Articles tagged with Capillaries
Scientists create novel hybrid bioprinting technique to replicate human vascular networks, achieving scale and complexity previously unattainable. The breakthrough enables the fabrication of hierarchical vascular networks in one, two, and three dimensions.
Researchers from Uppsala University found that lymphatic endothelial cells have a lobate shape due to their capacity to change shape and increase overlap between cells. This shape supports resilience to changes in fluid volume and is also found in plant leaves.
Persistent microvascular over-dilation may cause muscle hypoxia, worsening chronic limb-threatening ischemia outcomes. Research suggests this phenomenon could be used to screen and treat patients with the disease.
Ken Perry, a UTA senior, has been recognized for his research on the connection between high-fat meals and cardiovascular health. He won two awards from the American Physiological Society for his work analyzing data collected from previous studies, which showed a correlation between high-fat consumption and changes in brain blood flow.
A recent study published in Journal of Neuroinflammation has uncovered a new contributor to the formation of brain hemorrhages, highlighting increased interactions between aged red blood cells and brain capillaries. The research offers potential avenues for innovative approaches to treatment and prevention.
Researchers discovered a non-invasive eye exam that can detect early signs of cognitive decline and cerebral small vessel disease, a major contributor to vascular dementia. The study found connections between altered retinal blood flow and changes in brain structure associated with the condition.
Researchers developed a new imaging technique using Bessel beam two-photon microscopy to detect stalling in brain capillaries, which can indicate acute neurological issues. The approach generates clear images of all capillaries every two seconds, providing better temporal resolution and enabling the detection of short stalling events.
Researchers developed an innovative imaging approach using two-photon microscopy to analyze retinal microcirculation, revealing significant changes in blood flow that may indicate brain diseases. The study suggests that microcirculation in the retina could serve as a promising predictor of cerebrovascular diseases.
Researchers develop a new technique to measure blood attenuation using a fluorophore-coated guidewire, improving the accuracy of near-infrared fluorescence in cardiovascular imaging. The method provides accurate information on vessel walls and outperforms existing correction methods.
Scientists have found that antibodies targeting βII-spectrin on mesangial cells are the trigger for IgA nephropathy. This discovery enables blood-based diagnosis and may lead to improved treatments.
Researchers at Aston University have discovered a new approach to process LDF light signals, allowing for more precise measurement of blood flow in specific areas of the vascular bed. This innovation has shown significant improvement in diagnostic accuracy for detecting microvascular changes in patients with type 2 diabetes and age-spe...
Researchers discovered three essential amino acids - leucine, valine, and tryptophan - as potential metabolic biomarkers for HCC. The study used metabolomics to analyze the differences in tumor and non-tumor tissue metabolomes, revealing striking differences that could aid in diagnosis.
Scientists aim to improve vein health for patients undergoing heart bypass surgery and dialysis. They discovered that two genes play a crucial role in smooth muscle cell differentiation, enabling veins to mature and function like arteries.
Researchers from Tokyo Metropolitan University uncover the rapid growth of ultra-thin nanowires or 'whiskers' in organic compounds by following gas bubbles. They find that adding impurities can suppress bubble formation, allowing for controlled whisker-free growth and uniform crystalline material.
Biomedical engineers at Duke University have created a method to scan and image the blood flow and oxygen levels inside a mouse brain in real-time. The new imaging approach breaks long-standing speed and resolution barriers, enabling researchers to uncover insights into neurovascular diseases like stroke, dementia, and acute brain injury.
Researchers have identified a potential method of preventing damaging seizure activity by restoring the integrity of blood vessels in the brain. This breakthrough could hold promise for treating patients who are currently non-responsive to anti-seizure medications.
Researchers found that brains from patients with Alzheimer's disease had higher levels of the protein Fli-1 and fewer pericytes lining their smallest blood vessels, leading to leakage. Blocking Fli-1 improved memory in mice, suggesting a promising new approach to treating the disease.
Researchers at the University of Leeds discovered that deactivating the Piezo1 protein, a blood flow sensor, reduces muscle capillary density and restricts blood flow to muscles. This results in reduced exercise capability and increased risk of disease, highlighting the crucial link between physical activity and physical performance.
Researchers at CRCHUM have identified damaged nanotubes connecting pericytes as a major contributor to glaucoma. The study reveals that restoring calcium equilibrium within pericytes can recover vascular and neuronal functions, paving the way for new therapeutic approaches.
Researchers from Göttingen University and Hannover Medical School have detected changes in heart muscle tissue of people who died from Covid-19. The study used innovative X-ray imaging to visualize the affected tissue in three dimensions, revealing a network of chaotic vessel formations.
A study published in the American Journal of Respiratory and Critical Care Medicine found that prostacyclin treatment reduced damage to vital organs and halved mortality rates among critically ill Covid-19 patients. The research team hopes to investigate larger patient populations in future studies.
Researchers at TU Wien have successfully described the 'teapot effect' with a theoretical analysis and experiments. The effect occurs when a liquid is poured out of a teapot too slowly, causing it to dribble down the outside of the pot due to an interplay of inertia, viscous, and capillary forces.
A lung model mimicking complex anatomy has enabled the assessment of respiratory volumes using a gas-in-scattering-media absorption spectroscopy (GASMAS) technique. The study demonstrates the feasibility of GASMAS to sense changes in gas volume in a controlled environment, paving the way for potential clinical applications.
Microglia play a vital support role in maintaining blood vessels in the brain, regulating blood flow and capillary diameter. This discovery may lead to new therapies for diseases affecting small brain vessels, such as Alzheimer's and stroke.
Researchers have developed a dye-free method to visualize blood flow in the brain, allowing for detailed mapping of small capillaries and assessing blood flow rates. The technique has potential applications in understanding cardiovascular diseases, tumor growth, and targeted drug delivery.
A team of researchers has uncovered the intricate cellular mechanism behind calcium's role in regulating energy supply to specific brain regions. By studying calcium signals in capillaries, they found that increased calcium levels trigger nitric oxide production, leading to vessel relaxation and enhanced blood flow.
Researchers found significant correlations between brain capillary curvature and neurite thickness radius in schizophrenia patients, but not between capillary diameter and neurite thickness. The study suggests neurovascular abnormalities contribute to schizophrenia.
Researchers at ETH Zurich have discovered that dendritic cells can migrate more quickly to lymph nodes via a newly found pathway during inflammation. This route allows them to bypass the slow and energy-intensive process of entering capillary vessels, enabling faster immune activation and response.
A new study reveals that retinal scans can identify early signs of Alzheimer's disease by detecting changes in blood vessels associated with the APOE4 gene. The research provides a potential path forward for early detection and treatment of neurodegenerative diseases.
Scientists transform circles into squares by temporarily softening a stiff material using capillary force, allowing for durable and reversible topological changes. The new approach enables applications in information encryption, selective particle trapping, and tunable mechanical properties.
Scientists created a mixture of silicone-coated and normal sand to study the behavior of wet granular materials. Adding a certain threshold of magic sand leads to an abrupt change in clustering and rigidity, allowing for the tuning of flow properties.
A study published in JAMA Neurology suggests that large bone marrow cells called megakaryocytes may be responsible for the lingering aftereffects of severe COVID-19 cases, including brain fog. The researchers found evidence of megakaryocytes in the brains of patients who died from COVID-19 and believe they may reduce blood flow to the ...
Researchers used two-photon imaging and optogenetics to isolate brain capillaries in animal models, discovering that pericytes regulate blood flow through a slower process than upstream arteries. The findings have implications for stroke treatment and potential therapeutics.
Researchers at the University of Manchester have clarified the science behind sandcastle building by resolving a century-old mystery. They created artificial capillaries where water vapor can condense under ambient conditions, showing that the 150-year-old Kelvin equation remains surprisingly accurate even at an atomic scale.
A team of KAUST engineers has untangled the roles of water, hydrophobicity, and environmental factors in water electrification. They found that hydrophobic surfaces carry a negative surface charge, which attracts positive ions and repels negative ions from water.
Researchers observed cells moving through small channels to understand cell migration in 3D environments. The findings suggest that cancer cells may penetrate tissues and be blocked within small capillaries, potentially allowing them to metastasize.
A new study from the University of Copenhagen found that postmenopausal women have impaired formation of small blood vessels in their muscles, which can lead to increased risk of cardiovascular disease and type 2 diabetes. Physical activity prior to menopause may help prevent this decline.
A new study published in the Journal of Physiology found that exercising before menopause is crucial for women to develop blood vessels in muscles and improve muscle strength. The research revealed that capillaries in skeletal muscle are essential for physical capacity, health, and insulin sensitivity, which can lead to Type II diabetes.
Scientists at the CRCHUM found that pericytes use tunneling nanotubes to communicate with each other, regulating blood supply and maintaining vision. The study's findings suggest that damaged tunnelling nanotubes may contribute to neurodegenerative diseases like stroke, glaucoma, and Alzheimer's.
Researchers have developed a new technique to create microcapsules that respond to changes in pH, useful for applications like anti-corrosion coatings. The technique uses emulsion templates and allows control over shell thickness, core volume, and capsule size.
Researchers found that water rises up to 9 inches in the capillary fringe, controlling important functions like contaminant breakdown and carbon storage. The team also discovered that microbes behave differently depending on oxygen levels, requiring ideal conditions for decomposition.
Scientists at University of Zurich create custom X-ray contrast agent 'XlinCA' for improved vascular imaging. This breakthrough allows for complete and uninterrupted visualization of blood vessels in humans and animals, reducing the need for animal experiments.
A team of researchers proposed a new theoretical model to describe the balance of capillary forces at the contact line. The model, validated through molecular dynamic simulations, provides new insights into the mechanisms of wetting and capillarity.
Researchers have developed a new method of depositing catalyst particles to tiny electrodes, providing a clean and easy-to-use approach for testing various catalyst materials. This innovative technique allows for the stable and reproducible application of different catalysts on liquid cell TEM chips.
Researchers found that capillary forces in graphene oxide hydrogels can be regulated by surface tension, allowing for the creation of dense yet porous materials. By using solvents with different surface tensions, the microstructure of the resulting materials can be precisely manipulated and densified.
Researchers found that increasing small blood vessels, rather than just improving circulation, could aid recovery from movement difficulties. The study uses a rat model to show that growing more capillaries is a new treatment option for conditions like heart disease and diabetes.
Researchers have identified three proinflammatory mediators driving capillary regression, a common feature of many diseases. The study found that combining drugs to block these mediators can prevent capillary loss and improve outcomes.
Researchers created 3D human capillaries to study how red blood cells navigate ultra-small blood vessels. Malaria-infected cells become stalled due to shape and motion changes, increasing risk of adherence and blockage.
Researchers create carbon nanotube film that generates heat, causing materials to fuse together without the need for huge ovens or autoclaves. The technique produces composites as strong as those made in conventional manufacturing methods, using only 1% of the energy.
Researchers at Kanazawa University developed a method to fill nanopipettes using a temperature gradient, achieving complete filling of a batch with pore diameters below 10 nm. The 'air bubble' that typically remains near the pipette's pore end can be removed by applying the temperature gradient.
Scientists discover molecular coordination tool and specialized lymphatic capillaries that transport immune cells and drain excess fluids from tissues, controlling fluid composition and cell synchronization during hair follicle stem cell activity.
Researchers developed a portable PLOT-cryo device to screen cargo for hazardous materials. The instrument can detect low concentrations of chemicals and requires minimal sniffing time, making it suitable for busy port inspections.
As humans age, their brains receive increased load from the heart's beating due to stiffening large arteries, causing damage to smallest blood vessels. The hippocampus, crucial for episodic memory, is particularly vulnerable to this increased stress.
A study investigates the dynamics of bubble pinch-off in highly confined capillary tubes, revealing two distinct stages of neck contraction with varying dependence on time. The results suggest that the first stage is driven by contact line movement, erasing system memory and leading to universal dynamics.
A KAIST research team visualized pulmonary microcirculation in vivo using a custom-built 3D intravital microscope imaging system. They found that neutrophils aggregate inside capillaries during sepsis-induced acute lung injury, leading to tissue hypoxia and damage.
Researchers at IBS report discovering spontaneous oscillations in microfluidic droplet networks, similar to our blood capillaries. Adding irregularities to the network relieves blood traffic cloggings, suggesting cell collisions or diameter variations help avoid dangerous oscillations.
Researchers detected vascular changes in the human eye using an infrared camera, providing a new potential biomarker for identifying individuals at high risk of progressing to Alzheimer's. The study aims to explore the correlation between retinal capillaries and other brain biomarkers.
A Kanazawa University study reveals that RAGE binds to oxytocin, facilitating its transport through the blood-brain barrier and central nervous system. The findings show that oxytocin plays a crucial role in maternal nurturing behaviors, with reduced survival rates observed in offspring when mothers lack functional RAGE.
Researchers at DESY achieved a world record in plasma acceleration using a laser drill, accelerating electrons to an energy of 7.8 billion electron volts. The technique uses a laser pulse to drill through a plasma, confining the beam and enabling the acceleration of particles hundreds of times stronger than conventional accelerators.
Researchers at City University of Hong Kong create innovative method to transport micro-droplets using capillary force on slippery surface, enabling detection of E. coli and S. aureus bacteria in biomedical analysis. This technology has potential applications in fog collection, water harvesting, heat exchangers, and other fields.