Articles tagged with Heart
According to American College of Cardiology guidelines, several factors increase cardiovascular risk, including obesity, physical inactivity, smoking, elevated blood pressure, and diabetes. World Heart Day promotes awareness of these risks and encourages individuals to adopt healthy habits such as regular exercise, balanced diet, and q...
The Gladstone Institutes' team supplied original stem cells for the exhibit and trained museum staff on techniques to activate cells. The exhibit showcases the development of cardiac myocytes from undifferentiated state to pulsating heart cells.
A new study by Beth Israel Deaconess Medical Center reveals a significant link between heavy drinking and atrial fibrillation. The research, which analyzed data from 16,415 individuals, found that men who drank 35 or more alcoholic beverages per week had a 45% increased risk of developing the hazardous heart rhythm.
Researchers are investigating a drug that may block the deadliest form of inflammation in heart bypass patients, including those who have had previous strokes or heart attacks. The study focuses on high-risk patients and pediatric cases, aiming to improve outcomes and reduce morbidity related to heart surgery.
Researchers identified a genetic link between inflammation and an increased risk of stroke after heart surgery. A specific combination of polymorphisms in genes responsible for C-reactive protein and interleukin-6 was found to be associated with a higher rate of stroke in patients.
Researchers at Thomas Jefferson University have discovered a potential biomarker, GRK2, that can predict the severity of heart failure. Elevated levels of this enzyme in the blood are associated with more severe heart failure and may help identify patients who would benefit from specific treatments.
A recent study published in the American Journal of Roentgenology found that MRI is more comprehensive than SPECT in assessing heart damage in patients with hypertrophic cardiomyopathy. MRI was able to detect small areas of heart damage and provide important data on cardiac function, whereas SPECT only became relevant if no abnormaliti...
A new study found that not enough exercise in women can lead to serious heart problems and death, with those who cannot achieve 85% of their age-predicted fitness level being twice as likely to die. The researchers developed a chart for women to interpret their exercise capacity based on normative values for their age.
A new review of the American College of Cardiology and American Heart Association guidelines aims to streamline diagnosis and treatment of acute coronary events. The goal is to provide faster treatment that may even prevent a heart attack or damage to the heart before it happens, benefiting millions of patients each year.
Key findings highlight the importance of including women in clinical trials due to differences in response to drug therapy, such as higher levels of adverse reactions and varying mortality rates. This lack of data affects treatment strategies, with many drugs prescribed to women adapted from studies conducted mainly in men.
Recent studies using transgenic mice have shown that overactive Akt1 can lead to cardiac dysfunction and hypertrophy. In contrast, Akt1 is critical for adaptive angiogenesis in the heart after ischemia. The research highlights the importance of understanding Akt1's role in regulating cardiovascular function.
Researchers have discovered that during early stages of heart failure, the heart uses too much fatty acid and not enough carbohydrate; later on, it doesn't use enough fat. This new knowledge can lead to better treatments, but the existing drugs don't remedy the inefficiency.
Researchers at Duke University Medical Center have made a breakthrough in understanding the role of phosphoinositide 3-kinase (PI(3)K) in heart failure. They found that preventing PI(3)K's activation could block the loss of heart receptors, potentially improving heart function in patients with heart failure.
The European Commission's Heart Health Conference aims to promote cardiovascular disease (CVD) prevention measures across Europe. The conference concluded with key actions for member states and the EC to implement to improve cardiovascular health in Europe, emphasizing the need for a long-term approach through public health strategies.
A new study published in the New England Journal of Medicine found that daclizumab can reduce organ rejection in heart transplant patients by 25%. The treatment also showed a lower rate of bacterial infections compared to placebo. Researchers believe this incremental step will help improve outcomes for heart transplant patients.
Caffeine can increase heart activity, making it harder to see cancerous lesions on scans. Patients who consumed coffee before scans had higher myocardial uptake than those with low or no caffeine intake.
A recent UCLA study has found a significant association between obesity and impaired coronary circulatory function, highlighting the importance of early detection and monitoring. Quantitative PET imaging may help identify at-risk individuals, enabling targeted interventions to prevent cardiovascular events.
A large European survey of 11,000 patients admitted with heart failure found that only two thirds had received a heart tracing, while four out of ten patients lacked an ACE inhibitor prescription. Multidisciplinary treatment can cut hospital admissions and deaths from heart failure.
A study of 59 patients with persistent atrial fibrillation found a strong link between Helicobacter pylori infection and elevated C reactive protein levels, suggesting chronic gastritis may predispose to atrial fibrillation. The researchers also noted that H pylori has properties enabling it to evade the immune system.
Researchers at Washington University School of Medicine found that inflammation is the cause of postoperative atrial fibrillation, a rapid and irregular twitching of the upper chambers of the heart. Anti-inflammatory therapy may prevent or lessen this condition by increasing uniformity of electrical impulses in the atria.
Researchers have discovered a link between mutations in the MRTF-B gene and congenital heart disease in mice, which mimics human conditions such as truncus arteriosis. The study found that defects in cardiac neural crest cells lead to impaired blood vessel development and outflow tract defects.
A significant association was found between air pollution and an increased risk of ventricular tachyarrhythmias among patients with implanted cardioverter defibrillators. The risk was particularly high when particulate air pollution, black carbon, nitrogen dioxide, and sulfur dioxide were present.
Researchers at Duke University have developed a new 3-D cardiac imaging probe that offers sharper, high-contrast images and real-time guidance for therapeutic treatment devices. The probe's ability to generate three-dimensional images may shorten patient time in clinics and reduce radiation exposure.
A recent study found that patients taking SSRIs before heart surgery have higher mortality rates four years later. The researchers suggest that depression itself is the primary cause of increased mortality, rather than medication use. The study recommends closer monitoring and treatment for depressed patients undergoing heart surgery.
Researchers discovered non-coronary findings in 60 patients via heart CT scans, including lung cancer and aneurysms. Radiologists' training is crucial for early disease management and improved patient prognosis.
A study at Duke University Medical Center found that genetic variations in platelet surface receptors and coagulation proteins are associated with increased post-operative bleeding. This discovery may lead to genetic screening as a tool for pre-operative evaluation of heart surgery patients.
A six-week cycling study found that regular exercise activates hundreds of genes in young, healthy men, some linked to diabetes and cardiovascular disease. The study also showed that individuals who improved their performance most activated more genes in the muscles, a phenomenon not previously seen.
Researchers found that a personalized physical exercise and Mediterranean-style diet plan improved vascular structure and function in volunteers with pre-clinical cardiovascular disease risk factors. Average VO2 max increased by 3.2 mL/min/kg, while body weight decreased significantly.
Researchers discovered that a 'fickle' enzyme plays both protective and detrimental roles in the heart. When its cofactor is present, it helps regulate blood flow and heart function, but without it, the enzyme produces factors contributing to oxidative stress.
A recent study found that only three out of 21 streptokinase preparations met the minimum requirements of the European Pharmacopoeia, highlighting the need for stricter calibration and monitoring. The lack of reliable testing methods and inadequate post-marketing control allow substandard drugs to enter the market.
Researchers found that more than half of patients with heart failure have normal ejection fractions but still experience symptoms. The study suggests that conditions like anemia, obesity, and hypertension may play a role in causing heart failure.
The International Society for Heart and Lung Transplantation has created new, comprehensive guidelines to help organ centers update their policies. The guidelines aim to bridge patients to transplant by offering pharmacological, surgical, and device-based interventions.
The study found that women who received stents experienced a significant reduction in major adverse cardiac events and death rates compared to those treated with balloon angioplasty. Stenting was also shown to decrease the need for re-intervention, a critical factor contributing to higher mortality risk in women.
A new pump device, partnered with stem cell technology, aims to address heart failure and improve heart function. Research on ventricular assist devices (VADs) and pediatric devices is also ongoing, with a focus on developing smaller devices for children and improving outcomes.
A new study from Rice University found no independent relationship between Lp(a) levels and coronary calcium in either whites or African-Americans, suggesting an unknown mechanism may be at work. The study used a large multiethnic dataset of Dallas County residents to examine the link between Lp(a) and heart-attack risk.
A new study published in Nature Medicine shows that infants with Type O blood can accept hearts from donors with Type A blood due to their immature immune system. This breakthrough allows for greater donor compatibility and more successful transplants.
A study published in the Journal of Clinical Investigation reveals that HDL (high-density lipoprotein) activates an enzyme called eNOS, leading to a cellular signal that depends on cholesterol efflux. The activation of eNOS is mediated by two intact domains of SR-BI, which act as 'cholesterol sensors' triggering cellular events.
The European Society of Cardiology has launched a new initiative called Women at Heart to improve the handling of women with cardiovascular disease. The initiative aims to highlight the growing burden and under-appreciation of women's heart disease, and promote better understanding and treatment among medical professionals.
Research suggests that moderate red wine consumption (2-3 ounces per day) may have beneficial cardiovascular effects due to its high content of polyphenols. Polyphenols are also found in berries, green tea, and chocolate and can help prevent cell deterioration, plaque buildup, and blood clotting.
A recent study found that cardiologists significantly underreported racial and ethnic disparities in care, with only 12% reporting disparities in their own hospitals. The study suggests that increasing awareness through practice data analysis can help address these disparities.
Researchers found that black high-risk patients were more likely to receive older treatments and less likely to receive newer drugs, including glycoprotein IIb/IIIa inhibitors and clopidogrel. Despite these disparities, short-term outcomes did not differ significantly between blacks and whites.
A study by Emory University Health Sciences Center found that drug eluting stents are at least equivalent to vascular brachytherapy in preventing restenosis. SES treatment had a lower incidence of heart attacks and major adverse cardiovascular events compared to conventional VB treatment.
Orqis Medical's Cancion CRS therapy has shown promising results in improving cardiac index and pulmonary capillary wedge pressure in patients with severe heart failure. The therapy provides continuous aortic flow augmentation, enabling progressive hemodynamic improvement without taking over the heart's function.
Researchers found that African-American patients receive lower rates of cardiac catheterization for heart attacks compared to white patients, despite disparities narrowing over time. The study highlights the need for improved patient education and dialogue with medical teams to address racial disparities in healthcare.
A 12-week Tai Chi exercise program showed high completion rates and health benefits among 27 Chinese women with cardiovascular risk factors. The program's success was attributed to cultural relevance, accessibility, and the Yang Style of Tai Chi.
Researchers found that women with diabetes had over two and a half times the risk of heart disease compared to women without diabetes. Men with diabetes had about a 90% higher risk of dying from CHD as men without diabetes.
Women with acute coronary syndrome are being prescribed aspirin, beta-blockers, and statins as frequently as men, according to a recent study. However, significant disparities remain in the use of lipid-lowering medications, with women living significantly longer after their hospitalization.
Researchers found that marital strain can increase a woman's risk of death from any cause, with self-silencing during conflict being a significant factor. Married men also had a lower risk of developing heart disease compared to unmarried men.
Researchers have discovered a potential link between protease inhibitor drugs and heart rhythm irregularities in HIV patients. The study, published in The Lancet, found that certain drug combinations could trigger adverse heart effects, highlighting the need for closer monitoring of vulnerable individuals.
A new study published in the Journal of Cardiac Surgery found that older patients who receive a heart transplant fare just as well as younger counterparts, even many years after surgery. The study showed no statistically significant differences between heart transplant recipients aged over 60 and those under 60.
A report by the British Cardiac Society highlights the challenges women face in pursuing careers in cardiology due to long hours, lack of flexible training, and sexism. The specialty is losing talented female applicants, with only 9% of those applying for specialist registrar posts being women.
The Sulpizio Family Cardiovascular Center will offer advanced cardiac care with a range of treatment options and expanded access to clinical trials. Construction is set to begin in 2009, with plans for the new facility including diagnostic and treatment areas, office space, and 16-20 examination rooms.
A new math model of heart cells has identified a novel calcium pathway that regulates cardiac electrical activity and is linked to arrhythmia research. The study, published in Circulation, provides a valuable tool for understanding the relationship between calcium handling and cardiac arrhythmias.
Researchers identified a specific antibody causing congenital heart block, targeting the p200 part of the Ro protein. The level of this antibody in mothers correlates with the degree of damage to the heart, highlighting a potential marker for high-risk pregnancies.
Researchers discovered that failing hearts experience an energy deficit due to a 50% reduction in ATP energy supplied by creatine kinase. This finding suggests new treatments may target the energy supply to improve heart function.
Hermes A. Kontos and John R. Marler receive prestigious awards, while Hong Li and Shelagh Coutts win research accolades for their work on stroke mechanisms and treatment.
Studies show that hospitals implementing GWTG–Stroke programs experience significant improvements in secondary preventive measures, including anticoagulation for atrial fibrillation and treatment with aspirin-like drugs. Timely intravenous tPA use also increases by up to 89%.
A study found that doctors underestimate women's heart risk, leading to less preventive care. Despite having the same calculated risk as men, women are more likely to be classified as having lower risk and receive less preventive care.
Researchers found significant differences in mitral valve tissue between healthy and congestive heart failure patients, affecting the valve's strength and hydration levels. These changes may contribute to recurring surgical outcomes for patients with mitral regurgitation.
Researchers at Johns Hopkins Medicine found that sildenafil can treat enlarged hearts by blocking the breakdown of cyclic GMP, a key molecule involved in heart stress. The study showed significant improvements in heart function, including increased contractility and cardiac output, even after hypertrophy had developed.