Articles tagged with Human Heart
Researchers at the University of Toronto have developed a new method to mature human heart cells by applying electrical pulses and simulating fetal heart rates. This discovery offers a fast and reliable way to create mature human cardiac patches for various applications, including drug screening and transplantation.
Researchers use CT scans to recreate detailed 3D models of human hearts, enabling the study of cardiac anatomy and function. This digital library can aid in the design of cardiac devices and improve treatment outcomes.
Researchers from the University of Leeds used the abdominal fetal ECG device developed by The University of Nottingham to create a comprehensive model of a fully functioning fetal heart. The study found that human hearts develop more slowly compared to other mammals, with little organisation in their walls until 20 weeks into pregnancy.
Researchers at Washington University in St. Louis have discovered genetic differences between men's and women's hearts, finding that women with failing hearts have weaker gene expression systems than men, while men are more susceptible to atrial fibrillation and long-QT syndrome.
Researchers at Boston Children's Hospital found that young humans can generate new heart muscle cells, challenging the accepted wisdom on human heart growth. The study's findings offer a potential new approach to treating heart failure in children by stimulating cardiomyocyte proliferation.
Researchers at Stanford Medicine have engineered human heart cells that respond to light, using optogenetics. These light-sensitive cells could lead to a new class of pacemakers and genetically matched replacement heart cells, potentially replacing traditional electrical pacemakers and addressing tissue rejection issues.
Researchers used human hearts to replicate a mouse study on KATP ion channel drug targets, finding one target ineffective in humans. The findings underscore the importance of translating results from animal models to clinical trials in cardiovascular research.
Researchers have found that human heart cells develop into adulthood around age 6, with the percentage of new cells decreasing significantly with age. This discovery may lead to new pharmacological strategies to stimulate heart cell regeneration and complement cell transplantation.
Researchers have identified a connection between fruit fly genetics and human heart disease, revealing that certain genes play a role in both embryonic and adult heart function. The study found TBX20 mutations in humans with structural congenital heart abnormalities and heart muscle dysfunction, suggesting its potential involvement in ...
Increased expression of an accessory subunit of L-type calcium channels is linked to altered channel behavior in human heart failure. Researchers have identified a causal role for this protein overexpression in the development of cardiac dysfunction.
Researchers at Duke University Medical Center have developed a method to visualize the heartbeat of fruit flies, enabling them to identify genetic mutations associated with human heart disease. The team inserted a mutated gene into the fly genome and observed its effects, revealing similarities with human dilated cardiomyopathy.
A researcher created a model to simulate the dynamics of heart rhythm disorders, including ventricular tachycardia and fibrillation. The model revealed that only six spiral waves are present in the heart during fibrillation, contradicting previous assumptions about its chaotic nature.