Research found maternal obesity reduces placental formation, blood vessel density, and nutrient exchange capacity. Both obesity and gestational diabetes impact placental hormone production and inflammation markers.
Researchers found that breathing muscle strength persisted for five weeks after training stopped, suggesting potential benefits for physical endurance and quality of life in individuals with chronic lung conditions. Inspiratory muscle training also reduced the metaboreflex, allowing for improved exercise endurance.
Researchers found that poorer blood sugar control, as measured by haemoglobin A1c, was associated with higher core body temperature and increased heart rate during exercise in a heated chamber. This suggests that people with type 2 diabetes may be at greater risk of heat-related stress and heat-related injuries.
A high fat diet can disrupt the brain's ability to regulate calorie intake by affecting astrocytes, which control signaling pathways between the brain and gut. This can lead to overeating and weight gain. Understanding this mechanism could help develop therapies to treat obesity.
Research suggests that six minutes of high-intensity exercise can increase the production of brain-derived neurotrophic factor (BDNF), a protein essential for brain formation, learning, and memory. BDNF promotes neuroplasticity and neuronal survival, potentially delaying age-related cognitive decline.
Research found that 'night owls' are more insulin resistant, favoring carbohydrates over fats as an energy source. In contrast, 'early birds' are more active and use more fat for energy, reducing their risk of type 2 diabetes and cardiovascular disease.
A new study found that early life exposure to antibiotics in neonatal mice has long-lasting effects on their microbiota, enteric nervous system, and gut function. This could mean that babies given antibiotics may experience gastrointestinal issues later in life.
A new study shows that low-dose dexamethasone helps premature babies develop lungs without harming their hearts. The treatment reduces respiratory support requirements and improves blood circulation to the lungs, leading to better cardiorespiratory outcomes.
Researchers have discovered that Piezo1 is responsible for regulating the uterus's behavior during pregnancy, keeping it relaxed and ensuring proper expansion. The identification of Piezo1 paves the way for developing drugs and therapies to treat or delay preterm labour, a major cause of neonatal mortality and morbidity.
Breathing difficulties following opioid use can be fatal. Electrical pulses to the back of the neck have been found to help patients regain respiratory control and breathe independently without the need for medication or mechanical assistance.
A study found that maternal obesity impairs heart health and function of the fetus, altering gene expression and increasing risk of cardiac problems in later life. Sex differences were observed, with females experiencing impaired cardiac function that worsened with age, while males showed impairments from birth.
Research published in The Journal of Physiology highlights the benefits of lifelong exercise on muscle health in older adults. Elderly individuals who engage in regular physical activity throughout their life have healthier ageing muscles with superior function and resistance to fatigue.
Research suggests women with lingering COVID-19 symptoms experience heart rate irregularities during physical exertion, leading to delayed recovery and reduced exercise tolerance. Targeted rehabilitation programs are needed to manage these consequences in women with persistent heart and lung problems.
A new study found that ketone supplements enhanced blood flow to the brain and improved aspects of cognitive function, such as working memory and processing speed, in adults with obesity. This suggests that ketone supplements may be a novel therapeutic strategy for protecting and improving brain health in people with obesity.
A new study found that a healthy gut microbiome is essential for skeletal muscles to grow after exercise. Researchers used mice with antibiotics to disrupt the microbiome, showing reduced muscle growth compared to healthy mice. The findings support previous studies linking the gut microbiome to muscle health.
Researchers found that high-fat diets disrupt the body clock's satiety control, leading to overeating and obesity in rats. The study suggests that restoring the proper functioning of the body clock may help tackle obesity.
Research found that COVID-19 affects sympathetic nervous system activity, leading to abnormal heart rate and blood pressure responses. This alteration may have long-term implications for cardiovascular health in older adults.
New research reveals that acute exercise can slow down the growth of bowel cancer cells by releasing proteins into the bloodstream. This finding suggests that regular physical activity may lower the risk of developing bowel cancer, even in individuals who do not experience weight loss.
Research by Tanja Oosthuyse and colleagues found that protein hydrolysate supplements improved training intensity in women, but not in men, during carbohydrate-restricted exercise. In contrast, the supplements made exercise feel harder for men due to increased breakdown of the supplement.
A new study published in The Journal of Physiology shows that two existing medications can reduce sleep apnoea severity by up to one third. Almost everyone who participated in the study showed some improvement, with increased muscle activity around the airway and reduced breathing stoppages.
A study published in Experimental Physiology found increased stiffness of arteries in young adults after COVID-19, potentially leading to cardiovascular complications. The researchers are following the participants for 6 months to observe any improvements or long-term effects.
Low-volume HIIT (less than 20 minutes total exercise time) yields comparable improvements to longer interventions despite requiring significantly less time. This approach is especially beneficial for individuals with busy schedules who struggle to meet current physical activity guidelines.
A new study suggests that temperature scanners are unreliable for detecting Covid-19 due to false negatives and varying factors affecting skin temperature readings. Taking temperature readings from a person's fingertip and eye can provide a more reliable indicator of fever-induced changes in deep body temperature.
A new study published in The Journal of Physiology found that hand-eye coordination is impaired by more than 20% at BAC levels as low as 0.015%, even below the legal limit for driving.
The conference shares current knowledge and thinking across physiological systems, showcasing the symbiotic relationship between physiology and critical care. Physiologists have played an integral part in managing COVID-19, highlighting the importance of understanding pathophysiology to drive appropriate clinical intervention.
A new study published in The Journal of Physiology found that administering a low dose of ketamine to healthy individuals does not alter their ability to tolerate simulated major blood loss. This study provides valuable insights for medical personnel when choosing pain medication for serious injuries with accompanying blood loss.
Researchers have identified separate brain pathways for good and bad coughs, potentially leading to new treatments for chronic cough disorders. The study used functional brain imaging to assess cough reflex sensitivity and identified two distinct neural circuits involved in coughing.
Research reveals that older adults are less able to regulate body temperature and hydration during exercise in hot environments due to decreased sensitivity to elevated blood osmolality. This can lead to increased risk of heat-related injuries and adverse heart problems, highlighting the importance of staying hydrated.
A new study published in the Journal of Physiology found that exercising before menopause is crucial for women to develop blood vessels in muscles and improve muscle strength. The research revealed that capillaries in skeletal muscle are essential for physical capacity, health, and insulin sensitivity, which can lead to Type II diabetes.
Research shows that oxytocin reverses delayed gastric emptying caused by stress, increasing stomach muscle contractions. The hormone also inhibits adaptation to stress, delaying gastric emptying and decreasing stomach tone.
New research shows that nitrate improves diaphragm function by increasing power, which could help elderly individuals clear lungs more effectively. This finding is significant, especially in the context of COVID-19, as the diaphragm plays a crucial role in breathing and coughing.
A new study found that prenatal Viagra treatment worsened growth-restriction in baby sheep by impairing the fetus' ability to redirect blood flow to essential organs. This impairment occurred despite lower levels of oxygen in the fetal blood, suggesting a potential mechanism underlying increased morbidity observed clinically.
A new study found that acute exercise maintains the immune system's natural killer cell count at a normal level in prostate cancer survivors. Exercise appears to be safe and beneficial for these individuals, with no significant alterations in immune cell mobilization during treatment.
A new study found that consuming whey protein at night increases blood sugar levels in the morning for healthy individuals. This unexpected result may help inform strategies to improve blood sugar control, but further research is needed to confirm its applicability to other populations.
Research shows that plant proteins like soy and wheat can help maintain skeletal muscle mass with age, but a larger dose is required to achieve the same effect as animal protein. A balanced diet that includes both animal and plant-based proteins is recommended for optimal muscle health.
A new study found that 12 weeks of passive leg stretching improved blood flow and reduced stiffness in arteries. This non-invasive technique could serve as a new drug-free treatment for improving vascular health and reducing disease risk.
A new study suggests that misfolded protein build-up in the gut may contribute to Alzheimer's-like symptoms in mice, potentially leading to a new treatment approach targeting the gut. The researchers found that beta amyloid proteins injected into the gut traveled to the nervous system and brain, causing cognitive impairments.
Research shows that just one 60-minute bout of exercise can shift the muscle clocks of mice by around an hour, influencing circadian rhythms. This discovery highlights the potential of exercise as a treatment for conditions like heart disease, where disrupted body clocks are a contributing factor.
A new study published in Experimental Physiology found that fire service instructors experience higher levels of inflammation, which may lead to chronic health problems. The researchers suggest limiting their exposure to nine times per month to reduce the risk of cardiovascular disease.
Targeting the brain's control of breathing may help improve breathing in patients with respiratory disorders like COVID-19. Researchers found that reducing neural inflammation can minimize lung injury effects.
Research shows female mice accumulate more liver fat than males but are better at using it up, potentially benefiting women's health. Fasting may be beneficial for women specifically due to its impact on liver health.
Researchers found that increasing small blood vessels, rather than just improving circulation, could aid recovery from movement difficulties. The study uses a rat model to show that growing more capillaries is a new treatment option for conditions like heart disease and diabetes.
Researchers have identified a potential new treatment for chronic pain caused by burns, targeting PAK1 molecule. The discovery of Romidepsin, an existing cancer drug, provides a promising avenue for re-purposing to treat long-lasting complications.
A new blood test has been developed to measure microRNAs in children's blood, which can indicate sufficient or inadequate sleep. This test may provide a more reliable metric for assessing sleep hygiene and predicting susceptibility to various health conditions.
Researchers found that a weekly multi-modal regime combining physical and cognitive exercises significantly improved motor and non-motor symptoms in Parkinson's patients. The study suggests tailored exercise programs could improve quality of life for those affected by the disease.
Researchers at Liverpool John Moores University compared two popular HIIT protocols, finding that 60-second intervals with 60-second rest periods improved aerobic capacity and body composition. In contrast, 30-second intervals with 120 seconds of rest had no significant impact on fitness parameters.
Research shows air pollution harms hearts in humans and marine species through similar mechanisms, with PM2.5 being a major contributor to increased risk of coronary heart disease and stroke. The study highlights the importance of reducing air pollution to protect human health.
After just two weeks of reduced physical activity, older adults experience significant losses in muscle mass and strength, as well as gains in body fat percentage. This can lead to a reduction in cardiorespiratory fitness and mitochondrial function, which are critical for maintaining healthy muscles and metabolic health.
A new study confirms breastfeeding is crucial for preventing diabetes, as early weaning increases insulin secretion and susceptibility to Type 2 diabetes. The research suggests that not breastfed rat pups are more likely to develop insulin resistance and the adult form of the disease.
Changes in heart rate due to low oxygen conditions during pregnancy may predict future heart health, according to research published in the Journal of Physiology. The study used sheep models to examine the impact of chronic hypoxia on fetal heart development and identified potential markers for long-term heart disease risk.