Articles tagged with Worms
The Center for C. elegans Anatomy is receiving $2.6 million in funding from the NIH to expand WormAtlas, a resource for researchers studying C. elegans and other nematodes. The expansion aims to incorporate new nematode species into the atlas, enabling comparisons between C. elegans and less-studied species.
Researchers explore cellular senescence's complex relationship with growth stimulation and cell cycle arrest, revealing potential anti-aging drug targets. Understanding these mechanisms is crucial for developing new treatments for age-related diseases.
A tiny worm called C. elegans is enabling scientists to explore the emerging theory that Parkinson’s disease starts in the gut, where a sticky protein causes neurons to die. The worms have a digestive tract and neurotransmitters similar to humans, making them a great model for studying cognitive problems associated with Parkinson's.
Researchers developed MoBIE, a user-friendly tool for sharing and exploring large image data sets. The tool allows for visualization and analysis of huge amounts of data from hundreds of sources, making it easier for researchers to analyze and interpret microscopy data worldwide.
A high-fat diet allows the immune system to eliminate a parasitic worm that causes long-lasting infections in the large intestine. This discovery may lead to new treatments for millions suffering from intestinal parasitic infections worldwide.
Fossils of a type of sea worm, Iotuba chengjiangensis, have provided new insights into the evolution of annelid worms. The discovery suggests that these worms diversified into different lineages around 515 million years ago, during the Cambrian explosion.
Scientists at the CRCHUM have identified a protective probiotic for ALS, Lacticaseibacillus rhamnosus HA-114, that prevents neurodegeneration in the C. elegans worm model. The probiotic helps reduce motor disorders and restore balance to impaired energy metabolism, leading to a decrease in neurodegeneration.
A husband-and-wife research team at UC Riverside found a simpler gene network is involved in specifying the gut in nematodes related to Caenorhabditis elegans. The discovery was made possible by the COVID-19 pandemic, which freed up time for the researchers to explore their question of how nematodes develop their gut.
Researchers have identified a new gene, NUCL-1, in the transparent roundworm C. elegans, which is linked to human neurodegenerative diseases such as ALS and Alzheimer's. The discovery challenges recent theories on the role of nuclear structures in these disorders.
A new study led by Weill Cornell Medicine researchers offers insight into the immune mechanisms of inflammatory disease. Group 2 innate lymphoid cells (ILC2s) have an essential role in protecting tissues from parasitic infections and allergic inflammation.
A study published in Nature identifies the central functions of group 2 innate lymphoid cells (ILC2s), which play a crucial role in combating parasitic diseases and promoting mucus production. The researchers found that ILC2s are essential for immune response and cannot be replaced without compromising its effectiveness.
A new protocol for live imaging of adult C. elegans has been developed, extending imaging time to over two hours while avoiding heat stress in the specimen. This breakthrough allows for high-resolution imaging of cell dynamics and developmental processes.
New research published in Nature suggests that the earliest gills played a crucial role in ion regulation, contradicting traditional views on their evolution. The study found ion-regulating cells in the gills of lampreys, amphioxus, and acorn worms, revealing an early chapter in the evolutionary story of gills.
Scientists at NTU Singapore have found that a stress response in cells, when 'switched on' at a post-reproductive age, could be the key to slowing down aging. The study showed that this stress response extended the lifespan of roundworms fed a high-glucose diet.
A study in C. elegans suggests that disrupting meiosis in reproductive cells accelerates aging and triggers a decline in healthspan, similar to humans. The research highlights the importance of reproductive fitness for overall health, with potential applications for early detection and treatment of age-related diseases.
A new study found that depleting riboflavin in Caenorhabditis elegans worms extended their lifespan by 30%, promoting a favorable energetic state and activating protective pathways. This discovery offers a novel approach to longevity and metabolic diseases, such as Type 2 diabetes and fatty liver.
Researchers discovered a gene mutation that causes faulty RNA processing in worms, leading to increased longevity. The PUF60 gene affects the mTOR signalling pathway, which regulates cell metabolism and has been a target for anti-aging drugs.
A cercarial dermatitis outbreak occurred in Chana district, South Thailand, affecting rice farmers, due to ruminant parasites like Schistosoma indicum. The study identified two snail species as intermediate hosts for flatworms causing the disease.
Threespine stickleback fish evolved resistance to freshwater tapeworms by forming scar tissue around them, which prevents the worms from growing. However, this defense has a significant fitness cost for female sticklebacks, as they are 80% less likely to successfully breed due to the accumulated scarring.
Researchers at Kyoto University have discovered a phosphorylation pathway that regulates meiotic double-strand break activity, ensuring genome stability. Enzymes ATR kinase and PP4 phosphatase work together to maintain a balance of DNA breaks, allowing for successful meiosis.
Researchers genetically mapped one of the oldest human parasites, the whipworm, using stool samples from Viking latrines. The study reveals a delicate relationship between humans and the parasite, which can make us healthier or ill, and provides new knowledge on its development and prehistoric dispersal.
Research by the Alfred Wegener Institute found that low-frequency noise from human activities stresses crustaceans, mussels, and worms on the seafloor, impacting their ability to transform sediment and maintain ecosystem function. This could have far-reaching consequences for nutrient cycling and food availability in marine ecosystems.
A study of medieval Cambridge's Augustinian friary and local cemetery found that friars were almost twice as likely to be infected by intestinal parasites. The researchers suggest that the high infection rates among friars may have been due to their practice of manuring vegetable gardens with human faeces.
A new study by researchers at University of California - Riverside found that the position of continents can have a devastating effect on deep ocean creatures. Continental movement can cause a sudden collapse in global water circulation, leading to a stark separation between oxygen levels in the upper and lower depths.
Researchers have discovered a novel strategy for preventing and treating parasites and allergies by harnessing the power of adenosine, a molecule released by injured cells. This breakthrough could lead to the development of vaccines and treatments that target this 'danger signal', which is released when cells are damaged.
Researchers have identified a molecular mechanism behind worm olfaction, revealing how they discriminate between over 1,300 scents despite having only 32 olfactory neurons. The discovery involves the conserved protein arrestin, which helps fine-tune multiple sensations in both worms and humans.
Researchers used C. elegans to investigate inter-individual variation in metabolism and found genetic variants that affect metabolic differences between individuals. They discovered unique metabolites in different strains of the worm, which could help tailor biomedical recommendations to individual metabolism.
A team of researchers developed a model system to study individual differences in metabolism using C. elegans worms. They identified a novel metabolic condition linked to variation in the hphd-1 gene, which has implications for personalized medicine and tailoring dietary advice and disease treatment to an individual's genome sequence.
A new study reveals that bottom burrowing animals were among the first to recover after the end-Permian mass extinction. The research, led by Dr. Xueqian Feng, used ancient sea bed burrows and trails to reconstruct the recovery stages of various animal groups.
A team at the University of Tokyo discovered that syntaxin protein plays a vital role in storing memory in the nervous system, influencing the migratory behavior of nematodes. The study found that altering syntaxin can lead to reversed behavior, allowing worms to choose whether to approach or avoid salt concentrations.
Researchers discovered that moonlight adjusts the reproductive cycle of marine bristle worms to specific hours during the night. The study reveals how light receptors decode sun- and moonlight to adjust the plastic daily clock, which is essential for species survival.
A recent study out of the Complexity Science Hub Vienna developed a mathematical and computational framework for analysing neural activity in C. elegans, a tiny worm used to study neural activity. The study proposes a way to unmask the roles of neurons by using more natural perturbations.
A new study published in PNAS reveals that a specific bacterial compound, lipopolysaccharide, induces larval marine tubeworms to settle on the seafloor and undergo metamorphosis. The discovery offers hope for coral reef restoration, mariculture, and biofouling prevention.
Researchers used worms to study how hunger signals in the gut communicate with the brain, leading to riskier behavior. The findings suggest that proteins in intestinal cells move dynamically to transmit signals about hunger, driving worms to cross toxic barriers.
Bloodworms use copper harvested from sediments to form their jaws, which are strong enough to last five years. The worm synthesizes a material with mechanical properties similar to manufactured metals through a complex process involving protein and melanin.
Research reveals high rates of parasitic worm infections in ancient British populations, particularly during the Roman and Medieval periods. The study sheds light on the lives and habits of past populations, providing insights into public health measures.
A study led by the University of Minnesota Medical School found that exposure to helminths can stimulate the immune system and reduce predisposition for inflammatory bowel disease. The research revealed a unique glycosylation mechanism, O-GlcNAcylation, which activates epithelial cells to orchestrate an anti-helminth response.
Researchers found that earthworms prefer soils with bioplastic particles and digest them differently than petroleum-derived plastics. The worms can break down bioplastics like polylactic acid into smaller fragments, which are then excreted slowly.
A study published in Applied and Environmental Microbiology reveals that geosmin, a common soil contaminant, acts as an aposematic signal to deter bacteria-eating worms like C. elegans from poisonous microbes. The researchers found that geosmin triggers the worm's sense of taste, warning it of potential danger.
Researchers have created a 'worm-on-a-chip' device that uses roundworms to detect lung cancer cells, showing 70% accuracy. The device could potentially help doctors diagnose cancer at an earlier stage non-invasively.
Worms use cost-benefit calculations to choose between different actions, similar to vertebrates. The study demonstrates that complex decision-making capabilities can be encoded in small biological networks.
A new study by Emory University finds that schistosome transmission can be highest when freshwater snail populations are low. Snails competing for resources may lead to lower infectivity rates, contrary to typical pesticide-based control methods.
A study led by LSU researchers has found that a natural plant extract called Artemisia scoparia can increase the lifespan of roundworms by 40% and improve their metabolic health. The extract, which is native to Asia, was fed to worms in various doses and showed significant effects on fat regulation and stress resistance.
Researchers discovered two dominant strategies among flatworms: reciprocal males receive more resources, while hypodermic mated species invest heavily in female organs. Self-fertilization in these species increases with hypodermic mating, suggesting a common evolutionary principle between plants and worms.
Researchers found that epigenetic inheritance can affect the genetic composition of a population for multiple generations. Exposure to high temperatures accelerated the rate of evolution, increasing the spread of genes through mating.
Researchers found that stressed worms produce more sexually attractive offspring by transferring small RNAs, which influence gene expression. This epigenetic inheritance allows the trait to persist across generations without DNA changes.
Researchers at San Diego State University have discovered a novel way bacteria infect cells by producing long threads, which grows up to 100 times the size of a bacterium in 30 hours. This mechanism allows the bacteria to rapidly infect multiple cells and access more nutrients for growth.
Scientists have developed a gene-silencing tool that can quash gene activity across generations using small noncoding RNA molecules. This technique, called piRNAi, has expanded the molecular toolkit for gene manipulations and allows for more detailed investigations in nematode worms.
A team of scientists from Germany, Spain, Australia and Japan discovered a new species of branching marine worm, Ramisyllis kingghidorahi, in Japan. The worm has a unique body shape with one head and multiple posterior ends, living inside the internal canals of sea sponges.
Scientists at UCR have discovered a new species of nematode parasite that infects and kills tarantulas, exhibiting strange behaviors like walking on tiptoe and loss of fang control. The parasite, Tarantobelus jeffdanielsi, is named after actor Jeff Daniels, who saved fictional spiders in the 1990 film Arachnophobia.
Researchers discovered the ZIP-1 gene acts as a cell's first-line response to infection, controlling immune responses to viruses and other threats. The finding could have implications for identifying similar genes that control immune responses in humans.
Researchers discovered nine genes in S. mansoni's autophagy pathway inhibited by the primate's immune system, preventing parasite multiplication and contaminating the host. The study suggests a potential novel therapy and vaccine against schistosomiasis.
The study's findings provide a foundation for developing efficient protein isolation techniques from insect powders, which could help address global hunger and malnutrition issues. Insect-based protein sources are rich in essential amino acids and offer a sustainable alternative to traditional farming methods.
Two independent teams of researchers have found the molecular mechanism of action of praziquantel, the only approved drug to treat schistosomiasis. The drug binds to a specific type of channel in the cell membrane, causing calcium ions influx and resulting in worm paralysis and death.
Researchers have solved the mystery of how praziquantel works, a key to treating schistosomiasis. The discovery highlights new opportunities for drug development and may help combat this debilitating disease affecting over a billion people worldwide.
Younger male exposures to Ascaris roundworms show striking reductions in lung function and nearly five times higher odds of having asthma. The study highlights a previously overlooked risk factor for respiratory health in Europe.
Researchers have discovered that marine worms must develop a certain number of body segments before forming their original reproductive cells. This finding could have major implications for human stem-cell research and infertility treatments.
A new confocal platform using artificial intelligence and multiple lenses improves volumetric resolution by over 10-fold while reducing phototoxicity. The platform uses Deep Learning algorithms to distinguish between high-quality images with low signal-to-noise ratio and better images.
Researchers at MDI Biological Laboratory discovered that muscle tissue is protected from reduced protein synthesis during nutrient scarcity, accelerating growth and reproduction. The study suggests potential for developing anti-aging drugs preserving muscle tissue while prolonging lifespan.
Researchers used a machine-learning algorithm to identify differences in how the brain responds to various chemicals, including salt and benzaldehyde. The study provides insight into how brains process information and may help understand sensory processing disorders.