A study found that airborne fungal groups Cladosporium and Mycelia sterilia are more common in urban areas with high vehicular traffic, contributing to the region's high asthma incidence. The research suggests a link between environmental triggers and genetic susceptibility, shedding light on the complex factors driving the epidemic.
Researchers at Whitehead Institute found that combining an antifungal agent with Hsp90 inhibition is effective against multiple types of resistant fungal infections. The treatment could lead to development of novel therapies for patients with compromised immune systems, who suffer high mortality rates from these infections.
Researchers from DOE/JGI and FPL have deciphered the genetic mechanisms behind brown-rot fungi's ability to break down cellulose in wood. This breakthrough may lead to more efficient, cost-effective, and environmentally-friendly strategies for biofuels production.
Kansas State University is receiving a $1 million grant from the US Department of Agriculture to study the wheat blast fungus, a pathogen that has become a serious threat in Brazil. The researchers will sequence the fungus's genome and screen Kansas wheat varieties for resistance to the disease.
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Researchers discovered that pills used to treat fungal infections improve symptoms of asthma in those with an allergic reaction to fungi. Nearly 60% of patients taking the drug showed significant improvement.
A study by The University of Manchester found that patients with severe asthma and allergic sensitivity to certain fungi experience significant improvements in quality of life and lung function after taking an antifungal drug. However, symptoms often return after treatment is stopped.
Researchers at Harvard University discovered that many fungal species produce spores with aerodynamically optimized shapes, allowing them to minimize air resistance and maximize travel distance. In contrast, spores transported by animals lack these drag-minimizing features.
Biologists have discovered a sexual cycle in the deadly fungus Aspergillus fumigatus, revealing its ability to adapt to new environments and evade antifungal drugs. This breakthrough could lead to new treatments for patients infected with the fungus, which causes severe asthma and immune deficiency-related deaths.
Researchers found that global warming may not be the primary cause of widespread amphibian declines, contradicting previous widely-held views. The study suggests alternative factors, such as a fungal infection and pesticide use, may be driving these extinctions.
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A unique fungus, Gliocladium roseum, has been discovered to produce diesel compounds from cellulose, offering a promising alternative to traditional biofuels. The fungus can make myco-diesel directly from cellulose, skipping a step in the production process.
A team at Montana State University has discovered a fungus that produces diesel fuel, which could offer an alternative to fossil fuels. The fungus, called Gliocladium roseum, can grow in cellulose and produce medium-chain hydrocarbons.
A team at Duke University Medical Center has identified microsporidia as a sexually reproducing fungus that causes chronic diarrhea in AIDS patients and other host animals. The findings could help develop effective treatments against these common global pathogens.
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A novel topical therapy, NB-002, has demonstrated a unique approach to healing nail fungus by penetrating skin pores and diffusing through the skin surrounding the entire nail plate. The lotion has shown robust antifungal activity against all organisms causing nail fungus, including Trichophyton rubrum and Candida albicans.
Researchers found that tadpoles help keep algae at the base of the food chain productive, but their absence leads to more sediment and less productive algae. The study demonstrates how the grazing activities of tadpoles help maintain a healthy stream ecosystem.
Researchers sequenced the fungus's genome and compared gene expression in different stages to identify key genes involved in killing frogs. They hope this study will help combat the deadly chytrid fungus, which affects over 43% of frog species.
Researchers found adult beetles store beneficial fungus and bacterium in specialized compartment to aid survival. This symbiotic relationship inhibits competitor fungus growth while promoting nutrition for developing larvae.
A beetle uses a bacterium to protect its fungus from a competing mite, producing a novel antibiotic with potential for treating fungal diseases and cancer. The discovery highlights the importance of symbiotic relationships between insects and microbes in their survival.
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Researchers captured spore discharge mechanisms using ultra-high-speed cameras, revealing that fungi propel spores with explosive pressure loss, similar to inkjet printer nozzles. This breakthrough has implications for plant disease control, terrestrial ecology, and biomimetics.
Researchers aim to inform safety by design, safe disposal, and safe manufacturing handling for industrial-scale nanoparticles. The study tracks tagged nanoparticles in the environment to determine their bioaccumulation and transport through the food chain.
Researchers at Mayo Clinic and Virginia Bioinformatics Institute discover that eosinophils exert a strong immune response against the environmental fungus Alternaria alternata. The innate immune system of humans is capable of killing the fungus, which is linked to airway inflammation, chronic rhinosinusitis, and bronchial asthma.
A team of Yale undergraduates collected and analyzed 135 endophytes from plants in the Amazon rainforest, discovering dozens with potential bioactivity. The study's findings highlight the vast scientific potential of tropical areas and the importance of preserving these microorganisms.
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A team of researchers discovered a novel fungus in the gut of Asian longhorned beetles that helps break down lignin, a protective barrier for plants. The fungus produces enzymes that enable the beetles to digest hard wood, leading to potential breakthroughs in pest control and biofuel production.
A new study reveals that chili peppers' spiciness is a defense mechanism against microbial fungus that destroys seeds. The pungency acts as a unique defense, slowing down microbial growth and protecting the plant's progeny.
Researchers found that capsaicin slows microbial growth and protects the fruit from Fusarium fungus, allowing seeds to be dispersed. The production of capsaicin comes at a cost for chili plants, with thin seed coats being a consequence of prioritizing chemical protection.
Scientists at the University of Warwick have found four types of fungi effective against varroa mites, which feed on honey bee circulatory fluid and transmit diseases. The researchers are exploring ways to deliver these killer fungi through various methods, including foot baths and powder sprays.
The USDA Forest Service has named the tree-killing fungus responsible for 'laurel wilt', causing devastating disease in redbay and other laurel species. Lead author Tom Harrington and co-author Stephen Fraedrich unveiled the name, Raffaelea lauricola, after publishing an article in Mycotaxon journal.
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Rising temperatures may reduce microbial carbon dioxide production due to increased nitrogen levels in the soil, but human-induced CO2 changes could shift microbial populations with significant impacts on food chains. Microbial communities under glaciers and snowpacks are also threatened by warming temperatures.
A University of Missouri scientist discovered a mechanism in bread mold that 'silences' unmatched genes during meiosis, protecting the organism from genetic abnormalities. This process, known as MSUD, could have applications in pharmaceuticals and agriculture by precisely targeting unwanted genes.
The genome sequence of Podospora anserina shows the fungus has a large set of genes involved in breaking down complex carbon sources, including cellulose and lignin. This discovery may lead to novel regulatory mechanisms during growth and reproduction, with potential applications in biotechnology.
Conservation efforts in Madagascar could avert catastrophic biodiversity loss with pro-active programs. The country harbors
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New Bt corn varieties have shown reduced levels of aflatoxin and lower rates of fungal infection, offering a potential solution to the global threat of this deadly toxin. The developments come as part of Monsanto's efforts to engineer better corn crops resistant to insect pests and environmental stressors.
Researchers explore alternative materials for digital signal processing, including fungi, bacteria, and DNA, which can enhance images and compress data without electrical currents. The field holds promise for improved algorithms and applications in disease detection and data storage.
Researchers found that disabling the ZFR1 gene reduces toxin production by 82% in Fusarium verticillioides on corn kernels. The study identified a specific sugar transporter, FST1, necessary for FB1 production, which acts as a molecular sensor for toxin creation.
Researchers discovered that ants have been farming fungus for approximately 50 million years, with four distinct agricultural systems emerging over time. These findings shed light on the evolution of agriculture and could lead to improved human agricultural and medical methods.
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A new study reveals similarities between DNA that determine mating types in fungi and those that determine sex in plants and animals. This makes fungi an interesting model organism for studying the evolutionary development of sex chromosomes.
Researchers at Purdue University have discovered a gene that guards all grass species against a devastating fungus, which can destroy crops vital for human food supplies. The naturally occurring disease resistance has allowed grasses to thrive for 60 million years.
A team from Duke University Medical Center isolated sex-determining genes from an ancient fungus, Phycomyces blakesleeanus, which contains insights into the evolution of human sexual differentiation. The findings suggest that HMG-domain proteins may have marked the beginning of sex determination in both fungi and humans.
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Researchers have discovered how life evolved from simple self-replicating molecules to complex organisms by studying a primitive fungus protein. The study shows how RNA progressed to share functions with proteins, a critical missing step in the evolution of life.
Researchers have successfully sequenced the complete genome of Malassezia globosa, a naturally occurring fungus responsible for dandruff and other skin conditions. The genetic make-up of M. globosa has expanded treatment targets from a few observational characteristics to over 4,000 molecular targets.
Researchers sequence Fusarium graminearum genome to understand its interaction with plants and develop resistance. The study aims to identify genes that enable the fungus to cause disease and produce toxins, which can be fatal to humans and livestock.
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The Integrated Microbial Genomes (IMG) data management system has been upgraded to Version 2.3, featuring new microbial genomes from the National Center for Biotechnology Information (NCBI) Reference Sequence collection. The system now includes fungi, protists, and plant genomes, providing a broader comparative analysis platform.
Researchers at the University of Nottingham discovered that Aspergillus nidulans fungi can reproduce sexually without a partner. This 'DIY reproduction' allows individuals to produce new offspring by activating internal sexual machinery, bypassing traditional mating.
A new genetic analysis suggests that the frog-killing fungus, Batrachochytrium dendrobatidis, may be a greater threat to mountain yellow-legged frogs due to its ability to spread over long distances and persist in the environment through sexual reproduction. This could make it harder to save the frogs from extinction.
Researchers at Cold Spring Harbor Laboratory cloned the band gene, finding it's an allele of ras-1, which plays a crucial role in circadian rhythms. The study uses Neurospora crassa as a model organism, demonstrating how a dominant point mutation in ras-1 affects circadian growth cycles.
Researchers will identify Alternaria fungus antigens responsible for chronic sinusitis and its link to asthma. The goal is to develop new treatments and understand disease mechanisms.
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Researchers have identified a bacterium that repels a deadly fungus causing worldwide amphibian deaths and extinctions. The discovery could lead to procedures for 'vaccinating' endangered populations.
Researchers at Albert Einstein College of Medicine found fungi can harness ionizing radiation to produce food and spur growth, recalculating Earth's energy balance. This discovery could provide a sustainable food source for long-duration space missions or planetary colonization.
Researchers will investigate the mechanisms of chronic rhinosinusitis (CRS), a debilitating airway disease affecting millions worldwide. They aim to identify specific fungal antigens contributing to the pathology and develop novel treatments.
A recent study by University of Cincinnati researchers suggests that early exposure to indoor fungal components can help build stronger immune systems and protect against future allergies. Infants exposed to high levels of fungal glucans were nearly three times less likely to wheeze compared to those with low levels.
Scientists at the University of Chicago have reclassified Prototaxites as a giant fungus, based on new evidence and chemical analysis. The fungus is believed to have stood up to 20 feet tall and thrived on land during the Silurian and Devonian periods.
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MacroChem Corporation has completed patient enrollment in a Phase II efficacy study for EcoNail, a topical antifungal treatment for onychomycosis. The company aims to assess early signs of efficacy and collect 24-week interim data later this year.
Researchers found that a fungus relies on bacterial symbionts to break down plant nutrients and form spores, maintaining mutualism. The study highlights the critical role of symbiotic relationships in shaping biological processes.
A study by researchers at the University of Texas at Austin found that female rats can detect changes in males' germline cells due to exposure to vinclozolin, leading them to avoid mating with those males. This avoidance behavior is linked to an epigenetic change that affects the male's fertility.
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Researchers at the University of Vermont have developed a 'whey-based fungal micro-factory' to combat the eastern hemlock tree's decline due to an exotic pest. The approach involves spraying a sweet whey solution with targeted fungus into infected forests, promoting self-replication and reducing pesticide use.
Researchers at the Weizmann Institute have designed a more powerful weapon to fight bacteria by combining key properties of antimicrobial peptides and lipopeptides. The new synthetic peptides exhibit both positive charge and soap-like ability to dissolve oils, targeting a range of bacterial and fungal infections.
Scientists identify AbNPS2 gene crucial to fungal spore cell wall integrity, impacting viability and host plant damage. Disruption of the gene leads to structural changes, decreased germination rates, and reduced survival under adverse conditions.
An international team of researchers has identified genes in Ustilago maydis that help the fungus live at its host plant's expense without killing it. The findings could lead to new ways to combat this fungus, which affects maize and other crops worldwide.
Researchers found that a gene for an anti-insect enzyme is up to 250 times more active in people with severe sinus inflammation. The enzyme's presence was linked to chronic sinusitis, which affects an estimated 32 million Americans.
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The genome sequences of P. ramorum and P. sojae could lead to strategies to combat these destructive plant pathogens. Phytophthora species cause significant losses in various crops, including soybeans, oak trees, and cocoa beans, resulting in hundreds of billions of dollars in economic damage annually.
Researchers have developed a method to synthesize rasfonin, a cancer-killing compound derived from a fungus, in enough quantity to conduct proper biological tests. The new process produces 67 times more rasfonin than previous methods, offering a promising lead for the development of a potential anticancer drug.