New research shows that regular muscle stretching can improve blood flow to muscles of the lower leg in elderly people with reduced mobility. This non-invasive exercise technique may help alleviate lower leg problems, such as pain or weakness, and increase walking function in individuals with peripheral artery disease.
Research published in The Journal of Physiology suggests that shifting brain clock through light exposure can improve sleep quality and health benefits for night shift workers. A personalized approach considering individual morning or evening types is essential.
Researchers have discovered that muscle wasting in old age follows changes in the nervous system, which can be reversed with healthy muscles. The study found that surviving nerves can send out new branches to rescue detached muscle fibers, but this process is not successful in everyone.
Research found that fetal exposure to high-fat diets can lead to fatty liver development, increasing the risk of childhood obesity and metabolic diseases. The study identified microRNAs playing a role in this process, shedding light on potential strategies to combat childhood obesity.
Changes in neuron size have been linked to the progression of motor neurone disease, with vulnerable neurons increasing in size before symptoms appear. This could lead to new strategies for slowing or halting nerve cell death and improving treatment options.
Research reveals that high blood pressure impairs the body's response to hypoxia, limiting oxygen delivery to vital organs and tissues. Middle-aged men with high blood pressure were found to have reduced blood flow to the brain and leg muscles during low-oxygen conditions.
Researchers have discovered a key mechanism enabling stroke survivors to lift affected arms by tapping into 'backup' motor systems, bypassing damaged regions. This adaptive strategy involves involuntary activation of the elbow flexor muscles, which can be harnessed for improved movement control.
A ketone ester supplement has been shown to lower blood sugar levels in healthy individuals by reducing spikes in sugar consumption. The study used a single drink containing 75 grams of sugar and found that the ketone drink reduced the blood sugar spike compared to a placebo.
Research published in Experimental Physiology found that Bikram yoga, practiced at room temperature, shows similar benefits to traditional yoga for vascular health and atherosclerosis prevention. The study isolated the effects of heat on Bikram yoga, finding no benefit from heated environment.
Research published in The Journal of Physiology found that elderly people walk at a slower speed and tire more quickly due to muscle loss. Building up leg muscles may be the only way to improve elderly walking, according to the study's findings.
A recent study found that complete inactivity has a greater impact on the muscle power of older people than young individuals. This loss of muscle mass is more pronounced and can lead to increased decline in metabolic health and functional capacity.
New research suggests that a diet low in branched-chain amino acids (BCAAs) may improve metabolic health and promote leanness. The study found that obese mice on a specialized diet experienced improved glucose metabolism and energy expenditure despite not reducing overall calorie intake.
Researchers have found a potential new treatment for fetal growth restriction, a condition where the fetus doesn't grow at a normal rate during pregnancy. The treatment involves injecting a growth factor into sheep fetuses, which increased their growth without increasing stillbirths or deaths.
Research published in Experimental Physiology found that spinal cord injury affects the heart, with changes dependent on injury severity. The study suggests preserving more nerve fibers can improve heart function in individuals with spinal cord injury, who are at higher risk of heart disease.
People born prematurely may experience impaired lung function due to smaller airways. Researchers measured lung function at rest and during exercise to estimate airway size, finding it was smaller in premature groups.
New research finds that eating breakfast decreases genes involved in fat metabolism and increases sugar uptake in fat cells. This may lead to lower diabetes and cardiovascular risk in obese individuals.
Research found that eating fat at night leads to higher blood fat levels, a risk factor for heart disease and diabetes. The study's findings suggest ignoring the body's natural 24-hour cycle can harm health.
Research finds that late preterm babies, born at 35 weeks, are more likely to develop altered heart control and increased cardiovascular disease risk. Adult premature males also show decreased blood pressure regulation.
Researchers found that massage increased muscle growth after loss and improved protein manufacture in cells, leading to faster regeneration. Additionally, non-massaged muscles showed accelerated growth, suggesting massage could benefit both injured and healthy limbs.
A new study published in The Journal of Physiology found that pregnant women who sleep on their backs during late pregnancy may be at increased risk of late stillbirth. Fetal activity levels were lower when mothers slept on their backs, suggesting a potential link between maternal position and fetal wellbeing.
A new study suggests that enhancing breathing via the brain may limit respiratory muscle dysfunction in Duchenne muscular dystrophy patients. Researchers found that the brain compensates for respiratory muscle weakness by increasing diaphragm activation in mice with dystrophin deficiency.
Researchers found brain activity abnormalities persist even after seizure treatment, potentially underlying cognitive problems in children with absence epilepsy. This discovery suggests using EEG tests to diagnose and monitor attentional deficits in epilepsy patients.
Research in sheep model reveals babies born to overweight, obese mothers have less mature lungs, producing less surfactant and fewer cells that make it. This can lead to lung problems at birth and later during infancy and childhood.
Researchers discovered that physical activity offers health benefits against insulin resistance, a precursor to type 2 diabetes. The study found that exercise's ability to remove damaged cellular materials and enhance mitochondrial quality is more effective in preventing insulin resistance than previously thought.
Diabetes-induced changes in heartbeat are primarily regulated by the β1-adrenoceptor, suggesting that targeting this receptor could improve treatment outcomes for diabetics. The study provides novel insight into the pathological basis of heart rate dysregulation in type 2 diabetes.
Young veterans with combat-related PTSD have an increased 'fight or flight' response during mental stress, contributing to higher risks of high blood pressure and cardiovascular disease. Researchers found that these individuals had higher adrenaline levels and less control over their heart rate in response to blood pressure changes.
A study in rats found that resistance exercise improved motor coordination and memory impaired by MSG, with recognition memory improving in males and location memory in females. Researchers aim to understand the mechanism of this improvement.
New cells in retina found to directly affect biological clock by sending signals to brain region regulating daily rhythms. Disruption of circadian rhythms linked to health issues like gastrointestinal and cardiovascular disorders, depression, and cancer.
A study of 2,000 people found that women report higher stress levels than men for various life events, including death of a loved one, illness, and Brexit. This increased stress can lead to long-term physiological problems, such as ulcers or an increased risk of heart attack.
Researchers have identified a new way to distinguish between schizophrenia and depression using proteins in nerve cells. The method measures the level of hormone arginine-vasopressin (AVP) released in response to salt solution, which can indicate NMDA receptor signalling. This test may lead to earlier and more accurate diagnoses, as we...
A study on rat models found changes in brain activity and blood flow early in life, potentially linked to hypertension. The researchers suggest that these changes could be a cause of high blood pressure, paving the way for potential prevention strategies.
Research suggests that physical activity can have improved effects on muscle and blood vessel function in women in early postmenopause. The study found that high-intensity cycling training improved physiological parameters in this age group, providing a potential benefit against negative estrogen loss and aging effects.
A study published in Experimental Physiology found that body size, not sex, determines how people lose heat during exercise in warm conditions. The research involved 36 men and 24 women who underwent light and moderate exercise trials at controlled temperatures.
Research published in Experimental Physiology suggests that unsaturated fatty acids can reverse some of the effects of obesity on the immune system. Obesity was found to cause changes similar to those observed with aging, but supplementing the diet with unsaturated fatty acids reversed these effects.
Research suggests that supplementing mice with quercetin improves biomedical outcomes, providing anti-inflammatory and antioxidant effects. The study also found that quercetin-fed mice were more active than control groups, which could be beneficial for Duchenne Muscular Dystrophy patients.
Endurance training increases expression of genes repairing damaged DNA, potentially protecting the heart. Researchers hope this discovery leads to improved cardiovascular health and increased life expectancy.
A new study found that low thyroid hormone levels before birth impair the growth and development of the fetal pancreas, affecting insulin-secreting cells. This could lead to increased risk of pancreatic disorders and type 2 diabetes in later life.
A new study published in Experimental Physiology found that sprint interval training is a powerful stimulus to elicit cellular remodelling in both men and women. The research, conducted at McMaster University, showed that changes in gene expression over a short time-scale are similar between the sexes.
New research identifies physiological changes in the body that could explain why older mothers are more likely to experience complicated births. The study found that maternal age influences the structure of the uterus, leading to impaired muscle contraction properties, reduced sensitivity to oxytocin, and altered hormonal signals.
A new study found that well-trained women do not experience autonomic heat responses during exercise, despite common misconceptions. The research also revealed that humid heat reduces sweat effectiveness, leading to impaired performance.
Researchers used 3D electron microscopy to visualize collagen cables in skeletal muscle fibrosis, a roadblock to muscle recovery. Targeting these cables could provide treatments for conditions like muscular dystrophy, cerebral palsy, and age-related muscle loss, improving muscle function and reducing pain.
Research shows that a moderately reduced maternal food intake can accelerate the rate of aging in offspring's hearts. The study used baboons and found signs of impaired heart function at five years of life, equivalent to twenty human years.
New research challenges the use of ice baths after exercise, suggesting they may not reduce inflammation in muscles. The study found no significant benefit from cold water immersion on muscle inflammation compared to active recovery.
A study published in the Journal of Physiology found that fish oil pills can prevent and counter the negative effects of a high-fat diet. Mice fed fish oil had lower body fat and improved insulin resistance compared to those on a high-fat diet.
Researchers found that SIRT3's level of mRNA decreases, but its location remains the same after endurance exercise and fasting. This suggests that the activity of this enzyme may not be directly regulated by changes in its abundance within mitochondria in human skeletal muscle cells.
A recent study published in The Journal of Physiology found that stress during pregnancy and being born with low birth weight can lead to long-term health issues in mothers. The research, led by Jean Ni Cheong from the University of Melbourne, explored the effects of these factors on maternal health after pregnancy.
A recent study found that junk food diets can cause significant damage to the kidneys, similar to type 2 diabetes. The research used animal models and found that certain glucose transporters were present in higher numbers in rats with type 2 diabetes, but also increased after consuming high-fat or junk food diets.
Researchers found that serotonin shortens apnoeic events by interacting with the 5-HT3 receptor, which is highly expressed in healthy babies. This discovery may provide a new lead in understanding and treating SIDS and asphyxia., Serotonin's role in promoting inspiration and stopping apnea could be key to preventing these infant deaths.
Long-term exercise has been shown to improve muscle resistance and aerobic performance in mice with Spinal Muscular Atrophy. Swimming and running both had beneficial effects on motor neurons affected by the disease, suggesting specific types of exercise may limit neurodegeneration.
A study published in The Journal of Physiology found that neurons in the thalamus can be conditioned to respond to placebos in Parkinson's patients. When apomorphine was administered before a placebo, it increased thalamic neuronal activity and clinical improvement. The response lasted up to 24 hours.