Articles tagged with Drosophila
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A multidisciplinary team of scientists from UNIGE and MPIPKS has solved the mystery of how an organ changes its size depending on the size of the animal. They developed a mathematical equation that explains how cells know when to stop growing, using the example of the Paedocypris fish.
Scientists have identified a crucial mechanism for Rhodopsin production in fruit flies, which may lead to a better understanding of retinitis pigmentosa and vision loss. The study reveals that the EMC protein complex is essential for the proper folding and insertion of Xport-A, a key chaperone of Rhodopsin.
Researchers at the University of Tsukuba discovered a male-biased protein expression in primordial germ cells of fruit flies. The study used the Gal4-UAS system to induce gene expression and found that male cells had more protein synthesis occurring, with stronger GFP expression.
Researchers found that females who consumed less food for their entire lives lived longer but didn't reproduce as well as better-fed counterparts. However, those who switched to unlimited food after early life restriction started mating and reproducing more, producing three times more offspring than restricted diet flies.
A study involving Drosophila found that a constant and precisely regulated energy supply is essential for nerve development, particularly during the degradation of nerve connections. Malnutrition was shown to intensify defects in this process.
Researchers describe disassembly of Drosophila fly trachea during metamorphosis, revealing two-stage process involving cell shrinkage and death. The study highlights intricate involvement of physical mechanisms and biological signalling in regulating cellular decisions.
Researchers have identified a gene called Nup54 that plays a crucial role in regulating female reproductive behaviors in fruit flies. This discovery provides new insights into the molecular mechanisms underlying sexual conflict and its impact on evolution.
Scientists from the University of Tsukuba have developed a new technique to preserve Drosophila primordial germ cells, which can be used to produce new offspring. The cryopreserved PGCs were found to be effective after up to 400 days of long-term storage.
A new study published in Current Biology found that active genes do not form clusters and share resources during early fruit fly development. The researchers used high-resolution microscopy to visualize the physical position of active genes within the nucleus, observing that each gene has its own pool of transcriptional machinery.
Researchers at the University of Bonn identified a genetic program in fruit flies that controls neuron development and protection. The program, which involves the WNK gene, has similar functions in humans and may hold the key to understanding and treating neurodegenerative diseases.
Researchers at NICT unraveled a neural correlate of Pavlovian conditioning, discovering that alteration in information processing by feeding command neurons governs behavioral change. The experimental system made possible real-time observation of cell-cell connection for memory formation.
Researchers analyzed 99 vinegar fly species to understand how sex pheromones evolve and impact mating behaviors. The study found that male-specific compounds are abundant, while female-specific compounds are scarce, suggesting a crucial role for males in transmitting chemical signals.
Researchers developed transgenic strains of Drosophila suzukii that produce only males, using a common antibiotic as an off switch. The study found that releasing excess transgenic males into laboratory cage trials effectively suppressed female offspring.
Researchers found that fruit flies Drosophila melanogaster and Drosophila virilis use different mechanisms for dosage compensation. The primary components MSL2 and CLAMP are present in both species, but their binding sites on the X chromosome have evolved differently.
The study uses innovative imaging techniques to demonstrate the role of symmetric cell nucleus alignment in left-right asymmetric development. Collective nuclear behavior and proper nuclear positioning are found to be responsible for subsequent LR-asymmetric development of the midgut.
Researchers at the University of Minnesota have developed a method to cryopreserve fruit fly embryos, preserving their viability for up to generations. This breakthrough enables genetic research, disease modeling, and potential pest control applications, such as combating the invasive Drosophila suzukii.
Researchers discovered that fruit flies can fly up to 15 kilometers in a single journey, outpacing many migratory bird species. The study, led by Kate Leitch, used 'release and recapture' experiments with hundreds of thousands of common lab fruit flies.
Mehrnaz Afkhami, a University of Oklahoma doctoral biology student, received the graduate student poster award for her research on female behavioral response to male novel traits in fruit flies. Her study focuses on genetics and neurobiology aspects of this behavior.
Researchers discovered that HP1a is required to establish proper chromatin structure at multiple hierarchical levels during early embryonic development. The protein plays a central role in maintaining individual chromosome integrity and establishing the global structure of the genome.
Researchers discovered HP1a as an epigenetic regulator that establishes the global structure of the genome in early Drosophila embryos. The study used powerful genetics and 3D genome modeling to show that HP1a is required for proper chromatin organization at multiple hierarchical levels during embryonic development.
A team of researchers from the University of Tsukuba found that genes on the X chromosome in male fruit fly germ cells are not subject to dosage compensation, unlike other cells. The absence of this process may affect sex determination in Drosophila PGCs.
The invasive spotted wing drosophila prefers to lay its eggs in places that no other flies have visited, raising questions about how it detects virgin territory. This finding could inform the development of new pest-control techniques and mitigate significant crop losses.
Researchers discovered that the RPS-12 protein triggers triple-negative breast cancer and possibly other malignancies by activating an important signaling pathway. The protein's overproduction also leads to developmental abnormalities in fruit fly eyes.
Scientists studied gene expression patterns in Drosophila to understand the circadian rhythm, finding that individual flies have unique rhythms and genetic variations can affect behavior. The study also reveals genes that regulate circadian rhythms in humans, potentially impacting metabolic patterns and disease
Researchers at University of Exeter found that male Drosophila simulans flies with certain genital shapes produced more offspring. Surprisingly, despite rapid evolution of genital form, selection on this trait was relatively weak.
Researchers found that changes in a central gene node lead to the formation of larger eyes in some species, while different mechanisms explain smaller eyes in others. The study contributes to understanding of evolution of complex traits and could inform animal and plant breeding.
A new approach to studying DNA packaging allows scientists to study individual cells and uncover the underlying mechanisms of chromatin folding. The technique reveals that Drosophila fly cells have structured domains similar to those found in mammalian cells, but with more ordered structures.
A new study reveals that a natural enemy of the Asian fruit fly Drosphila suzukii is actually a complex of at least two cryptic species. Only one parasitoid, from one genetic group, has been found to be suitable as a biological control agent against the pest.
Researchers developed a new technique, CRISPR-LICHT, allowing for the analysis of hundreds of genes in human tissue using cerebral organoids. The method identified a specific mechanism controlling brain size and pinpointed microcephaly genes, shedding light on a genetic disorder.
Researchers from Russia and Switzerland successfully replicated the self-cleaning anti-reflective coating found in fruit flies' eyes, which can be applied in various fields such as textiles, medical implants, and contact lenses. The new nanocoating boasts antimicrobial, anti-reflective, and self-cleaning properties.
Researchers created a novel Drosophila-based disease model for Pitt-Hopkins syndrome (PTHS), which is caused by mutations in the TCF4 gene. The model reveals that certain substances can enhance learning and locomotor abilities in PTHS patients, suggesting potential therapeutic options.
A new dynamic mathematical model developed by researchers from the Universitat Autonoma de Barcelona has shown that it can accurately predict the probability of mortality and survival of small species under heat stress. The study's findings suggest that the current standard model subestimates species' vulnerability to climate warming a...
A mathematical model better accounts for temperature impacts from duration of exposure to improve predictions of heat mortality in natural Drosophila populations. The approach captures cumulative effects of thermal stress and is applicable to other small ectotherms.
Researchers at Cornell University developed a new method using thin mesh covering, called exclusion netting, to control spotted wing drosophila infestation in New York berry crops. The technique has shown significant benefits, including reduced pesticide use and lower costs, with minimal SWD incidence.
A new study found that flies from the Drosophila family have optimized their eye and nose sizes to adapt to different habitats, influencing behaviors such as courtship and habitat preferences.
Researchers found that the drug mifepristone blocks inflammation and reduces health decline in female fruit flies after mating, leading to longer lifespans. This effect is similar to what happens in women who take the drug, suggesting it may also extend human lifespan.
Researchers discovered that a changing mating signal in Drosophila mojavensis can initiate speciation. Females from subspecies with lost pheromones prefer courtship song over scent when choosing mates.
Researchers found that female flies were attracted to yeasts in foreign habitats, even if it meant reducing their offspring's survival chances. This openness could be a key factor in the emergence of new Drosophila species as they adapt to new environments.
Researchers at Clemson University have discovered that the genetic architecture of life span is context-dependent, with different genes and variants having varying effects on males and females and environmental temperatures. The study uses the Drosophila melanogaster model to provide valuable insights into human aging.
A study has uncovered a mechanism explaining how genetic mutations lead to nephrotic syndrome, a rare genetic kidney disorder. The researchers found that disruptions in the recycling of cell membranes cause abnormal kidney cell structure and function.
Scientists from Japan's University of Tsukuba discovered a regulatory pathway governing the first quiescence period in Drosophila germline cells. This break is crucial for pole cell migration and gamete development. The study confirmed that the two rest periods are essential for Drosophila germline development.
Researchers at Johannes Gutenberg University discovered a mechanism employed by fruit flies to broaden our understanding of visual perception. The team found that L3 neurons, sensitive to brightness, are active in low-light conditions and play a crucial role in detecting sudden changes in luminance.
Researchers found that changes in RNA splicing and protein Lark affect the production of messenger RNA, crucial for fighting gut infections. Genetic variants also modulate gene expression levels in response to infection.
Researchers studied geomagnetic imprinting in fruit flies using laboratory experiments. They found that the flies can learn and remember a magnetic field associated with a specific location and transmit this information to their offspring.
Researchers studied Drosophila and Chymomyza flies, revealing two possible explanations for arrhythmic behavior in high-latitude species. The study suggests that strong behavioral rhythms may be a disadvantage in polar regions, but certain characteristics could aid survival.
Researchers at Kyoto University discovered that fruit flies can thrive on various diets due to their flexible response to carbohydrates. In contrast, genetic cousins of the fruit fly are 'nutritional specialists' and can only grow on specific plants. The study sheds light on how organisms adapt to different nutritional environments.
Drosophila melanogaster forms a stable long-term memory for its body size and reach after hatching from the pupal case. The insects learn to estimate distance across gaps by linking visual information with their body size, retaining this knowledge for life.
Researchers have identified key proteins that determine tumor aggression in male and female flies, which could lead to specific treatments for men and women. The study found that removing a protein called Phf7 reduced the aggressiveness of tumors in males.
Researchers identified 239 genes with altered activity in long-living fruit fly strains, including those involved in metabolism. The mutation triggers a global alteration of metabolism, affecting carbohydrate, lipid, and nucleotide metabolism, as well as immune response genes.
A Cornell University study reveals that spotted-wing drosophila adults and larvae eat mushroom and apple mixtures, as well as bird manure, to survive before and after the growing season. The results may help curb pest populations by encouraging growers to limit access to certain non-fruit food sources.
A researcher at Children's National Hospital has received a $2 million NIH grant to study new approaches to treating kidney disease linked to the APOL1 risk allele. The team plans to use a Drosophila model to identify potential therapeutic targets and test compounds for effective treatment.
Researchers found that a repellent odor in a mixture specifically inhibits the perception of an attractive odor in vinegar flies, while geosmin activates only one specific glomerulus. This mechanism could help protect animals from contaminated food and potentially apply to humans as well.
Researchers found that Drosophila species invested primarily in vision or olfaction, but not both. The study used high-resolution microscopy and reconstructed primary sensory brain structures to analyze the trade-off between vision and olfaction.
Researchers at Children's National Hospital have received a $3 million NIH grant to investigate the mechanisms of APOL1 and HIV nephropathies in children. The study aims to understand how HIV-1 interacts with APOL1 risk variants in renal cells, triggering chronic kidney disease.
The University of Extremadura researchers have developed a methodology with new algorithms to analyse the location of centriole in a model cell. They discovered how the actin cytoskeleton influences polarised placement of centrioles in Drosophila and vertebrates.
Researchers discovered that wild African fruit flies prefer marula fruits over citrus and are seasonal specialists in their ancestral forests of Zimbabwe. This finding provides clues into how the flies first came to live among humans, attracted by the scent of marula.
Scientists have made fruit flies transparent using a new clearing method, allowing for high-resolution imaging of complex neural networks. This breakthrough enables the study of the connectome and behavior of Drosophila melanogaster, with potential applications in understanding neurodegenerative diseases.
A team of researchers has discovered a novel protein called Phaser that neatly arranges nucleosomes in the fruit fly genome. This finding sheds new light on how gene regulation is controlled, and could have important implications for our understanding of human disease.
Researchers found that fruit flies use a small, bright spot (the simulated sun) as a landmark to fly straight with respect to its position. The study also shows that these flies have compass neurons in their brains associated with this navigational behavior.
Researchers at Kumamoto University have identified a new mechanism linking cytoskeletal dynamics and Wnt5a signaling, essential for planar cell polarity formation. This control system regulates the morphology and orientation of cells in animal tissues, crucial for tissue morphogenesis.