Articles tagged with Worms
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Researchers at the University of Michigan have discovered that a single neuron in C. elegans can regulate both speed and direction of movement, routing information through multiple downstream neural circuits. This fundamental biological mechanism has implications for understanding human brain function.
Scientists have discovered that PP4 protein oversees DNA processing during sperm and egg generation for successful fertilization. The study found that PP4's activity becomes more crucial during aging, indicating a potential role in age-related fertility declines.
Researchers at Duke University have discovered a key gene that regulates the immune system's transition from high alert to recovery after an infection. The finding, published in PLOS Genetics, highlights the importance of cellular homeostasis in repairing tissue damage and eliminating bacterial toxins.
A recent study aimed to determine the role of free radicals in aging, but was refuted due to limitations with the measurement tool used. The researchers found that changes in pH levels inside mitochondria, rather than free radical release, were responsible for the signals detected by the probe.
Australian researchers successfully treated 12 participants with celiac disease using hookworms, increasing gluten tolerance by a factor of 60. The study suggests a potential new treatment for inflammatory diseases, including asthma and Crohn's disease.
Researchers found that critically ill ICU patients lose almost all of their gut microbes and those left are mostly pathogenic, leading to life-threatening sepsis. The study suggests that minimizing antibiotic use and stabilizing remaining microbes could improve patient outcomes.
Researchers from the University of Southern Denmark have found that nonylphenol inhibits earthworms' ability to protect cells from cold damage, making them more vulnerable. The study also revealed that phenanthrene has an opposite effect, increasing cell membrane fluidity and resistance to cold in both earthworms and springtails.
Scientists have discovered bacteria that can divide in lengths ranging from 3 to 45 micrometers, defying conventional cell division rules. This discovery has significant implications for understanding microbial biology and the potential impact of these microorganisms on human health.
Researchers at Duke University have made a surprising discovery about the role of calcium in pain sensation using Caenorhabditis elegans worms. Calcium flow through pain-sensing channels helps worms adapt to repeated painful stimuli by desensitizing them, suggesting a potential survival advantage.
A Yale-led analysis of genomic data reveals shared molecular toolkits in flies, worms, and humans, with comparable numbers of functioning genes and coordinated gene expression patterns. However, pseudogene regions show stark differences reflecting divergent evolutionary histories.
Comprehensive maps of epigenetic marks reveal patterns for safe restoration and provide a framework for testing disease models and drug candidates. These findings hold promise for diagnosing and treating diseases caused by gene expression deregulation, including cancer and autoimmune disorders.
Researchers at Stanford University School of Medicine have mapped the binding sites and cellular expression patterns of regulatory factors in fruit flies, roundworms, and humans. The study identifies shared and distinct patterns across species, shedding light on how genes are turned on and off.
Researchers found powerful commonalities in biological activity and regulation among species, reflecting their shared ancestry. The studies revealed similarities in gene expression patterns, DNA packaging, and chromatin organization across human, fly, and worm genomes.
Researchers have discovered a definitive link between ancient worm-like creature Hallucigenia and modern velvet worms. A new study reveals that claws play a crucial role in the connection between these two groups, shedding light on the evolutionary tree of life.
Research finds that parasitic nematodes use olfaction to locate hosts, with distinct odor profiles reflecting host specificity rather than relatedness. The study's findings suggest targeted traps or repellents could be developed to control nematode infections.
Researchers have developed an adhesive patterned after glue produced by the sandcastle worm, which may solve the problem of premature births resulting from fetal surgery. The new adhesive is water-borne and non-toxic, and has been shown to be effective in repairing punctures without swelling.
Researchers have identified a peptide from parasitic worms that suppresses the immune response and may provide relief for multiple sclerosis, psoriasis, rheumatoid arthritis, and lupus patients. The study paves the way for a new drug containing the peptide to be developed.
Researchers at Tel Aviv University have identified a genetic mechanism that enables worms to pass on the 'memory' of starvation to multiple generations through small RNA molecules. This discovery has potential implications for understanding human physiological responses to starvation and other challenges, such as anorexia nervosa.
When worms mate with different species, their bodies are unable to tolerate the aggressive sperm, resulting in sterility and death. The sperm's premature fertilization of eggs and subsequent damage to the ovaries lead to these outcomes.
A new study using roundworms reveals that starvation induces specific changes in small RNAs, which are inherited through at least three consecutive generations. The researchers found that these changes target genes involved in nutrition and result in a longer life span for the progeny of starved worms.
Researchers have successfully treated a neurodegenerative disease in worms using resveratrol, which could lead to new treatments for humans. The disease, adult onset neuronal lipofuscinosis, affects only 1 in 100,000 people and has no known cure.
Researchers have successfully created mutant worms that cannot get intoxicated by alcohol, opening up new possibilities for treating alcohol withdrawal. The modified human alcohol target used in the study only affects its response to alcohol, leaving other functions intact.
Researchers found that restricting food to nematode worms triggers a state of arrested development, allowing them to live twice as long as normal. The study hints at an easier way to achieve human longevity and has implications for cancer research.
Researchers have decoded the whipworm's genetic and biological information, which provides a solid basis for developing new interventions. The study has identified molecules used for tunnelling and how the immune system responds to infection.
A new species of Mediterranean worm lizard, Blanus mendezi, has been identified with the discovery of its first intact skull, providing insights into the evolution of this poorly known group of reptiles. The fossil, dated to 11.6 million years ago, features a well-preserved skull and vertebrae, shedding light on the species' history.
Researchers at UNC School of Medicine discovered that cellular interactions can affect aging and infertility in nematodes. Tweaking a specific signaling pathway allowed worms to overcome infertility while living longer lives.
Researchers have successfully cultured and studied the three-banded panther worm, a new model organism for understanding regeneration. The worm's ability to regenerate any body part has been linked to Wnt and Bmp signaling pathways, offering potential clues for human regenerative therapies.
A new research from the University of Southampton has identified a coral-eating flatworm as a potential threat to coral reefs. The researchers found that the small flatworm could cause significant damage to coral reefs due to its ability to mimic the appearance of its hosts.
A team of scientists identified a key regulator called FoxA that drives pharynx regeneration in planarian worms. The study reveals how stem cells sense loss of a structure and rebuild it, shedding light on the mechanisms behind regeneration in these animals.
A recent study by Syracuse University researchers found that popular smartphone activities can leave devices vulnerable to 'computer worms.' These worms, which can steal personal info and spread to friends' contacts, target HTML5-based apps. The team identified 14 vulnerable apps across Android, iOS, and Blackberry.
A new species of horseshoe worm, Phoronis emigi, has been discovered in Japan after a 62-year gap, shedding light on the global diversity of the Phoronida phylum. The discovery is significant as it highlights the need for further investigations to reveal additional species.
Researchers found that pesticides reduce earthworms' weight, affect their metabolism rate, and increase energy demand, ultimately hindering their reproduction and survival in contaminated soil. This study highlights the importance of considering the impact of pesticides on non-target organisms like earthworms.
Scientists are developing drugs that target the bacteria Wolbachia to kill parasitic worms causing river blindness and elephantiasis. The new treatment has already shown promise in depleting Wolbachia from infected worms.
A previously unidentified microscopic species of mite, Osperalycus tenerphagus, has been discovered on The Ohio State University campus. The mite, dubbed the 'Buckeye Dragon Mite', has a unique oral structure and is an extremophile, adapted to living in adverse environments.
Researchers at UMass Medical School develop a novel model to study the effects of vitamin B12 on gene expression and physiology in C. elegans worms. The study reveals that vitamin B12 regulates development through the methionine/SAM cycle and alleviates toxic buildups of propionic acid, leading to improved fertility.
A new study by Swiss Tropical and Public Health Institute found that a veterinary drug, Oxantel Pamoate, can effectively treat whipworm infections in children. The treatment combination showed significant reduction in worm eggs and improved health outcomes for the children.
Researchers at USC identify a gene that delays aging effects depending on dietary intake, suggesting a genetic basis for individual nutritional needs. This breakthrough may lead to tailored diets based on an individual's genetic makeup, potentially enhancing overall health and longevity.
Scientists have decoded the genome of Necator americanus, a blood-sucking parasite that infects an estimated 700 million people worldwide. The research reveals clues to how the worm invades and survives in humans, providing valuable insights for developing new diagnostic tools and vaccines.
A study published in PLOS Pathogens has identified a key player in the movement of schistosome parasites: serotonin receptors. The discovery opens up new avenues for developing targeted treatments against this parasitic flatworm, which affects millions worldwide and kills an estimated 250,000 people annually.
Male sperm and seminal fluid trigger pathways that cause female worms to dehydrate, prematurely age and die. The death of the female after she gives birth fits into a general framework of sperm competition observed in nature.
Researchers found that using hot baths to raise body temperature and worm eggs to stimulate immunoregulatory factors may attenuate symptoms of autism. The study suggests that inflammation may contribute to the disorder, and these novel approaches could be future treatment options.
Research by Plymouth University and the University of Exeter found that microplastic ingestion can decrease energy reserves in marine worms. The study also revealed that ingested plastic can deliver harmful chemicals to organisms, leading to reduced health. This has significant implications for the food chain and marine ecosystems.
Researchers found that males secrete signaling molecules that shorten the lifespan of hermaphroditic females by more than 20%. The effect persists even when genders are separated or females are sterile, indicating it's not due to physical stress or energy demands. Pheromone production is also linked to male-induced demise.
Researchers have found a modified version of a common human dietary supplement to be effective in curing lab animals infected with hookworms. The probiotic was found to be safe and potentially lethal to intestinal worms, offering new hope for treating the disease that affects 1.5 billion people globally.
A research team at Worcester Polytechnic Institute has developed a novel system to image brain activity in worms. The technology can be used to study the genetics and neural circuitry associated with animal behavior and screen early stage compounds aimed at treating autism, anxiety, depression, schizophrenia, and other brain disorders.
Researchers have found that the bioluminescent display of a marine worm produces a long-lasting blue glow through a slimy mucus secreted from its body. The mucus contains riboflavin, vitamin B2, which is acquired by the worm through its diet or symbiotic bacteria.
Researchers at Max Planck Institute for Evolutionary Biology find gene eud-1 that determines wide-mouthed predators and narrow-mouthed bacteria eaters, providing insight into phenotypic plasticity. The discovery sheds light on how organisms adapt to changing environments and challenges current understanding of evolutionary adaptations.
Researchers studied C. elegans worm's swimming patterns to gain insights into human health and disease, leading to potential applications in drug screening and designing smart soft robots. The study aims to provide powerful tools for developing sensitive screens to test drug compounds that affect nerve cells or muscles.
A study by the University of Manchester team has identified a new pathway regulating immune responses in the gut that can protect against infection. This finding holds promise for developing a protective immune response during parasite infestations, potentially addressing a major public health issue.
Researchers at the University of Copenhagen discovered that mir-79, a tiny molecule, plays a crucial role in regulating neural development in roundworms. By controlling the addition of specific sugars to signaling molecules, mir-79 guides nerve cell migration and ensures proper nervous system function. This finding has important implic...
A new study reveals that earthworms can survive for up to three weeks without water by entering a state of estivation, where they reduce their surface area exposure and seal themselves in a mucus-lined chamber. After rewetting, the earthworms were able to recover and regain their weight.
Researchers at UCSF have discovered a link between meal times and daily changes in the immune system. Eosinophils, previously thought to fight parasitic diseases, may actually help invaders, according to the study. This discovery could lead to new strategies for fighting chronic parasitic infection and allergies.
Researchers at Salk Institute use salt-sniffing roundworms to show how the nervous system processes sensory information, revealing a complex interplay between neurons and signaling molecules. Insulin is identified as a key player in mediating this process, acting rapidly to transfer information from one neuron to another.
Scientists have developed a high-speed imaging technique with single-neuron resolution that can record the activity of 70% of nerve cells in a worm's head. This breakthrough allows for detailed maps of how neurons are wired up in the brain and information on how networks interact in real time.
A team of researchers from the University of Michigan discovered that the loss of motor ability associated with aging begins in neurons and spreads to muscles. By stimulating neurons, they were able to reverse the decline in motor ability in roundworms and potentially develop a new treatment for human muscle decline.
Researchers have identified five enzymes essential to the survival of a parasitic worm infecting livestock worldwide, including two already studied as potential drug targets against other pathogens. The genome of Haemonchus contortus provides valuable insights into how treatments work and reveals new drug and vaccine targets.
Scientists have identified a key enzyme that enables simple neurons in worms to transform into more elaborate shapes under stress, which may hold clues for developing drugs to treat severe anxiety disorders. The study also found that these transformed worms become highly resistant to stress and can survive extreme conditions.
A new study has discovered a super-charged methane seep in the ocean off New Zealand that has created a unique food web. The presence of polychaetes worms, which consume bacteria enriched with methane, plays a critical role in stabilizing the ecosystem and preventing excessive greenhouse gas emissions.
Scientists discovered a molecular switch that regulates regeneration in flatworms, enabling them to grow heads complete with brain, eyes, and wiring. This breakthrough could lead to insights into why some animals regenerate while others don't, potentially informing regenerative therapies for humans.
Researchers have identified a pathway of self-destruction that triggers the spread of cell death in worms, causing a 'blue Grim Reaper' to track death through the body. This discovery sheds light on how ageing causes death and provides insights into preventing it.