Articles tagged with Scars
A new compound, bis(phosphocholine)-hexane, has been designed to inhibit the effects of C-reactive protein (CRP), a protein that contributes significantly to heart attack damage. By blocking CRP's tissue-damaging effects, this potential drug may reduce mortality and scar size in patients who have experienced a heart attack.
A team of scientists from the University of Wisconsin-Madison reports a breakthrough in making human collagen in the lab, opening doors for medical applications and nanotechnology. The new discovery enables the creation of synthetic collagen that can be tailored for specific uses, including wound healing and implantable sensors.
A new study published in Catheterization and Cardiovascular Interventions found that drug-eluting stents reduce the incidence of restenosis, heart attacks, and death by fourfold compared to conventional stents. Medicated stents were effective in keeping vein grafts open without affecting other parts of the bypass.
Researchers at UCSD found that selectively inactivating the IKK beta gene in airway membrane-lining cells significantly reduces inflammation, mucus production, and scarring. This discovery suggests a potential targeted treatment for asthma sufferers.
Researchers have developed a method to modify collagen, allowing it to be used in new medical treatments such as preventing blood clots and scar tissue. The modified collagen can also be used to deliver drugs and control the shape of engineered tissue.
A Stanford study found that surgically closing a woman's peritoneum after a C-section significantly reduces the risk of abdominal adhesions. The research suggests that this long-held practice may not be necessary and could even offer benefits in terms of reducing post-operative pain.
A recent study found that workers exposed to Libby Vermiculite Ore have a significantly higher rate of pleural plaques, or scarring of the chest wall lining. The occurrence was as high as 44.1% in those with the largest exposure, and the risk increased with cumulative exposure.
Researchers have found that an experimental drug can effectively prevent much of the brain damage caused by traumatic injury. In a study using rat models, the drug was shown to reduce brain damage and improve cognitive and motor function. The breakthrough could potentially lead to new treatments for human traumatic brain injuries.
Scientists have identified two populations of immune cells in the liver that can cause scarring and break it down. This discovery may lead to future treatments for liver damage and cirrhosis, a condition that affects more women in the UK than cervical cancer.
Researchers have successfully regenerated the optic nerve in mice using a combination of techniques that prevent the formation of scar tissue. The study, led by Dr. Chen, shows promise for treating eye injuries and potentially improving outcomes for patients with glaucoma and spinal cord damage.
Researchers at Thomas Jefferson University have discovered a protein called CD36 that may play a key role in the development of diabetic kidney disease. The study found that CD36 is present in specific cells and can trigger self-directed cell death or apoptosis, leading to progressive kidney failure.
Researchers have identified two types of immune cells in the liver that can cause scarring or repair it. Understanding these cells may lead to new treatments for cirrhosis, a major cause of liver failure.
UC Riverside researchers found that cigarette smoke delays the formation of healing tissue and sets the stage for increased scarring. The study, led by Professor Manuela Martins-Green, used doses equivalent to 'first-hand' and 'second-hand' exposure in humans and mice, revealing the negative effects on fibroblasts' structure and function.
Researchers found that laser resurfacing can improve the look of sun-damaged skin and reduce acne scars with nonablative laser treatment. Increasing volume of botulinum exotoxin A at lower concentrations affects a larger area, making it suitable for treating larger areas like the forehead.
Burn victims may soon experience restored faces with a single operation, reducing pain and recovery time. Surgeons utilize innovative techniques to create thick skin flaps with unique blood supplies, eliminating huge scars and promoting emotional healing.
A new minimally invasive approach to upper lumbar fusion surgery has been developed, reducing the risk of complications and improving patient outcomes. The procedure, which involves a direct lateral approach through the psoas muscle, offers several practical advantages, including minimal muscular retraction and bleeding.
A Clemson bioengineer has created a method using laser beams to align cells in a pattern, simulating tissue environments on a small scale. This technology could lead to early detection of cancer, saving lives, by detecting cellular responses to light.
A small clinical trial showed that 22 out of 27 patients experienced improvement in symptoms such as weakness and pain after taking pentoxifylline for eight weeks. Researchers believe the drug may help reduce inflammation and improve quality of life for those with radiation fibrosis.
A UCR study found that exposure to second-hand smoke compromises the ability of fibroblasts to move towards damaged tissue, leading to abnormal healing and excessive scarring. The research team discovered that components of second-hand smoke alter the cells' cytoskeleton, increasing adhesive properties and reducing mobility.
Researchers at Scripps Research Institute have discovered a way to block fluid leakage that causes long-term tissue injury after a heart attack. A single dose of a compound can drastically reduce tissue injury and increase long-term survival following a heart attack.
Researchers infused decorin into spinal cord injury sites in rats, reducing inflammation and scar formation by 80-95%. This allowed nerve fibers to regrow across the injury site within four days.
Researchers found that adult stem cells can repair nerves, but the process is slow and scar tissue hinders healing. The study suggests that manipulating stem cells and growth factors could stimulate nerve regeneration.
Researchers found that nanotubes with tiny bumps cause less scar tissue and stimulate neurons to grow more fingerlike extensions, needed for brain activity regeneration. The findings suggest using a mixture of plastics and nanotubes could decrease scar tissue formation around electrodes.
A study at Duke University Medical Center found cardiac MRI can detect viable but damaged heart muscle, allowing for targeted treatment and improved outcomes. Researchers used cardiac MRI to visualize the beating heart, identifying areas of thinned muscle that could be saved with revascularization therapy.
Researchers tested mononuclear bone marrow cell transplant injections in patients with severe ischemic heart failure and found improved blood flow, reduced chest pain, and increased exercise capacity. Treated patients showed significant reductions in reversible defects and improvements in oxygen consumption and metabolic equivalents.
Scientists found certain fibroblasts can transform into myofibroblasts, leading to fibrosis, and lipofibroblasts, developing into fat cells that cause thyroid eye disease. This research may lead to new diagnostic tools and treatments for diseases like fibrosis and fatty tissue buildup.
A UCI biomedical engineer has received a $1.8 million grant to create viable lung tissue similar to that found in bronchial tubes, which will be injured to simulate asthma injuries. The goal is to better understand what causes scarring in the lungs of people with asthma and develop more effective treatments.
Researchers found that a protein called palladin is upregulated following traumatic injury to the central nervous system, forming a barrier that blocks neurons from recovering. Palladin appears to control astrocyte cell shape, leading to structural changes associated with injury.
A study of 74 eyes found that corneal ring segments significantly improved uncorrected and best-spectacle corrected visual acuity in keratoconus patients. The use of Intacs provides a less invasive solution, changing the curvature of the cornea without removing tissue.
Researchers have discovered that spherical crystals develop unique 'scar' defects to compensate for the curved surface, allowing them to pack in place. The findings, supported by experiments with water droplets and tiny beads, provide insights into how such structures form and persist in nature.
Children's Hospital Boston researchers have successfully regenerated zebrafish heart muscle after injury, regenerating cardiomyocytes with minimal scarring. This study provides new insights into the mechanisms of cardiac regeneration and may lead to novel therapeutic strategies for repairing human heart damage.
Researchers at Thomas Jefferson University Hospital have successfully treated chronic tendon problems like tennis elbow with ultrasound-guided needle therapy. The procedure involves injecting corticosteroids, smoothing out bone and tissue, and eliminating calcifications to promote healing.
Researchers successfully treated patients with scar tissue and impaired heart function after heart attacks by injecting their own bone marrow into the affected area. The treatment showed significant improvement in heart wall motion, persisting for at least 10 months in some patients.
A recent survey of 968 women aged 15-59 found that nearly 60% were told their pain is normal by their Ob/Gyn or a friend/family member. Chronic pelvic pain affects many lives, but often takes years to receive an accurate diagnosis.
Researchers have found a new avenue of HIV damage that affects the structure of CD4 T cells, making it impossible for them to function normally. This discovery may lead to improved disease staging and therapy, as therapies targeting inflammation and scar tissue accumulation could enhance current antiviral treatment.
Researchers at MIT have developed a biodegradable smart suture that can change shape in response to temperature changes, potentially solving medical implant challenges. The new material has shown promise for creating temporary shapes in confined spaces, such as those associated with minimally invasive surgery.
Researchers found that lung injuries among mice lacking CD44 receptors developed inflammation that persisted until the receptors were restored. The study suggests a vital link between the CD44 receptor and the body's healing process.
The University of Illinois Chicago has received a five-year, $7 million NIH grant to study the mechanisms of fertility and infertility. Researchers will investigate hormone regulation, immune response, and other factors contributing to endometriosis and infertility.
Researchers found that limiting scar tissue formation enables neurons to regrow and reconnect, leading to substantial recovery of function. This approach suggests potential for therapies to eliminate existing scar tissue at injury sites.
Scientists have identified a protein segment responsible for fibrous tissue growth leading to liver cirrhosis. They've developed a mutated version of the protein that blocks this process in mice, offering potential new hope for treating liver diseases.
Researchers have developed a new treatment option for atrial fibrillation using bipolar radiofrequency, which shows promising results in treating the condition. The procedure can be done without using the heart-lung machine and has been tested on sheep with successful outcomes, indicating it may be safe for human patients.
In a breakthrough study, researchers at The Wistar Institute demonstrated the remarkable regenerative powers of MRL mice in healing heart tissue without drugs or cell transfer. After two months, damaged heart tissue looked normal and functioned well.
A study by UCSD researchers reveals that chronic kidney rejection is caused by the recipient's own cells' normal reaction to a wound, specifically mesenchymal cells colonizing the transplant site. This finding opens up new possibilities for developing methods to block scar-causing cells and mitigate or prevent kidney rejection.
A new study from the University of Pittsburgh found that balloon mitral valvotomy yields similar long-term results to commissurotomy, a traditional surgical method. The procedure uses an inflated balloon to break scar tissue and improve valve function.