Articles tagged with Nervous System
Bentham Science journals Central Nervous System Agents in Medicinal Chemistry and CNS & Neurological Disorders – Drug Targets accepted for PsycInfo database indexing, enhancing global visibility of research. PsycInfo provides extensive coverage of behavioral and social sciences, making this move a significant step forward.
Researchers found that female locust's digging valves wear down significantly despite being used only 3-4 times in a lifetime. The study demonstrates the 'good enough' principle in evolution, where extra resources are not invested in organs with specific purposes performed adequately.
Researchers have developed a practical calculator to predict the risk of developing epilepsy after cerebral venous thrombosis, a rare cause of stroke. The tool is based on factors already available in clinical routine and can help inform treatment decisions or support preventive medication for those at high risk.
Researchers at UVA Health System found that a hyperactive nervous system response can worsen C. difficile infections, leading to severe diarrhea, nausea, and colitis. Targeting the alpha 2 adrenergic receptor may provide a new therapeutic target for treating these deadly infections.
Researchers have discovered that comb jelly species can fuse after injury, rapidly synchronizing their muscle contractions and merging digestive tracts to share food. This process allows the fused individual to survive for at least three weeks.
A study from Goethe University Frankfurt reveals that venomous crustaceans, specifically remipede crabs in Mexican cenote caves, contain a variety of toxins with pharmacological potential. The xibalbines peptides effectively inhibit potassium channels and activate signaling pathways involved in pain sensitization.
Researchers have developed a novel platform for testing radiation therapy effects on brain cells, providing insights into how the brain reacts to cancer treatment. The study aims to improve treatment strategies by understanding the impact of radiation on neural circuits, ultimately leading to personalized care for patients.
The underwater endoscopic mucosal resection (UEMR) technique demonstrates promising outcomes in the treatment of gastrointestinal neuroendocrine tumors, particularly in rectal tumors. UEMR achieves complete histological resection at a lower cost with minimal requirement for advanced endoscopic skills.
Researchers engineered miniature linear and split-belt treadmills to study insect locomotion, gaining insights into proprioception's role in natural activities like walking. The study showed that flies can modify their steps to continue walking straight despite rotational perturbations.
A new algorithm, inspired by the nervous system's matchmaker, pairs drivers with riders in a way that maximizes everyone's happiness. The algorithm creates near-optimal pairings while preserving privacy, making it suitable for everyday applications.
A new UBC Okanagan study emphasizes the importance of identifying and managing neuropathic pain in high-performance athletes with spinal cord injuries. The research stresses the need for sports medicine clinicians and trainers to use standardized assessment tools, including symptom-based questionnaires, to better understand and communi...
Researchers at the University of Cincinnati are developing a new technology using magnetic nanoparticles to deliver medications directly to the inner ear, where hearing loss occurs. The goal is to create an effective and minimally invasive treatment option for various types of hearing loss.
A new study found that potassium ion channels in the Shaker family were present in single-cell organisms before the origin of the nervous system. This discovery challenges the conventional understanding of how these ion channels evolved alongside the nervous system.
A Chinese Medical Journal study developed an AI-based system to automate embryo selection and eliminate subjectivity in IVF. The system improved human embryo assessment and selection, achieving higher accuracy in embryo aneuploidy screening than experienced embryologists.
A study published in Neuron reveals that neurons are wired to connect seemingly unrelated concepts, enhancing the brain's ability to predict what we see based on past experiences. Visual experience influences the organisation of feedback projections, which store information about the world.
Viji Santhakumar, a UCR professor, has been awarded a $3.5 million NIH grant to study brain circuit function and its impact on memory formation and cognitive deficits in diseases like epilepsy and Alzheimer's disease.
Researchers at the Gwangju Institute of Science and Technology (GIST) have developed an innovative robotic rehabilitation system called SPINDLE to enhance the strength and dexterity of individuals with tremors. The study revealed significant benefits, including improved motor control, coordination, and neuroplasticity.
Scientists at Kyushu University created QDyeFinder, an AI pipeline that untangles the dense neuronal networks in the brain. The system uses a super-multicolor labeling protocol to tag neurons and then automatically identifies their structure by matching similar color combinations.
Two studies by Prof. Lucía Chávez Gutiérrez's team reveal the role of gamma-secretase inhibition and amyloid plaque composition in AD. Aβ42 fragments impede gamma-secretase function, while multimodal mass spectrometry imaging reveals diverse plaque compositions.
Research finds that Huntington’s disease damages microscopic blood vessels in the brain, affecting coordination between neuronal activity and oxygenation. The study uses non-invasive measurement techniques to monitor disease progression and evaluate potential treatments.
Researchers at the University of Malaga have developed an instruction manual to understand the operating limits of phantom motion, allowing for cost-effective and lighter haptic devices. The study found that individuals can perceive phantom sensation when a vibrating point travels at least 20% of the separation between actuators.
Researchers at Rice University have identified genes critical for enteric nervous system development using zebrafish embryos. Opioid signaling pathways are required for the formation of nerves in the gut, contradicting previous assumptions about their role in pain perception and addiction.
A new study assesses cognitive impairment over time in adults with essential tremor, finding a cumulative prevalence of 26.6% for mild cognitive impairment (MCI) and 18.5% for dementia. Early detection is crucial to slow further cognitive decline and improve quality of life.
Researchers discovered that mature oligodendrocytes, critical for brain function, can survive for up to 45 days after a fatal trauma, defying the classical programmed cell-death pathway. This finding opens new avenues for understanding and potentially preventing damage caused by aging and neurodegenerative diseases.
Researchers discovered how honeybees interpret dances that relay directions to food, even in complete darkness. By analyzing bee movements and antennae signals, scientists found a neural mechanism that combines sensory data from the two systems.
Researchers have solved the long-standing question of what triggers the alarm response in fish by identifying two distinct chemical signals: Daniol sulphate and Ostariopterin. These substances convey separate pieces of information that must be detected simultaneously to trigger a flight-or-freeze response.
A study by Fujita Health University researchers unveiled novel insights into the brain's processing of movement and sensation. The findings suggest that signals from motor cortices do not primarily modulate sensory responses in primary sensory cortices, but rather pathways from secondary somatosensory cortex (S2) and sensory thalamus (...
A new study reveals that Respiratory Syncytial Virus (RSV) can infect nerve cells, trigger inflammation, and cause nerve damage. RSV was previously thought to only infect the respiratory tract, but this finding suggests a potential link between the virus and neurological symptoms in children.
The latest issues of APA journals focus on improving clinical outcomes, exploring disparities in school-based support, and addressing civil commitment hearings. These studies aim to inform new interventions and improve mental health care.
Growth hormone influences regulation of anxiety via a specific group of neurons, according to researchers at the University of São Paulo. The study identified somatostatin-expressing neurons as key players in modulating GH's anxiolytic effect, with increased anxiety observed in mice lacking these neurons.
Researchers at Salk Institute uncover a mechanism for repairing damaged nerves during peripheral neuropathy, with protein Mitf playing a key role. The findings have the potential to inspire novel therapeutics that bolster repair function and heal peripheral neuropathy.
A study published by Vienna University of Technology analyzed the effects of extreme physical and mental stress on a rowing athlete's body. The research found that the variability in heart rate, sleep quality, and regeneration during sleep phases were closely related to the athlete's psychological condition.
Researchers have pinpointed the crucial changes in a membrane protein that allow Antarctic octopuses to function normally in freezing temperatures. By swapping specific amino acids, scientists discovered three key modifications that together enable the pump to work efficiently, allowing the octopus's nervous system to adapt and thrive.
Caribbean box jellyfish have demonstrated complex learning capabilities, including associative learning and memory formation, despite having only one thousand nerve cells. This discovery sheds new light on the evolutionary success of jellyfish and raises questions about the universality of advanced learning mechanisms in animals.
Researchers have identified a new cell type, ARG1+ microglia, involved in brain development and function during early postnatal stages. This discovery sheds light on the role of microglia in neural systems and their potential link to neurodevelopmental and neurodegenerative diseases such as Alzheimer's.
Researchers have discovered a group of nerve cells in the midbrain that can completely stop all forms of movement and slow down breathing and heart rate when stimulated. The study provides valuable insight into how the nervous system controls movement and may help understand Parkinson's disease.
Aneurysmal subarachnoid hemorrhage-related hydrocephalus is a complex syndrome that can lead to cognitive impairment and neurological damage. The new consensus guideline recommends standard-of-care approaches, including history review, head CT scans, and medications or surgical interventions to manage excessive intracranial pressure.
Researchers found that glial cells in the gastrointestinal tract respond to stress signals from the central nervous system, leading to inflammation and exacerbating IBD symptoms. Chronic stress can impair treatment efficiency for IBD patients using steroids.
Researchers have discovered that octopuses and cephalopods use RNA editing to rapidly respond to environmental temperature changes. By tweaking their protein function, these animals can acclimate to cold water, but not rapid changes. The study reveals a unique mechanism of genetic adaptation in these species.
A new study found an association between lower extremity spasticity and cryptorchidism treatment in boys with cerebral palsy. Boys with more severe spasticity were especially likely to have had the surgery, suggesting a potential link between affected muscles and testicle development.
Researchers analyzed 90 samples of raw pheasant dog food and found that 77% exceeded the maximum residue level for lead in animal feed. The mean lead concentration was 34 times higher than in human-consumed pheasant meat, posing health risks to dogs, especially puppies.
Scientists have created a detailed map of human spinal cord cell formation, shedding light on how injuries and diseases arise. The study's findings hold promise for developing new therapies for spinal cord injuries and diseases like ALS.
This study found that iron deficiency impairs neural differentiation, leading to reduced Pax6- and Sox2-positive neuronal precursor cells and Tuj1 fibers. Iron supplementation restores normal differentiation, suggesting ferrodifferentiation as a new therapeutic approach for neurological diseases.
A team of UCF College of Medicine researchers created a digital topographical map of the cardiac sympathetic neural network, controlling heart rate and 'fight-or-flight' response. The map will guide treatments like neuromodulation therapy for hypertension, sleep apnea, and heart failure.
A study found that monkeys with opposable thumbs were fooled by a sleight-of-hand trick, while those without were not. The French drop trick worked for capuchins and squirrel monkeys due to mirroring in their neural motor system.
Researchers identified over 1,000 genes with age-related methylation changes in human sperm. These changes are associated with increased offspring disease susceptibility for neurodevelopmental disorders. The study found no correlation between paternal BMI or semen quality and age-related methylation changes.
The study reveals that NEMO forms biomolecular condensates with ubiquitin chains to activate NF-κB signaling, facilitating rapid regulation of cellular responses. A pathogenic mutation in the NEMO gene inhibits this process, leading to a disease characterized by skin abnormalities and neurological symptoms.
Researchers have identified serine as a key contributor to peripheral neuropathy in diabetes, a condition that affects approximately half of people with type 1 or type 2 diabetes. Supplementing diabetic mice with serine alleviated neuropathy symptoms, suggesting a potential treatment option.
A new Dartmouth study uses a subjective approach to investigate how people perceive social interactions. The results show that the brain responds more strongly to information interpreted as social versus non-social, highlighting humans' tendency to see social connections.
A new laboratory test can measure levels of amyloid beta oligomers in blood samples, detecting toxic proteins up to years before cognitive impairment. The test, SOBA, has shown promising results in identifying individuals at risk or incubating Alzheimer's disease.
Research reveals mitochondria play crucial role in NF-κB signaling pathway regulation. Mitochondria assemble signaling platform at outer membrane, amplifying signal through large surface area.
A team of researchers identified a protein kinase substrate downstream of the dopamine signaling pathway regulating brain reward behavior. The study found that phosphorylation of potassium voltage-gated channel subfamily Q member 2 (KCNQ2) decreases its channel activity, increasing neuronal excitability and promoting reward behavior.
Researchers developed an epigenetic activator TTK21 to aid spinal cord regeneration in mice 12 weeks after severe injury. Treatment improved axon sprouting, sensory axon growth, and halted retraction of motor axons, leading to potential breakthroughs for human patients.
A new study reveals key clues about the form of the most ancestral nervous system and how it first evolved. Researchers found that neurons, possibly the most complicated cell type ever to evolve, share similar structures with comb jellies and other ancient animal lineages.
A new treatment has shown clinically meaningful effects on pain intensity and disability, with participants reporting improved quality of life and long-term benefits. The sensorimotor retraining approach alters how people think about their body in pain and normalizes communication between the back and brain.
Researchers developed a technology that uses surviving neurons to restore connection between brain and arm via specific stimulation pulses to the spinal cord. This allowed macaque monkeys with partial arm paralysis to improve precision, force, and range of movement in their arms.
The WVU program trains next generation of toxicologists to collect, analyze air samples from mining, fracking sites, using the university's Inhalation Facility. Students will work with preceptors from various fields to investigate health effects of inhaling toxicants.
A new study suggests that supplementing a diet with Ascidiacea, also known as sea squirts, reverses some main signs of aging in animal models. The researchers found that plasmalogens, vital to body processes, decrease with age and contribute to neurodegenerative diseases like Alzheimer's and Parkinson's.
A study by Tokyo University of Science researchers has demonstrated that a computationally-light model can simulate complex brain cell responses, including periodic and quasi-periodic responses. The Izhikevich neuron model was found to be capable of reproducing both types of responses at lower computational cost.
A novel bed net treated with chlorfenapyr has been shown to significantly reduce malaria infection in children, with a 43% decrease in the first year and 37% decrease in the second year. The study found that the bed net reduced clinical episodes of malaria by 44% over two years.