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Working to loosen the grip of severe mental illness

A Rutgers researcher discovered consistent brain patterns in the human brain, regardless of activity level, which could lead to a better understanding of serious mental health conditions. The study's findings suggest that the prefrontal cortex, involved in high-level thinking, may be altered in people with severe mental illness.

Synchronized brain waves enable rapid learning

Neurons in the prefrontal cortex and striatum synchronize their brain waves to form new communication circuits during category-learning, enabling rapid adaptation. This phenomenon likely precedes changes in synapses and underlies the human mind's flexibility.

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When good people do bad things

Researchers studied brain activity in a part of the brain involved in thinking about oneself and found that group dynamics can lead individuals to harm others outside their group. This is due to reduced medial prefrontal cortex activation when seeing moral statements, which correlates with increased likelihood of harming opponents.

How the brain pays attention

A new study reveals that the brain achieves focused attention on faces or other objects by synchronizing activity in the inferior frontal junction (IFJ) with specific brain regions. The IFJ coordinates with the fusiform face area (FFA) and parahippocampal place area (PPA), suggesting a parallel process involving different areas.

Study reveals workings of working memory

Researchers at Brown University discovered that working memory uses similar brain circuits to those involved in planning motion. They found that the caudate and dorsal anterior premotor cortex contribute to output gating, a crucial process for selecting from working memory. The study's findings provide insight into how the brain effici...

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Alcohol breaks brain connections needed to process social cues

Researchers found that alcohol intoxication reduces coupling between the amygdala and prefrontal cortex, impairing ability to accurately appraise environment and respond to social signals. This study provides insight into maladaptive behaviors seen in alcohol intoxication, including social disinhibition and aggression.

UCSB study reveals that overthinking can be detrimental to human performance

A new UCSB study published in the Journal of Neuroscience reveals that paying full attention and trying hard can impede performance. The study found that disrupting explicit memory resources, which are associated with conscious thought, can harm implicit memory processes, leading to poorer performance outcomes.

Stray prenatal gene network suspected in schizophrenia

Researchers found a link between spontaneous mutations and impaired neurogenesis in the prefrontal cortex of people with schizophrenia. The study suggests that genetic damage can disrupt brain development and lead to early signs of the illness, such as impaired executive functions.

Breaking habits before they start

Researchers at MIT found that blocking activity in the infralimbic cortex prevents rats from learning to run a maze on autopilot. The study suggests a new approach to treating disorders of repetitive behavior by targeting this brain region.

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Brain rewires itself after damage or injury, life scientists discover

Researchers found that parts of the prefrontal cortex take over when the hippocampus, a key learning and memory center, is disabled. The breakthrough discovery could potentially help develop new treatments for Alzheimer's disease, stroke, and other conditions involving brain damage.

Laser light zaps away cocaine addiction

Researchers have discovered that stimulating one part of the brain with laser light can wipe away addictive behavior in rats and turn non-addicted rats into compulsive cocaine seekers. The study suggests a new therapy using transcranial magnetic stimulation could be effective for humans, offering hope for treating cocaine addiction.

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How the brain copes with multi tasking alters with age

A new study found that the brain's pattern of blood flow in the prefrontal cortex alters with age during multitasking. Healthy older people had a higher and more sustained increase in oxygenated haemoglobin, indicating increased brain activity. This change is associated with normal aging and may impact dual-task performance.

First measurements made of key brain links

Researchers at Brown University have made the first direct measurements of cause-and-effect responses between the nonspecific thalamus and the prefrontal cortex. The study reveals that inhibitory neurons respond strongly to thalamic signals, leading to a pattern of excitation in the cortex that sustains attention and arousal over time.

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Snap judgments during speed dating

A study published in the Journal of Neuroscience identified two brain regions involved in making rapid judgments about potential partners. The paracingulate cortex and rostromedial prefrontal cortex are active when people consider physical attractiveness and individual compatibility, respectively.

In-sync brain waves hold memory of objects just seen

Researchers found that synchronized electrical signals between two key hubs in the brain's working memory circuit carry information about short-term visual memories. The study uses synchronized oscillations to distinguish between object identity and location, potentially overturning prevailing theory on how visual information is encoded.

How the brain controls our habits

A new study from MIT neuroscientists has found that the brain's prefrontal cortex has a small region responsible for controlling which habits are switched on at a given time. The researchers used optogenetics to inhibit this region, allowing them to break and form new habits in rats.

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Stress breaks loops that hold short-term memory together

Researchers at the University of Wisconsin-Madison found that stress breaks the neural loops that store and retrieve short-term information, leading to distractions and decreased performance. This discovery sheds light on how stress impairs working memory and may inform new treatment approaches for prefrontal cortex dysfunction.

Why are elderly duped? UI researchers explain why

Researchers identify ventromedial prefrontal cortex as key area controlling belief and doubt, explaining why elderly are more prone to scams. Damage to this region, particularly after age 60, can lead to increased credulity and decreased ability to distinguish misleading information.

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Brain imaging can predict how intelligent you are, study finds

Researchers found that global brain connectivity, specifically with the left lateral prefrontal cortex, explains 10% of individual differences in intelligence. The study suggests that this connection enables flexible hub-like function, monitoring and influencing other brain regions to accomplish tasks intelligently.

Study offers new clue on how brain processes visual information

Scientists have discovered an important clue on how the human brain filters out unimportant visual information and focuses on what's most useful. The study found that the prefrontal cortex is involved in both bottom-up and top-down attention, challenging traditional beliefs about separate areas of the brain controlling these processes.

This is your brain on pain

UTMB professor Volker Neugebauer is conducting a four-year, $1.36 million study on the relationship between pain and brain functions, particularly the amygdala and medial prefrontal cortex. The investigation aims to understand how abnormal pain input affects the brain's emotional response and decision-making processes.

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Long-term hormone treatment increases synapses in rat prefrontal cortex

A new study found that long-term treatment with estrogen and MPA increased levels of a protein marker for synapses in the prefrontal cortex of aged rats. This contradicts previous research on human hormone therapy, which linked hormone replacement to an increased risk of stroke and dementia.

Researchers use brain-injury data to map intelligence in the brain

Scientists have mapped the physical architecture of intelligence in the brain using a large pool of volunteer participants with brain injuries. The study identified specific brain regions and connections essential for general intelligence, planning, and executive function.

Scientists gain new insight into prefrontal cortex activity

Researchers at Wake Forest Baptist Medical Center used fMRI to study brain activity before and after monkeys learned new memory tasks. They found that a small group of neurons specialized in the new task were activated while retaining existing information.

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'Explorers,' who embrace the uncertainty of choices, use specific part of cortex

A study published in the journal Neuron reveals that individuals with strategic decision-making skills, known as 'explorers,' use a specific region of the prefrontal cortex to calculate relative uncertainty. This brain area is not active in non-explorers, suggesting a specialized cognitive process for making uncertain decisions.

Neural balls and strikes: Where categories live in the brain

Neural recordings reveal brain activity that encodes visual categories in the posterior parietal cortex, outperforming the prefrontal cortex. The study suggests that the parietal cortex is more involved in the categorization process, particularly for spatial and visual tasks.

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Depressed? Crossed wires in the brain

Researchers found decreased connectivity between emotional behavior regions and an increase in connection between the caudate and prefrontal cortex in depressed brains. This disruption may lead to sustained negative thoughts and difficulty updating working memory.

To ditch dessert, feed the brain

A study published by Yale University researchers found that when the brain's glucose levels drop, an area responsible for regulating emotions and impulses loses its ability to resist high-calorie food. This response is particularly pronounced in obese individuals, who exhibit a heightened desire for high-calorie foods.

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Yale researchers show how memory is lost -- and found

A new study published in Nature shows that the neural networks in the brains of middle-aged and elderly individuals have weaker connections and fire less robustly than in younger ones. However, the research suggests that this condition is reversible with the help of a medication called guanfacine.

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Advice vs. experience: Genes predict learning style

Researchers found that genetic variations can predict how persistently people will believe advice, even when it contradicts their experience. The study highlights the role of confirmation bias in decision-making, where people tend to distort experiences to align with pre-existing beliefs.

Which side of the brain rotates a mental picture?

A multidisciplinary team found that patients with tumors in the right parietal cortex struggled to process categorical spatial information, leading to errors in mental rotation tasks. The left prefrontal cortex was also affected, causing difficulties in setting up specific programs within the brain for task organization.

Tobacco smoking impacts teens' brains, UCLA study shows

UCLA researchers found a correlation between nicotine addiction and decreased prefrontal cortex activity in adolescent smokers. The study suggests that smoking can affect brain function, particularly during adolescence when the prefrontal cortex is still developing.

York U study pinpoints part of brain that suppresses instinct

A York University study has pinpointed the part of the brain that suppresses automatic behavior, such as looking away from a facial expression. The research found an increase in signal from the left inferior frontal cortex when participants were confronted with conflicting stimuli.

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Video gaming prepares brain for bigger tasks

Researchers found that experienced gamers showed increased activity in the prefrontal cortex, a region involved in complex tasks. The study suggests that video games can reorganize brain networks, offering hope for future research into Alzheimer's and other cognitive disorders.

Brain matter linked to introspective thoughts

A study published in Science has found that the anterior prefrontal cortex and white matter structure are associated with introspective ability. Researchers used MRI scans to analyze participants' brains and identified a correlation between gray matter volume and self-awareness, which could lead to better treatments for mental illness.

Why (smart) practice makes perfect

A study by neuroscientists at USC found that volunteers practicing a challenging arm movement with related tasks showed better retention of the skill. The prefrontal cortex was necessary for consolidating the memory, while constant practice focused on a single task did not retain the skill as well.

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Individual brain cells can ID both cars and cats

Researchers found that certain 'multitasking' neurons in monkeys' brains are best at making correct identifications in both car and animal categories. This ability to 'multitask' allows the brain to re-utilize neurons for different tasks, potentially leading to a better understanding of disorders like autism and schizophrenia.

The art of mindreading -- empathy or rational inference?

Researchers found that the brain's dorsolateral prefrontal cortex plays a key role in rational inference, but not emotions, in 'mindreading'. The study suggests that certain executive functions like cognitive flexibility may be important for processing what someone else is thinking.

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Empathy and violence have similar circuits in the brain

The study reveals that brain regions involved in empathy, such as the prefrontal cortex, overlap with those regulating aggression and violence. This suggests that promoting empathy may inhibit violent behavior by stimulating opposing neural circuits.