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Overeating and starving both damage the liver: Cavefish provide new insight into fatty liver disease

Researchers have identified a gene responsible for the development of starvation-induced fatty liver in cavefish, which are able to protect their liver due to reduced fat accumulation. This genetic basis has implications for understanding and addressing liver conditions in humans, including Type 2 diabetes and obesity.

SourceStowers Institute for Medical Research·JournalLife Science Alliance·TypeExperimental study·DateMar 18, 2024

Pennington Biomedical researchers looking for new ways to improve life span and health during aging

Researchers found that a compound called BAM15 makes mitochondria less efficient at producing energy, extending life span and improving body composition in fruit flies. The study also showed reduced age-related decline in motor activity. Further studies are needed to confirm these findings in humans.

SourcePennington Biomedical Research Center·JournalAging Cell·TypeExperimental study·DateFeb 21, 2024

Repeated sexual failures cause social stress in fruit flies

Repeated sexual rejection in fruit flies causes social stress, leading to increased aggression and reduced resilience to starvation and toxic herbicide exposure. The response is mediated by the brain's neuropeptide F signaling system, which also plays a role in reward- and stress-responses in other organisms.

SourcePLOS·JournalPLOS Genetics·TypeExperimental study·DateJan 18, 2024
Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Franco-German research funding in the field of biology

Researchers from Johannes Gutenberg University Mainz and their French partners receive funding for two distinctive biology projects through the ANR-DFG program. The EVOMET project investigates plant metabolism, while the NeuroDevFunc project explores how fruit flies process visual motion generated by self-movement.

SourceJohannes Gutenberg Universitaet Mainz·DateJan 8, 2024

Stinky, bitter, and painful: A novel insect repellent attacks multiple sensory pathways

Researchers have identified a novel insect repellent, 2-methylthiazoline (2MT), which induces robust aversive responses through multiple sensory pathways in fruit flies. The compound stimulates both olfactory and nociceptive pathways, leading to avoidance behaviors and effective repulsion from fly pests.

SourceNational Institutes of Natural Sciences·JournalFrontiers in Molecular Neuroscience·TypeExperimental study·DateDec 22, 2023

Bugs that help bugs: How environmental microbes boost fruit fly reproduction

Researchers from Osaka University and University of Hawaii found that environmental microorganisms boost fruit fly reproduction by modifying hormone levels and increasing the production of germline stem cells. This discovery could lead to new avenues for improving reproductive health and fertility treatments.

SourceOsaka University·JournalCommunications Biology·TypeExperimental study·DateDec 21, 2023
Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Genomes from 25 museum specimens of Drosophila melanogaster (some more than 200 years old) reveal that small populations occupying northern Europe gave way to well-connected fly populations across the continent

Recent study on Drosophila melanogaster museum specimens shows that Northern European populations gave way to well-connected fly populations across the continent. The analysis also highlights genes that may have helped this species adapt to novel climates, viruses, and insecticides.

SourcePLOS·JournalPLOS Biology·DateOct 12, 2023

Fruit flies offer clues to how brains make reward-based decisions

Researchers studied fruit flies to understand how their brains assign value to rewards, finding that expectations play a crucial role in decision-making. By observing the flies' behavior, the team pinpointed the site in the brain where these value adjustments are made, enabling them to test a theoretical framework on neural circuits.

SourceHoward Hughes Medical Institute·JournalProceedings of the National Academy of Sciences·DateSep 22, 2023
Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Researchers identify neurons that guide flies upwind

A cluster of neurons in the fruit fly brain transforms memories about past rewards into actions, guiding the fly's navigation. The UpWiNs also send signals to dopaminergic neurons for higher-order learning, shedding light on parallel neural circuit mechanisms.

SourceHoward Hughes Medical Institute·JournaleLife·DateSep 19, 2023

Nutrients drive cellular reprogramming in the intestine

Researchers found that enteroendocrine cells in Drosophila intestinal epithelium undergo dedifferentiation into intestinal stem cells in response to nutritional changes, such as recovery from starvation. This process is vital for ISC expansion and subsequent intestinal growth following food intake.

SourceTohoku University·JournalDevelopmental Cell·DateSep 11, 2023

Fungi-eating plants and flies team up for reproduction

Researchers have discovered a novel nursery pollination system in which fungi-eating orchids and fruit flies engage in mutualistic symbiosis. The study found that the orchids offer their flowers to the flies in exchange for pollination, providing a breeding ground for the flies' larvae.

SourceKobe University·JournalEcology·TypeObservational study·DateAug 24, 2023

The protein protectors of fertility

Researchers from Osaka University have shed light on how certain proteins contribute to the formation of piRNAs, a type of RNA that protects the genome. Tejas plays a key role in recruiting Vas and Spn-E, facilitating nuage formation and piRNA processing.

SourceOsaka University·JournalJournal of Cell Biology·TypeExperimental study·DateAug 9, 2023
Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

How the microbiome drives the evolution of immune defenses

A study reveals that specific bacteria drive the evolution of antimicrobial peptides in Drosophila, providing insights into how host immune systems adapt to new ecological niches. The findings also suggest a new model for AMP-microbiome evolution.

SourceEcole Polytechnique Fédérale de Lausanne·JournalScience·DateJul 24, 2023

Fly toolkit created for investigating COVID-19 infection mechanisms

A new 'fly-to-bedside' resource has been developed to sort through the complexities of SARS-CoV-2 virus-host interactions. Researchers found that nine out of 10 non-structural proteins resulted in wing defects, providing a basis for understanding how viral proteins affect host proteins.

SourceUniversity of California - San Diego·JournalCell Reports·TypeExperimental study·DateJul 21, 2023
GoPro HERO13 Black

GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.

Fruit fly's complex symphony of vision

A unique microcircuit in fruit flies' visual system transforms a single type of neuronal input to compute direction selectivity, with no inhibitory neurons present. The discovery reveals a striking example of the multilayered mechanisms of inhibition and excitation in the brain.

SourceMax-Planck-Gesellschaft·JournalCurrent Biology·TypeExperimental study·DateMay 29, 2023
Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

Puppeteer fungus’ targeted takeover of zombie flies

A recent study by Carolyn Elya reveals the molecular mechanisms behind summiting behavior in infected fruit flies. The researchers discovered that hormonal axes mediate this behavior, and that fungal cells invade the fly's brains during summiting.

SourceHarvard University, Department of Organismic and Evolutionary Biology·JournaleLife·DateMay 19, 2023

How aggression-promoting brain peptide works in fruit flies

Researchers found that a specific neuropeptide affects two separate groups of neurons, promoting aggressive behavior in fruit flies. This discovery provides new insights into the complex mechanisms of neuronal communication using neuropeptides.

SourceSalk Institute·JournalJNeurosci·TypeExperimental study·DateMay 8, 2023

Air pollution impairs successful mating of flies

Ozone exposure destroys pheromones essential for fly mating, leading to abnormal behavior and reduced female attraction. The study's findings highlight the devastating impact of air pollution on insect populations.

SourceMax Planck Institute for Chemical Ecology·JournalNature Communications·TypeExperimental study·DateMar 14, 2023
SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

How fruit flies feast for pleasure as well as necessity

Researchers discovered that fruit flies have distinct hunger drives, one driven by need and the other by pleasure, which arise from unique neural mechanisms. The study found that hungry flies increase feeding event duration and total events, and identified specific brain regions activated by pleasurable food environments.

SourceeLife·JournaleLife·DateMar 7, 2023
Nikon Monarch 5 8x42 Binoculars

Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.

Mechanical forces in the nervous system play a corrective role

In a breakthrough study, researchers at Münster University revealed that mechanical tearing is the primary mechanism behind neurite pruning in sensory nerve cells of fruit flies. This process, which occurs during development, involves strong body contractions causing stress on fragile neurites, leading to their severance and removal.

SourceUniversity of Münster·JournalJournal of Cell Biology·TypeExperimental study·DateJan 25, 2023

Fruit flies grow brainy on a poor diet

Researchers at Kyoto University found that a poor, low-yeast diet causes fruit flies' larvae to grow dendrites in an unexpected way. The hyperarborization phenotype is triggered by a simultaneous deficiency in vitamins, metal ions, and cholesterol, which increases the production of Wingless signaling molecules from body wall muscle.

SourceKyoto University·JournaleLife·TypeExperimental study·DateJan 17, 2023

Fruit flies help researchers decode genetic link to Alzheimer’s disease

Researchers have discovered a possible cause of neurodegeneration in the early stages of Alzheimer's disease using fruit flies. The study found that an overabundance of the TOMM40 gene causes marked cell death in the retina, which corresponds to the level of protein produced by the gene.

SourceWalter and Eliza Hall Institute·JournalScientific Reports·TypeExperimental study·DateJan 9, 2023
GQ GMC-500Plus Geiger Counter

GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

Exercise curbs insulin production

Researchers discovered that physical activity suppresses insulin-producing cells in fruit flies, allowing for efficient energy replenishment. This finding has implications for human health, as reduced insulin activity is linked to healthy ageing and longevity.

SourceUniversity of Würzburg·JournalCurrent Biology·TypeExperimental study·DateJan 4, 2023

New study on the circadian clock of the fruit fly

Researchers discovered a point mutation in the fruit fly Drosophila melanogaster that leads to a temperature-dependent lengthening of circadian clock periods. The mutation affects the nuclear export signal of the PERIOD protein, resulting in its retention in the cell nucleus at higher temperatures.

SourceUniversity of Münster·JournalCurrent Biology·TypeExperimental study·DateDec 29, 2022

Cell quality control

In a groundbreaking study, researchers at Eötvös Loránd University have found that gland cells in Drosophila melanogaster can remove defective secretory particles as early as the secretion process begins. This discovery sheds new light on crinophagy, a previously understudied process crucial for maintaining cellular quality and function.

SourceEötvös Loránd University·JournalTraffic·DateDec 15, 2022
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

Invasive fruit fly may pose threat to forest ecosystems

The invasive spotted wing drosophila competes strongly with other fruit-eating species, causing massive ecological impacts on forests. The fly's presence alters fruit composition and visual cues, reducing consumption by birds and potentially disrupting seed-dispersal mutualisms.

SourcePensoft Publishers·JournalNeoBiota·DateNov 3, 2022
Sky-Watcher EQ6-R Pro Equatorial Mount

Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.

A new in a classic: a lipid required for vision identified in fruit flies

Researchers have identified an endocannabinoid, 2-linoleoyl glycerol (2-LG), responsible for activating TRP channels in photoreceptor cells. This discovery sheds light on the visual transduction process and may have implications for other sensory systems.

SourceNational Institutes of Natural Sciences·JournalScience Signaling·TypeExperimental study·DateOct 11, 2022

“Kipferl”: Guiding the defense against jumping genes

Researchers at IMBA found that Kipferl helps distribute Rhino to piRNA clusters, avoiding sequestration to Satellite arrays. This control mechanism ensures the effective silencing of jumping genes and maintains genome stability.

SourceIMBA- Institute of Molecular Biotechnology of the Austrian Academy of Sciences·JournaleLife·TypeExperimental study·DateOct 4, 2022

Towards a better understanding of depression

Researchers at Johannes Gutenberg University Mainz are studying the effects of natural substances used in traditional Asian medicine on depressive states in Drosophila flies. They found that certain substances can prevent the development of a depression-like state and even boost resilience to chronic stress.

SourceJohannes Gutenberg Universitaet Mainz·JournalCurrent Biology·DateSep 16, 2022

Protein ‘traffic jam’ in neurons linked to neurodegeneration

Neurobiologists identified mechanisms underlying atypical protein tangles that kill neurons in neurodegenerative disorders. Engineering Drosophila adults with human Tau revealed a 'traffic jam' effect, where reduced retromer activity accelerates neurodegeneration. Inhibiting the shortened form of Tau could stall neuron loss.

SourceEcole Polytechnique Fédérale de Lausanne·JournalNature Communications·DateAug 29, 2022
CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

CRISPR-based technology targets global crop pest

Researchers at the University of California San Diego have developed a precision-guided sterile insect technique (pgSIT) to control invasive fruit fly populations. The technology uses CRISPR editing to target key genes in female viability and male fertility, resulting in a fertility dead end for the species.

SourceUniversity of California - San Diego·JournalGEN Biotechnology·TypeExperimental study·DateAug 18, 2022

Why heat makes us sleepy

Researchers at Northwestern University found that a thermometer-like brain circuit promotes midday siestas on hot days. The study, which used fruit flies as a model organism, identified absolute heat receptors in fly heads, leading to increased midday sleep in flies and potentially humans.

SourceNorthwestern University·JournalCurrent Biology·DateAug 17, 2022

Buck Institute scientists uncover a new role for blood-brain barrier in neuron function and damage

Researchers at Buck Institute discover that blood-brain barrier cells influence neuron function and can cause problems rather than just being protective. This finding opens up new avenues for therapies targeting neurodegenerative diseases like Alzheimer's and Parkinson's.

SourceBuck Institute for Research on Aging·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateAug 15, 2022
Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

New study shows that ageing neutralizes sex differences in the brain

A new study found that ageing desexualizes the Drosophila brain transcriptome, causing both males and females to exhibit reduced gene expression differences. This effect is larger in males than females, indicating a weaker investment in sexual behaviors as they age.

SourceLinköping University·JournalProceedings of the Royal Society B Biological Sciences·DateAug 9, 2022

Can a parasitic wasp save your fruit crops?

Researchers at the University of Tsukuba have created a genetic toolkit to investigate the molecular mechanisms of a parasitic wasp, Asobara japonica. By analyzing its genome and using RNA interference, they identified key genes involved in venom production and found that suppressing these genes can lead to phenotypic changes.

SourceUniversity of Tsukuba·JournalDNA Research·DateJun 16, 2022

Genetic discovery could spell mosquitoes’ death knell

A UC Riverside genetic discovery found that mosquitoes lack the primary ecdysone transporter, allowing researchers to develop a mosquito-specific insecticide. This breakthrough could help control Zika, dengue, and other virus-carrying mosquitoes without harming beneficial insects.

SourceUniversity of California - Riverside·JournalProceedings of the National Academy of Sciences·DateJun 15, 2022
Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

Buck researchers uncover intriguing connection between diet, eye health and lifespan

Buck Institute researchers found that dietary restriction can extend lifespan in fruit flies due to changes in their circadian rhythms, particularly in the eye. The study suggests that the eye plays a role in regulating lifespan, which may have implications for human health and aging.

SourceBuck Institute for Research on Aging·JournalNature Communications·TypeExperimental study·DateJun 7, 2022

Fly researchers find another layer to the code of life

A new study has discovered that rare pieces of genetic code can serve as another layer of control in the genome, essential for fertility and evolutionary innovation. Researchers found that certain tissues are more tolerant of diverse codons, particularly the testes, which may play a critical role in fertility.

SourceDuke University·JournaleLife·TypeExperimental study·DateMay 19, 2022

NeuroMechFly: a digital twin of Drosophila

Researchers at EPFL's School of Life Sciences create a digital twin of Drosophila called NeuroMechFly, which uses biomechanical modeling and machine learning to simulate the fly's movements. The model is validated through experiments that demonstrate its accuracy in replicating real animal behaviors.

SourceEcole Polytechnique Fédérale de Lausanne·JournalNature Methods·DateMay 11, 2022
Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Decoding the molecular clock that controls neurogenesis in the visual center of Drosophila

In a study published in Nature Communications, researchers uncovered the molecular players involved and how timing is controlled for creating neural diversity. Single-cell RNA sequencing technology revealed a temporal patterning gene network in Drosophila medulla neuroblasts, including nine new transcription factors.

SourceCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign·JournalNature Communications·DateApr 5, 2022

The dark matter of the brain

Electrical synapses play a vital role in brain function and stability, influencing individual nerve cell activity. In Drosophila, researchers found electrical synapses occur in almost all brain areas, affecting visual processing and neuron stability.

SourceMax-Planck-Gesellschaft·JournalCurrent Biology·DateApr 5, 2022