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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Shifts in the microbiome impact tissue repair and regeneration

Researchers found that a dramatic shift in the microbial community of planaria robs it of regenerative abilities, similar to observed shifts in human inflammatory disorders. The study provides a valuable model for understanding the interplay between immunity and regeneration.

Targeting the gut-brain connection can impact immunity

A study by Duke University researchers found that manipulating dopamine signaling can control inflammation in the gut, providing a proof of principle for using drugs originally designed to target the nervous system to treat immune system disorders such as rheumatoid arthritis and autoimmune disease.

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GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

Sex and death insights from a mutant roundworm

Researchers at Georgia Tech discovered a genetic mutation in C. elegans that led to prioritization of adult survival over reproduction, revealing insights into life history trade-offs and their regulation. The study's findings have implications for understanding human genetics, particularly the NURF-1 gene involved in reproduction.

New clue to how lithium works in the brain

MIT biologists identify a key protein inhibited by lithium, leading to reduced worm activity, suggesting a mechanism for lithium's effects on the brain; the findings propose a new hypothesis linking BPNT1 inhibition to mood stabilization in humans

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Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Old specimens establish a new bamboo worm genus and species

PhD student Wang Yueyun and Dr Li Xinzheng discover two new species and a new genus of bamboo worms in the open access journal ZooKeys. The new genus is characterized by a unique collar-like glandular band on its sixth chaetiger, setting it apart from other Maldaninae subfamily members.

What makes a small worm a popular model

Researchers created a comprehensive metabolic model of C. elegans, linking over 2,000 processes to identify genes contributing to lifespan extension. The 'ElegCyc' model enables analysis of large datasets and will aid in understanding human diseases and microbiome interactions.

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Intestinal worms boost immune system in a surprising way

Researchers discovered that intestinal worm infections trigger a significant increase in lymph node size and B-cell production, leading to enhanced antibody response. The study provides new insights into the complex interactions between the host and parasites.

Slow worms react quickly to climate change

Researchers exposed small worms to artificial climate change, finding that a half-degree warmer soil caused rapid genome changes. The study provides insight into evolution's ability to adapt to climate change, suggesting it may be more resilient than previously thought.

How parasitic worms help minimize inflammatory bowel disease

Parasitic worms, or helminths, have been found to beneficially influence the composition of gut microbiota in individuals with inflammatory bowel disease. By infecting mice deficient in a gene that models Crohn's disease, researchers discovered that these parasites restore a compromised layer of mucus and intestinal cell morphology.

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The Red Queen rules

A study by University of Iowa researchers found that female New Zealand freshwater snails that reproduce sexually are more resilient to parasitic worms than females that produce offspring asexually. The team tested the hypothesis in Lake Grasmere, finding that male snails were present even in areas with low parasite activity.

Maple syrup protects neurons and nurtures young minds

Researchers discovered that maple syrup, rich in polyphenols, can prevent the development of ALS in C. elegans worms by protecting neurons from toxic proteins. The study found that a combination of sugar and polyphenols may have a neuroprotective effect.

A common brain cell shapes the nervous system in unexpected ways

A new study reveals that glial cells play a dynamic role in shaping nerve endings, controlling neuron connections and functions. Glial cells use specific molecular mechanisms to regulate the shapes of different neuronal cell types, including those expressing temperature- or odor-sensing proteins.

A newly discovered way for cells to die

Scientists at Rockefeller University have identified a new way for cells to die in the linker cell of Caenorhabditis elegans, resembling neuronal death in humans. The discovery suggests that this process might be involved in neurodegenerative disorders and could serve as a target for future drugs.

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To keep or not to keep a hookworm

Researchers at UC Riverside have identified an immune protein called RELMalpha that protects the body from damage caused by hookworm infections. The protein is found in mice and is expected to function similarly in humans.

Symbiosis with partner exchange

Researchers found that bacteria in roundworms are loyal to their hosts, while those in segmented worms prefer local locations, with external tenants showing more long-term loyalty than internal cohabitants.

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Brain activity of nematodes seeking food offers new view on sleep

Researchers at University of Oregon discovered a connection between brain activity in nematode worms and human sleep disorders, finding similar fragmentation patterns. This study provides a framework to understand genetic and physiological underpinnings of neural circuitry involved in sleep.

Molecule induces lifesaving sleep in worms

A molecule has been identified that promotes a sleep-like state in nematode worms, which is similar to the sleep of humans and other mammals. The protein VAV-1 regulates this process and is also involved in maintaining normal amounts of EGFR in the neuron.

What happens to pharmaceuticals in the digestive system of a bird?

A new study by the University of York investigates how commonly-prescribed pharmaceuticals like Prozac affect starlings when ingested through their natural prey. The research developed an in-vitro model to simulate a bird's digestive system, revealing that the drug behaves similarly in both birds and humans.

Fine-tuning cellular energy increases longevity

Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified ARGK-1 as a protein that can extend the natural lifespan of C. elegans by increasing energy regulation within cells. This finding may lead to new avenues for delaying human age-related diseases such as cancer and neurodegenerative disorders.

Tracking worm sex drive, neuron by neuron

A team of researchers at Worcester Polytechnic Institute and California Institute of Technology has found a neural network in male worms that processes sex-specific sensory cues, allowing them to make decisions about pursuing mates. The network involves four male-specific sensory neurons that communicate with each other through synapti...

Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Worm study may resolve discrepancies in research on aging

A recent Brown University-led study has resolved long-standing discrepancies in research on aging by identifying the human chemotherapy drug FUdR as a key factor. The study found that FUdR triggers stress response and DNA repair pathways in C. elegans worms, allowing them to better endure adverse conditions and lengthening their lifespan.

Ancient lone star lizard lounged in lush, tropical Texas

Researchers discovered a new species of extinct worm lizard in Texas, dubbed the 'Lone Star' lizard. The discovery sheds light on how certain animal groups responded to climate change in the past and provides insight into potential future adaptations.

Observing brain diseases in real time

Researchers at EPFL have developed a highly innovative research tool: a 2cm by 2cm 'chip' with 32 independent compartments, each holding a nematode. This device enables the monitoring of individual worms and allows for precise control over nutrient concentrations and temperature.

TSRI study reveals new link between brain and fat-burning circuit

A new study led by TSRI scientists has found that oxygen sensing in the brain plays a role in metabolism and internal state sensing. The research discovered a connection between oxygen levels and fat reserves in animal models, suggesting a possible mechanism for regulating metabolism in humans.

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Cling-on warriors

A new type of underwater adhesive developed at UCSB replicates the adhesion strategy of the Sandcastle worm, which is robust in wet conditions. The synthetic glue promotes adhesion between various surfaces and is more resistant to cracking due to its porous structure.

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'Lifespan machine' probes cause of aging

A study published in Nature suggests that aging does not have a single molecular cause but is rather a systemic process. Researchers found a statistical regularity in how genetic and environmental factors affect the life span of Caenorhabditis elegans worms, revealing an unexpected uniformity among life span distributions.

Blocking fat transport linked to longevity

A new study reveals that blocking the production of a naturally occurring protein responsible for transporting fats around the body increases life span in nematodes and mice. The research suggests that this protein, VIT, hinders essential cell functions and prevents the reuse of fats for healthier purposes.

Genes for age-related cognitive decline found in adult worm neurons

A team of researchers from Princeton University has discovered new genes that regulate memory and neuron repair in adult worms, which could have implications for human cognitive decline and traumatic brain injury. The study provides a more complete picture of how insulin/IGF-1 signaling pathway controls gene expression in neurons.

How is a developing brain assembled?

Researchers developed a new 3D software to track the embryonic development and movement of neurons in Caenorhabditis elegans worms. The program creates a straightened image of the worm, allowing scientists to follow individual cells as they move and grow, revealing complex neuronal structures in unprecedented 3D clarity.

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Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.

Dead-easy test to tackle parasites

A new test, xWORM, uses the xCELLigence E-Plate to measure parasite motility, reducing time-consuming microscope checks and costs, offering a promising solution for treating parasitic worm diseases. The technology has potential applications in global health, particularly in tropical regions where such parasites infect millions of peopl...

Procreation trumps survival -- even on a cellular level

A newly discovered mechanism in worms suggests that mothers sacrifice their health for future generations, fueling egg cell development with fats. This phenomenon raises the possibility of a similar trait in humans, potentially impacting reproductive success and lifespan.

Infertile worms resist infection-induced neurodegeneration

Researchers have found that infertile animals appear to be protected from neurodegeneration in a study using C. elegans worms. The study, which appears online now, showed that infected worms display hallmarks of neurodegeneration similar to those seen in humans, but infertile animals resist this process.

How fast you move can predict how healthy you'll be

Researchers discover regulatory mechanism that extends 'healthspan', the time an organism is at its optimal health, using C. elegans roundworms. Maximum velocity (MV) of wild-type worms at day 9 adulthood reliably predicts longevity and physical decline.

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Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

Acorn worm genome reveals gill origins of human pharynx

The acorn worm's genome has revealed the origin of the human pharynx, showing how gill slits evolved into the jaw and throat. The study found that humans and other terrestrial vertebrates retain vestigial gills in embryos, a trait shared with marine animals.

Fossil fireworm species named after rock musician

A fossilized muscle-worm, discovered by University of Bristol scientists, was named Rollinschaeta myoplena in honor of punk musician Henry Rollins. The discovery highlights exceptional preservation of soft tissues in fossils, providing details about extinct animals.

Our closest wormy cousins

Researchers sequenced acorn worm genomes to find similarities with human genes, establishing a distant connection. The study identified 8,600 shared gene families across deuterostomes, including humans, starfish, and frogs, suggesting a common ancestor that lived half a billion years ago.

Eggs without yolk can hatch too

Biologists from KU Leuven discovered that nematode eggs can hatch without egg yolk, defying the rule that no yolk means no offspring. The finding opens new avenues for deworming products without side effects on humans.

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Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.

Allergy is the price we pay for our immunity to parasites

A recent study published in PLOS Computational Biology identifies molecular similarities between environmental allergens and parasitic worm proteins, suggesting that allergy is a flawed immune response. The research provides tools for predicting protein molecules that may cause allergic reactions and could lead to new treatments.

Intestinal worms 'talk' to gut bacteria to boost immune system

Researchers found that intestinal worm infections can increase short-chain fatty acid production, activating receptors that influence the immune system. This discovery highlights the microbiome as a new pathway for helminths to modulate host immune function.

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Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

What metabolism could reveal about aging and mortality

Researchers used Caenorhabditis elegans worms to develop a method to predict lifespan based on metabolic profiles. The study found that middle age was a key turning point in aging, with normal lifespan worms aging 40% faster than long-lived counterparts at this stage.