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Capturing brain activity with sculpted light

Scientists have developed a high-speed imaging technique with single-neuron resolution that can record the activity of 70% of nerve cells in a worm's head. This breakthrough allows for detailed maps of how neurons are wired up in the brain and information on how networks interact in real time.

SourceUniversity of Vienna·JournalNature Methods·DateSep 9, 2013

Heading for regeneration

Scientists discovered a molecular switch that regulates regeneration in flatworms, enabling them to grow heads complete with brain, eyes, and wiring. This breakthrough could lead to insights into why some animals regenerate while others don't, potentially informing regenerative therapies for humans.

SourceMax-Planck-Gesellschaft·JournalNature·DateJul 24, 2013

Big name for a small worm

A newly discovered threadworm, Pristionchus maxplancki, has been named after physicist Max Planck in recognition of his contributions to the fields of evolution, genetics, and ecology. The worm was discovered on a stag beetle in Japan and is now being studied by researchers at the Max Planck Institute for Developmental Biology.

SourceMax-Planck-Gesellschaft·JournalZOOLOGICAL SCIENCE·DateJul 9, 2013

Wiggling worms make waves in gene pool

Researchers at Rice University analyzed thousands of mutant worms to identify genes controlling movement, revealing 87 new links in the process. The study also uncovered evidence for a protein-signaling pathway regulating locomotion, with implications for prioritizing genetic tests in humans.

SourceRice University·JournalProceedings of the National Academy of Sciences·DateJul 1, 2013

Study by Worcester Polytechnic Institute professor produces first edition of a bookworm's genome

Researchers at Worcester Polytechnic Institute have sequenced the genetic code of Panagrellus redivivus, a tiny nematode also known as the beer-mat worm. The study reveals nearly 24,000 putative genes and sheds light on animal biology, including differences between male and female organisms and unique adaptations of parasitic worms.

SourceWorcester Polytechnic Institute·JournalGenetics·DateApr 25, 2013

Bed of needles

Scientists developed an adhesive patch that uses swellable microneedle tips to secure skin grafts firmly in place over wounds. The invention offers a trauma- and infection-prone alternative to traditional staples and sutures.

SourceBrigham and Women's Hospital·JournalNature Communications·DateApr 16, 2013

How the worm turns

Researchers at UMass Chan Medical School reveal the molecular mechanism behind the roundworm's escape response, linking two separate actions coordinated by tyramine and its interaction with fast- and slow-acting receptors.

SourceUMass Chan Medical School·JournalPLOS Biology·DateApr 2, 2013

Mystery of 'zombie worm' development unveiled

A new study elucidates the reproductive strategy of bone-eating worms, shedding light on their postembryonic development and sexual maturation. The researchers observed the duration of the larval stage, male dwarfism, and rapid female spawning, enabling effective reproduction in a food-rich but isolated habitat.

Feed a cold, starve a fever…. and your worms!

Researchers found that during a nematode-induced inflammation, the immune system increases cholecystokinin levels, reducing leptin production, which drives defense mechanisms against the parasite. The study suggests a novel mechanism for parasite expulsion in intestinal infections.

SourcePLOS·JournalPLOS Pathogens·DateJan 17, 2013

A pattern given by nature

A new plant-parasitic nematode worm, Meloidoderita salina, was discovered in a tidal salt marsh at Mont Saint Michel Bay. The female nematode worm exhibits a unique hexagonal beaded pattern on its cystoids, which is the first observation of this type in nematode worms.

SourcePensoft Publishers·JournalZooKeys·DateDec 7, 2012

Uncovering complexity

A single type of neuron in Caenorhabditis elegans nerve cord encodes an entire sensorimotor loop, with feedback driving motion itself. The discovery reveals a sophisticated system allowing the worm to organize its movements through proprioceptive feedback.

SourceHarvard University·JournalNeuron·DateNov 21, 2012

Understanding the brain by controlling behavior

Researchers at Harvard University have successfully controlled the behavior of worms by manipulating their neurons with precise laser beams. By hijacking key neurons, they can instruct the worm to perform specific actions, such as turning in a desired direction or responding to fake sensory inputs.

SourceHarvard University·JournalNature·DateSep 23, 2012

Moving toward regeneration

Researchers at the Stowers Institute for Medical Research discovered that planarian stem cells, known as neoblasts, can mobilize and rebuild tissues lost to amputation. The team found that these stem cells remain pluripotent even in fully mature animals and migrate to the site of injury when needed.

Earthworms soak up heavy metal

Researchers found that three earthworm species can remove up to 75% of heavy metals from waste, producing rich compost without accumulating toxins in crops. The worms' digestive system facilitates the separation of metal ions, allowing for safe disposal of organic waste.

SourceInderscience Publishers·JournalInternational Journal of Environment and Waste Management·DateAug 16, 2012

How the worm knows where its nose is

Researchers have discovered compartmentalized neural activity in nematode neurons, which enables movement and encodes body position. This finding has significant implications for understanding neurological disorders like schizophrenia and developing potential treatments.

SourceHarvard University·JournalNature·DateMay 16, 2012