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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Ancient fossils shed new light on evolution of sea worm

Fossils of a type of sea worm, Iotuba chengjiangensis, have provided new insights into the evolution of annelid worms. The discovery suggests that these worms diversified into different lineages around 515 million years ago, during the Cambrian explosion.

Found: A protective probiotic for ALS

Scientists at the CRCHUM have identified a protective probiotic for ALS, Lacticaseibacillus rhamnosus HA-114, that prevents neurodegeneration in the C. elegans worm model. The probiotic helps reduce motor disorders and restore balance to impaired energy metabolism, leading to a decrease in neurodegeneration.

SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

How do worms develop their gut?

A husband-and-wife research team at UC Riverside found a simpler gene network is involved in specifying the gut in nematodes related to Caenorhabditis elegans. The discovery was made possible by the COVID-19 pandemic, which freed up time for the researchers to explore their question of how nematodes develop their gut.

Scientists reveal an unexpected gene in transparent worms

Researchers have identified a new gene, NUCL-1, in the transparent roundworm C. elegans, which is linked to human neurodegenerative diseases such as ALS and Alzheimer's. The discovery challenges recent theories on the role of nuclear structures in these disorders.

Research team discovers central functions of innate immune cells

A study published in Nature identifies the central functions of group 2 innate lymphoid cells (ILC2s), which play a crucial role in combating parasitic diseases and promoting mucus production. The researchers found that ILC2s are essential for immune response and cannot be replaced without compromising its effectiveness.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

New research rewrites the evolutionary story of gills

New research published in Nature suggests that the earliest gills played a crucial role in ion regulation, contradicting traditional views on their evolution. The study found ion-regulating cells in the gills of lampreys, amphioxus, and acorn worms, revealing an early chapter in the evolutionary story of gills.

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Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

Riboflavin depletion leads to a 30% extension in lifespan in C. elegans

A new study found that depleting riboflavin in Caenorhabditis elegans worms extended their lifespan by 30%, promoting a favorable energetic state and activating protective pathways. This discovery offers a novel approach to longevity and metabolic diseases, such as Type 2 diabetes and fatty liver.

Longer life due to faulty RNA processing

Researchers discovered a gene mutation that causes faulty RNA processing in worms, leading to increased longevity. The PUF60 gene affects the mTOR signalling pathway, which regulates cell metabolism and has been a target for anti-aging drugs.

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Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

Breaking DNA Goldilocks-style

Researchers at Kyoto University have discovered a phosphorylation pathway that regulates meiotic double-strand break activity, ensuring genome stability. Enzymes ATR kinase and PP4 phosphatase work together to maintain a balance of DNA breaks, allowing for successful meiosis.

Medieval friars were ‘riddled with parasites’, study finds

A study of medieval Cambridge's Augustinian friary and local cemetery found that friars were almost twice as likely to be infected by intestinal parasites. The researchers suggest that the high infection rates among friars may have been due to their practice of manuring vegetable gardens with human faeces.

Noise affects life on the seafloor

Research by the Alfred Wegener Institute found that low-frequency noise from human activities stresses crustaceans, mussels, and worms on the seafloor, impacting their ability to transform sediment and maintain ecosystem function. This could have far-reaching consequences for nutrient cycling and food availability in marine ecosystems.

Sleeping giant could end deep ocean life

A new study by researchers at University of California - Riverside found that the position of continents can have a devastating effect on deep ocean creatures. Continental movement can cause a sudden collapse in global water circulation, leading to a stark separation between oxygen levels in the upper and lower depths.

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Researchers crack 30 year old mystery of odor switching in worms

Researchers have identified a molecular mechanism behind worm olfaction, revealing how they discriminate between over 1,300 scents despite having only 32 olfactory neurons. The discovery involves the conserved protein arrestin, which helps fine-tune multiple sensations in both worms and humans.

Worms as a model for personalized medicine

Researchers used C. elegans to investigate inter-individual variation in metabolism and found genetic variants that affect metabolic differences between individuals. They discovered unique metabolites in different strains of the worm, which could help tailor biomedical recommendations to individual metabolism.

Molecular mechanism behind migration revealed in salt-seeking worms

A team at the University of Tokyo discovered that syntaxin protein plays a vital role in storing memory in the nervous system, influencing the migratory behavior of nematodes. The study found that altering syntaxin can lead to reversed behavior, allowing worms to choose whether to approach or avoid salt concentrations.

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New insights into the complexity of the brain

A recent study out of the Complexity Science Hub Vienna developed a mathematical and computational framework for analysing neural activity in C. elegans, a tiny worm used to study neural activity. The study proposes a way to unmask the roles of neurons by using more natural perturbations.

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Why hungry worms take risks

Researchers used worms to study how hunger signals in the gut communicate with the brain, leading to riskier behavior. The findings suggest that proteins in intestinal cells move dynamically to transmit signals about hunger, driving worms to cross toxic barriers.

Research brief: Immune response to parasitic worms

A study led by the University of Minnesota Medical School found that exposure to helminths can stimulate the immune system and reduce predisposition for inflammatory bowel disease. The research revealed a unique glycosylation mechanism, O-GlcNAcylation, which activates epithelial cells to orchestrate an anti-helminth response.

Meta Quest 3 512GB

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Tiny worms make complex decisions, too

Worms use cost-benefit calculations to choose between different actions, similar to vertebrates. The study demonstrates that complex decision-making capabilities can be encoded in small biological networks.

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Sperm or eggs? How hermaphroditic worms distribute their resources

Researchers discovered two dominant strategies among flatworms: reciprocal males receive more resources, while hypodermic mated species invest heavily in female organs. Self-fertilization in these species increases with hypodermic mating, suggesting a common evolutionary principle between plants and worms.

Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Thread spread - A never-before-seen way bacteria infect cells

Researchers at San Diego State University have discovered a novel way bacteria infect cells by producing long threads, which grows up to 100 times the size of a bacterium in 30 hours. This mechanism allows the bacteria to rapidly infect multiple cells and access more nutrients for growth.

Silencing tool quashes gene activity across generations

Scientists have developed a gene-silencing tool that can quash gene activity across generations using small noncoding RNA molecules. This technique, called piRNAi, has expanded the molecular toolkit for gene manipulations and allows for more detailed investigations in nematode worms.

UCR scientists discover tarantula-killing worms

Scientists at UCR have discovered a new species of nematode parasite that infects and kills tarantulas, exhibiting strange behaviors like walking on tiptoe and loss of fang control. The parasite, Tarantobelus jeffdanielsi, is named after actor Jeff Daniels, who saved fictional spiders in the 1990 film Arachnophobia.

Sony Alpha a7 IV (Body Only)

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DJI Air 3 (RC-N2)

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Unlocking the secrets of a critical schistosomiasis drug

Two independent teams of researchers have found the molecular mechanism of action of praziquantel, the only approved drug to treat schistosomiasis. The drug binds to a specific type of channel in the cell membrane, causing calcium ions influx and resulting in worm paralysis and death.

Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

Reading the mind of a worm

Researchers used a machine-learning algorithm to identify differences in how the brain responds to various chemicals, including salt and benzaldehyde. The study provides insight into how brains process information and may help understand sensory processing disorders.

Study finds that ancient penis worms invented the “hermit crab” lifestyle

Researchers at Durham University and Yunnan University discovered that ancient penis worms took shelter in empty shells, adopting the 'hermit crab' lifestyle. This adaptation allowed them to survive in environments with high predator pressure, highlighting the key role of predation in shaping early animal evolution.

Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.