Articles tagged with Muscles
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A study found that maximal voluntary force produced by a finger is independent of movement speed, contradicting long-held theories. This paradoxical result has implications for human rehabilitation and robot hand design, suggesting that neuromuscular systems can be pushed to their limits even in seemingly simple tasks.
A systematic review by Cochrane Researchers found that rubefacients, commonly used for muscle pain, are ineffective for chronic and acute pain due to skin irritation. The study analyzed data from 16 trials involving over 1,200 people, concluding that larger, higher-quality trials are needed to establish their effectiveness.
A new study published in CMAJ found significant muscle injury in patients taking statins, even in those without elevated creatine phosphokinase levels. Researchers suggest a subgroup of patients may be more susceptible to statin-associated myotoxicity and call for alternative treatment strategies.
Scientists have found that mechano growth factor (MGF) stimulates muscle development by activating stem cells in response to exercise. MGF has great potential as a therapeutic treatment for age-related muscle loss and diseases such as muscular dystrophy, ALS, and cancer.
Research explores how exercise at high altitudes impacts the body's response to decreased oxygen levels. The findings reveal adaptations that help maintain oxygen delivery to muscles during exercise and long-term benefits for athletes training at moderate altitude.
Researchers found marine mammals have higher myoglobin solubility due to increased net positive charge, and stronger divers have more histidine, aiding lactic acid management. This adaptation helps marine mammals cope with aquatic life demands.
Researchers have produced video footage of a male nematode worm preparing to mate with a hermaphrodite, showcasing the complex process. The study revealed that the male uses acetylcholine to regulate tail muscles for an exploratory embrace, and then searches for the vulva before mating commences.
Scientists found that adult muscle stem cells can regenerate muscles after injury without the two key embryonic muscle cell genes Pax3 and Pax7. This discovery challenges current research on muscular dystrophy and regenerative medicine, suggesting that age-matched stem cells may be more effective for therapy.
A new study found that people with stroke impairments experience delays in gripping and releasing objects, but using an arm support device can improve release speed. Active muscle-stretching exercises also showed promise, helping with grip initiation but delaying release.
A new study finds that blocking the muscle growth-limiting hormone myostatin can decrease body fat and promote resistance to atherosclerosis in mice. The results show significant reductions in obesity-related biomarkers, including fasting blood sugar, insulin levels, and cholesterol levels.
Researchers have discovered a new drug, Debio 025, which is as effective as current treatment options but without the risk of infection and immunosuppression. The study found that Debio 025 protects mice from muscle-wasting diseases similar to human muscular dystrophy.
Researchers found that enzyme MuRF1 selectively degrades thick filaments in muscle, while thin filaments are bypassed. This ordered process enables the muscle to maintain its structure and function during atrophy.
A new study finds that lowfat chocolate milk is an effective post-exercise recovery aid for soccer players, providing equal or superior muscle recovery compared to a high-carbohydrate recovery beverage. Chocolate milk's unique blend of protein and carbohydrates helps refuel exhausted muscles and reduce exercise-induced muscle damage.
Researchers have discovered that crustaceans use resilin springs to simplify brain control of limb movements, allowing for more efficient energy storage and reduced nervous system activity. This unique mechanism enables crabs and crayfish to coordinate their limb movements at an impressive 20 times per second.
A new study suggests that drinking tart cherry juice before and after exercise can significantly reduce muscle pain, with a clinically significant difference of 2 points on a pain scale. The researchers attribute the benefits to the fruit's natural anti-inflammatory power due to its antioxidant compounds.
Researchers at UCSF have identified a specialized protein called CHC22 that controls the formation of GLUT4 storage compartments in human muscles. This discovery highlights key differences between humans and mice and has implications for developing better models for studying type 2 diabetes.
Researchers at Western Australian Institute for Medical Research (WAIMR) have cured mice with a congenital myopathy disorder that causes babies to be born without normal muscle function. They achieved this by replacing missing skeletal muscle actin with heart actin, allowing the mice to live normally into old age.
Researchers found that a heart muscle protein, ACTC, can compensate for a lack of skeletal muscle protein, ACTA1, in mice with myopathy. Mice with this compensation survived more than three months and showed improved endurance, locomotor performance, and muscle strength.
Doctors warn of muscle problems caused by excessive cola consumption, citing cases of hypokalaemia and paralysis. The review of patients who consumed up to nine litres of cola a day highlights the need for safer drink options and moderation.
A potential vaccine for Alzheimer's disease has been shown to slow the weakening of muscles associated with inclusion body myositis (IBM) in mice. The study found reduced levels of beta amyloid and oligomeric beta amyloid, a more toxic form, in the skeletal muscle tissue.
A Queen's University research team challenges the common belief that massage after exercise improves circulation to the muscle and removes lactic acid. Their study reveals that massage actually impairs blood flow to the muscle after exercise, resulting in impaired removal of lactic acid.
Researchers link muscle decline to elevated carbon dioxide in blood of patients with lung diseases, discovering surprising effects including increased lifespan and dynamic gene changes. High CO2 levels may impact treatment strategies for lung conditions.
A team of researchers at Northwestern University discovered a new approach to control movement in limbs by grouping muscles, which could simplify the restoration of muscle movements in people with paralysis. By reducing the number of variables, this method can achieve similar results as controlling individual muscles.
A new study found that oral contraceptive use impairs muscle gains in young women, with lower hormone levels and elevated cortisol concentrations. The researchers also noted significant differences in lean mass gains between OC users and non-users.
Researchers successfully transferred a gene to produce a protein necessary for healthy muscle fiber growth, increasing muscle-fiber size and producing the needed protein for at least six months. The findings demonstrate the feasibility of gene therapy for treating limb-girdle muscular dystrophy and other muscle disorders.
Researchers at Boston Children's Hospital have created a slow-release anesthetic drug-delivery system, showing promise for prolonged pain relief without toxicity in rats. The formulation, using liposomes to package saxitoxin, produced nerve blocks lasting two days or seven days when combined with dexamethasone.
Researchers found that sugary drinks and tasteless carbohydrates can significantly improve endurance event performance. Athletes given glucose or maltodextrin drinks outperformed those on 'disguised' water by 2-3%.
Researchers analyzed human muscle tissue from SMA patients to understand transcriptional changes. The study found distinct expression signatures for severe and mild forms of SMA, revealing different phases of atrophy and hypertrophy in muscles affected by each form.
A new study suggests that astronauts need to modify their workouts to avoid extensive muscle loss during long-duration missions in space. Muscle biopsies taken from astronauts revealed an average of 15% muscle mass loss and 20-30% loss of muscle performance, posing risks to crewmembers' health.
Despite exercising for three months, octogenarian women failed to increase muscle mass, but showed improved efficiency in activating and synchronizing their muscles. The study suggests that it's essential to build as much muscle mass as possible earlier in life to ensure more strength in later years.
According to evolutionary biologist Alan Walker, human fine motor control limits strength compared to chimps. Humans use fewer muscle fibers for tasks, while chimps use more due to less motor neuron control. This allows humans to conserve energy and perform delicate tasks, but may also limit their physical endurance.
A team of American researchers has developed a genetic switch that allows mutations or light signals to be turned on in muscle stem cells, enabling monitoring of muscle regeneration in living mammals. This breakthrough could lead to the creation of a genetic switch or drug for humans to grow new muscle cells and treat muscular dystrophy.
Researchers studying the genetics of exercise have identified about 200 genes that play a role in adapting to physical activity. These genes may hold the key to understanding muscle diseases such as muscular dystrophy, and could lead to new treatments for individuals with limited genetic ability to adapt.
The find pushes back the origins of modern octopus by tens of millions of years, revealing a more primitive ancestor with fleshy fins. The fossils are remarkably well-preserved, showing similar characteristics to living species, providing valuable evolutionary information.
Scientists have developed a successful treatment for dogs with Duchenne muscular dystrophy using 'exon skipping' technology, which covers up genetic errors. The treatment involves injecting tailor-made DNA patches into the bloodstream, improving muscle functioning and reducing deterioration in skeletal muscles.
A new technique for staging bladder cancer has shown encouraging results, accurately identifying tumors in 95.2% of specimens and avoiding unnecessary bladder removals in some cases. The technique uses an antibody to distinguish between deep muscle layers, reducing the risk of mistaken diagnoses.
A CU-Boulder research team has identified a type of skeletal muscle stem cell that contributes to the repair of damaged muscles in mice. The newly identified stem cells, dubbed satellite-SP cells, renew the satellite cell population after injection into injured muscle cells, contributing to recovery of muscle tissue.
Researchers have developed a world-first procedure to regrow muscles in a mouse model, which could be applied to human tissue-based illnesses such as liver or brain diseases. The technique strengthens adult stem cells' ability to regenerate damaged tissue by making them resistant to chemotherapy.
A University of Illinois study found that a moderately high protein diet outperforms low-carb diets for weight loss and maintenance. Participants on the protein-rich diet lost more body fat and preserved muscle mass, reducing triglyceride levels and improving overall health.
Researchers discovered that male Australian crayfish use deceptive signals to advertise their strength, cheating rivals with weaker but larger claws. This behavior comes at a cost, as large claws may hinder the males' ability to escape danger.
Researchers identified the location of genetic material responsible for producing nNOS, a critical component for muscle health. The discovery could lead to more effective gene therapy for Duchenne muscular dystrophy patients.
A new study suggests that high levels of myostatin produced by muscle tissue in extremely obese individuals may contribute to the development of insulin resistance and Type 2 diabetes. Muscle loss is a key indicator of this transition, and understanding its role in metabolism is crucial for finding effective treatments.
A study by U of T psychologists reveals a connection between moral disgust and primitive emotions related to poison and disease. The research found that people display similar facial movements in response to both moral and primitive forms of disgust.
The high-quality protein in eggs contributes to muscle strength by building and preserving muscle mass. Additionally, it provides sustained energy due to its steady release of amino acids without causing a surge in blood sugar levels.
Researchers found no increased risk of Guillain-Barré syndrome after HPV vaccination, but cases still warrant careful monitoring. The study analyzed data from the Vaccine Adverse Event Reporting System and reported 36 cases within six weeks of vaccination.
Targeted muscle reinnervation (TMR) appears to enable improved control of prosthetic arms for patients with arm amputations. The study, published in JAMA, found that TMR patients achieved high motion selection and completion rates, similar to those of control participants.
Researchers mapped every neuron in a small muscle of mice, finding unique neural circuitry even within mirror-image tissues on the same animal. The study suggests that the mammalian nervous system may be more primitive and flexible than previously thought.
A new study found that teenage girls with higher vitamin D levels had improved muscle function, specifically jump speed and power. The research suggests that vitamin D may be a super nutrient beyond its role in keeping bones strong.
A new study found a positive relationship between vitamin D levels and muscle power, force, velocity, and jump height in adolescent girls. The researchers measured serum vitamin D levels in 99 adolescent girls and used jumping mechanography to assess muscle power.
A systematic review found motor control exercises can significantly reduce pain and disability in patients with persistent low back pain. These exercises help regain control of trunk muscles, leading to improved physical activity and positive effects over time.
Researchers found that fat molecules clog up muscle cells' cytosol but not mitochondrion. By increasing mitochondrial ability to burn fat, muscles become more responsive to insulin. The discovery opens doors to developing new therapies for Type 2 diabetes.
A new study reveals that spitting cobras create complex geometric patterns of venom when striking, which are actively produced by the snake's muscles. This allows them to hit their targets with remarkable precision, making contact with an attacker's eyes where it causes severe pain and possibly blindness.
Researchers are sending worms to the International Space Station to study muscle atrophy in zero gravity. The goal is to understand why astronauts experience dramatic muscle loss and potentially develop new treatments for muscle wasting diseases.
Researchers have discovered a new therapeutic target that improves deteriorating skeletal muscle tissue caused by SMA. The therapy enhances muscle strength, improves gross motor skills, and increases the lifespan in a SMA model. By inhibiting myostatin, a protein that limits muscle growth, the treatment reduces symptoms of SMA.
The multifidus muscle's unique packing design allows it to serve as a critical stabilizer of the lumbar spine, providing strong support for the lower back. This discovery could lead to improved therapeutic interventions, such as physical therapy targeting specific muscles, to treat spinal disorders and reduce lower back pain.
A study by Ohio State University researchers found that the molecule miR-29 is essential for muscle repair and maturation, but its absence is linked to rhabdomyosarcoma cancer. Raising miR-29 levels in cancer cells slowed tumor growth and induced maturity.
Researchers found that laminin-111 restored regenerative capacity in a mouse model for alpha 7 integrin congenital myopathy. The protein promotes muscle cell health and survival by interacting with the extracellular matrix.
Researchers discovered that nerves connecting to flexor muscles are guided by a protein family called ephrin-B, which is closely related to the previously identified ephrin-A protein. This finding provides insights into how nerves form and could lead to new strategies for treating disorders such as epilepsy and mental retardation.
Research suggests FHL1 enhances transcription factor NFATc1 activity to promote muscle hypertrophy. Overexpressing FHL1 in mice and myoblasts resulted in increased strength and endurance.
Scientists have successfully transplanted a single adult stem cell into a live mammal and shown that it can self-renew and repair damaged tissue. The study used genetically engineered cells to track their dynamics, demonstrating the ability of these cells to proliferate and engraft into injured muscle tissue.