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Keeping skin healthy: New method provides molecular portrait of sebum production

Researchers developed a new method to map gene expression changes in sebocytes, providing insights into sebum production and its role in skin health. The study identifies key players in sebum production and suggests new ways to modulate it, with potential implications for acne, eczema, psoriasis, and infectious diseases.

SourceUniversität Leipzig·JournalJournal of Biological Chemistry·TypeExperimental study·DateJul 31, 2024

How the drug isotretinoin zaps acne

Researchers have discovered how isotretinoin, the most potent acne treatment, works by triggering cell death in sebaceous glands. The study found that agents targeting Neutrophil gelatinase-associated lipocalin may provide a new approach to treating acne.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateMar 3, 2008