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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

What it means when animals have beliefs

Researchers from Ruhr-University Bochum have identified four criteria for understanding animal beliefs, including the ability to use information flexibly and recombine components in novel ways. These criteria are met by various species, such as crows, scrub jays, rats, chimpanzees, and border collies.

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Dopamine signaling allows neural circuits to generate coordinated behaviors

Researchers at MIT's Picower Institute discovered that dopamine signaling plays a crucial role in coordinating distinct behavioral outputs in C. elegans, enabling the animals to disperse eggs efficiently across a nutrient-rich environment. By analyzing high-frame-rate videos of nematodes using a custom microscopy platform, the team ide...

Subcellular chatter regulates longevity

Research at Max Planck Institute for Biology of Ageing reveals that NFYB-1 regulates mitochondrial function through lysosomal prosaposin, a key factor in cellular longevity. The study used Caenorhabditis elegans as a model organism and found that restoring cardiolipins improved worm health.

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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Worms freeload on bacterial defense systems

A team of scientists discovered a sensory circuit in worms that allows them to choose between spending energy on self-defence and relying on nearby bacterial protection. The discovery suggests that the presence of E. coli bacteria is crucial for peroxide resistance, which could lead to improved health and longevity in humans.

Tube worm slime displays long-lasting, self-powered glow

Researchers discovered that tube worm slime contains an iron storage protein called ferritin, which acts as a molecular battery storing energy. Artificially adding iron to the mucus increases light production, enabling a self-sustaining bioluminescence process.

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Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

New active ingredient against allergic asthma

Researchers from TUM have identified a substance that worm larvae use to modulate the host's immune response, activating anti-inflammatory pathways and reducing inflammatory mediators. This active molecule shows promise as a new treatment for chronic airway inflammation in allergic asthma.

New algorithm to help process biological images

A new algorithm for segmenting biological objects in complex images has been developed by Skoltech researchers. The method uses a two-step neural network training algorithm that can learn from small datasets and achieve high accuracy in isolating individual cells, organisms, and parts of plants.

Researchers identify link between obesity and sleep loss in worms

A new study published in PLOS Biology found that excess weight can cause poor sleep in worms, not the other way around. Researchers genetically modified worms to lose their ability to sleep and observed a severe drop in energy levels, suggesting that sleep is an attempt to conserve energy.

Some worms programmed to die early for sake of colony

A UCL-led study reveals that certain organisms, like C. elegans roundworms, possess self-destruct programs to prevent overliving and benefit their colonies. This adaptive mechanism reduces food demand and increases reproductive success, providing a winning strategy for the community.

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Deep-sea worms and bacteria team up to harvest methane

Scientists have discovered a unique symbiosis between deep-sea worms and methanotrophic bacteria that harnesses methane as a carbon source. The worms absorb the energy from methane by slowly digesting the bacteria, effectively becoming methanotrophs themselves.

'Sushi parasites' have increased 283-fold in past 40 years

A new study found a dramatic increase in the global abundance of Anisakis worms, also known as herring worms, which can be transmitted to humans through raw or undercooked seafood. The parasite's rise could have implications for human health and marine mammal populations.

Rapid, automatic identification of individual, live brain cells

Researchers developed a computer program to identify each nerve cell in fluorescent microscope images of living worms, overcoming previous challenges by creating unique genetic modifications. The program uses a mathematical algorithm to analyze images and assign neuron identities based on position variations between individual animals.

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Worm nerve responses for good and bad

Researchers discovered a temperature-sensing nerve cell that transmits signals activating or inhibiting receiving nerve cells, explaining how worms respond to good or bad temperatures. Genetic studies identified three conserved genes involved in this response, suggesting a similar mechanism may exist in higher organisms.

Scientists identify new target for Parkinson's therapies

Researchers discovered a new master control region in alpha-synuclein protein that controls amyloid formation, leading to neurodegeneration and movement difficulties. This finding opens up new opportunities to develop therapies to slow down or prevent Parkinson's disease.

Tissue-digging nanodrills do just enough damage

Researchers have successfully tested molecular motors that can destroy diseased cells in worms, plankton, and mice. The nanomachines caused various degrees of damage to tissues, showing their potential for treating skin diseases such as melanomas and eczema.

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Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Unlocking animal behavior through motion

Researchers use physics and technology to track animal movement, revealing key findings on flock behavior, neural network tracking, and burrowing forces. By analyzing animal motion, scientists gain a deeper understanding of collective behavior and individual animal actions.

Parasitic worms have armies, and produce more soldiers when needed

A new study found that parasitic trematode worms produce greater standing armies in areas of greater threat, demonstrating for the first time that animal societies can adjust army size to meet threat levels. The research showed that snails collected in locations with high risk of invasion had larger numbers of soldier worms.

Brain cells protect muscles from wasting away

Researchers found that a mere four glial cells in the worm's brain control the stress response in cells throughout its body, increasing lifespan by 75%. This discovery suggests that brain cells may play a crucial role in protecting muscles from wasting away, and potentially lead to new treatments for muscle atrophy and obesity.

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Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

Scientists aim to learn how serotonin modulates behavior

Researchers at MIT's Picower Institute will employ a nematode worm model to understand how serotonin modulates brain states and behavior. They aim to map out which combinations of serotonin receptors mediate its effects on behavior and analyze how serotonin alters whole-brain activity.

Biologists reveal cellular architecture of potential fountain of youth

Researchers Alyssa Johnson and Adam Bohnert have discovered a new class of lysosomes, dubbed 'tubular lysosomes,' which can form complex networks that affect aging, disease, and stressors. Their findings could lead to medical therapies and treatments to extend health and longevity in humans and animals.

Antioxidant reverses BPD-induced fertility damage in worms

A study published in Genetics found that Coenzyme Q10 reversed most of the reproductive harms caused by exposure to BPA in Caenorhabditis elegans worms. The antioxidant improved or reversed multiple types of damage, including lower rates of egg cell death and fewer chromosome abnormalities.

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Avatar worms help to identify factors that modify genetic diseases

Researchers used CRISPR gene-editing to introduce human mutations into C. elegans worms, identifying genes that modify disease progression and pinpointing harmful drugs. The study found three candidate disease-modifier genes and demonstrated the importance of screening for potential harm in patients with genetic mutations.

Researchers develop tool to identify molecular receptors in worms

Researchers at Worcester Polytechnic Institute have developed a new tool to identify molecular receptors in Caenorhabditis elegans worms involved in sensing pheromones. This breakthrough could speed up neuroscience research into pheromones by streamlining the process and identifying specific receptors in just a month.

Plants found to speak roundworm's language

Researchers found plants manipulate nematode pheromones to repel these pests, which cause more than $100 million in damage to crops every year. Plants metabolize ascarosides and secrete the metabolites back into the soil, broadcasting propaganda that 'this is a bad place'.

Break point

Researchers found that DEHP disrupts meiosis in worms, leading to defects during egg formation and early embryonic development. The chemical causes excessive DNA breaks and interferes with the system that repairs them, resulting in abnormal chromosomes and reduced embryo viability.

Ghost worms mostly unchanged since the age of dinosaurs

A team of biologists discovered a group of annelid worms that have remained largely unchanged for 275 million years, despite their distinct genetic makeup. The Stygocapitella worms' slow evolution is attributed to their adaptation to stable environments, with changes potentially linked to population crashes or developmental constraints.

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U-M researchers discover stress in early life extends lifespan

Researchers at the University of Michigan discovered that oxidative stress in early life increases subsequent stress resistance later in life. Oxidative stress, which occurs when cells produce more oxidants than they can deal with, is part of the aging process but can also arise from stressful conditions.

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American University researchers sequence genome of the 'devil worm'

The Devil Worm's genome reveals an unusually large number of heat-shock proteins and extra copies of cellular survival genes, suggesting its evolutionary adaptation to lethal environmental conditions. The discovery may provide lessons for humans on how to adapt to a warming climate, with potential applications in understanding life bey...

WSU genetic discovery holds implications for better immunity, longer life

Researchers found that the nervous system controls a worm's skin-like barrier against bacterial infections, challenging traditional views on innate defense. The discovery may have implications for human health and longevity by regulating collagen production, a key protein in maintaining tissue structure.

CRISPR-edited C. elegans identifies vulnerabilities in cancer

Researchers used CRISPR gene editing to mimic human SF3B1 mutations in C. elegans worms, identifying three splicing factors as potential targets for cancer therapy. The study also humanized a region of the SF3B1 protein binding site, enabling testing of Pladienolide B-derived molecules.

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Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Parasite paralysis: A new way to fight schistosomiasis?

A research team has isolated a potent compound that paralyzes parasitic worms causing devastating health problems. The discovery could lead to new ways to fight schistosomiasis, a disease with no alternative treatment besides praziquantel.

Catching evolution in the act

Researchers found that natural selection acts on signal-sensing receptors, influencing a worm's decision to stay or enter dauer based on the availability of resources. The study provides evidence that artificial and natural selection work similarly, supporting Darwin's hypothesis.

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Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

Tapeworms need to keep their head to regenerate

A recent study published in eLife reveals that tapeworm regeneration is dependent on stem cells located near the head. Researchers found that severing the head did not prevent regrowth, but signals from the neck are necessary to activate stem cells.

Researchers show how railroad worms produce red light

Researchers have discovered a new bioluminescence mechanism in railroad worm Phrixothrix hirtus, emitting red light through the size of its luciferase cavity. This discovery has potential for biomedical applications like imaging muscles and blood tissue.

Wild animals' immune systems decline with age, sheep study finds

A study on Soay sheep reveals that their immune responses to parasitic worms decline through adulthood, leading to increased mortality rates. The findings provide the first evidence linking declining immune function and survival in wild animals, highlighting a critical issue for human health as well.

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Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.

The sleep neuron in threadworms is also a stop neuron

The RIS neuron in threadworms serves both to induce sleep after shedding its cuticle or recovering from stress, and to halt movement during locomotion, enabling the worm to change direction or avoid danger. This dual function highlights the complexity of simple life forms like worms.

New research from Alkema lab shows how stress can weaken defenses

Research from the Alkema lab reveals that the 'fight-or-flight' response triggers tyramine release, which stimulates insulin pathways to satisfy energy demands but down-regulates cellular protection against environmental stress. This dynamic regulation negatively impacts health and aging in nematode worms.

This protein is how creatures sense cold, researchers discover

Researchers have identified a receptor protein that can detect extreme cold temperatures in creatures. The study found that the glr-3 gene, responsible for making the GLR-3 receptor protein, is required for worms to sense cold temperatures and is evolutionarily conserved across species.

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Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

How worms snare their hosts

A study by the University of Bonn found that parasitic worms, such as Pomphorhynchus laevis, use bright orange coloring to attract specific host fish like barbels and sticklebacks. This strategy increases infection rates in these species, which are suitable for the parasite's reproduction.

The secret of fireworm is out: molecular basis of its light emission

A team of researchers has discovered the molecular basis of fireworms' bioluminescence, revealing a novel chemical structure for luciferin. The findings provide insight into a completely new mechanism of light emission and hold potential for developing new bioluminescence-based applications.

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Drawing inspiration from natural marvels to make new materials

UD researchers create a network of synthetic materials mimicking the mechanical gradient of a bristle worm's jaw system, governing its mechanical properties through metal coordination chemistry. This breakthrough enables the development of new materials for various applications, including soft robotics and medical devices.

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Leaping larvae! How do they do that without legs?

Researchers at Duke University discovered that gall midge larvae use a hydrostatic legless jumping mechanism, which allows them to launch themselves through the air with incredible speed and efficiency. This remarkable behavior is made possible by sticky patches of skin on the larva's body, similar to those found on geckos' feet.

Detox pathway extends lifespan of the worm C. elegans

A mutant worm with a change in one mitochondrial gene produces more ROS, but lives twice as long due to a detoxification pathway. The study reveals that this pathway is conserved throughout the animal kingdom and essential for longevity.

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