Indiana University-Purdue University Indianapolis researchers have developed a new methodology to improve identification of breast cancer tissue by pathology laboratories. Their work, recognized internationally, has been selected as the best scientific paper in the
Researchers found that smokers who try to suppress their thoughts of smoking tend to smoke more than usual when they stop, a phenomenon known as behavioral rebound. This suggests that techniques like thought suppression may not be effective in quitting smoking and could even lead to increased consumption.
Chronic health conditions are widespread among stem cell transplant survivors, with 66% reporting at least one condition and 35% experiencing three or more. Chronic graft-versus-host disease also increases the risk of severe or life-threatening conditions.
Thin films of europium titanate become both ferroelectric and ferromagnetic when stretched across a substrate, displaying electrical properties 1,000 times better than existing materials. This breakthrough could lead to the development of next-generation memory storage, magnetic sensors, and highly tunable microwave devices.
A new study suggests that a massive reduction in green pastures and the spread of forests may have been the primary cause of the decline of mammals like the woolly mammoth. The research found that climate change and habitat changes made grazing difficult for large mammals, leading to their extinction.
A study published in Catheterization and Cardiovascular Interventions confirms the safety and effectiveness of drug-eluting stents (DES) for long-term use. The use of DES reduces the occurrence of myocardial infarction, target vessel revascularization, and mortality compared to bare-metal stents.
A new study by North Carolina State University researchers has found a way to implement wireless monitoring technology using HVAC ducts. This technology could lead to significant savings in climate control and health applications by avoiding the need for extensive wiring.
Researchers are testing a new drug therapy, MGAWN1, to treat individuals with West Nile fever or suspected central nervous system infection. The treatment has the potential to neutralize the virus and reduce complications associated with the disease.
Researchers have identified two effective treatments for neuroblastoma in mice using existing medications DECA-14 and rapamycin. The study used cancer stem cells directly isolated from children's tumors to test the drugs' efficacy without harming healthy cells.
Researchers developed a titanium coating with protein 'flower bouquet' nanoclusters that strengthened implant attachment by 50% compared to standard coatings. The clusters improved bone growth around the implant, enhancing cell adhesion signals and promoting better integration of biomaterial implants into bone.
Researchers found a unique genome structure formed by protein complexes that regulate cell-type-specific genes, leading to developmental diseases. Deficiencies in these complexes can cause syndromes like Opitz-Kaveggia syndrome and schizophrenia.
A new HIV drug candidate called PIE12-trimer has been developed by a University of Utah biochemist, which prevents the virus from attacking human cells. The compound is designed with a unique resistance capacitor that makes it effective against emerging drug-resistant viruses.
Researchers at Mayo Clinic found that healthy young people who gained as little as 9 pounds of fat in their abdomens developed endothelial cell dysfunction, impairing blood flow regulation. In contrast, those who gained weight evenly throughout their bodies showed less affected blood flow regulation.
The use of advanced web-based medical technologies is increasing the role of consumers in their own healthcare, providing access to reliable drug information and decision support tools. These innovative solutions, such as Healthline DrugSearch, enable users to compare treatments and understand interactions with multiple prescriptions.
Researchers have discovered a method to improve the performance of organic solar cells by modifying an interface between an organic polymer and an inorganic oxide layer. This breakthrough could significantly enhance the industry's prospects for producing efficient and environmentally friendly electricity.
A pioneering new study led by University of Leicester researchers shows that training Health Visitors to assess and support mothers after childbirth can significantly reduce the development of depression over the following year. Intervention women were 30% less likely to develop depression compared to control women receiving usual care.
A new US survey reveals that many Americans underestimate the impact of switching to efficient technologies on saving energy. The study found that turning off lights is often cited as the best approach, despite its minimal effect, while more significant changes like buying efficient cars and appliances are underutilized.
A new study published in the journal Addictive Behaviors found that aggressive and hyperactive boys with low parental monitoring are more likely to become heavy drug users as teens. However, if these boys are highly monitored and befriend good peers as children, they can avoid substance abuse.
Research reveals that carnivorous plants like sundews prioritize pollination over insect safety, with taller flowers attracting more visitors. A study of two sundew species found that longer stems increased flower visits by ten times compared to shorter ones.
A work group led by a Kaiser Permanente researcher developed and adopted 17 national measures to assess HIV care quality, including screening, prevention, and antiretroviral therapy. These measures have been endorsed by several organizations and are being pilot-tested to improve patient outcomes.
A recent study by Donald Light reveals that the pharmaceutical industry prioritizes profits over patient safety, with many drugs offering little new benefit and significant risks. The study highlights flaws in the regulatory process, including incomplete clinical trials and biased testing, which can lead to serious harm to patients.
Researchers found that gene variants associated with type-1 diabetes and rheumatoid arthritis confer previously unknown benefits to their human carriers. This suggests that the human race may be evolving towards greater susceptibility to complex diseases.
NASA satellites have been tracking Tropical Depression 5's remnants, which are bringing heavy rainfall to southeastern Louisiana and coastal Mississippi. The National Weather Service has issued a Flash Flood Watch and Coastal Flood Advisory due to the expected heavy rainfall and coastal flooding.
The NYU Urothelial Biology Team has received a five-year, $8.2 million grant from the NIDDK to investigate bladder biology and diseases such as UTI. The team aims to understand how disease-causing bacteria interact with host urothelial cells, which is crucial for developing novel treatments for recurrent UTI and other urologic diseases.
A joint project of UCSF and KEMRI has received a 5-year grant to expand its care and support for people affected by HIV/AIDS in Kenya. The grant will allow the project to serve at least 80% of HIV patients needing care within its service areas.
A study found that long-term cumulative mortality was highest among patients with system delays of 121-180 minutes, increasing by 28.1% and 30.8% respectively. System delay was independently associated with mortality in multivariate analysis.
Researchers discovered that the Prox1 gene plays a crucial role in developing and maintaining cells vital for making new memories throughout life. The study revealed a novel feedback mechanism regulating differentiation of adult neural stem cells.
A team of researchers at Tel Aviv University has developed genetically mutated mice to study Vanishing White Matter disease, which destroys brain myelin. The new tool allows for the first time to follow the exact process of myelin destruction, providing valuable information about the molecular mechanisms of the disease.
A Brigham Young University study shows that voters are less objective in evaluating their governor's economic performance if the White House is controlled by the opposing political party. The analysis found that voters overestimate the policy success of the level of government their preferred party controls, leading to rosier assessmen...
Researchers are investigating the effects of radiation on human bone strength to improve treatment for cancer patients with bone metastases. The study aims to establish the mechanical strength of bone before and after stereotactic radiosurgery, which has been shown to cause high fracture rates in post-treatment patients.
A new statistical method confirms that mitochondrial Eve, the mother of all humans, lived around 200,000 years ago. The study compared 10 human genetic models and found that they produced similar estimates, suggesting that refining assumptions beyond a certain point is not crucial in capturing the big picture.
Researchers found that long-lived aspen clones experience reduced sexual performance and increased risk of extinction with age. The study, published in PLOS Biology, used molecular clock estimates to determine the age of individual clones and measured male fertility.
A predictive model using factors like age, blood pressure, and heart rate accurately predicted the development of critical illness in patients who received out-of-hospital emergency care. The study found that hospitals varying widely in quality of critical care could improve outcomes for critically ill patients by concentrating care at...
Astronomers detected X-ray eclipses from a fast pulsar, shedding light on compressed matter and testing relativity. The system's unique properties revealed the size and mass of the companion star with unprecedented accuracy.
A new report from Johns Hopkins Bloomberg School of Public Health finds that trauma center care is cost-effective for patients with severe injuries and those younger than 55. The study estimates that trauma center care saves lives at a lower cost per life-year gained compared to non-trauma center care.
A study by University of Cincinnati professor David Maume found that men who worked late shifts believed it negatively impacted their marriages, whereas most women saw rotating work schedules as a strain on their marriages. Women reported greater difficulty in caring for and nurturing family members due to their schedules.
Research conducted by the USDA found that low levels of folate are associated with symptoms of dementia and poor brain function, as well as depression in women. The study also identified a protein called holoTC as a potential key to detecting cognitive decline earlier.
A researcher at Michigan State University is studying the role of the innate immune system in protecting against lung cancer. Alison Bauer's work may lead to new approaches to prevent, identify and treat lung cancer.
A study by Monash University researchers reveals that bees use a 'hot' drink to warm up on cold days and a 'cool' drink in warmer weather. The bees preferred feeding from artificial flowers with warmer nectar, which helped them maintain an optimal body temperature for flight.
A new study from North Carolina State University found large discrepancies in ADHD diagnosis rates based on small differences in children's birth dates. Children born shortly after the kindergarten eligibility cutoff date were 25% less likely to be diagnosed with ADHD, suggesting that younger children may be mistakenly diagnosed.
A recent study by University of Alberta research fellow Amy Speed-Andrews found that Iyengar yoga improved physical and mental health in breast cancer survivors. The 10-week program showed significant reductions in stress, anxiety, and depression, with participants experiencing improvements in quality of life and overall well-being.
A recent study by the University of Michigan Health System found that black patients are prescribed fewer pain medications than whites, while women receive weaker doses. The research highlights racial and gender gaps in pain care and suggests changes are needed to address these disparities starting in primary care.
Children as young as 3-4 years old use statistical information to infer the preferences of others. In experiments, they were more likely to give a toy to someone who had selected it from a container with a low proportion of that toy type. This ability is crucial for learning about others' desires and preferences.
Researchers estimate that harnessing 10% of Australia's near-shore wave energy could generate enough electricity to meet half of the country's present-day consumption. This could contribute significantly to Australia's goal of producing 45,000 gigawatt-hours/year of additional renewable energy by 2020.
Princeton researchers uncover ancient sponge-like creatures with fossilized shells dating to 650 million years ago, rewriting the timeline of life on Earth. The discovery provides direct evidence that animal life existed before and survived a severe 'snowball Earth' event.
Scientists have discovered an accomplice in breast cancer – a master control switch with the power to set off a cascade of reactions orchestrated by a cancer-causing gene named Wnt1. The executive molecule MTA1 is reported to trigger cancer-causing signals from Wnt1 in human breast cancer cells, leading to tumors.
Physicists have discovered evidence of natural nuclear accelerators at work in the Milky Way galaxy, based on an analysis of data from the world's largest cosmic ray detector. The researchers found that stellar explosions in our own galaxy can accelerate both protons and nuclei, explaining the origin of ultra-high-energy nuclei.
A Michigan State University economist found that nearly 20% of the 4.5 million children currently diagnosed with ADHD may have been misdiagnosed due to their age relative to classmates. The study suggests that teachers' perceptions of young children's behavior can lead to incorrect diagnoses and unnecessary medication.
Research published in the Journal of Physiology found that astronaut muscles deteriorate to that of an 80-year-old after just 180 days in space. The study highlights the need for effective exercise countermeasures to protect muscle and bone on long-duration space missions.
The discovery of primitive sponge-like creatures living in ocean reefs around 650 million years ago pushes back the clock on when animal life appeared on Earth. The fossils, found in South Australia, represent the earliest evidence of animal body forms in the current fossil record.
Researchers at Boston University and VA have discovered a new disease, CTEM, that mimics ALS in athletes with repeated head trauma. The disease is characterized by abnormal tau protein deposits and TDP-43 pathology, which are also found in sporadic ALS cases.
Scientists at Tohoku University have recorded data at a world-record density of 4 trillion bits per square inch using the ferroelectric data storage method. This density is eight times that of today's most advanced magnetic hard-disk drives.
Researchers at Iowa State University have discovered a special set of sugars that helps certain pathogens evade the body's natural defenses and vaccines. The finding may lead to new research for developing vaccines or cures for diseases like tuberculosis.
Researchers discover small RNAs regulate genes involved in chronic pain, offering a new avenue for developing drugs to treat debilitating conditions like arthritis and back pain. Small RNAs may serve as possible drug targets to restore normal pain thresholds.
A large, randomized controlled trial found that a surgically implanted antibiotic sponge did not reduce the rate of sternal wound infections after cardiac surgery. The study contradicts previous results and suggests ethnic and regional differences may have contributed to the differing outcomes.
A recent study conducted by researchers from the University of Chicago found that marriage and committed relationships significantly lower cortisol levels and increase testosterone production in response to psychological stress. The findings suggest that long-term monogamous relationships can have a dampening effect on stress hormones.
Researchers found that emodin from Chinese herbs can lower blood glucose and serum insulin levels in mice with diet-induced obesity. The herb's active compound effectively limits the effect of glucocorticoids, which contribute to insulin resistance.
Researchers have created the world's first frozen repository for Hawaiian coral, banking cells to preserve species diversity and potentially restore populations. The frozen material can be thawed decades or even centuries later to revive coral reefs threatened by climate change, pollution, and human impact.
Researchers estimate ITN coverage in 44 African countries between 2000 and 2008, with some countries scaling up coverage to over 60%. However, others, such as Nigeria, remain undercovered. The study suggests increased development assistance for health is related to improved ITN coverage.
A collaborative study examines a family with two rare genetic deletions, CNTNAP5 and DOCK4, which are associated with autism and reading difficulties. The research suggests that the CNTNAP5 deletion is linked to autism, while the DOCK4 deletion is co-segregated with reading difficulties.