaction timing.
A recent study published in PNAS shows that young capillary vessels can rejuvenate aged pancreatic islets, suggesting a new way to treat age-dependent dysregulation of blood glucose levels. By replacing the islet vasculature with young capillaries, glucose homeostasis was fully restored.
Researchers at Georgia Institute of Technology have developed a new type of foam called capillary foam that solves many of the problems faced by traditional foams. This new foam is stable for months or years and can be made using a small amount of oil, expanding the range of particles useful for stabilizing foams.
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New research by Penn State scientists suggests that hydraulic fracturing water is not a significant risk to groundwater, as it is sequestered in the rock formation. The study found that capillary and osmotic forces prevent upward migration of residual treatment water into overlying groundwater.
University of Missouri researcher James Lee has been awarded a $1.5 million NIH grant to investigate the link between amyloid-beta peptide and blood capillary damage in Alzheimer's patients. His study seeks to understand how A-beta interacts with cerebral endothelial cells, leading to cell breakdown and neuronal degeneration.
A new 3D capillary device has been developed to improve the manufacture of high-quality liposomes, a crucial step in delivering drugs directly to cancer cells. The device increases production threefold while reducing costs, offering a significant breakthrough for the field.
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Researchers at Indiana University have developed a new technique that can detect microscopic changes in the retina caused by diabetes, which may indicate potential sight-threatening complications. The instrument uses adaptive optics to provide highly magnified retinal images and identify subtle changes in blood vessels.
Researchers at UCL found that pericytes, which control blood flow in capillaries, die around strokes causing lasting brain cell damage. New treatments targeting these cells may help restore normal blood flow and prevent ongoing slow damage after a stroke.
Researchers at the University of Manchester have discovered that graphene can be used to create ultrafast filters for liquid water, with an astonishingly accurate mesh that allows precise separation of atomic species. The filters also exhibit 'ion sponging' properties, sucking up small ions and concentrating them internally.
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A new method developed by the Institute of Physical Chemistry of the Polish Academy of Sciences measures diffusion coefficients and equilibrium constants to assist in determining optimal drug doses. The method uses a simple capillary apparatus with high-speed water flow, allowing for fast and accurate measurements with increased accura...
Scientists have successfully engineered dermo-epidermal skin grafts that contain functional blood and lymphatic capillaries, which can rapidly supply tissue fluid and prevent accumulation. This breakthrough could improve wound healing and organ structure of these skin grafts.
Researchers have verified the classical Landau-Squire theory in a nanoscale fluid jet, measuring flow rates of tens of pico liters per second. The findings suggest that the Navier-Stokes equations hold true at molecular scales, with potential applications in ultra-low-volume injectors and microfluidic logic circuits.
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Researchers found marked bilateral retinal vessel leakage in half of healthy volunteers exposed to high altitudes. The study suggests that retinal capillary leakage may be a key component of high-altitude retinopathy.
Scientists observe unusual orientation behavior of small particles flowing through thin capillaries, which changes direction at narrow points. This discovery has significant implications for technical spinning processes and the understanding of vascular stenosis.
Researchers at the University of Michigan have developed a method to build robust blood vessels using adult stem cells, which may lead to new treatments for circulatory diseases such as diabetes. The technique involves injecting endothelial cells and support cells into a scaffolding carrier, resulting in mature, functional capillaries.
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Researchers have developed a new technology called photoacoustic flowoxigraphy that allows for the measurement of oxygen in individual red blood cells in real-time. This breakthrough could lead to a better understanding of oxygen delivery to normal and diseased tissues, as well as how different disease therapies impact oxygen levels.
EPFL researchers have developed a method to shrink glass capillary tubes using a scanning electron microscope, resulting in precise control over the tube's diameter. This technique has been patented and shows promise for industrial applications such as ultra-high precision printing and surgery.
A novel marker that measures relative changes in the number of capillaries under the skin can accurately predict preeclampsia risk in pregnancy, improving upon existing screening tests. This non-invasive technique identified high-risk women with 87% accuracy and demonstrated significant benefits for timely medical care.
MIT researchers have developed a new method to study droplet adhesion using a modified scanning electron microscope. They found that the angle of a droplet's leading and trailing edges relative to a surface plays a crucial role in determining whether it sticks, and that surface texture on rough surfaces can either improve or worsen adh...
Researchers at Drexel University identified the physical forces in red blood cells and blood vessels underlying the symptoms of sickle cell disease. They found that rigid sickle cells do not get stuck in narrow capillaries, but instead cause partial obstructions in wider vessels.
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