Scientists have identified a crucial role for sulfonation in HIV replication, finding that inhibiting this pathway can compromise viral gene expression and render host cells resistant to infection. This discovery provides a promising new target for HIV/AIDS therapy.
Researchers at the University of Pittsburgh discovered that exposure to EPA-approved levels of arsenic in drinking water can lead to cardiovascular disease by closing pores in liver blood vessels. The study found that mice exposed to arsenic had impaired sinusoidal cell functions, leading to a loss of nutrient exchange and waste removal.
Researchers found that consumption of red meat introduces a non-human glycan molecule, promoting chronic inflammation and tumor growth. Anti-inflammatory treatment reduced tumor size in mice, suggesting a potential link between red meat and cancer risk.
A new web site designed for young girls aged 8-11 aims to prevent smoking through online patient education and interactive features. The site, No Smoking Room.Org, engages users with multimedia content and allows them to test their knowledge and share it with others.
A recent study published by the American Society for Radiation Oncology found that males diagnosed with non-small cell lung cancer have a higher mortality rate than females. The research also revealed that gender is a significant prognostic factor in lung cancer patients' overall survival rates.
A Japanese research team discovered that the wasabi receptor can sense and respond to ammonia, a base known to cause pain. The study, published in Journal of Clinical Investigation, reveals the molecular entity responsible for this phenomenon, providing insight into the mechanisms behind sushi-induced discomfort.
The new online community aims to accelerate creation of critically needed nanotechnology standards, including reference materials and tests. The initiative will utilize Web 2.0-style social networking technologies to facilitate information sharing and deliberation among experts.
The new solar system orbits a dusty young star named HR8799, with three planets roughly 10 times the mass of Jupiter. The discovery allows scientists to study planets as individuals, providing insights into their atmospheres and composition.
A team of Iowa State physicists, including Soeren Prell, are part of an international research team testing the Kobayashi-Maskawa theory, which explains the difference between matter and antimatter. The BaBar experiment has confirmed the theory's predictions and provided insights into the universe's origins.
A gene essential for organ growth also regulates female but not male embryo sexual development, supporting a controversial hypothesis about mammalian sexual development. Researchers found that beta-catenin acts as an internal regulator of the pathway, which includes Wnt4 and R-spondin1 genes, leading to the formation of ovaries.
A recent study published in European Urology found a significant relationship between prostate inflammation and lower urinary tract symptoms (LUTS) in men. The study, which analyzed data from the REDUCE trial, revealed that chronic inflammation was associated with higher IPSS scores and a greater degree of LUTS.
A study in Mexico City found that asthmatic children are more likely to experience worsening respiratory symptoms when living near high-traffic areas. The study, led by Dr Isabelle Romieu, suggests that diesel particles have a significant impact on respiratory health.
Stickleback fish follow a consensus decision-making process to choose their leader, prioritizing size, fatness, and health. As group size increases, accuracy improves, but occasional errors occur due to submission to peers and cascades of incorrect decisions.
SHIMMER successfully observed Polar Mesospheric Clouds (PMCs) during the northern season of 2008, measuring diurnal variation with a single peak per day. The observation is unique among satellites that have studied PMCs and has important implications for inferring long-term trends from historical space-based observations.
A national survey by North Carolina State University and Arizona State University found significant public support for nanotechnology applications improving human health. However, there was little support for non-health research endeavors, highlighting the need for differentiated views on public policies and research funding.
A multi-center phase II clinical trial found improved survival in patients with advanced non-small cell lung cancer treated with chemotherapy and targeted therapies bevacizumab and cetuximab. The combination showed no safety concerns, indicating a potential future treatment option for lung cancer.
SLU researchers found a way to get a promising treatment for Alzheimer's and stroke into the brain, reversing symptoms. They discovered a unique approach to delivering drugs past the blood-brain barrier, which had blocked treatments in the past.
Researchers at Queen's University Belfast trace the family tree of octopuses, revealing a link between climate change and their global distribution. The study suggests that many deep-sea species evolved from Antarctic ancestors, highlighting the impact of thermohaline circulation on marine biodiversity.
A new study found that vitamin C supplements can lower concentrations of CRP, a central biomarker of inflammation linked to heart disease and diabetes. The study also found no benefit from daily doses of vitamin E.
The 'Cradle & Grave' white paper examines seismic changes in birth, health, and death trends, influencing the future administration and Americans contemplating their futures. Gary Stockman highlights outdated assumptions shaping unrealistic expectations and poor choices.
Researchers have identified a new biomarker for heart failure, resistin, which can independently predict an individual's risk of developing the condition. Resistin levels were found to increase the risk of new-onset heart failure by 38% and were a stronger predictor than other inflammatory markers.
Researchers at University of California, San Diego identify cells responding to illumination by producing dopamine, a chemical message controlling pigmentation in tadpoles. This finding suggests that stimulating specific neural circuits could selectively alter brain chemistry to remedy low levels of neurotransmitters underlying human a...
Researchers found that patients with gastrointestinal stromal tumors (GIST) respond differently to medications depending on their unique genetic makeup. The study suggests that developing individualized treatment plans tailored to the specific mutations in each tumor could improve patient outcomes. Additionally, the analysis of Sutent'...
A new study by Tel Aviv University and the University of Utah found a significant link between brain cancer and family history. Researchers discovered that a four-fold increase in risk exists for individuals with a family history of brain tumors, highlighting genetic predispositions.
Scientists at Carnegie Institution's Geophysical Laboratory found that highly oxidized iron in mantle minerals is crucial for heat transfer in the lower mantle. The discovery challenges current models of mantle dynamics and has significant implications for understanding material movement throughout the planet.
Researchers have developed nematode-resistant varieties of bell peppers, such as Charleston Belle and Carolina Wonder, which can be used as viable alternatives to methyl bromide for managing southern root-knot nematode. These varieties are stable in sub-tropical climates and can increase the availability of parasite-resistant vegetables.
Medicare's funding cut for dual-energy X-ray absorptiometry (DXA) may discontinue critical health services for osteoporosis patients. The test is essential for identifying those at risk and monitoring bone health, potentially leading to increased fractures and costs.
A new study found that hospital mortality rates for women and men have narrowed significantly over the last decade, particularly among younger patients. Women under 55 years old showed a 53% reduction in mortality, compared to 33% for men of the same age group.
Reagan's presidency is assessed under eight headings of public concern: welfare state, taxation, national security, the presidency, personnel, party politics, political leadership, and the person. Despite his impact on tax rates and national security, Reagan's legacy is complicated by concerns over big government and executive power.
A belief in luck was not sufficient to entice consumers to a lucky draw over other sales strategies, according to researchers Gerard Prendergast and Edmund Thompson. Consumers who personally feel lucky are more likely to participate in lucky draws.
A novel protein marker identifies rare adult liver stem cells whose ability to regenerate injured liver tissue has the potential for cell-replacement therapy. The finding offers significant implications for treating chronic liver disease in the future.
Purdue University researchers are working on a new technique called MAGIC to identify gene combinations that increase disease resistance and stress tolerance in crops. By analyzing the genetic diversity of maize, they aim to engineer plants that can withstand most diseases and improve crop yields.
A nationwide study on the interactions of genes, environment and lifestyle has received widespread public support, with 84% of respondents in favor and 60% willing to participate. The study's findings suggest that factors such as individual research results and compensation play a significant role in increasing willingness to participate.
A retrospective study found that gender matching in heart transplantation leads to improved short- and long-term survival rates. Male recipients receiving hearts from male donors had a 61% cumulative chance for survival, while female recipients of female donor hearts had a 25% drop in 30-day death rate.
A new study led by Duke University researchers found that restored wetlands have decreased soil bacterial diversity, but this decrease represents a return to biological health. The composition of these populations can reflect the status of wetland functioning and serve as an indicator of restoration success.
Research highlights increased risk of post-MI death among African-American patients with acute myocardial infarction and previously treated depression. Persistent depressive symptoms at the time of MI hospitalization may indicate a more severe or recurrent condition.
Researchers found that adding a visual or auditory signal can increase the perception of an electrical stimulus, even if it's not initially detected. Multisensory integration plays a crucial role in this process, modifying peripheral systems to enhance our understanding of the world.
Researchers from the University of Leicester and Cambridge have solved the mystery of how soft tissues in 500-million-year-old fossils were preserved. The team found that deep heating transformed delicate organic tissues into mineral-rich sites, revealing intricate details such as gills, guts, and eyes.
A study published in Human Reproduction found that placebo acupuncture resulted in a significantly higher overall pregnancy rate (55.1%) compared to real acupuncture (43.8%) in patients undergoing IVF. The researchers suggest that placebo acupuncture may have a real effect, contrary to its inert control status.
Researchers at Medical University of South Carolina present a new theory that may lead to effective heart failure treatments by identifying the role of matrix metalloproteinases (MMPs) in the disease. The study suggests that MMPs, similar to those found in cancerous tumors, contribute to the progression of heart failure, leading to the...
Research at Ohio State University found women sexually harassed most often in work groups with a nearly equal mix of males and females. Women in these situations were more likely to experience taunting, patronizing, and predatory behaviors.
Dr. Mariano Belluscio, a graduate research scientist at Rutgers University, has been awarded the Pew Latin American Fellows Program in Biomedical Sciences. He explores neural activity patterns in memory and planning, shedding light on fundamental mechanisms of brain function.
A recent study published in The Lancet found that the MRKAd5 HIV-1 gag/pol/nef vaccine failed to provide any protection against HIV infection. However, immune responses mounted by T-cell-based vaccines alone may not be sufficient to protect against HIV infection or disease.
Breast cancer cells closer to blood vessels are more aggressive and directed in their invasiveness, according to a new study. The research provides detail on how cancer cells invade surrounding tissue and reach blood vessels, offering insights into early stages of metastasis.
A comprehensive study reveals that Chinese Americans face a 'glass ceiling', with lower occupational stature and success compared to their efforts. Despite high education levels, they earn less than White counterparts in certain fields, highlighting the need for tailored support.
A new highly sensitive infrared spectrometer has been developed using nonlinear optics, offering 100 times higher sensitivity than current commercial devices. The device eliminates the need for cryogenic cooling, making it practical for various industrial applications.
Researchers from Cedars-Sinai Heart Institute will share findings on regenerating heart tissue using stem cells, a mutant gene therapy strategy to protect against heart disease, women's rapid onset of heart disease, and the effectiveness of new medication prasugrel in preventing ischemic complications.
The launch of BioMed Central's Genome Medicine journal marks a significant milestone in the field of personalized medicine. The journal will focus on the latest technologies and findings impacting human health and disease, covering topics such as genomics, epigenetics, and computational approaches to disease management.
A recent study by Children Now found that only 13% of educational programming for children is rated highly educational, with most shows offering limited value. The study analyzed 120 episodes across 40 program titles and found that commercial stations are failing to meet their obligation to deliver high-quality educational content.
The AAAS Science Journalism Awards honored excellence in science reporting, including a series on memory and the brain, efforts to search for life elsewhere in the cosmos, and an investigation into the effectiveness of anti-cholesterol medications. The winners received $3,000 and a plaque at the 2009 Annual Meeting.
A large waist can significantly increase mortality risk by up to 34% in men and 24% in women. The study suggests doctors should measure waistlines as part of standard health checks.
Entrepreneurs are riskier decision-makers than managers, according to a study published in Nature. The study found that entrepreneurs' 'functional impulsivity', or ability to make quick decisions under stress, is linked to brain neurochemistry and may be possible to teach or enhance with pharmaceuticals.
Researchers found that global warming may not be the primary cause of widespread amphibian declines, contradicting previous widely-held views. The study suggests alternative factors, such as a fungal infection and pesticide use, may be driving these extinctions.
A Virginia Tech chemist will share a portion of pharmaceutical royalties with Madagascar, supporting biodiversity conservation and cancer research in the country. The research, led by David G.I. Kingston, aims to find new anticancer agents from Madagascar's unique plant and animal species.
Researchers found that patients who received both intravenous thrombolysis and endovascular interventions experienced significantly lower mortality and greater improvement in neurological ability. The study suggests that combining these treatments could be a game-changer for stroke patients, especially those under 80 years old.
A new study finds that air pollution has a significant impact on heart health, with personal exposure leading to increased blood pressure and systolic blood pressure. Community-level exposure is also associated with impaired blood vessel functioning, potentially contributing to sudden heart attacks, strokes, and heart failure.
Researchers found that direct implantation of mesenchymal stem cells did not remyelinate the damaged area, but still consider MSCs a promising tool for neurological disorders due to their pre-clinical efficacy in treating stroke and MS.
A landmark clinical trial of an HIV vaccine candidate found no protection against infection, despite generating a strong immune response. The study, sponsored by Merck & Co., Inc. and the National Institute of Allergy and Infectious Diseases, analyzed the effects of the vaccine on study participants' immune responses and viral load.
A new study from Indiana University's Kinsey Institute explores the link between hormone levels and brain responses to masculinized versus feminized male faces. The research found that neural activation in response to face stimuli is sensitive to facial masculinization, with differences appearing strongest during the follicular phase c...
Researchers successfully tested the live broadcast of surgeries using the Internet2 network, enabling real-time video transmission to multiple locations. This technology has the potential to revolutionize medicine by reducing travel costs for physicians and enhancing patient care.