Articles tagged with Tissue Structure
A Rice University researcher has developed a natural extracellular matrix from adipose cells that supports the growth of living cells into tissues. The substance, called Adipogel, has been proven effective for growing liver cells and may be used to repair damaged organs in the future.
The ATS and ERS have issued guidelines for quantitatively assessing lung structure using advanced imaging techniques. These guidelines promote the accuracy and comparability of studies, facilitating interdisciplinary collaboration.
The Journal of Histochemistry & Cytochemistry will be published by SAGE beginning with volume 59 in 2011. The journal focuses on significant advances in visual techniques providing biochemical and molecular information about cells, tissues, and organs.
Researchers identified a molecule, MMP2, that controls fibroblast growth factor (FGF) signaling in fruit flies, allowing them to study the process of tissue invasion. This finding may provide new insights into how cancer cells spread and could lead to the development of new treatments.
Researchers created super-strong collagen with improved stability, which could treat conditions like arthritis by mimicking natural collagen. The new collagen holds together at high temperatures and has a similar three-dimensional structure to natural collagen.
Cyclone Edzani, a powerful Category 4 storm, is generating extreme waves and super swells over the open ocean. The storm's eye was visible in a NASA satellite image, and forecasters predict it will continue moving southwesterly, entering cooler waters by early next week and weakening.
Scientists develop a laboratory chip with nanoscopic features that enables heart cells to grow and function like natural heart muscle. The 'nanosense' allows cells to collect instructions from the physical patterns on the chip, guiding their behavior.
A groundbreaking face and upper-jaw transplant has successfully integrated donor tissue with no long-term rejection, enabling the recipient to regain senses of smell and taste. The procedure, performed on a patient with extensive damage from postoperative scarring and blood vessel depletion, demonstrates the feasibility of facial trans...
Researchers at Wake Forest University Baptist Medical Center have successfully grown replacement penile erectile tissue in rabbits, enabling normal sexual function and offspring production. The engineered tissue has the potential to benefit patients with congenital abnormalities, penile cancer, and some cases of erectile dysfunction.
Typhoon Parma is expected to make landfall in the northeastern province of Isabela, causing heavy rains and mudslides. The storm's powerful winds will also slam Luzon with rain over the next two days, exacerbating existing flooded conditions.
Researchers in the UK create a surface with hydrophobic and hydrophilic sections to move plastic nanoparticles quickly and in specific directions. This breakthrough could lead to advancements in treating diseases by coaxing cells to grow and heal in desired ways.
Cells in developing tissue consider their history of signaling exposure to determine location, challenging the widely held hypothesis that morphogens are the primary source of positional information. Researchers found that cells require a 'memory' of past exposure to morphogen signals to adopt specific gene expression patterns.
Researchers are designing liver mimics that can eventually form the basis for extracorporeal liver-assist devices. The primary research goal is to assemble 3D cellular structures that mimic the liver, capturing precise spacing between different cell types.
A team of researchers will conduct the largest earthquake simulation on a wooden structure, exposing a seven-story building to forces of an ancient earthquake. The goal is to develop new design approaches for stronger and safer wooden buildings.
Researchers have created a tiny micron-sized device that allows them to measure and manipulate cellular forces as cells reorganize into tissues. This discovery has significant implications for the study of tissue mechanics and its role in coordinating cell signaling, gene expression, and behavior.
Researchers at Harvard University have developed a framework for studying the arrangement of tissue networks created by cell division across various organisms. The model reveals that regular features in tissues can indicate properties about the cell division mechanism itself.
Researchers found that a specific region of the brain, orbitofrontal cortex and ventral striatum, is associated with higher levels of social reward dependence and emotional warmth. This discovery may help understand why some people are more sociable than others.
Kristen Billiar, a WPI biomedical engineering professor, has been awarded a Fulbright Scholarship to work on nanoscale scaffolds for tissue engineering at the National University of Ireland Galway. He aims to develop novel techniques to probe relationships between scaffold structure and mechanical functioning.
Researchers at Brown University have successfully grown and assembled living microtissues into complex three-dimensional structures, advancing tissue engineering. The breakthrough could eventually reduce the need for certain kinds of animal research, with implications for basic cell biology, drug discovery, and tissue research.
Researchers have successfully grown human-like tissue in the lab using umbilical cord blood stem cells to create functional heart valves. The tissue-engineered valves exhibited properties similar to those of natural human valves, including collagen and elastin production.
The journal features two articles with detailed instructions for setting up experimental culture systems. These methods allow researchers to study and manipulate developing cells and tissues in the laboratory, enabling the identification of neural progenitor cells and the analysis of cell migration between organs during development.
The AAAS study found 626 points of destruction affecting civilians in 24 villages near Tskhinvali, with significant fire damage and evidence of military activity. The analysis contradicts Russia's claim that Georgian troops inflicted most of the damage.
Researchers have developed a new three-dimensional computer model that reveals surface tension plays a crucial role in cell sorting. The study found that when minority cells make up at least 25% of the mix, they are more likely to be in direct contact with other minority cells, enhancing the surface tension effect and allowing it to dr...
A new design for slope marine docks aims to minimize damage from strong waves, enabling them to withstand increased swells without breaking. This innovative solution, developed by Spanish engineers, has the potential to significantly reduce costs associated with construction, maintenance, and upkeep of maritime structures.
Researchers developed a novel 3-D screening method for analyzing cell-material interactions, cutting initial search times in half. The technique enables rapid assessment of biomaterials' biocompatibility and properties, with applications in tissue and organ repair.
Scientists at Argonne's Advanced Photon Source have mapped the molecular structure of collagen fibrils, revealing how they bind to enzymes that regulate growth and development. This breakthrough could lead to the creation of inhibitors to prevent cancerous tumors or rheumatoid arthritis.
Erin Lavik, an assistant professor of biomedical engineering at Yale University, was recognized as one of the Connecticut Technology Council's 2008 Women of Innovation. Her research focuses on developing new therapeutic approaches for spinal cord injury and retinal degeneration.
Researchers at Columbia University have developed a novel porous structure that facilitates the delivery of bioactive cues, accelerating host tissue integration and new bone growth. This controlled-release approach reduces the need for high drug doses, offering a promising solution for orthopedic and dental implants.
Researchers from EMBL discovered that proteins regulating iron metabolism play a vital role in ensuring nutrient and water absorption in the intestine. The study found that mice lacking these proteins suffer from weight loss, dehydration, and impaired nutrient absorption.
Researchers have developed a new method to monitor peripheral neuropathy by analyzing tiny structures in the skin called Meissner corpuscles. This non-invasive technique allows doctors to detect nerve damage and track its progression, providing a valuable tool for early diagnosis and treatment.
Engineers Dr. Colin P. Ratcliffe and Dr. Roger M. Crane developed SIDER, a nondestructive testing method for detecting flaws in composite materials. The method involves tapping the material with a specialized 'hammer' and recording data from mechanical vibrations.
Researchers created a molecular map of aging in mice by analyzing gene expression changes in 16 different tissues. The study found that different tissues exhibit distinct patterns of aging, suggesting three separate clocks for aging, and that some pathways are shared with human aging.
A team of researchers from the University of Reading has developed a powerful X-ray beam technique to study the structure of amniotic membranes and their rupture. The findings reveal that the loss of a molecular lattice-like arrangement governs the timing of membrane rupture, paving the way for therapies to prevent premature birth.
A University of Missouri-Columbia research team has developed a biology-based process for printing organ tissue structures, maintaining cell properties and allowing nature to take over. The breakthrough enables the creation of functional tissue structures without needing to control cell location or function.
Researchers studying elevated homocysteine levels on vision found that it disrupts the retina's blood vessel network. Elevated homocysteine levels can also interfere with protein synthesis, collagen structure, and folate transport, leading to retinal damage and vision loss.
Researchers developed a silk-based scaffold, SeriACL Graft, to regenerate or re-grow anterior cruciate ligament (ACL) tissue in goats. The study demonstrated the safety and efficacy of the device in promoting ACL regeneration, with 95% of animals returning to normal gait by 6 months.
Researchers are conducting phase I trials comparing slow-freezing techniques to a rapid method of cryopreservation that transforms tissues into glass-like structures. The goal is to make human eggs, ovarian tissue, blood vessels, and whole organs available when needed.
Researchers mapped the stiffness of bovine shin bone using a molecular force probe, revealing non-uniformity in bone's mechanical properties within a single region. The study's findings could lead to improved diagnoses and treatments of bone diseases, as well as the development of new materials with improved toughness.
Researchers at NewYork-Presbyterian/Weill Cornell developed a simple and effective technique to reconstruct key anatomical structures that ensure continence. The procedure added only two to five minutes to standard robotic prostatectomy and achieved a 95% continence rate among patients 16 weeks after their surgeries.
Xinqiao Jia is awarded a National Science Foundation Faculty Early Career Development Award for her work on developing strong, yet soft and flexible biomaterials for engineering damaged tissues. Her goal is to create hybrid materials that can respond rapidly and reversibly to mechanical forces.
Researchers at Argonne National Laboratory have developed flexible electronic structures that can bend, expand, and manipulate devices, paving the way for applications in sensors and artificial muscles. These structures were created by forming single-crystalline semiconductor nanoribbons in stretchable geometrical configurations.
Researchers at the University of Michigan have made significant progress in cardiac tissue engineering, with promising results in growing pulsing heart muscle and tri-leaflet valves. However, challenges such as determining optimal cell types and finding effective methods to grow viable tissue still need to be addressed.
Bissell's work revolutionized understanding of cancer biology, revealing that the interaction between cells and extracellular matrix influences cell proliferation, survival, and differentiation. Her research has brought closer to a complete understanding of how living cells function in three-dimensional tissue.
A new study suggests that aging has evolved as a strategy to allow family lines to persist longer. By concentrating cellular damage in one individual, the rest of the line can continue to reproduce without harm. This asymmetric reproduction method may be favored by evolution due to its potential to increase longevity.
Researchers found that hyaluronic acid injections induce type 1 collagen production in photo-damaged skin, suggesting potential benefits for facial skin as well. This mechanism may involve mechanical stretching of fibroblasts, stimulating growth factors and inhibiting collagen breakdown.
A new medical technique using microsecond electrical pulses has been shown to create permanent nanoscale holes in target cell membranes without harming surrounding tissue. This technique, called irreversible electroporation (IRE), has the potential to revolutionize minimally invasive surgical treatments for tumors.
A new mathematical model explains the distinctive structure of collagen, a material key to healthy human bone, muscles, and tissues. The model shows collagen's structure from the atomic to the tissue scale, providing insights into its high extensibility and strength.
Researchers at Max Planck Institute found that bone stretches more than its fibers and mineral composition, allowing it to sustain large strains without breaking. The hierarchical structure of bone leads to a hierarchical deformation, with soft layers absorbing most of the strain, protecting the mineral phase from excessive loads.
Researchers at Thomas Jefferson University have found a nanoparticle that can protect normal tissue from radiation damage as effectively as standard drugs. The nanoparticle, called DF-1, acts like an oxygen sink, binding to dangerous oxygen radicals and reducing their production.
Researchers at Max Planck Institute and ESRF study bone deformation using X-rays, revealing a hierarchical structure that allows bones to sustain large strains without breaking. The findings provide new insight into the design principles behind healthy bone fracture resistance.
Researchers found a reduction in total hippocampus volume among adult male veterans with a history of heavy drinking, suggesting injury to the brain structure. The study's results may explain some memory impairment and cognitive deficits observed in chronic alcoholics.
Researchers have made a significant breakthrough in cryopreservation by discovering a way to slow down the formation of ice crystals in cells. This discovery, published in the Journal of Physical Chemistry B, could pave the way for preserving organs and tissues without damage.
Researchers are studying salamanders and MRL mice to identify the types of cells, molecular signals, genes, and cellular scaffolding required for regenerative cell growth. They hope to develop a blueprint for regenerative growth, which could help overcome the formation of scar tissue in humans.
Researchers used gold beads to visualize slow phenomena in the eye, such as growth and fast eye movement. The study showed that three-quarters of the implanted beads remained stable over six months.
Researchers at MIT developed a tool to selectively irradiate blood vessels to study radiation damage. This technique has the potential to reduce side effects for cancer patients treated with radiation therapy.
Researchers at Forsyth Institute discover that gap junctions play a crucial role in planarian regeneration by facilitating long-range signaling. By closing down gap junctions, the team found that cells can adopt radically different fates, leading to the growth of complex structures.
Scientists generate 3D image of coproporphyrinogen oxidase (CPO) at atomic level, shedding light on mutations causing hereditary coproporphyria. The study provides insights into the heme biosynthesis pathway and its role in rare diseases.
Researchers discovered the structure of miniature motors in muscles and found out how they are switched off. By studying tarantula striated muscle, scientists created a detailed model of the myosin heads and their interactions with actin filaments.
Researchers have developed a novel inhibitor, SB-3CT, that protects against brain damage in mice undergoing a stroke. The treatment reduces brain damage to 30% and preserves neurological function, offering potential for new stroke treatments.
The USC High-resolution Ultrasonic Transmission Tomography (HUTT) system offers superior 3D images of soft tissue, outperforming existing commercial X-ray, ultrasound, or MRI units. The technology uses multi-band analysis with sub-millimeter ultrasonic transducers to create detailed images with improved resolution and precision.