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A toxic menu

A small marine worm can survive on poisonous carbon monoxide and hydrogen sulphide thanks to symbiotic bacteria that use these compounds to produce food for the worm. The worm has lost its entire digestive system over millions of years of evolution, relying solely on its symbionts for nutrition.

SourceMax-Planck-Gesellschaft·JournalProceedings of the National Academy of Sciences·DateApr 17, 2012

Decoding worm lingo

Researchers found that many nematodes communicate using the same types of small-molecule pheromones, revealing a universal nematode language. This discovery could lead to strategies to prevent unwanted nematode species and improve agricultural and healthcare industries.

SourceCalifornia Institute of Technology·JournalCurrent Biology·DateApr 12, 2012

Immortal worms defy aging

Planarian worms, a species of flatworm, have been found to maintain telomere length indefinitely, allowing them to regenerate tissues and cells without aging. This discovery sheds light on the mechanisms underlying their immortality and may shed new insights into alleviating aging in human cells.

SourceUniversity of Nottingham·JournalProceedings of the National Academy of Sciences·DateFeb 27, 2012

Parkinsonian worms may hold the key to identifying drugs for Parkinson's disease

Dopamine-deficient C. elegans worms offer a promising new approach to identifying potential treatments for Parkinson's disease, with researchers able to test over 1,000 drugs per year. The 'motor switching' problem faced by people with Parkinson's can be replicated in the worms, allowing scientists to quickly identify effective therapies.

SourceUniversity of Texas at Austin·JournalProceedings of the National Academy of Sciences·DateNov 10, 2011

Reversing aging

Researchers at UT Austin develop automated system to test millions of drugs on C. elegans worm, which develops Alzheimer's disease similar to humans. The goal is to speed up drug discovery and development for neurodegenerative diseases.

Worm 'cell death' discovery could lead to new drugs for deadly parasite

Researchers from the Walter and Eliza Hall Institute have identified a 'programmed cell death' pathway in parasitic worms that could one day lead to new treatments for schistosomiasis. The discovery was made by studying programmed cell death in human cells, where the team found similarities with the process in fluke worms.

SourceWalter and Eliza Hall Institute·JournalProceedings of the National Academy of Sciences·DateSep 27, 2011

Evolution keeps sex determination flexible

Researchers at Michigan State University found that organisms quickly evolve ways to compensate for genetic and genomic disruptions in sex determination. The study used an experimental evolution approach to study adaptations in nematodes and showed that the mechanisms themselves are flexible and adaptable from an evolutionary viewpoint.

SourceMichigan State University·JournalEvolution·DateSep 12, 2011

Recycling fat might help worms live longer

Researchers found that increased autophagy in germline-less worms led to higher activity of a fat-digesting enzyme, extending their lifespan. The study suggests that recycling fat is beneficial for worms, and may have implications for human diseases such as cancer and Alzheimer's.

SourceSanford Burnham Prebys·JournalCurrent Biology·DateSep 6, 2011

Brainy lizards pass test for birds

Researchers at Duke University found that tropical anoles can solve novel problems and remember solutions, demonstrating advanced cognitive abilities. The study's results challenge the notion that reptiles have limited cognitive capabilities and highlight the complexity of animal cognition.

SourceDuke University·JournalBiology Letters·DateJul 12, 2011

GW researchers show host Mta1 gene is required for optimal survival of schistosome parasites, a leading global cause of cancer

Researchers at George Washington University School of Medicine and Health Sciences have shown that the Mta1 gene is essential for Schistosoma haematobium to establish a productive infection and survival in the host. The study found that mice lacking the Mta1 gene were unable to support worm growth and egg production, highlighting the c...

Worm discovery could help 1 billion people worldwide

Researchers at the University of Manchester have identified a key component of human and animal gut mucus that is toxic to parasitic worms, which cause up to 1 billion deaths and illnesses globally. The discovery may lead to new treatments for chronic worm infections and help identify who is susceptible to parasitic worms.

SourceUniversity of Manchester·JournalJournal of Experimental Medicine·DateMay 5, 2011

Trichinosis parasite gets DNA decoded

Researchers at Washington University School of Medicine have decoded the genome of Trichinella spiralis, a parasite that causes trichinosis, identifying unique features and novel genes that could lead to effective treatments. The study has implications for understanding parasitic diseases worldwide.

SourceWashU Medicine·JournalNature Genetics·DateFeb 20, 2011

Star performer in basic biology labs diagnosed with first virus

Researchers discover naturally occurring viral infections in C. elegans, a millimeter-long worm used extensively for decades to study many aspects of biology. The findings provide insights into the way viruses and their hosts interact, shedding light on fundamental phenomena such as RNA interference and cell self-destruction.

SourcePLOS·JournalPLOS Biology·DateJan 25, 2011

Biologists' favorite worm gets viruses

Researchers found that the nematode C. elegans, a millimeter-long worm used extensively for decades to study biology, gets naturally occurring viral infections. The discovery means C. elegans is likely to help scientists study the way viruses and their hosts interact.

SourceWashU Medicine·JournalPLOS Biology·DateJan 25, 2011