Articles tagged with Tissue Structure
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
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Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers developed an innovative noninvasive technique that combines ultrasound and photoacoustic imaging to capture images of both tissue and blood vessels. The technology has the potential to address current gaps in medical imaging, providing faster and more comprehensive imaging at meaningful depths.
Researchers at Cold Spring Harbor Laboratory have created a tool called MaGNet to analyze the branching structure of mouse mammary glands. The system enables precise comparison of stained images and quantifies data with ease, allowing for earlier detection of breast cancer and investigation into hormonal changes and treatments.
A new method of 3D printing has been developed to mimic the complex strength and stretchiness found in real tissues like skin or other organs. This allows for more realistic training models for surgery, which could ultimately improve medical outcomes.
Researchers developed a new method for imaging enzyme activity in whole organs with high-resolution 3D mapping. This allowed them to visualize differences in aminopeptidase N activity and the effects of inhibitors in mouse kidneys. The study opens up an unbiased evaluation method for drug development.
Researchers at MIT have developed a new method to fabricate stretchable ceramics, glass, and metals using a double-network design. This material can stretch over four times its size without breaking, making it suitable for tear-resistant textiles and flexible semiconductors.
Researchers from ICTER have determined the 3D structure of RBP3, a key molecule in the visual cycle, shedding light on its role in retinal diseases such as diabetic retinopathy. The study reveals conformational changes upon binding to ligands, providing new insights into its functional mechanisms.
A study published in Brain reveals profound changes in the dopamine system in focal cortical dysplasia type 2, a congenital malformation associated with difficult-to-treat epilepsy. The findings suggest a disrupted dopaminergic system, which may contribute to the development of epileptic seizures and other symptoms.
A new plant tissue has been discovered in plants essential for seed formation, which can increase crop yields. The 'Kasahara Gateway' structure functions as a gateway and is regulated by a gene called AtBG_ppap.
Researchers have gained detailed insights into RBP3's structure and mechanism of action, shedding light on its role in protecting the retina from diseases. The study suggests potential therapies to slow or stop retinal degeneration, including RP and myopia.
A new imaging technology has been developed that combines super-resolution imaging with artificial intelligence to reveal subcellular structures and dynamics in living cells. This breakthrough enables scientists to better understand the root causes of diseases, leading to improved treatments.
Researchers developed a 3D-printed hydrogel from cow meniscus tissue, customized to individual patient needs, offering a more precise solution for meniscus repairs. The treatment aims to outperform current methods, which often result in poor healing.
A study by Medical University of Vienna reveals high blood pressure can cause abnormalities in podocytes, specialized cells in the renal filter, before other conditions like diabetes. Early detection and treatment are crucial to prevent kidney damage.
Researchers developed a standardized playbook for multi-material projection-based bioprinting, achieving high-fidelity printing of composite bioink structures. The system uses a synergistic cleaning strategy to minimize cross-contamination and variability in photopolymerization characteristics.
A team of scientists has successfully developed a novel platform for diabetes treatment utilizing bioink derived from pancreatic tissue and 3D bioprinting technology. The HICA-V platform replicates the structure and function of the human endocrine pancreas, supporting islet maturation and functional enhancement.
Researchers argue that the current paradigm of cancer as a genetic disease is unproductive due to inconsistencies in sequencing data. Alternative paradigms considering non-genetic processes, such as disruptions in gene regulatory networks and tissue organization, are proposed to guide future experiments.
Researchers have discovered how severe COVID-19 can destroy immune cells' ability to repair the lungs, leading to lingering effects of long COVID. By enhancing damaged organelles using a FDA-approved drug, they found improved lung healing and reduced inflammation.
The Damon Runyon Cancer Research Foundation has named 13 new Fellows, awarding them $300,000 each to investigate cancer causes and mechanisms. Five recipients of the Dale F. Frey Award for Breakthrough Scientists will also receive an additional $100,000 investment to catapult their research careers.
Researchers at Weill Cornell Medicine have discovered a precise mechanism by which an ion channel regulates its function, providing insights into fundamental biology and potential new treatments for diseases. The study identified a 'ball-and-chain' structure that plugs the channel, opening the way to modulate ion channel activity.
Researchers developed Janus-type supramolecules that form stable ribbon-type assemblies, guiding the arrangement of ion channels across lipid membranes. The supramolecular channels mediate efficient and selective K+ transport, disrupting cancer cell balance and inducing apoptosis.
The new μETF method simplifies fabrication of flexible 3D microelectrode arrays for neural applications. It reduces stimulation thresholds by 1.7 times and improves spatial resolution compared to traditional flat electrodes. The technology has potential in brain-computer interfaces, wearable electronics, and lab-on-a-chip systems.
An international research team developed a user-friendly software method called Segment Anything for Microscopy, which can precisely segment images of tissues, cells, and similar structures. The new model improved performance for cell segmentation, enabling researchers to automate tasks that previously took weeks of manual effort.
A study of Viking skulls using CT scans reveals a range of diseases including sinus and ear infections, osteoarthritis, and dental diseases. The results provide greater understanding of the health and wellbeing of the Viking population.
Researchers have created a new imaging technique that uses the nanostructures found on butterfly wings to analyze cancerous tissues, providing a simpler and more accessible tool for cancer diagnosis. The method has shown comparable results to conventional staining methods and advanced imaging techniques, offering a stain-free alternative.
Researchers developed a durable de-icing surface inspired by human skin's layered structure, achieving exceptional performance with low ice adhesion strength. The surface design creates extensive wrinkling at the ice-substrate interface, allowing ice to shed under its own weight without external energy inputs.
A new laparoscopic imaging technique uses stereo depth estimation and speckle-illumination SFDI to accurately map the optical properties of biological tissue. The device provides detailed optical property maps, enabling surgeons to identify critical tumor margins and improve clinical outcomes.
Researchers developed mini biohybrid rays using cardiomyocytes and rubber, demonstrating improved swimming efficiencies approximately two times greater than previous biomimetic designs. The application of machine-learning directed optimization enabled an efficient search for high-performance design configurations.
Researchers used cryo-electron microscopy to determine the atomic structure of collagen assemblies with an unexpected right-handed superhelical twist. This discovery could reshape biomedical research by revealing greater structural diversity in collagen.
Researchers explore structural and functional characteristics of Russula vinosa Lindblad polysaccharides, finding potential applications in pharmaceuticals and functional foods. The study reveals that structural differences between polysaccharides influence immunomodulatory activities.
Researchers found that ornamental never never plants can store water for up to 45 days, maintaining photosynthetic activity and chloroplast structure unchanged. This helps them adapt to drought conditions, a challenge for many crops.
Researchers at La Jolla Institute for Immunology discovered that tissue-resident memory CD8 T cells rise up to fight infections in the small intestine, using spatial transcriptomics technology. These immune cells are split between villi and crypts, with progenitor-like cells replenishing effector T cells.
Researchers at KAIST developed CamBio, a biotemplating method utilizing specific intracellular proteins to create functional nanostructures with high tunability. The method enables the selective synthesis of nanostructures from biological samples, showing improved performance in surface-enhanced Raman spectroscopy substrate detection.
Researchers found that octopus arms have a segmented nervous system, giving them precise control across all eight arms and hundreds of suckers. This spatial map, called 'suckeroptopy,' facilitates complex sensory-motor ability, allowing the octopuses to taste, smell, and explore their environment.
The KAIST research team developed a highly stretchable microelectrode array to monitor organoids' functions, enabling real-time analysis of their states. The technology showed promise in high-throughput drug screening applications, revealing changes in signal characteristics according to size and identifying potential drug interactions.
A USC Stem Cell study found that the mammalian outer ear evolved from cartilaginous gills in fishes and marine invertebrates. The research used gene control elements to show a connection between gill and ear development.
Researchers from The Hebrew University of Jerusalem have pioneered the use of metamaterials to replicate the texture and structure of traditional meat. Their novel approach enables the mass production of whole cuts of meat at a cost of $9 per kilogram, making sustainable protein alternatives more accessible.
Researchers at Texas A&M University have uncovered a mechanism behind cancer progression: the stiffening of tumor cell's environment. This spreading causes increased cell proliferation and tumor growth.
Researchers developed an ultra-compact transparent ultrasonic transducer for simultaneous high-resolution ultrasound and photoacoustic imaging. This technology improves diagnostic sensitivity by providing detailed information about tissue vasculature, thereby enhancing early cancer detection.
Researchers developed a new approach to engineer tissue structures across multiple scales, from small cells to large organs. They used gallium as a molding material, allowing them to create complex vascular and interwoven networks that mimic natural biological systems.
Researchers have developed a new X-ray technique called XL-DOT that visualizes crystal grains, grain boundaries, and defects in materials, enabling previously inaccessible insights into functional materials. The technique uses polarized X-rays to probe the orientation of structural domains in three dimensions.
Scientists discover that pregnant and nursing women's intestines undergo significant changes, doubling their surface area and reorganizing villi structure. This adaptation is crucial for the health of babies and may have long-term metabolic consequences.
A new study reveals that the arm-like structures of mammalian brain cells, known as axons, are actually pear-shaped and not cylindrical tubes. The research team used high-pressure freezing electron microscopy to visualize the axons' structure, showing that they have a bubbly, pearl-like shape.
Researchers discovered that heart cockle shells have translucent areas with hair-thin strands that deliver specific wavelengths of light into the bivalves' tissues. This natural system filters out bad wavelengths and channels in optimal wavelengths for photosynthesis, benefiting the clams' symbiotic algae.
Researchers identify caveolae's role in protecting adipocytes from rupture and inflammation; this discovery opens new avenues for treating metabolic diseases like obesity. The study highlights the importance of the caveolin-1 protein in maintaining cellular integrity.
Researchers at UVA have developed a new polymer design that decouples stiffness and stretchability, allowing materials to be both strong and flexible. The 'foldable bottlebrush polymer networks' can store extra length within their structure, enabling them to elongate up to 40 times more than standard polymers without weakening.
Researchers sequenced tissue and plasma samples from patients with conventional CRAs to identify genetic alterations. They found that a small proportion of samples successfully detected tissue-origin variants within matched cfDNA. The study also explored the genomic characteristics and progression of cancer from CRA to CRC-I, highlight...
Researchers create system to manipulate cell behavior using 'crowd control' technique, enabling predictable patterns and structures. Cell density plays key role in guiding cellular development, offering potential for medical applications such as tissue engineering and organ regeneration.
A new pterosaur species reveals key transitional changes between early and later groups, shedding light on the evolution of these flying reptiles. The complete specimen helps bridge the gap in understanding how they transformed from smaller to larger sizes.
A new mathematical model of prostate cancer has been developed, revealing key findings on genetic changes and tumour growth. The study shows that strong genetic changes are necessary for aggressive tumours to develop early in the course of tumour development.
A new PACT system offers rapid imaging of living organisms, enabling the tracking of whole-body dynamics and disease progression. The system achieves spatial resolution of approximately 212 micrometers and enables the visualization of oxygen saturation across complex biological systems.
A team of biomedical engineers from the University of Melbourne has developed a groundbreaking 3D printing system that can fabricate complex human tissues in just seconds. This technology significantly improves the potential to predict and develop new pharmaceutical therapies, reducing the need for animal testing.
A new type of cationic epoxy photoresist exhibits greater sensitivity to two-photon laser exposure, enabling fast writing speeds and fine features. The material was developed by a research team led by Professor Cuifang Kuang, who achieved lithography speeds of 100 mm/s and resolution of 170 nm.
Researchers have developed a production method for a nanofibrous cellulose matrix, replacing non-renewable industrial materials with environmentally friendly alternatives. The new method has potential biomedical applications due to its biocompatibility properties.
Collymer is a regenerative collagen polymeric biomaterial designed for various medical applications. It can be engineered into materials with different shapes and properties to address unmet clinical needs in wound care, tissue reconstruction, aesthetics, orthopedics, and therapeutic cell delivery.
Aston University researcher has developed a new technique harnessing Orbital Angular Momentum (OAM) light to improve imaging and data transmission through skin and biological tissues. The OAM-based approach shows unmatched sensitivity and accuracy, paving the way for non-invasive medical diagnostics and imaging.
A team from UNIGE analyzed the formation of grooves in dog noses using 3D imaging and computer simulations. They found that differential growth of skin tissue layers leads to the formation of domes, supported by blood vessels.
A team of scientists has created a comprehensive atlas of early mammalian morphogenesis, revealing that individual events such as cell divisions and movements are highly chaotic. However, the embryos as a whole end up looking very similar to one another, with physical laws driving them to form a specific morphology shared among mammals.
Researchers at Texas A&M University have developed a method to recharge cellular mitochondria using nanotechnology, potentially extending healthy lifespans and improving outcomes for patients with age-related diseases. The molybdenum disulfide nanoparticles stimulate mitochondrial regeneration, helping cells generate more energy.
A University of Virginia engineer developed a workflow to combine advanced imaging technologies for improved understanding of porous bone, which could inform disease detection. The method allows for three-dimensional rendering of bone structure across various length scales.
A research team has successfully recreated wrinkle structures in biological tissue in vitro, revealing the mechanisms behind their formation. The study found that compressive forces and dehydration play a crucial role in wrinkle formation, mirroring aging skin effects.
Researchers have developed a new technique to study anisotropic materials, capturing full complexity of light behavior in these materials. The method revealed detailed insights into how light scatters differently along various directions within materials, allowing retrieval of scattering tensor coefficients.