Researchers at Bar-Ilan University have developed a novel method for rapid repair of peripheral nerve injuries using nerve guidance conduits filled with engineered aligned collagen gels and NGF-coated magnetic particles. This technique has shown improved axon growth and functional motor restoration in rats with peripheral nerve injury,...
Scientists from UCLA Jonsson Comprehensive Cancer Center identified TAF12 as critical to the formation of preinitiation complexes, which are necessary for gene transcription. Eliminating TAF12 destroys preinitiation complexes and drastically reduces genome-wide transcription.
Researchers have discovered that increased levels of protein Tumour Protein D54 can increase and decrease the movement of cancer cells, suggesting its potential role in tumour spread. The study found that reducing or increasing this protein's expression affects cell migration, with higher levels leading to more metastasis.
Eija Kononen is a Professor and Chair of Periodontology at the University of Turku, Finland, known for her pioneering work on oral microbiology and its role in immune response. Her novel salivary diagnostic method, the Cumulative Risk Score, has been used in several studies to diagnose periodontal status.
Researchers have identified highly conserved sequences in viral proteins that could make them effective drug targets. The study found two promising sites: one overlapping the RNA binding site of nsp13 and another containing the catalytic site of nsp12, both involved in viral RNA replication and transcription.
Researchers at the University of Waterloo found that people who experience intense boredom frequently in everyday life may seek 'flow' by playing smartphone games to escape their feelings. This 'boredom fix' can lead to negative consequences and excessive gaming, ultimately increasing depression.
A new algorithm has been developed that can guide a quadrotor drone through a series of waypoints on a circuit, beating the fastest lap of two world-class human pilots. The algorithm generates time-optimal trajectories that fully consider the drones' limitations, resulting in faster and more consistent flight times.
A new study from Oregon State University found that infants born within 3 kilometers of oil and natural gas drilling facilities in Texas had slightly lower birthweights than those born before drilling began. After accounting for other potential factors, the study found a significant association between living near an active drilling si...
Researchers from the University of Malta applied genomics to identify genetic variants causing pregnancy-induced diabetes, highlighting the disorder's genetic heterogeneity. The study provides new insights into the aetiology of complex traits and reinforces precision medicine research.
Researchers identified an immune component, STING, linked to Niemann-Pick disease type C, a condition with no effective treatments. The discovery suggests a new therapeutic target for the disease and offers hope for treatment with immune inhibitors.
Researchers at Ural Federal University have created a technology to generate energy for electric car engines using methanol, resulting in high efficiency and minimal emissions. The method uses synthesis gas produced from methanol, which is then fed into an electrochemical generator based on solid oxide fuel cells.
A new decision tree tool has been developed to differentiate the endangered salt marsh harvest mouse from its abundant look-alike, the western harvest mouse. The tool uses machine learning to analyze characteristics such as belly color and tail hair, allowing for accurate identification with high accuracy.
A clinical trial found pimavanserin significantly improves sustained symptom benefit and reduces relapse rate in people with dementia-related psychosis. The treatment also showed fewer serious side effects compared to other antipsychotics.
A new study highlights challenges of achieving equity for diverse patients in communication at hospital discharge. The survey found that one in four patients were alone without a family member or friend, while over half reported limited access to medical interpreters and translated materials.
Researchers provide a systematic overview of printing technologies for scaling up perovskite solar cells, highlighting the key role of ink engineering in achieving high-quality thin films. The study also discusses the technical feasibility of printing additional layers and presents progress on roll-to-roll printing and stability issues.
The COVID-19 pandemic has been shown to affect our sleep patterns, with a higher number of awakenings and difficulty falling asleep reported during lockdown. In contrast, post-lockdown periods saw an increase in dream recall and more lucid dreams, with people also reporting more dreams related to crowded places.
Researchers identified cell diversity in embryonic salivary glands through single-cell transcriptome analyses, revealing early establishment of transcriptional identities. The study provides comprehensive descriptions of molecular signatures defining specific cellular landmarks.
A novel method predicts COVID-19 clinical trial success rates by analyzing features from clinical trial reports, including keywords and drug information. The model achieved high accuracy in predicting trial status, indicating a potential tool for optimizing research efforts and reducing costs.
Alvaro Della Bona, University of Passo Fundo Professor, received the 2021 Wilmer Souder Award for his contributions to dental biomaterials research. He is recognized internationally for his publications and invited presentations on the topic.
Researchers at NYU Tandon School of Engineering developed a framework called DeepReDuce that streamlines neural networks to be more adept at computing on encrypted data. The team found that DeepReDuce improved accuracy and reduced ReLU count by up to 3.5% and 3.5×, respectively.
Research from the University of Illinois found that children eat more fruits and vegetables with longer seated lunch times. The study suggests that policies requiring at least 20 minutes of seated lunch time can help achieve this goal, particularly for children from low-income families who may not have resources to bring their own lunch.
A recent study published in PLOS ONE explores the experience of pure consciousness during meditation, identifying 12 key factors that characterize this state. These findings provide insight into human consciousness and have implications for further research, including potential applications beyond meditation practices.
A large observational study found that two monoclonal antibodies reduced hospitalizations among high-risk patients with COVID-19, regardless of comorbidities. The study showed a low rate of hospitalizations when patients received the treatment early on.
Martin Thornhill, a renowned professor at the University of Sheffield, has received the 2021 IADR Distinguished Scientist Award in Pharmacology/Therapeutics/Toxicology Research. He is recognized for his sustained contributions to dental and medical research, covering topics such as oral mucosa conditions.
Researchers have discovered a link between cognitive decline and faster bone loss in women, increasing future fracture risk. Cognitive decline over five years was associated with a 1.7-fold increase in fracture risk in subsequent 10 years.
Jeffrey Ebersole, Sharon Grayden, and Stephen Bayne received the 2021 AADR Presidential Citation for their significant contributions to the Association. The citation honors individuals who have made lasting impacts on dental research and advancing the mission of the AADR.
Research from Bocconi University reveals that mafia connections harm a company's financial performance, leading to lower return on assets, higher debt, and lower cash holdings. Connected firms are also more likely to go bust, with a 25.5% increase in default risk.
Researchers at the University of California, Irvine have created a new type of camera technology that can visualize various materials and structures with detailed chemical information. The technology uses nonlinear optical effects in silicon to capture depth-resolved images on a camera in one shot, allowing for faster inspection of obj...
Researchers at Carnegie Mellon University have developed a new approach to study neuronal interactions, combining spike count correlation and dimensionality reduction methods. This integration provides a more comprehensive understanding of brain function, shedding light on how neurons communicate and influence various bodily functions.
A study published by The BMJ found that remote 24-hour monitoring for cancer patients receiving chemotherapy significantly reduces symptom burden, anxiety, and work limitations. Patients who used the system experienced improved quality of life and reduced supportive care needs.
Researchers define the atomic-level architecture of a protein-receptor connection that allows the malaria parasite to evade the immune response. A drug designed to fit into this space could block the interaction, allowing the immune system to clear away the pathogen and potentially reducing severe malaria cases.
A new study found that 48% of ICU staff showed signs of mental health conditions, including depression, insomnia, and PTSD. The study also found a significant increase in mental health issues among those who spent more than six hours in personal protective equipment.
Researchers have developed a new scoring system to evaluate wound healing in mice, using parameters such as re-epithelization and granulation tissue thickness. The system was validated in four different skin wound models, providing a more accurate and reproducible assessment of wound dynamics.
Fredrick Allan Clive Wright is the recipient of the 2021 IADR Distinguished Scientist Award in Geriatric Oral Research. He has made significant contributions to the knowledge of oral health in older people, general health relationships and effective geriatric oral care services.
A study evaluated self-reported protective behaviors and SARS-CoV-2 infection rates among in-person employees during the first six months of the pandemic. The research found a significant association between COVID-19 exposure and reduced compliance with public health guidelines.
A new study by Berkeley Lab and NREL found that optimizing building energy demand can significantly impact the electric grid. By increasing energy efficiency and flexibility in buildings, up to one-third of coal- or gas-fired power generation can be avoided. The regions with the largest grid resource are Texas, Southeast U.S., Great La...
YiPing Chen, a renowned developmental biologist, has made significant contributions to the understanding of genetic control and molecular regulation of mammalian organ development. He is recognized for his work on genetic regulation of tooth development and cleft palate, which have improved our knowledge of craniofacial biology.
A new study led by Bigelow Laboratory for Ocean Sciences suggests that the balance of chemical elements in plankton is primarily dependent on the ratio of nitrogen and phosphorus supplied from the subsurface ocean. This discovery could improve the accuracy of computer models used to forecast ocean change.
A new Dartmouth-led study found that white patients receive higher annual doses of prescription pain medicine than Black patients, even when treated by the same health system and team of clinicians. The researchers suggest that systematic racial bias is a major contributor to these disparities.
Research found that breastfeeding, even for a short period, is associated with lower blood pressure in toddlers. The study suggests that colostrum, rich in growth factors and immunologic components, plays a key role in shaping cardiovascular development during the newborn period.
Researchers develop open-source molecular detection method to track B.1.1.7 (Alpha) variant in wastewater, providing actionable community-level information for health authorities. The breakthrough expands utility of wastewater surveillance beyond SARS-CoV-2 testing.
Archaeologists found that the lack of a mutualistic relationship between humans and New World rabbits, characterized by controlled reproduction, prevented domestication. The solitary nature of American cottontails made it difficult for humans to control their population and evolution.
Researchers have made a groundbreaking discovery about the Sun's magnetic field, revealing that field lines become knotted before emerging at the visible surface. The findings provide conclusive evidence for one of two dominant theories explaining how solar activity occurs.
Ingegerd Johansson, a senior professor at Umeå University Medical School, was awarded the William H. Bowen Research in Dental Caries Award for her pioneering work on nutrition and dental caries. She has published over 300 scientific papers and mentored numerous students.
Hazem Abbas, a Ph.D. student at Tohoku University, Japan, received the IADR Lion Dental Research Award for his innovative research on social determinants of health and their relation to oral health outcomes. The award recognizes outstanding basic dental science research that aims to improve public dental health.
A study published by the American Academy of Neurology found that people with migraines experienced more dizziness and motion sickness during virtual roller coaster rides compared to those without migraines. Brain scans revealed abnormal nerve cell activity in areas responsible for visual processing and motor activity.
Dennis Sourvanos, a University of Pennsylvania graduate resident, received the AADR William B. Clark Fellowship for his work on novel biotherapies in hard and soft tissue regeneration. The fellowship supports clinical research in periodontology and aims to enhance evidence-based oral healthcare.
A new wearable brain-machine interface system allows users to imagine actions and wirelessly control wheelchairs, robotic arms, or other devices. The soft and comfortable wearable device offers improved signal acquisition and accuracy compared to existing BMI systems.
A phase 2 clinical trial found that ibrutinib is a safe and effective treatment option for patients with relapsed or variant forms of hairy cell leukemia. The study, conducted at Ohio State University Wexner Medical Center, showed improved cancer control for this high-risk patient group.
Research found a shift in how facemasks affect facial attractiveness among Japanese population, with reduced unhealthiness and increased neutral effects reported after pandemic onset. Mask color had no effect on perceptions.
Caroline Shiboski, a renowned oral medicine expert, has been awarded the IADR Distinguished Scientist Award for her groundbreaking research on immune dysfunction and its effects on oral health. Her work has led to significant advances in understanding and treating conditions like Sjögren's Syndrome and HIV-related oral diseases.
Researchers found that older people have lower antibody responses against COVID-19 variants, making them more susceptible to infection. Vaccination still appears effective in preventing severe illness, but promoting vaccinations is crucial to protect the community.
Congresswoman Rosa DeLauro has been recognized by the American Association for Dental Research (AADR) with its Honorary Membership. She is being honored for her strong advocacy of biomedical research, including efforts to increase funding for the National Institutes of Health (NIH).
A team of astronomers has made detailed observations of a large tidal flow around the Sombrero galaxy, revealing its strange morphology and shedding light on its possible merger history. The study's findings suggest that the galaxy's unusual shape may be due to cannibalism by a satellite dwarf galaxy.
Sarah Knox is recognized for her outstanding contributions to salivary research, with a focus on parasympathetic innervation and tubulogenesis in developing salivary glands. Her work has elucidated mechanisms of salivary gland development and regeneration relevant to tissue repair in autoimmune disease and cancer.
Bruno Loos, Academic Center for Dentistry Amsterdam, has received the IADR Distinguished Scientist Award for his outstanding research in periodontal disease. He is recognized for his contributions to the understanding of oral health and systemic health relationships.
A UNIGE team has identified important regulatory mechanisms of the protein responsible for chromosome separation. The study reveals that inhibitory proteins block separase activity by occupying sites that recognize the cohesin substrate, preventing cleavage.
A study by Curtin University found that people with low back pain are more likely to use a squat-like technique when lifting, contradicting existing advice. Researchers suggest a 'one size fits all' approach may not work and a more individualised approach may be required.
Researchers discovered that yeast changes hundreds of proteins' expression patterns and subcellular localizations after adapting to a higher temperature. The proteome's plasticity allows the cells to adapt by reducing thermolabile protein load, changing protein conformation, and adopting new functions.
This symposium explores the effects of environmental influences on enamel formation, including early life adversity, endocrine disruptors, and genetic susceptibility. Researchers highlight the importance of enamel as a biomarker for exposure to environmental stressors, potentially leading to increased dental disease risk.
Edward Chin Man Lo is the recipient of the 2021 IADR E.W. Borrow Memorial Award for his groundbreaking research on oral health prevention and caries prevention, with a focus on innovative approaches to fluoride utilization.
David Williams, Professor of Global Oral Health at Queen Mary University of London, received the 2021 IADR Gold Medal Award for his work on oral health inequalities. He has developed a Standard Set of Adult Oral Health Outcome Measures and is a key figure in promoting sustainable growth and better global health outcomes.
A new study identifies hundreds of chemicals that may increase breast cancer risk by stimulating hormone production. The chemicals include pesticides and ingredients in personal care products.
Researchers at Sandia National Laboratories have designed a new class of molten sodium batteries that operate at lower temperatures and use low-cost materials. The new battery design has the potential to significantly reduce costs and increase efficiency in grid-scale energy storage.
A team of researchers created an engaging program to educate children aged 8-14 about migratory fishes and aquatic environments. The Shout Trout Workout combines music, comedy, and lyrics to convey important ecological information in a fun way.
A Washington State University research team developed wearable wristbands to measure physiological responses to stress in real-time, providing a potential method to prevent relapses in people with Alcohol Use Disorder. The study found that the devices matched survey results and can trigger interventions when needed.
Researchers developed nanoparticles that absorb near-infrared light, creating heat and inhibiting electrical activity in neurons. The biocompatible and biodegradable nanoparticles offer a potential tool for controlling neuronal activity remotely.
Researchers found that masitinib inhibited SARS-CoV-2 viral loads and reduced inflammation in human cell cultures and mouse models. The drug also showed effectiveness against multiple variants, including Alpha, Beta, and Gamma, and other viruses such as picornaviruses.
A large-scale study by Brigham and Women's Hospital found that higher levels of physical activity and lower levels of sedentary behavior are associated with a lower risk of obstructive sleep apnea. The study suggests that promoting an active lifestyle may have substantial benefits for both prevention and treatment of OSA.
A new study by the University of Notre Dame links toxic pollution and climate risks to human health, with a focus on addressing these issues in countries most at risk. The study identifies the top 10 countries that require urgent attention, including Singapore, Rwanda, China, and India.
A new three-paper series published in The Lancet calls for immediate action to prioritize research and public health measures to improve physical activity worldwide. The authors highlight the need to address inadequate support for adolescents and people living with disabilities, who are disproportionately affected by physical inactivity.
A new study by University of South Australia researchers found that virtual reality leads to better recall, spatial accuracy, and more consistent verdicts. Participants viewing a 3D scene were 9.5 times more likely to choose the same verdict than those relying on photographs.
A new thumb-sized device can diagnose bad breath by sniffing out hydrogen sulfide gas in exhalations, correctly identifying it 86% of the time. The device combines a metal oxide gas sensor with humidity, temperature and pressure sensors.
The IADR/AADR presented awards to researchers in three categories: Biological Research, Biomaterials & Bioengineering Research, and Clinical Research. The winners were recognized for their contributions to advancing dental health and well-being worldwide.
Researchers at CU Boulder's ATLAS Institute have developed shape-changing objects inspired by origami that can bend, wiggle, and flutter using artificial muscles. The 'Electriflow' designs utilize hydraulically amplified self-healing electrostatic actuators to create paper-thin, fast-moving, and almost silent objects.
The study reveals that the structure of cytolysin subunits is crucial for their activity, with macrocycles playing a key role in stabilizing the molecule. The researchers also identified a hinge region important for the subunit's shape and membrane penetration capabilities.
A randomized trial in Bangladesh shows that training in the System of Rice Intensification (SRI) method increases rice yield and profit by 14-17% and 22-31%, respectively. Additionally, household well-being is higher for farmers in training communities compared to those without training.
The International Association for Dental Research awarded Adetomiwa Adedire a $2,500 fellowship to explore the effect of Massularia Acumiinata on volatile sulphur compound concentrations and tongue pH. The award supports dental research in health and well-being worldwide.
Forensic scientists have developed a new method using Easylift tape to collect and analyze microplastic samples, improving efficiency and accuracy. This technique enables multiple analytical techniques to be applied to the samples afterwards and preserves them for future study.
Daniel McNeil, a renowned psychologist at West Virginia University, has been recognized with the IADR Distinguished Scientist Award in Behavioral Epidemiologic and Health Services Research. His work focuses on psychosocial factors, pain, dental fear, anxiety, and phobia, making significant contributions to our understanding of health.
The study found that two-dose mRNA vaccines provided 88% protection against the original SARS-CoV-2 virus, 86% against the Alpha variant, and 77% against the Beta variant. Previous SARS-CoV-2 infection also conferred similar protection to mRNA vaccination.
Fionnuala Lundy, an Associate Professor at Queen's University Belfast, has received the IADR Distinguished Scientist Award for her groundbreaking research on naturally-occurring antimicrobial peptides. Her work focuses on oral/dental stem cells, pulp regeneration and various oral diseases.
Scientists at the La Jolla Institute for Immunology have discovered that Vitamin C and TET proteins can work together to generate stable induced Tregs, which could potentially treat autoimmune diseases. The study reveals an intriguing connection between TET enzymatic activity, Vitamin C and IL-2/STAT5 signaling.
A Lehigh University team is working on a culturally tailored program to reduce American Indian smokeless tobacco use, supported by a $1.8 million grant from the American Cancer Society. The All Nations Snuff Out Smokeless (ANSOS) program aims to empower individuals to take control of their health.
New research from the University of Illinois explores how community characteristics impact the relocation of toxic-releasing facilities. The study found that facilities are more likely to move from communities with high population density, income, and education levels, while moving into those with lower socioeconomic status.
A study from the University of York found pregnant women in South East Asia are more likely to use smokeless tobacco than non-pregnant women. This increased risk is associated with poor birth outcomes. The findings highlight the need for awareness-raising campaigns and preventive interventions among low socio-economic status women.
May Wong, Professor of Dental Public Health at the University of Hong Kong, was awarded the IADR Distinguished Scientist H. Trendly Dean Memorial Award for her significant contributions to dental research. Her work focuses on biostatistics, oral epidemiology, and clinical trials.
Two recent studies link EBV reactivation to long COVID symptoms and severe COVID-19 cases. Researchers found that nearly 73% of patients with long COVID were positive for EBV reactivation, suggesting a potential role for the virus in the development of these symptoms.
Researchers at USC have developed a new simulator that accurately predicts the forces acting on a knife as it cuts through soft materials, enabling applications in safer food processing and surgical robotics. The system uses 'differentiable' simulation to automatically tune parameters from real-world measurements.
Alastair Sloan, Head of School at the Melbourne Dental School, has received the 2021 IADR Isaac Schour Memorial Award for his significant contributions to tissue engineering and dental biology. He was recognized for his work on regeneration of mineralized tissues and behavior of dental pulp stem cells.
Researchers from HSE University have discovered a nucleotide sequence characteristic of microRNA isoforms, which helps predict errors in microRNA behavior. This discovery has important applications for creating drugs that can detect targets more effectively.
A study of 19,862 Japanese participants aged 65+ used machine learning to analyze oral and general health. The analysis found robust associations between self-rated oral and general health, with oral health predicting general health more accurately than vice versa.
Researchers at ETH Zurich developed a new chip-based test that incorporates the placenta into embryotoxicity assessments. The test detects indirect damage to embryos by analyzing stress responses of human placental cells to toxic substances.
Researchers have created a blood test that can predict COVID-19 severity, which could aid in prioritizing patients for hospitalization. The test uses attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) to measure changes in blood biochemistry and has shown promise as a rapid and simple triaging tool.
Researchers have discovered protein markers related to chronic lymphocytic leukemia (CLL), a common form of leukemia. The markers can help determine patients' prognoses and point to potential therapeutic targets.
Clinical ethicists discuss activist language and its impact on healthcare crises, including triage policies and racial disparities. The article highlights four calls to action: recognizing barriers, supporting antiracism work, advocating for policy change, and engaging in institutional activism.
The new allocation system could result in reduced access to kidney transplants and longer wait times for patients in South Carolina. Researchers argue that the current system unintentionally worsens inequities and recommend improving access to transplant care.
Research found that patients with ICDs who increased physical activity outside of cardiac rehab experienced fewer hospitalizations and lower death rates, with every 10 minutes of added activity reducing death risk by 1.1%
Ting Zou, a postdoctoral fellow at The University of Hong Kong, has been awarded the IADR Toshio Nakao Fellowship for her research on multifunctional hydrogels and tissue regeneration.
Eric Everett, a renowned researcher, has received the IADR Distinguished Scientist Award in Biological Mineralization Basic Research. His work focuses on craniofacial and mineralized tissue genetics, gene-environment interactions, and animal models for dental and oral disorders.
Investing in structural home repairs in historically segregated, low-income neighborhoods has been associated with reduced crime rates and improved public health. Research from the University of Pennsylvania found that total crime dropped by 21.9% on blocks where homes received repairs through a city-funded program.
Researchers developed a new framework using machine learning that improves the accuracy of interatomic potentials for designing new nanomaterials. The findings suggest a positive correlation between the complexity and number of parameters and the accuracy of interatomic potential.
Researchers simulated the hydrodynamic behavior of deep-sea Venus flower sponge E. aspergillum, revealing its skeletal adaptations optimize flow physics within and beyond its body cavity. The findings improve understanding of mechanical and biological responses to dynamic forces.
A study published in Ibis found that Golden Eagles avoid wind turbines due to habitat loss, affecting their suitability inside and outside of wind farms. The largest impact of wind farms was the loss of Golden Eagle habitat, which could be mitigated by incorporating the findings into wind farm planning.
A study of 1,175 Polish parents found that about 13% regret having children, linked to poorer psychological and physical health. Parental burnout, social pressures, and financial status also play a role in this phenomenon.
Regular physical activity and reduced sedentary behavior are linked to lower risk of obstructive sleep apnea (OSA). Studies found that exercising for just two hours a week can lower OSA risk by 54%, while spending less than four hours watching TV daily reduces the risk by 78%. Increasing physical activity in leisure time or reducing se...
Rachel Volberg, a UMass Amherst professor, has received the National Council on Problem Gambling's Lifetime Research Award for her 35-year contributions to problem gambling research. Her studies on Massachusetts casinos' social and economic impacts are considered groundbreaking.
Lauren Katz, a postdoctoral researcher at UNC Chapel Hill, received the IADR Osteology Foundation New Investigator Award for her work on craniofacial skeletal muscle regenerative potential. Her goal is to develop therapeutic options for patients with congenital and acquired craniofacial defects.
A study of consumers with food allergies found that less than half understood allergy information on food labels, attributing varying levels of comprehensibility assessments. Precautionary statements have little value for consumers and may lead to inappropriate dietary restrictions or risk-taking behavior.
Three-quarters of surveyed trans and gender diverse Australians experienced at least two negative encounters with gender insensitivity in sexual health care. The survey found significant associations between cisgenderism, testing for HIV and other STIs, and poor healthcare outcomes.
Researchers have discovered a unique quantum physics signal known as the 'layer' Hall effect in a solid-state chip made of antiferromagnetic manganese bismuth telluride. The finding signals the presence of a sought-after topological Axion insulating state, a feature bound by quantum physics laws.
A team from UNIGE and HUG used information theory to study the molecular regulations behind cancer cell adaptation to targeted therapies. They found that a large reversible component of resistance exists, which can be modulated by therapeutic combinations.
New analysis of 71 years of data reveals that Santa Ana wind fires are largely driven by powerline ignitions and wind speeds. Ignitions account for all fires during these events, with powerline failures being a major contributor to land area burned.
Researchers at the University of Illinois have developed a new compound called ErSO that kills 95-100% of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases. The compound targets the anticipatory Unfolded Protein Response pathway, which is already active in many breast cancer cells.
Navdeep Kaur Brar has been awarded the IADR John A. Gray Fellowship to support her research on antibiotics and microbiome impact. The $10,000 fellowship aims to provide training and experience in dental or related research.
The American Association for Dental Research (AADR) has announced the winners of its 2021 411 Rapid Research Competition. In the Basic Science category, Juhi Uttamani from the University of Illinois at Chicago won first place with her research on miRNAs in periodontal inflammation, while Mary Younan from the University of Texas took se...
Researchers chronicle African dust transport across North Atlantic, highlighting its essential role in marine and terrestrial ecosystems. The study also explores the link between dust transport and African climate, shedding light on Earth's largest source of dust.
Spotted hyenas inherit advantageous social networks from their mothers, which affect their health and longevity. Higher-ranking mothers imprint these networks on their cubs more accurately, leading to longer life and reproductive success.
Researchers identified six novel molecular subtypes of thymic epithelial tumors that are independent of World Health Organization histologic type. The study used genomic information from The Cancer Genome Atlas dataset and the IU-TAB-1 cell line, and found no association between WHO histologic subtype and molecular subtypes.
Researchers observed signs of spin-triplet superconductivity in magic-angle trilayer graphene, which resists high magnetic fields and could improve MRI technology. This exotic material's ability to persist superconducting under strong magnetic fields has the potential to revolutionize technologies like quantum computing.
Lois Cohen, a renowned researcher, has been awarded the IADR Distinguished Scientist Award in Global Oral Health Research. Her extensive career has spanned over 55 years and focused on linking behavioral and social sciences to public health issues.
A new study reveals that older people are slower to learn actions and behaviors that benefit themselves, but are just as capable as younger people of learning behaviors that benefit others. When making choices that give positive feedback to another person, older adults' learning ability is preserved.
Kiyoshi Koyano, a renowned prosthodontist, has received the IADR Distinguished Scientist Award for his outstanding research contributions to the field of prosthodontics and implants. He is recognized as a prominent scientist in Japan, with numerous international positions and publications on clinical practice and prosthodontics.
Hazem Abbas, a Ph.D. student at Tohoku University, Japan, received the IADR Lion Dental Research Award for his research on social determinants of health and their relation to oral health outcomes. The award aims to support improvements in oral health sciences through innovative research.
A survey of over 650 astronomers and geophysicists reveals a systemic bullying problem, with disabled and black/minority ethnic individuals facing higher rates of bullying. Women and non-binary individuals are also more likely to experience bullying and harassment in the workplace.
A team of researchers has uncovered the intricate cellular mechanism behind calcium's role in regulating energy supply to specific brain regions. By studying calcium signals in capillaries, they found that increased calcium levels trigger nitric oxide production, leading to vessel relaxation and enhanced blood flow.
Researchers analyzed 1.95 million family units, finding a low overall rate of misattributed paternity (1.7%) with rates closer to 1% in recent decades. The study's findings suggest that misattributed paternity is unlikely to have significant effects on hereditary condition studies.
A study published in Nature Communications reveals the visual system retains information from moving images, providing a consistent representation of surroundings. The researchers found that neuronal responses in deeper layers of the visual cortex exhibit 'perceptual constancy' and 'intrinsic persistence', ensuring stable encoding and ...
Current carbon capture technologies require significant energy output, making them less than optimal. Researchers are working on developing more efficient methods using solid sorbents and membranes, which already show promise in concentrated CO2 emissions sites.
Twenty-nine percent of Americans increased supplement use during the pandemic, citing enhanced immunity and overall well-being as reasons. Despite this, many people are unaware of the risks and safety issues associated with supplement use, according to a survey conducted by The Harris Poll on behalf of Samueli Foundation.
A group of leading doctors and health experts warn that the UK government has failed to deliver on its promise to make England smoke-free by 2030. The smoking rate remains high, with over 200,000 children under 16 starting to smoke in the last two years.
The American Association for Dental Research recognized Ning Yu, a researcher at The Forsyth Institute, for her contributions to periodontal research. Yu received the $10,000 USD fellowship to support women researchers in early stages of their careers and promote diversity in the field of oral biology.
A global consensus statement identifies key issues in healthcare for people living with HIV, prioritizing multimorbidity, health-related quality of life, and stigma reduction. The panel recommends new monitoring processes and guidelines to ensure the long-term well-being of millions worldwide.
A team of scientists proposes a way to control all properties of photonic qubits using modulated quantum metasurfaces. This technology could enable secure communication, sensing and imaging, as well as harnessing energy from photons.
Researchers have created a dynamic model that accurately recreates hemodynamic loads on engineered heart muscle tissues, providing unprecedented insights into how genetics and mechanical forces contribute to heart muscle function. This breakthrough model allows for the study of various heart diseases with genetic mutations, development...
The study contributes to deciphering genetic background of unique marsupial characteristics by creating genetically modified opossums. The researchers successfully edited a gene responsible for body pigments, producing albino offspring with inherited genes.
Patricia Miguez, a tenure-track Assistant Professor at the University of North Carolina, Chapel Hill, has won the AADR Procter & Gamble Underrepresented Faculty Research Fellowship. The fellowship supports her research on the extracellular matrix and its modifications in health and disease, with a focus on craniofacial region.
A team of chemists from Waseda University in Japan has synthesized aryl sulfides without using thiols, a toxic and smelly compound. The new method uses a nickel catalyst and environmentally friendly aromatic esters as feedstock, showing promise for both laboratory and industrial-scale applications.
Researchers studied dairy cow behavior by making them walk in a straight line to identify optimal gaits. The study provided valuable insights into kinematic characteristics of normal gait, enabling the development of more efficient breeding programs.
Researchers identified cardiovascular test results that may indicate high-risk COVID-19 patients, including low left ventricular ejection fraction and tricuspid annular plane systolic excursion. These findings suggest clinical parameters can help predict in-hospital mortality for COVID-19 patients.
Scientists have developed a new model to predict the health of coral reefs using data from the Khaled bin Sultan Living Oceans Foundation's Global Reef Expedition. The model identifies key drivers of coral reef health, including biophysical and anthropogenic factors.
Researchers found that Papua New Guinean highlanders have physical traits counteracting hypoxia, such as smaller height and waist, larger lung volume and chest depth, and higher haemoglobin concentration compared to lowlanders. These adaptations may be a result of living at altitude for 20,000 years.
PlantwisePlus will test new interventions in 6-7 countries to reduce crop losses and empower farmers to increase incomes, food security, and food safety through sustainable approaches. The program aims to accelerate the availability of nature-positive plant protection products and create employment to support economic development.
A study analyzed 11 years of data to find that 37% of Congress members own or have owned healthcare-related assets. The average value of these assets was $43,000, indicating a significant potential for conflicts of interest.
A study in the Journal of School Health monitored 1,154 students for asymptomatic COVID-19 cases during high community transmission. The researchers found no transmission linked to bus transportation, despite near-capacity operations with universal masking and ventilation.
A new randomized controlled trial found that Transcendental Meditation significantly improved emotional stress symptoms, quality of sleep, and English Language Arts academic achievement in high school students. The study showed that meditation was more effective than sustained silent reading in improving academic outcomes.
The project aims to identify potential environmental costs of deep-sea activities to inform responsible use. It will connect diverse science and policy experts in industry, academia, and private institutes to guide sustainable practices.
Researchers at Weill Cornell Medicine have discovered that injecting mice with pulmonary endothelial cells can reverse the symptoms of emphysema. The study found that targeting endothelial cell function may represent a strategy for treating patients with advanced COPD or emphysema. Injecting healthy lung endothelial cells and/or inhibi...
Researchers have found a material that exhibits superconducting properties at extremely low temperatures, providing new insights into high-temperature superconductivity. The discovery was made by studying an unusual 'strange metal' called YbRh2Si2, which showed linear resistance and temperature relationships.
The B.1.617 variant infects lung and intestinal cells more efficiently than the original virus, reducing antibody effectiveness in protecting against infection. This may lead to increased transmission among vulnerable populations.
A new tool called the 'scene wheel' is being used to study how accurately people construct mental representations of visual experiences. The wheel uses highly realistic images and deep-learning methods to simulate everyday visual experiences, allowing researchers to test the validity of classic findings in the field.
Karan Jani's Gravitational-Wave Lunar Observatory for Cosmology aims to analyze black hole and dark matter mergers with unprecedented sensitivity. The moon's environment offers an ideal backdrop for the observatory, lacking atmosphere and seismic noise, making it a crucial step towards discovering new physics.
A recent study published in the New Zealand Journal of Ecology found that alpine-based hedgehogs hibernate in the same areas they used in summer and do not migrate to lower elevations. This discovery suggests that hedgehogs are residents in these zones, rather than just visitors.
Gender-affirming hair removal procedures were associated with reduced rates of past-month severe psychological distress, past-year smoking, and past-year suicidal ideation. The study analyzed data from the 2015 U.S. Transgender Survey.
A new analysis reveals that global toxic pollution and climate change disproportionately affect low-income countries, with the top-one-third of at-risk nations accounting for over two-thirds of the world's population. The study provides a list of top-ten countries most equipped to immediately begin risk reduction efforts.
A new recipe combining chickpea flour and psyllium has resulted in a more nutritious and acceptable gluten-free bread. The product contains high amounts of fiber, proteins, vitamins, and minerals, and has been rated highly by consumers in qualitative surveys.
A University of Otago study reveals that high proportions of renewable generation coupled with energy storage is technically and economically viable for Samoa's electricity system. The results show that setting targets below 100% and considering biomass options can make renewable energy more attractive and affordable.
Researchers found that wearing exoskeletons while performing tasks requiring mental effort can lead to brain overwork and decreased efficiency. The devices may not be as effective as initially thought in alleviating stress on lower backs.
A new testing capability has been developed at Sandia National Laboratories to simulate multiple environments on a full-scale weapons system, producing richer data and improving test repeatability. This allows engineers to validate weapon design and systems performance more efficiently.
A randomized clinical trial found that semi-annual application of 5% sodium fluoride varnish significantly reduces approximal caries development in primary teeth compared to 38% silver diamine fluoride and placebo controls. The study evaluated 4-6 year-old children with at least one sound approximal surface.
A study by Max Planck Institute researchers found that bacteria on sand grains in the North Sea and Arctic remain consistent throughout seasons. The community's stability suggests a lack of available space for new inhabitants.
Researchers simulated 3 million swimming race times to show that certain quartzite oscillator-based devices round times incorrectly. This can result in changes of one one-hundredth of a second, potentially affecting the outcome of sporting events.
A new perspective piece highlights the need for a more complex approach to defining carbohydrate quality, considering nutrient intakes, balanced diets, and environmental impact. The authors propose several potential quality indices, including whole-grain, fiber, and protein content, to establish a standardized metric.
Rosa, an Associate Professor at NUS Faculty of Dentistry, received the award for his work on atom-thin materials for biomedical applications and dental pulp regeneration. He will serve a two-year term on the IADR Board of Directors.
Scientists use infrared sensors to study the nighttime weather of Venus, discovering that north-south winds run in the opposite direction at night. This observation could help build more accurate models of the Venusian weather system and provide insights into Earth's weather patterns.
Engineered nanostructures overcome problems in gas-based high-harmonic generation, enabling scientists to observe molecular dynamics with a single laser shot. The record-breaking conversion efficiency covers a wide range of photon energies, opening up new opportunities for studying matter at ultrahigh fields.
Scientists at St. Jude Children's Research Hospital have found a link between post-cancer treatment frailty and neurocognitive decline in young adult childhood cancer survivors. Frailty contributes to early onset of neurocognitive decline, which can influence daily activities.
A new clinical trial aims to test a personalized treatment for severe asthma targeting a specific mutation found disproportionately in people of color. The trial, led by Boston Children's Hospital, will test dupilumab, an existing drug that blocks the mutated IL-4 receptor, in patients with and without the mutation.
A study of 1,741 women and 620 men aged ?65 years found that cognitive decline is linked to accelerated bone loss and a higher risk of fractures in women. The bidirectional relationship between bone loss, cognitive decline, and fracture risk suggests shared underlying factors.
Research at North Carolina State University reveals that soil microbes significantly impact heterosis, or hybrid vigor, in corn plants. In experiments with sterile bags and field tests, hybrid lines outperformed inbred lines due to microbial effects on root growth and biomass.
A new saliva collection method involves self-collection by licensed dentists followed by mailing to a laboratory, demonstrating feasibility for large-scale analysis. This approach offers a cost-effective alternative for COVID-19 diagnostics, preserving saliva samples for up to 7-10 days at room temperature with stabilizers.
Christopher Murray, a renowned physician and health economist, has been recognized for his significant contributions to global oral health. His work on the Global Burden of Disease project has led to improved understanding of the impact of dental diseases on disability-adjusted life-years worldwide.
Nisha D'Silva, a University of Michigan professor, is recognized for her exemplary mentoring skills, having mentored over 60 students and post-doctoral fellows in oral pathology and cancer biology.
Martha Somerman received the AADR Jack Hein Public Service Award for her exemplary work promoting oral health research to a wide constituency. She has over 150 peer-review publications and contributed to 20 books or book chapters.
A study by Portland State researchers found that liberals see climate science as certain and simple, while conservatives view it as uncertain and complex. Conservatives prefer to share their own experiences with the effects of climate change rather than receiving more information from experts. This shift in perspective may help people ...
A new study found that extract made from fermented soybean dish natto inhibits the ability of SARS-CoV-2 to infect cells, while a heat-treated extract showed no effect. Researchers believe this could lead to pharmaceutical design for COVID-19 treatments.
A collaboration has created a first-ever simulation of the deep-sea Venus basket sponge, revealing its ability to withstand dynamic forces and create nutrient-rich vortex within its body cavity. The structure of the sponge is optimized for fluid flow, reducing drag and facilitating feeding and reproduction.
The International Association for Dental Research (IADR) has announced the 2021 recipients of the IADR Innovation in Oral Care Awards. The awards recognize innovative oral care technologies that will impact public health and quality of life. This year's winners, funded by GlaxoSmithKline, will receive $50,000 USD each.
Native Mediterranean species have been found to prey on the invasive Pacific red lionfish and silver-cheeked toadfish, suggesting direct human management measures are needed to control their populations. The study documents native predators for both species, including loggerhead turtles and dolphinfish.