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A DEDD cert to support embryo development

A recent study has identified DEDD protein as essential for the formation of a functional decidua in mice. Defective DEDD function may be responsible for female infertility. The researchers suggest further investigation into the relationship between DEDD dysfunction and infertility in women.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateDec 6, 2010

Scientists find 'redesigned hammer' that forged evolution of pregnancy in mammals

Researchers at Yale University identified a key regulatory link in the evolution of pregnancy involving the altered function of HoxA-11 protein. This finding revolutionizes our understanding of how pregnancy evolved in mammals, highlighting a crucial genetic switch that tempered the immune system and allowed for internal development.

SourceYale University·JournalProceedings of the National Academy of Sciences·DateSep 18, 2008

Absence of critical protein linked to infertility

The study reveals that the transcription factor protein C/EBPb is necessary for decidualization and successful pregnancy in mice. In humans, its presence may become a vital gene marker for predicting uterine readiness for implantation. This breakthrough could potentially alleviate shortcomings in in vitro fertilization.

SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalProceedings of the National Academy of Sciences·DateJan 16, 2006

Risks from labor after prior cesarean delivery low, study reports

A recent study published in the New England Journal of Medicine found that vaginal birth after a prior cesarean delivery poses relatively low risks. However, the study also revealed that women attempting vaginal birth after a cesarean delivery may face increased complications such as uterine rupture and infant brain oxygenation issues.