A team at Duke University Medical Center has identified microsporidia as a sexually reproducing fungus that causes chronic diarrhea in AIDS patients and other host animals. The findings could help develop effective treatments against these common global pathogens.
A novel topical therapy, NB-002, has demonstrated a unique approach to healing nail fungus by penetrating skin pores and diffusing through the skin surrounding the entire nail plate. The lotion has shown robust antifungal activity against all organisms causing nail fungus, including Trichophyton rubrum and Candida albicans.
Researchers found that tadpoles help keep algae at the base of the food chain productive, but their absence leads to more sediment and less productive algae. The study demonstrates how the grazing activities of tadpoles help maintain a healthy stream ecosystem.
Researchers sequenced the fungus's genome and compared gene expression in different stages to identify key genes involved in killing frogs. They hope this study will help combat the deadly chytrid fungus, which affects over 43% of frog species.
A beetle uses a bacterium to protect its fungus from a competing mite, producing a novel antibiotic with potential for treating fungal diseases and cancer. The discovery highlights the importance of symbiotic relationships between insects and microbes in their survival.
Researchers found adult beetles store beneficial fungus and bacterium in specialized compartment to aid survival. This symbiotic relationship inhibits competitor fungus growth while promoting nutrition for developing larvae.
Researchers captured spore discharge mechanisms using ultra-high-speed cameras, revealing that fungi propel spores with explosive pressure loss, similar to inkjet printer nozzles. This breakthrough has implications for plant disease control, terrestrial ecology, and biomimetics.
Researchers aim to inform safety by design, safe disposal, and safe manufacturing handling for industrial-scale nanoparticles. The study tracks tagged nanoparticles in the environment to determine their bioaccumulation and transport through the food chain.
Researchers at Mayo Clinic and Virginia Bioinformatics Institute discover that eosinophils exert a strong immune response against the environmental fungus Alternaria alternata. The innate immune system of humans is capable of killing the fungus, which is linked to airway inflammation, chronic rhinosinusitis, and bronchial asthma.
A team of Yale undergraduates collected and analyzed 135 endophytes from plants in the Amazon rainforest, discovering dozens with potential bioactivity. The study's findings highlight the vast scientific potential of tropical areas and the importance of preserving these microorganisms.
A team of researchers discovered a novel fungus in the gut of Asian longhorned beetles that helps break down lignin, a protective barrier for plants. The fungus produces enzymes that enable the beetles to digest hard wood, leading to potential breakthroughs in pest control and biofuel production.
Researchers found that capsaicin slows microbial growth and protects the fruit from Fusarium fungus, allowing seeds to be dispersed. The production of capsaicin comes at a cost for chili plants, with thin seed coats being a consequence of prioritizing chemical protection.
A new study reveals that chili peppers' spiciness is a defense mechanism against microbial fungus that destroys seeds. The pungency acts as a unique defense, slowing down microbial growth and protecting the plant's progeny.
Scientists at the University of Warwick have found four types of fungi effective against varroa mites, which feed on honey bee circulatory fluid and transmit diseases. The researchers are exploring ways to deliver these killer fungi through various methods, including foot baths and powder sprays.
The USDA Forest Service has named the tree-killing fungus responsible for 'laurel wilt', causing devastating disease in redbay and other laurel species. Lead author Tom Harrington and co-author Stephen Fraedrich unveiled the name, Raffaelea lauricola, after publishing an article in Mycotaxon journal.
Rising temperatures may reduce microbial carbon dioxide production due to increased nitrogen levels in the soil, but human-induced CO2 changes could shift microbial populations with significant impacts on food chains. Microbial communities under glaciers and snowpacks are also threatened by warming temperatures.
A University of Missouri scientist discovered a mechanism in bread mold that 'silences' unmatched genes during meiosis, protecting the organism from genetic abnormalities. This process, known as MSUD, could have applications in pharmaceuticals and agriculture by precisely targeting unwanted genes.
Conservation efforts in Madagascar could avert catastrophic biodiversity loss with pro-active programs. The country harbors
The genome sequence of Podospora anserina shows the fungus has a large set of genes involved in breaking down complex carbon sources, including cellulose and lignin. This discovery may lead to novel regulatory mechanisms during growth and reproduction, with potential applications in biotechnology.
New Bt corn varieties have shown reduced levels of aflatoxin and lower rates of fungal infection, offering a potential solution to the global threat of this deadly toxin. The developments come as part of Monsanto's efforts to engineer better corn crops resistant to insect pests and environmental stressors.
Researchers explore alternative materials for digital signal processing, including fungi, bacteria, and DNA, which can enhance images and compress data without electrical currents. The field holds promise for improved algorithms and applications in disease detection and data storage.
Researchers found that disabling the ZFR1 gene reduces toxin production by 82% in Fusarium verticillioides on corn kernels. The study identified a specific sugar transporter, FST1, necessary for FB1 production, which acts as a molecular sensor for toxin creation.
Researchers discovered that ants have been farming fungus for approximately 50 million years, with four distinct agricultural systems emerging over time. These findings shed light on the evolution of agriculture and could lead to improved human agricultural and medical methods.
A new study reveals similarities between DNA that determine mating types in fungi and those that determine sex in plants and animals. This makes fungi an interesting model organism for studying the evolutionary development of sex chromosomes.
Researchers at Purdue University have discovered a gene that guards all grass species against a devastating fungus, which can destroy crops vital for human food supplies. The naturally occurring disease resistance has allowed grasses to thrive for 60 million years.
A team from Duke University Medical Center isolated sex-determining genes from an ancient fungus, Phycomyces blakesleeanus, which contains insights into the evolution of human sexual differentiation. The findings suggest that HMG-domain proteins may have marked the beginning of sex determination in both fungi and humans.
Researchers have discovered how life evolved from simple self-replicating molecules to complex organisms by studying a primitive fungus protein. The study shows how RNA progressed to share functions with proteins, a critical missing step in the evolution of life.
Researchers have successfully sequenced the complete genome of Malassezia globosa, a naturally occurring fungus responsible for dandruff and other skin conditions. The genetic make-up of M. globosa has expanded treatment targets from a few observational characteristics to over 4,000 molecular targets.
Researchers sequence Fusarium graminearum genome to understand its interaction with plants and develop resistance. The study aims to identify genes that enable the fungus to cause disease and produce toxins, which can be fatal to humans and livestock.
The Integrated Microbial Genomes (IMG) data management system has been upgraded to Version 2.3, featuring new microbial genomes from the National Center for Biotechnology Information (NCBI) Reference Sequence collection. The system now includes fungi, protists, and plant genomes, providing a broader comparative analysis platform.
Researchers at the University of Nottingham discovered that Aspergillus nidulans fungi can reproduce sexually without a partner. This 'DIY reproduction' allows individuals to produce new offspring by activating internal sexual machinery, bypassing traditional mating.
A new genetic analysis suggests that the frog-killing fungus, Batrachochytrium dendrobatidis, may be a greater threat to mountain yellow-legged frogs due to its ability to spread over long distances and persist in the environment through sexual reproduction. This could make it harder to save the frogs from extinction.
Researchers at Cold Spring Harbor Laboratory cloned the band gene, finding it's an allele of ras-1, which plays a crucial role in circadian rhythms. The study uses Neurospora crassa as a model organism, demonstrating how a dominant point mutation in ras-1 affects circadian growth cycles.
Researchers will identify Alternaria fungus antigens responsible for chronic sinusitis and its link to asthma. The goal is to develop new treatments and understand disease mechanisms.
Researchers have identified a bacterium that repels a deadly fungus causing worldwide amphibian deaths and extinctions. The discovery could lead to procedures for 'vaccinating' endangered populations.
Researchers at Albert Einstein College of Medicine found fungi can harness ionizing radiation to produce food and spur growth, recalculating Earth's energy balance. This discovery could provide a sustainable food source for long-duration space missions or planetary colonization.
Researchers will investigate the mechanisms of chronic rhinosinusitis (CRS), a debilitating airway disease affecting millions worldwide. They aim to identify specific fungal antigens contributing to the pathology and develop novel treatments.
A recent study by University of Cincinnati researchers suggests that early exposure to indoor fungal components can help build stronger immune systems and protect against future allergies. Infants exposed to high levels of fungal glucans were nearly three times less likely to wheeze compared to those with low levels.
Scientists at the University of Chicago have reclassified Prototaxites as a giant fungus, based on new evidence and chemical analysis. The fungus is believed to have stood up to 20 feet tall and thrived on land during the Silurian and Devonian periods.
MacroChem Corporation has completed patient enrollment in a Phase II efficacy study for EcoNail, a topical antifungal treatment for onychomycosis. The company aims to assess early signs of efficacy and collect 24-week interim data later this year.
Researchers found that a fungus relies on bacterial symbionts to break down plant nutrients and form spores, maintaining mutualism. The study highlights the critical role of symbiotic relationships in shaping biological processes.
A study by researchers at the University of Texas at Austin found that female rats can detect changes in males' germline cells due to exposure to vinclozolin, leading them to avoid mating with those males. This avoidance behavior is linked to an epigenetic change that affects the male's fertility.
Researchers at the University of Vermont have developed a 'whey-based fungal micro-factory' to combat the eastern hemlock tree's decline due to an exotic pest. The approach involves spraying a sweet whey solution with targeted fungus into infected forests, promoting self-replication and reducing pesticide use.
Researchers at the Weizmann Institute have designed a more powerful weapon to fight bacteria by combining key properties of antimicrobial peptides and lipopeptides. The new synthetic peptides exhibit both positive charge and soap-like ability to dissolve oils, targeting a range of bacterial and fungal infections.
Scientists identify AbNPS2 gene crucial to fungal spore cell wall integrity, impacting viability and host plant damage. Disruption of the gene leads to structural changes, decreased germination rates, and reduced survival under adverse conditions.
An international team of researchers has identified genes in Ustilago maydis that help the fungus live at its host plant's expense without killing it. The findings could lead to new ways to combat this fungus, which affects maize and other crops worldwide.
Researchers found that a gene for an anti-insect enzyme is up to 250 times more active in people with severe sinus inflammation. The enzyme's presence was linked to chronic sinusitis, which affects an estimated 32 million Americans.
The genome sequences of P. ramorum and P. sojae could lead to strategies to combat these destructive plant pathogens. Phytophthora species cause significant losses in various crops, including soybeans, oak trees, and cocoa beans, resulting in hundreds of billions of dollars in economic damage annually.
Researchers have developed a method to synthesize rasfonin, a cancer-killing compound derived from a fungus, in enough quantity to conduct proper biological tests. The new process produces 67 times more rasfonin than previous methods, offering a promising lead for the development of a potential anticancer drug.
Researchers found that symbiotic fungus reproduces sexually and disperse independently of ants, contradicting long-held theories. The fungi's ability to cross geographical boundaries allows them to intermingle genes with mainland populations.
Researchers aim to understand how prolonged space trips affect human immune systems by studying fruit flies on a Space Shuttle mission. The flies will be exposed to bacteria, fungi, and reduced gravity to determine if their weakened immune systems make them more susceptible to infection.
A study documents a sharp increase in Fusarium keratitis cases among contact lens wearers in Singapore, with nearly all patients wearing soft lenses and using ReNu brand cleaning solution. The outbreak has led to severe, sight-threatening lesions requiring hospitalization and corneal transplantation.
A new study by the University of Cincinnati found that infants exposed to specific airborne fungal spores have a higher risk of developing multiple allergies. The research team collected fungal spores from 144 infant homes and found that some fungi may cause allergic sensitization, while others inhibit allergy development.
A total of 34 cases of fungal keratitis were reported among soft contact lens wearers, with all cases caused by the fungus Fusarium. The average age of patients was 34.9 years, and most used ReNu brand contact lens solution.
A team of researchers has discovered a population of the painted frog, considered extinct since 1995, in Colombia's deserts. The finding offers hope that other species can survive the chytridiomycosis fungus and highlights the need for urgent conservation measures.
A new method has been developed to identify secondary metabolites in fungi, which are compounds that can have medicinal properties. The technique, known as genomic mining, allows researchers to pinpoint the genes responsible for producing these compounds, offering a promising tool for finding new medicines.
Researchers have identified genome sequences for three species of Aspergillus fungus, shedding light on their role in disease and potential for new treatments. The findings may help develop diagnostic tests and prevent allergies and diseases like pneumonia and sinusitis.
Researchers have discovered how plants use genes to fight off powdery mildew disease, a common fungal infection that affects over 9,000 species of plants. By disabling protective genes in Arabidopsis thaliana, the researchers found that a complex gene system can signal cell death and spare healthy cells from infection.
The lack of sexual reproduction in the asexual fungus Penicillium marneffei is limiting its ability to adapt to new environments, making it highly successful in its local area but stopping its spread to other areas. This inability to adapt may ultimately lead to extinction due to the importance of gene mixing for adaptation.
A recent study by the University of Manchester discovered that pillows can contain a substantial fungal load, with some samples having over 1 million fungal spores per pillow. The research highlights the potential for fungal contamination to exacerbate respiratory diseases like asthma and sinusitis in adults.