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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Obstacles no barrier to higher speeds for worms, NYU researchers find

Researchers at New York University's Applied Math Lab found that obstacles can aid worm movement, contrary to common assumptions. The study, published in the Journal of the Royal Society Interface, used experiments and computer simulations to demonstrate how C. elegans worms navigate through lattice-like environments with ease.

Tiny amounts of alcohol dramatically extend a worm's life, but why?

Researchers found that minuscule amounts of ethanol double the life span of a tiny worm, while higher concentrations are harmful. The discovery raises intriguing possibilities for human health benefits, but more research is needed to understand the mechanism behind this effect.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Flatworm flouts fundamental rule of biology

Researchers have discovered that flatworms can regenerate without centrosomes, a cellular structure essential for cell division in all animals. This finding challenges the long-held assumption that centrosomes are crucial for cell division.

Will Antarctic worms warm to changing climate?

Researchers at the University of Delaware are studying Antarctic worms to understand how they adapt to changing environments and survive in a warming world. By analyzing epigenetic changes in DNA methylation, scientists hope to gain insight into the impact of global warming on marine ecosystems.

Aging human bodies and aging human oocytes run on different clocks

Researchers found that aging human oocytes have a distinctive DNA signature that is reversed in insulin and TGF-beta mutants. In contrast, somatic cells require maintaining protein and cell quality to combat aging. The study's findings could lead to ways to delay oocyte aging and reduce birth defects.

Acquired traits can be inherited via small RNAs

Scientists have discovered that roundworms can pass on immunity to a virus through small RNA molecules, which were not dependent on the organism's genome. This finding suggests that Lamarckian inheritance may provide adaptive advantages to an animal by allowing them to hold onto beneficial genes until needed.

Microscopic worms could hold the key to living life on Mars

Scientists use Caenorhabditis elegans to study the effects of long-duration space exploration on humans. The worms develop and reproduce in space just like on Earth, making them an ideal model for investigating the challenges of Martian habitation.

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Worms reveal secrets of wound-healing response

Biologists discovered genes in roundworms that signal wound presence and trigger chemical reactions to close cuts. The study also identified a protein that inhibits wound closure, raising hopes for developing treatments.

Parkinsonian worms may hold the key to identifying drugs for Parkinson's disease

Dopamine-deficient C. elegans worms offer a promising new approach to identifying potential treatments for Parkinson's disease, with researchers able to test over 1,000 drugs per year. The 'motor switching' problem faced by people with Parkinson's can be replicated in the worms, allowing scientists to quickly identify effective therapies.

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New drug targets revealed from giant parasitic worm genome sequence

Researchers have identified five high-priority drug targets for the parasitic disease ascariasis, caused by the giant intestinal roundworm Ascaris suum. The discovery provides new insights into treating the condition, which affects millions of people in developing countries and causes chronic effects in young children.

Cells are crawling all over our bodies, but how?

Biologists at Florida State University devise novel method to replicate cell motility in vitro using worm sperm, revealing unprecedented insight into cell crawling mechanisms. This breakthrough has significant implications for understanding human health and developing therapies to combat cancer.

Reversing aging

Researchers at UT Austin develop automated system to test millions of drugs on C. elegans worm, which develops Alzheimer's disease similar to humans. The goal is to speed up drug discovery and development for neurodegenerative diseases.

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Worm 'cell death' discovery could lead to new drugs for deadly parasite

Researchers from the Walter and Eliza Hall Institute have identified a 'programmed cell death' pathway in parasitic worms that could one day lead to new treatments for schistosomiasis. The discovery was made by studying programmed cell death in human cells, where the team found similarities with the process in fluke worms.

Evolution keeps sex determination flexible

Researchers at Michigan State University found that organisms quickly evolve ways to compensate for genetic and genomic disruptions in sex determination. The study used an experimental evolution approach to study adaptations in nematodes and showed that the mechanisms themselves are flexible and adaptable from an evolutionary viewpoint.

Recycling fat might help worms live longer

Researchers found that increased autophagy in germline-less worms led to higher activity of a fat-digesting enzyme, extending their lifespan. The study suggests that recycling fat is beneficial for worms, and may have implications for human diseases such as cancer and Alzheimer's.

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Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.

Brainy lizards pass test for birds

Researchers at Duke University found that tropical anoles can solve novel problems and remember solutions, demonstrating advanced cognitive abilities. The study's results challenge the notion that reptiles have limited cognitive capabilities and highlight the complexity of animal cognition.

How cavity-causing microbes invade heart

Researchers at the University of Rochester Medical Center identified a collagen-binding protein allowing Streptococcus mutans to invade heart tissue, causing endocarditis. The discovery may lead to a screening tool to gauge dental patients' vulnerability.

Microscopic worms could help open up travel into deep space

A team of scientists flew microscopic worms into space to test the effectiveness of RNA interference (RNAi) as a treatment for muscle degradation caused by space travel. The experiment showed promising results, suggesting that RNAi could be used to prevent muscle loss in astronauts and help people suffering from similar conditions.

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Worm study yields insights on humans, parasites and iron deficiency

Researchers at the University of Maryland have identified a protein called HRG-3 that transports heme from the mother's intestine to her developing embryos in C. elegans. This finding could lead to new treatments for parasitic worm infections and iron deficiency, affecting over two billion people worldwide.

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NIH scientists identify most proteins made by parasitic worm

A team of NIH scientists has identified the most proteins produced by Brugia malayi, a parasitic worm that causes lymphatic filariasis. The findings may lead to the development of new vaccines and treatments for the disease, which can cause severely disabling swelling in the lower limbs.

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Worm discovery could help 1 billion people worldwide

Researchers at the University of Manchester have identified a key component of human and animal gut mucus that is toxic to parasitic worms, which cause up to 1 billion deaths and illnesses globally. The discovery may lead to new treatments for chronic worm infections and help identify who is susceptible to parasitic worms.

Worm studies shed light on human cancers

Researchers discovered a worm protein controlling growth factor secretion, which is linked to human cancers. The study proposes that abnormal growth factor secretion may stimulate cancer formation and offers a potential targeted treatment approach.

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Dine or dash? Genes help decide when to look for new food

Researchers found that natural variations in several genes affect how quickly worms leave a lawn of bacteria. The tyra-3 gene is involved, producing a receptor activated by adrenaline-like hormones derived from the amino acid tyrosine.

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Worms strike see-saw balance in disease resistance

Researchers found that C. elegans worms gain resistance to one microbe at the cost of becoming more vulnerable to another, highlighting a see-saw balance between immunity to different diseases across the animal kingdom.

Trichinosis parasite gets DNA decoded

Researchers at Washington University School of Medicine have decoded the genome of Trichinella spiralis, a parasite that causes trichinosis, identifying unique features and novel genes that could lead to effective treatments. The study has implications for understanding parasitic diseases worldwide.

Xenacoelomorpha -- a new phylum in the animal kingdom

International team of scientists has discovered a new phylum, Xenacoelomorpha, which rewrites the evolutionary history of animals. The discovery shows that simple marine worms like Xenoturbellida and Acoelomorpha are more closely related to complex organisms like humans and sea urchins than previously thought.

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Simple marine worms distantly related to humans

Research published in Nature reveals that simple marine worms Xenoturbella and Acoelomorpha are distantly related to humans and other complex species. The findings suggest that these organisms have evolved backwards into simpler forms, shedding light on the early stages of animal evolution.

Star performer in basic biology labs diagnosed with first virus

Researchers discover naturally occurring viral infections in C. elegans, a millimeter-long worm used extensively for decades to study many aspects of biology. The findings provide insights into the way viruses and their hosts interact, shedding light on fundamental phenomena such as RNA interference and cell self-destruction.

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Biologists' favorite worm gets viruses

Researchers found that the nematode C. elegans, a millimeter-long worm used extensively for decades to study biology, gets naturally occurring viral infections. The discovery means C. elegans is likely to help scientists study the way viruses and their hosts interact.

Researchers register new species using DNA-based description

Researchers at the University of Gothenburg have used DNA technology to describe and register a new species of ribbon worm. The development of this method could lead to faster and more efficient species registration, with potential benefits for understanding biological diversity.

Sharply focused on neurons, light controls a worm's behavior

Researchers developed an optogenetic device to control the behavior of Caenorhabditis elegans worms using pulses of blue and green light. They successfully activated or inactivated specific neurons or muscle cells, turning the worm into a virtual biorobot.

When less is more: How mitochondrial signals extend lifespan

Researchers at the Salk Institute found that slowing mitochondrial function in specific cells can extend the lifespan of an entire organism. The key finding is that a unique signal emanating from damaged mitochondria in nerve or gut cells extends lifespan, while disrupting this signal has no effect.

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Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

Breakthrough in worm research has implications for human disease studies

A team of researchers from Brandeis University and University of Nevada, Reno has discovered genes in C. elegans that exhibit gene expression oscillations with 24-hour cycles, shedding light on the mammalian circadian clock. This finding has significant implications for studying human disease genes through corresponding worm genes.

The worm that turned on heavy metal

Researchers use earthworms to treat wastewater and soil contaminated with nickel, chromium, vanadium, lead, arsenic, and mercury. The method shows promise as an inexpensive alternative to industrial cleanup methods.

Researchers discover how worms promote healing

Researchers discover that infection with Trichuris trichiura eggs increases mucus production in the colon, providing symptomatic relief from ulcerative colitis. The study identifies a shift from pro-inflammatory to anti-inflammatory immune cells, paving the way for potential helminth therapy.

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DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.

Researchers unlock how key drug kills tropical parasites

Scientists have discovered how ivermectin kills parasitic worms that cause river blindness and elephantiasis, enabling the development of new treatment avenues. The drug works by blocking parasite secretions, allowing the host's immune system to attack and kill the parasites.