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The Lancet Diabetes & Endocrinology: Gradual weight loss no better than rapid weight loss for long-term weight control

A new study published in The Lancet Diabetes & Endocrinology found that gradual weight loss is not more effective than rapid weight loss for achieving long-term weight control. In the trial, participants who lost weight quickly were more likely to achieve target weight loss and had lower drop-out rates.

SourceThe Lancet·JournalThe Lancet Diabetes & Endocrinology·DateOct 15, 2014

The Lancet Diabetes & Endocrinology: Vitamin D supplements have little effect on risk of falls in older people

A new meta-analysis suggests that vitamin D supplements do not prevent falls by 15% or more, leaving uncertainty about their benefits for vulnerable older people. The analysis of 20 randomised controlled trials involving over 29,500 participants found no evidence to support the use of vitamin D supplements to reduce fall risk.

SourceThe Lancet·JournalThe Lancet Diabetes & Endocrinology·DateApr 23, 2014

New analysis suggests that further trials of vitamin D have little chance of showing health benefits

A new analysis of 40 randomized controlled trials suggests that vitamin D supplementation does not prevent heart attacks, strokes, or bone fractures. The study concludes that vitamin D supplements probably provide little to no health benefit, contradicting previous observational studies that linked deficiency to poor health.

SourceThe Lancet_DELETED·JournalThe Lancet Diabetes & Endocrinology·DateJan 23, 2014

Exposure to cold temperatures can help boost weight loss

Researchers found that mild cold exposure can significantly affect energy expenditure over sustained time periods, suggesting a potential benefit for weight loss. Brown fat, a heat-generating organ thought to be active only in infants, is also present in adults and can be activated by cold temperatures.

SourceCell Press·JournalTrends in Endocrinology and Metabolism·DateJan 22, 2014

The dark side of artificial sweeteners

Consuming artificial sweeteners has been associated with an increased risk of obesity, type 2 diabetes, and metabolic syndrome. Regular consumption can also lead to altered brain activation patterns and overindulgence in high-calorie foods.

SourceCell Press·JournalTrends in Endocrinology and Metabolism·DateJul 10, 2013

Glucosamine causes the death of pancreatic cells

High doses of glucosamine can cause the death of pancreatic cells, potentially increasing the risk of developing diabetes. Research by Université Laval's Faculty of Pharmacy found that prolonged exposure to glucosamine triggers a mechanism that negatively affects cell survival in the pancreas.

SourceUniversité Laval·JournalJournal of Endocrinology·DateOct 27, 2010

Hope for men with nonobstructive infertility

A recent study published in Reproductive Biology and Endocrinology found that sperm from men with non-obstructive azoospermia are equally capable of producing embryos through intracytoplasmic sperm injection (ICSI). The study also showed that there were no significant differences in implantation rates or clinical pregnancy rates betwee...

SourceBMC (BioMed Central)·JournalReproductive Biology and Endocrinology·DateDec 2, 2009

Fracture risk following bariatric surgery

Researchers at Mayo Clinic have found that bariatric surgery may be associated with an increased risk of fractures, particularly in the hands and feet. The study, which analyzed nearly 100 surgical cases over a 21-year period, showed that 21 individuals experienced 31 fractures within seven years after surgery.

Low vitamin D causes problems for acutely ill patients

A study of ICU patients found that 45% were deficient in vitamin D, with lower levels associated with greater disease severity. Researchers believe that vitamin D deficiency may contribute to disease complications and suggest that raising vitamin D levels may be beneficial for critically ill patients.

SourceResearch Australia·JournalNew England Journal of Medicine·DateApr 30, 2009