Research on weight loss and its health effects. Covers GLP-1 injections, companion digital programs, pregnancy guidelines, and asthma benefits.
A new study found that dieters who eat in response to emotions, rather than social situations, tend to lose less weight and experience more weight regain. Emotional eating was associated with lower weight loss and higher likelihood of regaining weight in successful losers.
A team of Australian researchers has developed a novel treatment for obesity and extreme weight loss in late-stage cancer patients. By targeting the MIC-1 molecule, which sends a 'don't eat' signal to the brain, they hope to prevent this condition and improve chances of recovery.
A five-year study of electronic health records from 15 VA hospitals found significant variations in high blood pressure return-to-normal rates between winter and summer. The average difference was 7.76 percent, suggesting that seasonal factors such as weight gain and exercise may influence blood pressure.
A Mayo Clinic study found that modest weight gain in lean, healthy young adults impairs blood vessel function, but shedding the weight restores proper functioning. Visceral fat is a key predictor of this disorder, also known as endothelial dysfunction, which can lead to heart attacks and strokes.
A study found that supervised exercise programs resulted in varying weight loss outcomes due to compensatory responses such as increased hunger and food intake. The research suggests that individual variability plays a crucial role in weight management, highlighting the need for tailored approaches to address differences in physiologic...
Contrave significantly reduced food intake in both lean and obese mice by targeting the ventral tegmental area, a key region of the reward pathway. The combination of bupropion and naltrexone resulted in a 94% reduction of food intake in obese mice, demonstrating potential for effective weight loss treatment.
High-risk morbidly obese patients who lose 5-10% of their excess body weight before undergoing gastric bypass surgery have shorter hospital stays and more rapid postoperative weight loss. Preoperative weight loss also decreases surgical complications, reducing hospital stay length.
A recent editorial highlights the need for further research on bariatric surgery's risks and outcomes to convince non-believers of its benefits for morbidly obese patients. Studies suggest that routine upper GI tests may not be necessary, and complications can have devastating consequences if left untreated.
Researchers found that behavioral skills maintenance and social facilitation interventions improved weight loss maintenance in childhood overweight population, with some evidence for sustained long-term efficacy among more socially adept children. The studies demonstrated the importance of continued treatment contact to improve weight ...
Researchers found that 50% of overweight, hypertensive adults achieved normal body weight and blood pressure after six months of treatment with a reduced-calorie diet. This suggests that blood pressure may be secondary to body weight rather than essential hypertension in these patients.
Professor Glenn Gaesser analyzes peer-reviewed research, debunking the notion that high-carb diets lead to weight gain. He finds that people consuming high-carb diets tend to be slimmer and healthier than those on low-carb diets. Gaesser attributes this to a higher quality of diet, including more fiber-rich foods.
A long-term study published in The New England Journal of Medicine reveals that bariatric surgery reduces mortality in severely obese patients by 29%. The researchers found that the actual weight loss is less important than the surgery itself in reducing risk, opening up new possibilities for treatment development.
A new study published in the Journal of Human Lactation has found that exclusively breastfed newborns tend to lose less weight than formula-fed infants, which may be at risk of early overfeeding. Supplemented breastfed infants had similar weight loss patterns to exclusively breastfed newborns.
A study found that women with dementia start losing weight up to 20 years before diagnosis, due to reduced appetite and motivation. Men with dementia do not experience significant weight loss in the years leading up to diagnosis.
A survey of UK nurses found that many primary care surgeries lack effective obesity support, with only 14% having a well-developed programme. Despite this, 89% recognize the need for more support and 88% believe health risks are not overstated.
A recent study published in the International Journal of Food Sciences and Nutrition found that a low-fat, high-carbohydrate diet with sucrose achieved significant weight loss and improved health outcomes for overweight women. The study suggests that excluding sucrose from a diet may not be necessary to achieve weight reduction.
A new study published in Annals of Internal Medicine found that dietary counseling results in significant weight loss, with 10-15 pounds lost after one year. Moderate weight loss reduces diabetes, cholesterol, and blood pressure risk, making a lasting impact on overall health.
Researchers found that using portion-control dishes led to an average weight loss of 1.8% among participants, compared to 0.1% for those receiving usual care. Additionally, more patients using the dishes experienced a decrease in diabetes medication use after six months.
A study led by Stanford surgeon John Morton found that patients who undergo gastric bypass surgery are more sensitive to alcohol, reaching higher breath-alcohol levels and taking longer to sober. This altered metabolism may contribute to an increased risk of addiction.
A study by the University of Kentucky found that OTC strength orlistat (Alli) resulted in significant weight loss, with participants losing approximately 7-15 pounds over four months. The study also demonstrated a reduction in LDL-cholesterol and associated heart health benefits.
New study links unexplained late-life weight loss with Alzheimer's disease severity, suggesting it may be an early predictor. Researchers found that weight loss preceding dementia by more than 10 years is associated with the severity of brain changes in Alzheimer's patients.
A year-long clinical trial shows that diets focusing on foods with low calorie density can lead to significant weight loss and improved hunger control. The study found that women who added water-rich foods to their diets lost more weight during the first six months compared to those following a reduced-fat diet.
The 'Energy Up' program successfully tackles behavioral issues in adolescent girls by promoting healthy lifestyle habits and addressing food addiction. Participants experienced significant weight loss, with obese girls losing the most weight, while normal-weight girls gained expected weight for their age.
A large-scale study found that calcium and vitamin D supplements can slow weight gain in postmenopausal women. The benefits are most pronounced in those who weren't already meeting the daily recommended amount of calcium.
Research suggests that older-adult dieting won't lead to reduced physical function, with women losing muscle but maintaining aerobic fitness and strength. Weight regain also doesn't negatively impact physical performance, as long as the regained weight is not excessive fat.
A new University of Illinois study found that soy consumption leads to weight loss by increasing metabolism and not reducing food intake. Researchers discovered that soy protein hydrolysates can affect regulatory hormones and receptors in the brain, signaling a feeling of fullness and reducing body weight.
A new study has found that calorie-restricted diets with low or high glycemic loads result in comparable long-term weight loss. Participants lost an average of 8% of their original body weight, regardless of diet type, after one year on a 30% calorie-restricted diet.
A study of 31 long-term diet studies found that only a small minority of participants achieved sustained weight loss, while the majority regained weight. Exercise was found to be a key factor in maintaining weight loss, and dieting may even lead to negative health effects.
Researchers found that overweight teens who lost weight engaged in significantly more moderate to vigorous physical activity (7.6 hours/week for females, 11.7 hours/week for males) and spent less time watching TV compared to those who gained or maintained weight. This study provides valuable insights into behaviors associated with succ...
A study published by the American Academy of Neurology found that weight loss surgery can lead to vitamin B1 deficiency, resulting in memory loss, confusion, and other neurological problems. The syndrome, known as Wernicke encephalopathy, affects the brain and nervous system when the body lacks sufficient thiamine.
A study published in JAMA found that premenopausal women who followed the Atkins diet for 12 months lost more weight than those on other diets, including Zone, Ornish and LEARN. The low-carb diet resulted in greater weight loss and favorable lipid profiles.
The Stanford University School of Medicine study found that the Atkins diet was the most effective for weight loss among four popular diets. The women on the Atkins diet lost more weight and experienced greater improvements in cholesterol and blood pressure compared to those on other diets. The simplicity and high protein content of th...
The study reveals that leptin resistance causes the breakdown of the brain's appetite regulation system. Researchers found that a key gene called SOCS-3 plays a critical role in this process and may be targeted to aid in weight loss. The research provides new insights into obesity and potential therapeutic strategies.
Participation in sports that emphasize weight loss is strongly linked to unhealthful weight-control behaviors and steroid use among adolescents. Additionally, dieting may predict weight gain in teens due to long-term adoption of counterproductive behavioral patterns.
A new study found that including protein from lean sources of pork in your diet can help retain more lean body mass, which includes muscle, while losing weight. The study, conducted by Dr. Wayne Campbell and his colleagues, evaluated the weight loss of 46 overweight or obese women who followed one of two reduced-calorie diets.
Researchers at Université Laval found that taking calcium and vitamin D supplements while on a low-calorie diet reduces the risk of cardiovascular disease. The study, which lasted 15 weeks, showed significant drops in LDL cholesterol and increases in HDL cholesterol.
A new study conducted at NYU Medical Center found that lap band surgery is an effective procedure for combating obesity in adolescents. Patients who underwent the surgery lost approximately 50% of their excess weight within a year, with no significant complications.
A study published in Archives of Internal Medicine found that weight loss through calorie restriction leads to decreased bone mineral density, increasing the risk for osteoporosis and hip fractures. In contrast, weight loss through exercise does not seem to produce the same effect.
Two Stanford/Packard studies confirm pro-eating disorder websites promote dangerous behaviors among adolescents, while also finding pre-teens with eating disorders tend to lose weight more quickly. Pediatricians and parents should be vigilant about internet use and recognize early signs of weight loss in pre-teen children.
Men who experience weight fluctuations may be at higher risk for developing gallstones, according to a recent study. Weight cycling, or repeatedly losing and regaining weight, was found to increase the risk of gallstone disease by 21-76% compared to those who maintained a stable weight.
A new study found that exercising regularly can lead to more effective weight loss than following a calorie-restricted diet, as exercise helps preserve muscle mass and improve aerobic capacity. Those who exercised lost between 9-10% of their body weight, while dieters lost 9-10%, but also experienced reduced muscle mass.
A new study by Saint Louis University researcher Edward Weiss found that both diet and exercise provide significant benefits in reducing the risk of diabetes. The study, which followed 50-60 year olds with a high body mass index, showed improvements in glucose tolerance and insulin levels in all three groups, regardless of whether they...
A new study by The Miriam Hospital and Brown Medical School found that daily weighing and taking quick action when needed can significantly help dieters maintain weight loss. Participants who weighed themselves daily had an 82% reduction in the odds of regaining five or more pounds compared to those who did not weigh daily.
In a year-long clinical trial, MK-0557, an antiobesity drug targeting the hunger-stimulating factor neuropeptide Y, failed to produce clinically meaningful weight loss. The drug showed modest weight loss in obese individuals but was not sufficient as a standalone treatment.
A 24-week multi-center, placebo-controlled phase III trial demonstrated Contrave's superiority in weight loss compared to placebo. Patients taking Contrave experienced an average excess of 7% weight loss from baseline, while those on the placebo saw only 1% weight loss.
A study published in Annals of Surgery found that duodenal switch surgery produced greater weight loss than gastric bypass in super-obese patients, resulting in higher success rates at one and three years post-surgery. The procedure also had fewer complications and improved nutritional outcomes.
A long-term study found that elderly participants who developed mild dementia showed a doubling of their average weight loss rate one year prior to diagnosis. Researchers believe this link may be useful for detecting Alzheimer's disease earlier.
Accelerating weight loss before dementia onset is linked to Alzheimer's disease, according to a study of 449 healthy adults. Those who lost weight weighed about eight pounds less than those without the disease.
Researchers found that increasing protein in the diet augments the body's PYY hormone, reducing hunger and aiding weight loss. High-protein diets stimulate greater release of PYY than high-fat or high-carbohydrate meals.
New research confirms the human body is designed to resist weight loss efforts due to strong mechanisms defending against caloric deficits. Dr. Neil King's studies demonstrate a 'plateau effect,' where weight loss from exercise and calorie restrictions stalls at a certain point.
A study published by the American Society of Plastic Surgeons found that weight loss can improve the appearance of cellulite in some women, but worsen it in others. Patients who lost more weight and had lower body mass index (BMI) experienced significant improvements.
A study by researchers at The Miriam Hospital and University of North Carolina found that both computerized and human feedback were effective in short-term weight loss. Participants who received automated counseling lost an average of 8-10 pounds, with 34% achieving a clinically meaningful weight loss.
A four-year study led by Temple University aims to test an internet-based telemedicine system to help overweight and obese African Americans lose weight. The program will be implemented through partnerships with several churches in North Philadelphia, where participants can access the study's website and moderated chat rooms for guidance.
A diet with a high carbohydrate content but a low glycemic index may help promote weight loss and reduce the risk of cardiovascular disease. Participants on diets with lower glycemic loads experienced greater fat loss, particularly in women.
A study comparing gastric bypass and gastric banding surgeries found that bypass procedures had lower complication rates, greater weight loss, and higher patient satisfaction. Gastric bypass also reduced obesity-related diseases such as hypertension and diabetes more effectively.
Individuals who maintain a normal weight without a history of obesity exhibit consistent behaviors, such as limiting fast food consumption and sustaining high levels of physical activity. In contrast, those who struggle to maintain their weight report a lack of consistency in their lifestyle habits.
Researchers discovered that women who develop dementia experience a decline in weight up to 10 years before memory loss. The study found that the brains of these women underwent changes before the onset of symptoms, potentially linked to postmenopausal hormonal changes or other factors.
A recent study found that individuals maintaining weight loss reported consuming more fat and fewer carbohydrates. Despite this shift, participants who maintained a low-calorie diet with moderate fat intake remained successful in weight loss maintenance.
A study of 23 clinical trials found that weight loss can predict a significant reduction in physical disability in patients with knee osteoarthritis. The research suggests that achieving a moderate weight loss of over 7.6% can lead to at least a moderate clinical effect on physical disability.
A study tested 35 volunteers with cheap and sophisticated pedometers to assess accuracy in free-living conditions. Results showed that only one in four pedometers fell within an acceptable range of variation, while overestimating steps taken in nearly two-thirds of cases.