Articles tagged with Cardiac Function
A meta-analysis of nearly 1,900 studies found that climbing stairs significantly reduces the risk of dying from cardiovascular disease. Regular stair climbing was associated with lower risks of heart-related problems and major cardiovascular conditions such as heart attack, stroke, and heart failure.
A team of researchers has developed a new way to study heart valve disorders by creating miniature, working models of the heart. The models, called assembloids, were grown from pluripotent adult stem cells and can be used to simulate various types of valve disorders, including mitral valve prolapse.
Researchers at USF Health Morsani College of Medicine have identified a promising strategy to protect cardiac function in people with Duchenne muscular dystrophy. The study found that the experimental drug Setanaxib preserved cardiac function and reduced scarring, suggesting NOX4 as a potential therapeutic target for future treatments.
A system developed by Kaunas University of Technology enables continuous heart rhythm monitoring, allowing for more detailed ECG recordings and remote transmission to doctors. The technology aims to address the diagnostic gap in cardiovascular diseases, particularly for post-stroke patients at risk of ischaemic stroke.
A new wearable monitoring system called OMEGA aims to replace outdated fetal heart rate monitoring technology with a unified real-time assessment of fetal oxygen delivery and adaptive capacity. The system could potentially reduce C-section rates and improve maternal and fetal health outcomes, saving millions in healthcare costs.
A Tulane University study found that being female is not a universal stroke risk factor for patients with atrial fibrillation (AFib), especially for those under 75. Women age 75 and older or with comorbidities have a higher stroke risk, suggesting a more personalized approach to prevention.
Researchers from The University of Osaka found that treatment with five mRNAs effectively promoted cardiac repair and extended survival in mice with heart failure. The study showed that simultaneous administration of five therapeutic mRNAs reduced heart tissue damage and improved heart function.
A new study found that a simple angiogram scoring system can identify patients whose heart muscle is still alive even when a major artery has been completely blocked. This breakthrough could change how cardiac patients are treated and help doctors make faster, more informed decisions.
Researchers found that hydroxychloroquine use was associated with better cardiovascular and cardiometabolic health outcomes in patients with discoid lupus erythematosus. The study also found a lower risk of hypertension, hyperlipidemia, type 2 diabetes, stroke, and coronary artery disease among hydroxychloroquine users.
Macrophages are among the earliest responders to heart injury, activating an inflammatory program that helps kickstart regeneration. The researchers found that dampening this response specifically in macrophages promotes blood vessel growth and heart muscle cell proliferation, both essential for regeneration.
A new study suggests that both very low and very high resting heart rates are associated with an increased risk of stroke. The research found a U-shaped pattern, with stroke risk lowest at heart rates of 60-69 bpm and highest at below 50 bpm or above 90 bpm.
A new study found that fur seals' heart rate peaks six to eight hours after returning to land, indicating a delayed recovery from the physiological costs of foraging at sea. This suggests that seals use their time onshore to actively recover and replenish oxygen stores.
A minimally invasive catheter ablation procedure has been shown to provide substantial benefits for patients with advanced forms of atrial fibrillation. By targeting faulty electrical signaling in the heart, the procedure can lead to improved control of the disease and reduced risk of serious adverse events.
A simple ECG test can identify racehorses at risk of cardiac arrhythmias during high-intensity exercise. The test uses short ECG recordings taken at rest or light exercise to distinguish horses likely to develop premature beats.
A study published in Brain Medicine suggests autonomic dysfunction, particularly parasympathetic and sympathetic imbalances, contributes to depressive symptoms in patients unresponsive to conventional antidepressants. Low-dose medications targeting these imbalances may offer a new approach to treatment.
A new study from Tulane University found that women with high predicted cardiovascular risk face nearly double the risk of hip fracture. The association was stronger in women under 65, and higher cardiovascular risk was linked to fractures in weakened bones in major areas.
A new study found that walking pace is a strong predictor of mortality risk, especially in people with existing health conditions. Combining walking pace with other physical measures improved mortality predictions, suggesting a simple and cost-effective way to identify high-risk individuals.
A new 4D digital heart model has been shown to improve patient outcomes in cardiac resynchronization therapy (CRT) for heart failure. The model, developed at the University of Calgary, enables personalized pacemaker placement, leading to a 10.8% increase in heart function compared to standard care.
A new biotech company, Ibnova Therapeutics, will accelerate treatments for heart disease through cellular therapies, backed by Australian and Danish partnerships. The company aims to conduct human clinical trials within three to five years.
A team from the Universitat Politècnica de València and Corify Care has developed the first whole-heart mapping technology that provides real-time views of cardiac arrhythmias. This innovation enables physicians to make faster decisions, target ablations more effectively, and potentially reduce procedure time.
A new study from CU Anschutz researchers found that regular physical activity can significantly lower post-ablation atrial fibrillation recurrence risk. Adults who engaged in moderate exercise for 30 minutes three times a week had markedly lower rates of AF recurrence compared to those who were less active.
Researchers have developed a non-invasive method to estimate blood oxygen levels in heart failure patients using standard cardiac MRI. This breakthrough could spare thousands from undergoing risky tube procedures, allowing for safer and more frequent monitoring.
A phase 2 clinical trial is comparing three strategies to protect heart health in prostate cancer patients undergoing hormone therapy. The study will assess the impact of intermittent fasting, GLP-1 medication, and nutritional counseling on cardiovascular and metabolic risks associated with androgen deprivation therapy.
Smartwatches with PPG and ECG functionality improve atrial fibrillation detection, detecting it four times more often than standard care. Researchers detected heart arrhythmia in 21 patients using smartwatches compared to five in those receiving standard care after six months of monitoring.
Researchers identify circulating extracellular vesicles produced in diseased kidneys as the culprit behind toxicity in the heart. The discovery could lead to the development of a blood test to identify patients at high risk for serious heart problems and novel treatments to prevent and treat heart failure.
Researchers identified bradycardia as a symptom of xylazine-opioid overdose, particularly in the Northeast, where xylazine is more prevalent. This finding may aid emergency medicine physicians in detecting xylazine exposure and providing harm reduction counseling.
A new study in Circulation: Population Health and Outcomes journal found that TV characters were more likely to receive CPR than real-life counterparts. This discrepancy highlights the need for accurate depictions of hands-only CPR on television.
A new study using advanced imaging found that abdominal obesity is associated with more harmful changes in heart structure than overall body weight alone. The research, presented at the Radiological Society of North America annual meeting, suggests that male patients may be more vulnerable to structural effects of obesity on the heart.
A new study found that middle-aged people with higher levels of cardiac troponin I in their blood were more likely to develop dementia in later life. The study also found that damage to the brain seen in people with dementia accumulates slowly over decades before symptoms develop.
Researchers used CRISPR technology to identify HMGN1, a nuclear binding protein that contributes to trisomy 21-related CHDs. The study found that an overabundance of HMGN1 leads to abnormal heart development and gene expression.
A new study has uncovered 42 genetic locations associated with hypertrophy of the left ventricle, a major risk factor for sudden death. The research, conducted using three-dimensional MRI images and genome-wide analysis, could lead to earlier identification of individuals at greater risk.
Fitter individuals have lower resting heart rates and use fewer total heartbeats per day compared to sedentary people. Regular exercise can improve heart function and reduce long-term cardiovascular risk, according to new Australian research.
Research from the University of Copenhagen shows that exercising in nature improves mood, reduces stress levels, and boosts heart rate. Participants who exercised outdoors reported greater joy, satisfaction, and optimism than those who exercised in urban or indoor environments.
A new report from Emory University reveals that certain mental health conditions can raise the risk of developing heart disease by 50-100% and adverse outcomes from existing heart conditions by 60-170%. The study emphasizes a bidirectional relationship between cardiovascular disease and mental health, highlighting the need for an integ...
Researchers have found subtle abnormalities in heart muscle function and blood pumping in young adults with bipolar disorder before the onset of heart failure. The study suggests a link between underlying coronary vascular dysfunction and cardiac impairment.
A novel analysis confirms the benefits of regular walking at a faster pace in improving health, particularly for low-income and Black populations. The study found that fast walking as little as 15 minutes a day was associated with a nearly 20% reduction in total mortality.
A new study from Emory University reveals that maintaining optimal cardiovascular health can significantly improve overall physical and psychological well-being. The review confirms that heart-healthy behaviors positively impact brain function, vision, hearing, muscle strength, and reduce the risk of chronic diseases.
A University of Cincinnati researcher is investigating how excess sugar impacts cardiovascular structure and function in people with diabetes. The study focuses on a protein called GLUT1, which becomes overactive in diabetes, leading to harmful changes at the cellular level.
Scientists at The University of Texas at Arlington identified a new enzyme, IDO1, that plays a crucial role in inflammation and cholesterol regulation. By blocking this enzyme, macrophages regain their ability to absorb cholesterol, offering a potential new way to prevent heart disease.
A cardiac magnetic resonance imaging (MRI) scan usually takes anywhere from 30 to 90 minutes. The AI-assisted model developed by Mizzou researchers can turn low-quality MRI heart scans into high-quality images in less time, while improving patient experience and reducing costs.
A global study by UniSA researchers found that 94% of people who use wearable activity trackers are open to sharing their health information with healthcare providers. This could lead to more personalized and responsive care. The demand for personalized healthcare is on the rise, and wearable activity tracker market is increasing.
Exposure to lingering fine particulate matter from wildfire smoke was associated with increased hospitalization risks for various cardiorespiratory conditions, including ischemic heart disease and respiratory diseases. The study's findings highlight the need for research into the long-term health impacts of wildfire smoke.
A study found that adults hospitalized for RSV had significantly higher odds of cardiac events compared to those with COVID-19 or influenza. The findings suggest that preexisting cardiovascular risk patients should consider vaccination against respiratory viral infections.
People who sit for more than 14 hours a day may have a higher risk of cardiovascular events or death after treatment for heart attack symptoms. Replacing sedentary time with sleep reduces the risk, according to new research published in Circulation: Cardiovascular Quality and Outcomes.
Researchers developed a new imaging technique that uses artificial intelligence and high-speed microscopy to track platelet behavior in real-time. The study shows promise for personalizing heart disease treatment by monitoring clotting risk in patients with coronary artery disease.
The American Heart Association has awarded $900,000 to four organizations to improve food access in under-resourced communities through the Bernard J. Tyson Impact Fund. The funding supports social enterprises that specifically address food security, particularly among mothers, infants, and people with diabetes.
The American Society for Nutrition's annual conference will showcase the latest research on nutrition science and its applications. NUTRITION 2025 will highlight key areas such as chronic pain, ultra-processed foods, obesity medicines, and adolescent health, featuring expert discussions and research updates.
Researchers have identified a link between reduced pulse rate complexity and faster cognitive decline in older adults. The study found that people with more complex heartbeats tend to experience slower cognitive decline over time.
Researchers at University of East Anglia developed 4D flow MRI scan to diagnose aortic stenosis more accurately and reliably than current ultrasound techniques. The technology offers more accurate measurements of blood flow through heart valves, leading to better prediction of when patients need surgery.
A new study identified 56 non-clinical risk factors associated with sudden cardiac arrest (SCA), finding that improving unfavorable profiles could prevent up to 63% of SCA cases. Lifestyle habits and environmental factors were found to be the most impactful in preventing SCA cases.
The World Sleep Society releases recommendations on wearable sleep trackers, providing clear guidelines for consumers, clinicians, researchers, and manufacturers. Key takeaways include choosing a device suitable for individual use cases and focusing on fundamental sleep measures rather than specific stages of sleep.
A team of researchers has developed a gene-therapy strategy to treat arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5), a rare and deadly hereditary disease. The treatment, using adeno-associated viruses, improved cardiac function and prolonged survival in mice with ARVC5-like disease.
Scientists have discovered that early-life cardiac injury in parents can alter heart development and function in offspring, leading to improved cardiac remodeling and increased blood ejection volume. This finding suggests a potential long-term impact on cardiovascular health.
Early IABP use did not improve 60-day survival or transition patients to long-term treatment compared to standard medical care. The trial found that the device offered no additional benefit, leading to its early termination.
A new antidote, bentracimab, safely restored platelet function in patients on ticagrelor, reducing the risk of bleeding during urgent surgery or major bleeding events. The study showed similar results for surgical and bleeding patients, with 94.3% achieving normal blood clotting after treatment.
Adult patients with congenital heart disease have poor exercise capacity due to increased sedentary behavior. Increasing moderate-to-vigorous physical activity for 10 minutes daily can boost peak oxygen uptake by up to 0.454 mL/min/kg, suggesting a positive impact on prognosis and mobility.
Myotonic Dystrophy Type 1 affects multiple organs, including the heart, and is caused by a mutation in the DMPK gene that leads to disrupted RNA processing. Researchers at Baylor College of Medicine tested MBNL overexpression in a mouse model, achieving partial rescue of cardiac phenotypes.
The study found that tunneling nanotube-like structures connect cells in the heart, enabling long-distance intercellular communication essential for heart formation. Disruption of these structures resulted in impaired ventricular wall morphogenesis and defective myocardial growth.
A new study from Karolinska Institutet found that patients with heart failure who stop taking medications like RASi, ARNi, or MRA have a higher risk of heart-related death or hospitalization. Despite improved symptoms and pump function, continued medication is crucial to prevent complications.
A new Emory University study reveals that childhood trauma can physically alter the hearts of Black women, leading to worse vascular function and a higher risk of heart disease. Women are more vulnerable to this effect due to different forms of trauma exposure.